BRPI0507670A - moduladores do receptor de androgênio - Google Patents

moduladores do receptor de androgênio

Info

Publication number
BRPI0507670A
BRPI0507670A BRPI0507670-6A BRPI0507670A BRPI0507670A BR PI0507670 A BRPI0507670 A BR PI0507670A BR PI0507670 A BRPI0507670 A BR PI0507670A BR PI0507670 A BRPI0507670 A BR PI0507670A
Authority
BR
Brazil
Prior art keywords
androgen receptor
receptor modulators
modulators
androgen
oxobenzonitriles
Prior art date
Application number
BRPI0507670-6A
Other languages
English (en)
Inventor
Lain-Yen Hu
Huangshu Lei
Daniel Yunlong Du
Bruce Allen Lefker
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of BRPI0507670A publication Critical patent/BRPI0507670A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

MODULADORES DO RECPTOR DE ANDROGêNIO A presnete invenção refer-se a uma nova classe de 4-oxobenzonitrilas, o uso das mesmas como moduladores de androgênio e ao seu uso para o tratamento da alopecia.
BRPI0507670-6A 2004-02-13 2005-01-31 moduladores do receptor de androgênio BRPI0507670A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54473804P 2004-02-13 2004-02-13
US60564704P 2004-08-30 2004-08-30
PCT/IB2005/000229 WO2005080320A1 (en) 2004-02-13 2005-01-31 Androgen receptor modulators

Publications (1)

Publication Number Publication Date
BRPI0507670A true BRPI0507670A (pt) 2007-07-17

Family

ID=34890476

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507670-6A BRPI0507670A (pt) 2004-02-13 2005-01-31 moduladores do receptor de androgênio

Country Status (20)

Country Link
US (1) US7576128B2 (pt)
EP (1) EP1716110A1 (pt)
JP (1) JP3997255B2 (pt)
KR (1) KR100783255B1 (pt)
AP (1) AP2006003700A0 (pt)
AR (1) AR047606A1 (pt)
AU (1) AU2005214167B2 (pt)
BR (1) BRPI0507670A (pt)
CA (1) CA2554696C (pt)
CR (1) CR8555A (pt)
EA (1) EA009902B1 (pt)
EC (1) ECSP066761A (pt)
IL (1) IL176935A0 (pt)
MA (1) MA28361A1 (pt)
NO (1) NO20064053L (pt)
PA (1) PA8623501A1 (pt)
PE (1) PE20051168A1 (pt)
TW (1) TW200534842A (pt)
UY (1) UY28746A1 (pt)
WO (1) WO2005080320A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2554696C (en) 2004-02-13 2009-06-30 Warner-Lambert Company Llc Androgen receptor modulators
WO2005100305A1 (en) 2004-04-13 2005-10-27 Warner-Lambert Company Llc Androgen modulators
JP2007533726A (ja) 2004-04-22 2007-11-22 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー アンドロゲンモジュレーター
MXPA06015169A (es) 2004-07-08 2007-08-21 Warner Lambert Co Moduladores de androgenos.
EP1781599A1 (en) * 2004-08-18 2007-05-09 Warner-Lambert Company LLC Androgen modulators
KR20070049238A (ko) * 2004-08-31 2007-05-10 워너-램버트 캄파니 엘엘씨 안드로겐 조절제
TW200724139A (en) 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators
TW200708499A (en) * 2005-06-22 2007-03-01 Warner Lambert Co Process for producing ethers
WO2007007149A1 (en) * 2005-07-12 2007-01-18 Warner-Lambert Company Llc Androgen modulators
US20090170886A1 (en) * 2005-08-08 2009-07-02 Pfizer Inc Androgen modulators
EP3108879A1 (en) 2015-06-25 2016-12-28 Cassiopea S.p.A. High concentration formulation
HUE066348T2 (hu) 2018-08-07 2024-07-28 Univ Emory Heterociklusos flavon-származékok és az ezekhez kapcsolódó készítmények és eljárások

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Also Published As

Publication number Publication date
TW200534842A (en) 2005-11-01
US20050182132A1 (en) 2005-08-18
AP2006003700A0 (en) 2006-08-31
CA2554696C (en) 2009-06-30
NO20064053L (no) 2006-11-08
KR100783255B1 (ko) 2007-12-06
CR8555A (es) 2006-10-17
CA2554696A1 (en) 2005-09-01
AU2005214167A1 (en) 2005-09-01
EA009902B1 (ru) 2008-04-28
JP3997255B2 (ja) 2007-10-24
AR047606A1 (es) 2006-01-25
WO2005080320A1 (en) 2005-09-01
KR20060116223A (ko) 2006-11-14
EA200601267A1 (ru) 2006-12-29
EP1716110A1 (en) 2006-11-02
JP2007522199A (ja) 2007-08-09
AU2005214167B2 (en) 2008-08-07
PE20051168A1 (es) 2006-02-18
US7576128B2 (en) 2009-08-18
MA28361A1 (fr) 2006-12-01
IL176935A0 (en) 2006-12-10
PA8623501A1 (es) 2005-08-30
ECSP066761A (es) 2006-11-16
UY28746A1 (es) 2005-09-30

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