ECSP088115A - Procedimiento para la preparación de compuestos de 1-[ciano(4-hidroxifenil)metil]ciclohexanol - Google Patents

Procedimiento para la preparación de compuestos de 1-[ciano(4-hidroxifenil)metil]ciclohexanol

Info

Publication number
ECSP088115A
ECSP088115A EC2008008115A ECSP088115A ECSP088115A EC SP088115 A ECSP088115 A EC SP088115A EC 2008008115 A EC2008008115 A EC 2008008115A EC SP088115 A ECSP088115 A EC SP088115A EC SP088115 A ECSP088115 A EC SP088115A
Authority
EC
Ecuador
Prior art keywords
methyl
preparation
compounds
ciclohexanol
hydroxyphenyl
Prior art date
Application number
EC2008008115A
Other languages
English (en)
Inventor
Beat Theodor Weber
Hans-Rudolf Marti
Frieder Mitzel
Richard Haldimann
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ECSP088115A publication Critical patent/ECSP088115A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/36—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Procedimiento para la preparación de compuestos de 1-[ciano(fenil)metil]ciclohexanol de la fórmula general (I): en donde R1 es hidrógeno, alquilo (C1-4) o alcoxi (C1-4), caracterizado porque se hace reaccionar un compuesto de la fórmula general (II): en donde R1 tiene los significados indicados con anterioridad, con ciclohexanona, en donde la reacción se lleva a cabo en presencia de una base orgánica o inorgánica y esta base orgánica o inorgánica está presente en al menos una cantidad equimolar respecto de la cantidad de compuesto de la fórmula general (II) en la mezcla de reacción.
EC2008008115A 2005-06-29 2008-01-17 Procedimiento para la preparación de compuestos de 1-[ciano(4-hidroxifenil)metil]ciclohexanol ECSP088115A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH11012005 2005-06-29

Publications (1)

Publication Number Publication Date
ECSP088115A true ECSP088115A (es) 2008-02-20

Family

ID=35945318

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008115A ECSP088115A (es) 2005-06-29 2008-01-17 Procedimiento para la preparación de compuestos de 1-[ciano(4-hidroxifenil)metil]ciclohexanol

Country Status (21)

Country Link
US (1) US20070021627A1 (es)
EP (1) EP1902015A1 (es)
JP (1) JP2008546818A (es)
KR (1) KR20080031910A (es)
CN (1) CN101238094A (es)
AR (1) AR057416A1 (es)
AU (1) AU2006264012A1 (es)
BR (1) BRPI0612896A2 (es)
CA (1) CA2613689A1 (es)
CR (1) CR9665A (es)
EC (1) ECSP088115A (es)
GT (1) GT200600284A (es)
IL (1) IL188070A0 (es)
MX (1) MX2007016049A (es)
NO (1) NO20080447L (es)
PE (1) PE20070326A1 (es)
RU (1) RU2008103285A (es)
SV (1) SV2007002591A (es)
TW (1) TW200704632A (es)
WO (1) WO2007000294A1 (es)
ZA (1) ZA200800746B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007047972A2 (en) * 2005-10-19 2007-04-26 Teva Pharmaceutical Industries Ltd. Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
JP4763788B2 (ja) * 2006-07-26 2011-08-31 テバ ファーマシューティカル インダストリーズ リミティド Ｏ−デスメチルベンラファキシンの合成方法
US20080183016A1 (en) * 2006-07-26 2008-07-31 Valerie Niddam-Hildesheim Process for the synthesis of O-desmethylvenlafaxine
CA2795023A1 (en) 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Crystal forms of o-desmethylvenlafaxine fumarate
DK201500161U3 (da) * 2015-12-30 2016-04-25 Ke Aarhus Holding Aps Informationsterminal til montage på kundevogn

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56324B1 (en) * 1982-12-13 1991-06-19 American Home Prod Phenethylamine derivatives and intermediates therefor
JP2002006225A (ja) * 2000-06-23 2002-01-09 Nikon Corp 顕微鏡照明装置
US6504044B2 (en) * 2001-02-28 2003-01-07 Council Of Scientific And Industrial Research Process for the preparation of 1-[cyano(aryl)methyl] cyclohexanol
KR20030000217A (ko) * 2001-06-22 2003-01-06 와이어쓰 시클로헥사놀 유도체의 제조방법

Also Published As

Publication number Publication date
NO20080447L (no) 2008-01-23
AU2006264012A1 (en) 2007-01-04
TW200704632A (en) 2007-02-01
PE20070326A1 (es) 2007-05-30
US20070021627A1 (en) 2007-01-25
ZA200800746B (en) 2009-02-25
RU2008103285A (ru) 2009-08-10
WO2007000294A1 (en) 2007-01-04
GT200600284A (es) 2007-09-05
CA2613689A1 (en) 2007-01-04
SV2007002591A (es) 2007-02-27
AR057416A1 (es) 2007-12-05
EP1902015A1 (en) 2008-03-26
IL188070A0 (en) 2008-03-20
KR20080031910A (ko) 2008-04-11
CR9665A (es) 2008-08-21
BRPI0612896A2 (pt) 2009-12-08
JP2008546818A (ja) 2008-12-25
MX2007016049A (es) 2008-03-10
CN101238094A (zh) 2008-08-06

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