ECSP088310A - Composición farmacéutica fotoestable que contiene brivudina para el tratamiento de la queratitis herpética - Google Patents

Composición farmacéutica fotoestable que contiene brivudina para el tratamiento de la queratitis herpética

Info

Publication number
ECSP088310A
ECSP088310A EC2008008310A ECSP088310A ECSP088310A EC SP088310 A ECSP088310 A EC SP088310A EC 2008008310 A EC2008008310 A EC 2008008310A EC SP088310 A ECSP088310 A EC SP088310A EC SP088310 A ECSP088310 A EC SP088310A
Authority
EC
Ecuador
Prior art keywords
treatment
brivudine
herpetetic
cheratitis
pharmaceutical composition
Prior art date
Application number
EC2008008310A
Other languages
English (en)
Inventor
Marc Wihsmann
Reinhard Schmitz
Original Assignee
Berlin Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berlin Chemie Ag filed Critical Berlin Chemie Ag
Publication of ECSP088310A publication Critical patent/ECSP088310A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Composiciones farmacéuticas que contienen el antiviral brivudina, útiles para el tratamiento de condiciones inflamatorias oculares, particularmente la queratitis estromal inducida por el Virus del Herpes Simple Tipo 1 (HSV-1) o por el Virus de la Varicela-Zóster (VZV). Las composiciones permiten la fotoprotección del antiviral con excelente tolerancia y administración prolongada de la brivudina.
EC2008008310A 2005-09-29 2008-03-25 Composición farmacéutica fotoestable que contiene brivudina para el tratamiento de la queratitis herpética ECSP088310A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005046769A DE102005046769A1 (de) 2005-09-29 2005-09-29 Lichtstabile, brivudinhaltige pharmazeutische Formulierung zur Behandlung von Augenherpes (Herpes Ophthalmicus)
PCT/EP2006/009383 WO2007039201A2 (en) 2005-09-29 2006-09-27 Photostable pharmaceutical composition containing brivudine for the treatment of herpetic keratitis

Publications (1)

Publication Number Publication Date
ECSP088310A true ECSP088310A (es) 2008-05-30

Family

ID=37561306

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008310A ECSP088310A (es) 2005-09-29 2008-03-25 Composición farmacéutica fotoestable que contiene brivudina para el tratamiento de la queratitis herpética

Country Status (33)

Country Link
US (1) US20080249061A1 (es)
EP (1) EP1940353B1 (es)
JP (1) JP2009509993A (es)
KR (1) KR20080053319A (es)
CN (1) CN101272765A (es)
AP (1) AP2008004394A0 (es)
AR (1) AR056551A1 (es)
AT (1) ATE489076T1 (es)
AU (1) AU2006299115A1 (es)
BR (1) BRPI0616449A2 (es)
CA (1) CA2624111A1 (es)
CR (1) CR9839A (es)
CY (1) CY1111059T1 (es)
DE (2) DE102005046769A1 (es)
DK (1) DK1940353T3 (es)
EA (1) EA012975B1 (es)
EC (1) ECSP088310A (es)
ES (1) ES2356774T3 (es)
HN (1) HN2008000497A (es)
HR (1) HRP20110085T1 (es)
IL (1) IL190466A0 (es)
MA (1) MA29887B1 (es)
NO (1) NO20081488L (es)
PE (1) PE20070767A1 (es)
PL (1) PL1940353T3 (es)
PT (1) PT1940353E (es)
RS (1) RS51615B (es)
SI (1) SI1940353T1 (es)
TN (1) TNSN08094A1 (es)
TW (1) TW200744664A (es)
UA (1) UA90911C2 (es)
WO (1) WO2007039201A2 (es)
ZA (1) ZA200802729B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009006130A2 (en) * 2007-06-28 2009-01-08 Bausch & Lomb Incorporated Salt free hyaluronate ophthalmic solution
US20090196833A1 (en) * 2008-02-06 2009-08-06 Adherex Technologies Inc. Compositions comprising topical dpd inhibitors and methods of using same in the treatment of hand-foot syndrome
DE102009003942A1 (de) * 2009-01-07 2010-07-08 D2O Biosience Group Ltd., Hamilton Verwendung von Deuteriumoxid zur Behandlung Virus-basierter Erkrankungen des Auges
PT2898888T (pt) 2014-01-22 2019-07-16 Visufarma B V Composição que compreende iota-carragenina contra conjuntivite viral
JP6941157B2 (ja) * 2016-05-06 2021-09-29 サックシュ・コーポレーション 眼科用組成物
CN113712928A (zh) * 2021-09-29 2021-11-30 重庆市力扬医药开发有限公司 经口腔粘膜吸收的溴夫定药物
EP4623919A1 (en) 2024-03-28 2025-10-01 Marinomed Biotech AG Composition comprising iota-carrageenan for the treatment of dry eyes, non-viral conjunctivitis and allergic ocular conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY136633A (en) * 2001-01-17 2008-11-28 Berlin Chemie Ag Stabilized brivudine topical formulations
DE10162593A1 (de) * 2001-12-19 2003-07-03 Menarini Ricerche Spa Stabilisierte topische Brivudin-Formulierungen

Also Published As

Publication number Publication date
ES2356774T3 (es) 2011-04-13
AU2006299115A2 (en) 2008-05-29
CN101272765A (zh) 2008-09-24
KR20080053319A (ko) 2008-06-12
HN2008000497A (es) 2010-09-10
CY1111059T1 (el) 2015-06-11
WO2007039201A2 (en) 2007-04-12
DE102005046769A1 (de) 2007-04-05
ATE489076T1 (de) 2010-12-15
TNSN08094A1 (en) 2009-07-14
TW200744664A (en) 2007-12-16
PL1940353T3 (pl) 2011-05-31
AR056551A1 (es) 2007-10-10
AU2006299115A1 (en) 2007-04-12
UA90911C2 (ru) 2010-06-10
US20080249061A1 (en) 2008-10-09
PE20070767A1 (es) 2007-08-13
SI1940353T1 (sl) 2011-03-31
WO2007039201A3 (en) 2007-10-04
HRP20110085T1 (hr) 2011-03-31
DK1940353T3 (da) 2011-01-24
ZA200802729B (en) 2009-09-30
CA2624111A1 (en) 2007-04-12
NO20081488L (no) 2008-03-26
JP2009509993A (ja) 2009-03-12
EA012975B1 (ru) 2010-02-26
EP1940353A2 (en) 2008-07-09
EA200800646A1 (ru) 2008-10-30
AP2008004394A0 (en) 2008-04-30
CR9839A (es) 2008-10-31
EP1940353B1 (en) 2010-11-24
RS51615B (sr) 2011-08-31
BRPI0616449A2 (pt) 2011-06-21
DE602006018505D1 (de) 2011-01-05
MA29887B1 (fr) 2008-10-03
IL190466A0 (en) 2008-11-03
PT1940353E (pt) 2011-02-25

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