BRPI0612896A2 - processo para a preparação de compostos de 1 - [ciano (fenil) metil] cicloexanol - Google Patents

processo para a preparação de compostos de 1 - [ciano (fenil) metil] cicloexanol

Info

Publication number
BRPI0612896A2
BRPI0612896A2 BRPI0612896-3A BRPI0612896A BRPI0612896A2 BR PI0612896 A2 BRPI0612896 A2 BR PI0612896A2 BR PI0612896 A BRPI0612896 A BR PI0612896A BR PI0612896 A2 BRPI0612896 A2 BR PI0612896A2
Authority
BR
Brazil
Prior art keywords
methyl
cyano
phenyl
preparation
compounds
Prior art date
Application number
BRPI0612896-3A
Other languages
English (en)
Inventor
Frieder Mitzel
Beat Theodor Weber
Hans-Rudolf Marti
Richard Haldimann
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BRPI0612896A2 publication Critical patent/BRPI0612896A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/36—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCESSO PARA A PREPARAçãO DE COMPOSTOS DE 1-[CIANO(FENIL)METIL] CICLOEXANOL. é descrito um processo para a preparação de compostos de 1-[ciano (fenil) metil] cicloexanol de fórmula geral (I), em que R~ 1~ é hidrogênio, alquila (C~ 1-4~) ou alcóxi (C~ 1-4~), em que um composto de fórmula geral (II), em que R~ 1~ é da forma definida anteriormente, reage com cicloexanona, a reação sendo realizada na presença de uma base orgânica ou inorgânica, e esta base orgânica ou inorgânica estando presente na mistura da reação em pelo menos uma quantidade equimolar, com base na quantidade do composto da fórmula geral (II).
BRPI0612896-3A 2005-06-29 2006-06-26 processo para a preparação de compostos de 1 - [ciano (fenil) metil] cicloexanol BRPI0612896A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH11012005 2005-06-29
PCT/EP2006/006126 WO2007000294A1 (en) 2005-06-29 2006-06-26 Process for the preparation of 1-[cyano (4-hydroxyphenyl)methyl]cyclohexanol compounds

Publications (1)

Publication Number Publication Date
BRPI0612896A2 true BRPI0612896A2 (pt) 2009-12-08

Family

ID=35945318

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0612896-3A BRPI0612896A2 (pt) 2005-06-29 2006-06-26 processo para a preparação de compostos de 1 - [ciano (fenil) metil] cicloexanol

Country Status (21)

Country Link
US (1) US20070021627A1 (pt)
EP (1) EP1902015A1 (pt)
JP (1) JP2008546818A (pt)
KR (1) KR20080031910A (pt)
CN (1) CN101238094A (pt)
AR (1) AR057416A1 (pt)
AU (1) AU2006264012A1 (pt)
BR (1) BRPI0612896A2 (pt)
CA (1) CA2613689A1 (pt)
CR (1) CR9665A (pt)
EC (1) ECSP088115A (pt)
GT (1) GT200600284A (pt)
IL (1) IL188070A0 (pt)
MX (1) MX2007016049A (pt)
NO (1) NO20080447L (pt)
PE (1) PE20070326A1 (pt)
RU (1) RU2008103285A (pt)
SV (1) SV2007002591A (pt)
TW (1) TW200704632A (pt)
WO (1) WO2007000294A1 (pt)
ZA (1) ZA200800746B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007047972A2 (en) * 2005-10-19 2007-04-26 Teva Pharmaceutical Industries Ltd. Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
JP4763788B2 (ja) * 2006-07-26 2011-08-31 テバ ファーマシューティカル インダストリーズ リミティド Ｏ−デスメチルベンラファキシンの合成方法
US20080183016A1 (en) * 2006-07-26 2008-07-31 Valerie Niddam-Hildesheim Process for the synthesis of O-desmethylvenlafaxine
CA2795023A1 (en) 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Crystal forms of o-desmethylvenlafaxine fumarate
DK201500161U3 (da) * 2015-12-30 2016-04-25 Ke Aarhus Holding Aps Informationsterminal til montage på kundevogn

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56324B1 (en) * 1982-12-13 1991-06-19 American Home Prod Phenethylamine derivatives and intermediates therefor
JP2002006225A (ja) * 2000-06-23 2002-01-09 Nikon Corp 顕微鏡照明装置
US6504044B2 (en) * 2001-02-28 2003-01-07 Council Of Scientific And Industrial Research Process for the preparation of 1-[cyano(aryl)methyl] cyclohexanol
KR20030000217A (ko) * 2001-06-22 2003-01-06 와이어쓰 시클로헥사놀 유도체의 제조방법

Also Published As

Publication number Publication date
NO20080447L (no) 2008-01-23
AU2006264012A1 (en) 2007-01-04
TW200704632A (en) 2007-02-01
PE20070326A1 (es) 2007-05-30
US20070021627A1 (en) 2007-01-25
ZA200800746B (en) 2009-02-25
RU2008103285A (ru) 2009-08-10
WO2007000294A1 (en) 2007-01-04
GT200600284A (es) 2007-09-05
CA2613689A1 (en) 2007-01-04
SV2007002591A (es) 2007-02-27
AR057416A1 (es) 2007-12-05
EP1902015A1 (en) 2008-03-26
IL188070A0 (en) 2008-03-20
KR20080031910A (ko) 2008-04-11
CR9665A (es) 2008-08-21
ECSP088115A (es) 2008-02-20
JP2008546818A (ja) 2008-12-25
MX2007016049A (es) 2008-03-10
CN101238094A (zh) 2008-08-06

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Legal Events

Date Code Title Description
B10A Cessation: cessation confirmed

Free format text: HOMOLOGADA A DESISTENCIA DO PEDIDO, SOLICITADA ATRAVES DA PETICAO NO 20090073088/RJ DE 29.07.2009.