ECSP088300A - Derivados de benzotiadiazolilfenilalquilamina para uso en el tratamiento de condiciones mejoradas por la retoma de monoamina - Google Patents

Derivados de benzotiadiazolilfenilalquilamina para uso en el tratamiento de condiciones mejoradas por la retoma de monoamina

Info

Publication number
ECSP088300A
ECSP088300A EC2008008300A ECSP088300A ECSP088300A EC SP088300 A ECSP088300 A EC SP088300A EC 2008008300 A EC2008008300 A EC 2008008300A EC SP088300 A ECSP088300 A EC SP088300A EC SP088300 A ECSP088300 A EC SP088300A
Authority
EC
Ecuador
Prior art keywords
derivatives
treatment
conditions
combinations
retoma
Prior art date
Application number
EC2008008300A
Other languages
English (en)
Inventor
Puwen Zhang
Eugene Anthony Terefenko
An Thien Vu
Eugente John Trybulski
Casey Cameron Mccomas
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37684875&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP088300(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ECSP088300A publication Critical patent/ECSP088300A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se dirige a derivados benzotiadiazolilfenilalquilamina de la Fórmula I: o una sal farmacéuticamente aceptable de este, composiciones que contienen estos derivados, y los métodos de uso para la prevención y el tratamiento de condiciones de condiciones mejoradas por la retoma de monoamina que incluye, inter alia, síntomas vasomotores (VMS), disfunción sexual, trastornos gastrointestinales y genitourinarios, síndrome de fatiga crónica, síndrome de fibromialgia, trastornos del sistema nervioso central, y combinaciones de estos, particularmente aquellas condiciones seleccionadas del grupo que consiste de trastorno depresivo mayor, síntomas vasomotores, estrés e incontinencia urinaria alta, fibromialgia, dolor, neuropatía diabética, y combinaciones de este.
EC2008008300A 2005-09-29 2008-03-20 Derivados de benzotiadiazolilfenilalquilamina para uso en el tratamiento de condiciones mejoradas por la retoma de monoamina ECSP088300A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72169305P 2005-09-29 2005-09-29

Publications (1)

Publication Number Publication Date
ECSP088300A true ECSP088300A (es) 2008-04-28

Family

ID=37684875

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008300A ECSP088300A (es) 2005-09-29 2008-03-20 Derivados de benzotiadiazolilfenilalquilamina para uso en el tratamiento de condiciones mejoradas por la retoma de monoamina

Country Status (19)

Country Link
US (1) US7601744B2 (es)
EP (1) EP1934193A1 (es)
JP (1) JP2009510095A (es)
KR (1) KR20080050453A (es)
CN (1) CN101277941A (es)
AR (1) AR055660A1 (es)
AU (1) AU2006297208A1 (es)
BR (1) BRPI0616462A2 (es)
CA (1) CA2624096A1 (es)
CR (1) CR9829A (es)
EC (1) ECSP088300A (es)
GT (1) GT200600441A (es)
IL (1) IL190273A0 (es)
NO (1) NO20081235L (es)
PE (1) PE20070544A1 (es)
RU (1) RU2008110082A (es)
TW (1) TW200804325A (es)
WO (1) WO2007041258A1 (es)
ZA (1) ZA200802774B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2007003590A1 (es) 2006-12-12 2008-02-29 Wyeth Corp Compuestos derivados de aril sulfamida; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en prevencion y tratamiento de sintomas vasomotrices, disfuncion sexual, transtornos gastrointestinales, transt
US20090156826A1 (en) * 2007-12-12 2009-06-18 Wyeth Methods for the preparation of hydroxy-substituted aryl sulfamide compounds
CA2715192A1 (en) * 2008-02-19 2009-08-27 Adolor Corporation Beloxepin, its enantiomers, and analogs thereof for the treatment of pain
US20090233959A1 (en) 2008-02-19 2009-09-17 Adolor Corporation Beloxepin and analogs for the treatment of pain

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2321648A1 (en) 1998-03-02 1999-09-10 Hunter Heath Iii Fluoxetine hydrochloride for decreasing hot flashes
WO2004043903A1 (en) * 2002-11-05 2004-05-27 Eli Lilly And Company 3-aryloxy/ thio-2, 3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake
US7491723B2 (en) * 2003-10-14 2009-02-17 Wyeth Alkanol and cycloalkanol-amine derivatives and methods of their use

Also Published As

Publication number Publication date
JP2009510095A (ja) 2009-03-12
IL190273A0 (en) 2009-09-22
CA2624096A1 (en) 2007-04-12
TW200804325A (en) 2008-01-16
US20070072918A1 (en) 2007-03-29
US7601744B2 (en) 2009-10-13
NO20081235L (no) 2008-06-20
EP1934193A1 (en) 2008-06-25
BRPI0616462A2 (pt) 2011-06-21
WO2007041258A1 (en) 2007-04-12
PE20070544A1 (es) 2007-07-26
CN101277941A (zh) 2008-10-01
AR055660A1 (es) 2007-08-29
AU2006297208A1 (en) 2007-04-12
RU2008110082A (ru) 2009-11-10
GT200600441A (es) 2007-09-19
KR20080050453A (ko) 2008-06-05
ZA200802774B (en) 2009-01-28
CR9829A (es) 2008-04-28

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