BRPI0414062B8 - uso de ciclosporinas modificadas para o tratamento de distúrbios por hcv - Google Patents

uso de ciclosporinas modificadas para o tratamento de distúrbios por hcv

Info

Publication number
BRPI0414062B8
BRPI0414062B8 BRPI0414062A BRPI0414062A BRPI0414062B8 BR PI0414062 B8 BRPI0414062 B8 BR PI0414062B8 BR PI0414062 A BRPI0414062 A BR PI0414062A BR PI0414062 A BRPI0414062 A BR PI0414062A BR PI0414062 B8 BRPI0414062 B8 BR PI0414062B8
Authority
BR
Brazil
Prior art keywords
treatment
cyclosporins
modified
hcv
disorders
Prior art date
Application number
BRPI0414062A
Other languages
English (en)
Inventor
Watashi Koichi
Shimotohno Kunitada
Hijikata Makoto
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0414062A publication Critical patent/BRPI0414062A/pt
Publication of BRPI0414062B1 publication Critical patent/BRPI0414062B1/pt
Publication of BRPI0414062B8 publication Critical patent/BRPI0414062B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

uso de ciclosporinas modificadas para o tratamento de distúrbios por hcv. a presente invenção refere-se a ciclosporinas de ligação à ciclofilina não-imunossupressoras, por exemplo, de fórmula (i, ia ou ii), conforme aqui definida, com propriedades úteis na prevenção ou tratamento de infecções de hepatite c.
BRPI0414062A 2003-09-03 2004-09-02 uso de ciclosporinas modificadas para o tratamento de distúrbios por hcv BRPI0414062B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0320638.0 2003-09-03
GBGB0320638.0A GB0320638D0 (en) 2003-09-03 2003-09-03 Organic compounds
PCT/EP2004/009804 WO2005021028A1 (en) 2003-09-03 2004-09-02 Use of modified cyclosporins for the treatment of hcv disorders

Publications (3)

Publication Number Publication Date
BRPI0414062A BRPI0414062A (pt) 2006-10-24
BRPI0414062B1 BRPI0414062B1 (pt) 2019-06-25
BRPI0414062B8 true BRPI0414062B8 (pt) 2021-05-25

Family

ID=28686843

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414062A BRPI0414062B8 (pt) 2003-09-03 2004-09-02 uso de ciclosporinas modificadas para o tratamento de distúrbios por hcv

Country Status (29)

Country Link
US (1) US7968518B2 (pt)
EP (2) EP1797892B1 (pt)
JP (1) JP4688806B2 (pt)
KR (1) KR101116968B1 (pt)
CN (1) CN1842343A (pt)
AU (2) AU2004268382A1 (pt)
BR (1) BRPI0414062B8 (pt)
CA (1) CA2537137C (pt)
CY (1) CY1110506T1 (pt)
DE (1) DE602004022061D1 (pt)
DK (1) DK1663287T3 (pt)
ES (1) ES2328361T3 (pt)
GB (1) GB0320638D0 (pt)
HR (1) HRP20090535T1 (pt)
IL (1) IL173909A (pt)
IS (1) IS2917B (pt)
MA (1) MA28032A1 (pt)
MX (1) MXPA06002394A (pt)
NO (1) NO20061479L (pt)
NZ (1) NZ545495A (pt)
PL (1) PL1663287T3 (pt)
PT (1) PT1663287E (pt)
RU (1) RU2389501C2 (pt)
SG (1) SG149063A1 (pt)
SI (1) SI1663287T1 (pt)
TN (1) TNSN06071A1 (pt)
TW (1) TWI342782B (pt)
WO (1) WO2005021028A1 (pt)
ZA (1) ZA200601550B (pt)

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Also Published As

Publication number Publication date
PL1663287T3 (pl) 2009-12-31
EP1663287A1 (en) 2006-06-07
TNSN06071A1 (en) 2007-10-03
TWI342782B (en) 2011-06-01
IL173909A0 (en) 2006-07-05
IL173909A (en) 2011-03-31
PT1663287E (pt) 2009-09-03
AU2008203031B2 (en) 2011-04-07
IS2917B (is) 2014-12-15
US20070275884A1 (en) 2007-11-29
DE602004022061D1 (de) 2009-08-27
IS8371A (is) 2006-03-24
ES2328361T3 (es) 2009-11-12
KR101116968B1 (ko) 2012-03-14
AU2008203031A1 (en) 2008-07-31
JP2007504260A (ja) 2007-03-01
MXPA06002394A (es) 2006-06-20
NZ545495A (en) 2010-01-29
BRPI0414062A (pt) 2006-10-24
HK1091732A1 (en) 2007-01-26
KR20060132798A (ko) 2006-12-22
EP1797892A1 (en) 2007-06-20
TW200524626A (en) 2005-08-01
DK1663287T3 (da) 2009-11-09
NO20061479L (no) 2006-06-02
RU2006110533A (ru) 2007-10-10
RU2389501C2 (ru) 2010-05-20
ZA200601550B (en) 2007-05-30
CA2537137C (en) 2013-05-28
BRPI0414062B1 (pt) 2019-06-25
GB0320638D0 (en) 2003-10-01
AU2004268382A1 (en) 2005-03-10
JP4688806B2 (ja) 2011-05-25
CN1842343A (zh) 2006-10-04
SI1663287T1 (sl) 2009-10-31
CA2537137A1 (en) 2005-03-10
HRP20090535T1 (hr) 2009-11-30
SG149063A1 (en) 2009-01-29
US7968518B2 (en) 2011-06-28
CY1110506T1 (el) 2015-04-29
EP1663287B1 (en) 2009-07-15
EP1797892B1 (en) 2013-10-23
WO2005021028A1 (en) 2005-03-10
MA28032A1 (fr) 2006-07-03

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