ECSP088634A - Metodos para tratar infecciones del tracto gastrointestinal con tigeciclina - Google Patents
Metodos para tratar infecciones del tracto gastrointestinal con tigeciclinaInfo
- Publication number
- ECSP088634A ECSP088634A EC2008008634A ECSP088634A ECSP088634A EC SP088634 A ECSP088634 A EC SP088634A EC 2008008634 A EC2008008634 A EC 2008008634A EC SP088634 A ECSP088634 A EC SP088634A EC SP088634 A ECSP088634 A EC SP088634A
- Authority
- EC
- Ecuador
- Prior art keywords
- methods
- tigecicline
- gastrointestinal tract
- tract infections
- treat gastrointestinal
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 210000001035 gastrointestinal tract Anatomy 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 239000007787 solid Substances 0.000 abstract 2
- FPZLLRFZJZRHSY-HJYUBDRYSA-N tigecycline Chemical compound C([C@H]1C2)C3=C(N(C)C)C=C(NC(=O)CNC(C)(C)C)C(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2[C@H](N(C)C)C(O)=C(C(N)=O)C1=O FPZLLRFZJZRHSY-HJYUBDRYSA-N 0.000 abstract 2
- 229960004089 tigecycline Drugs 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 206010017964 Gastrointestinal infection Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000002702 enteric coating Substances 0.000 abstract 1
- 238000009505 enteric coating Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
En la presente se describen métodos para tratar al menos una infección bacteriana, tal como infecciones gastrointestinales inferiores, que comprenden administrar oralmente una composición farmacéutica que comprende tigeciclina. La composición puede tomar formas sólidas o líquidas, tal como soluciones, dispersiones o formas sólidas que comprenden tigeciclina que tiene al menos un revestimiento entérico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75316105P | 2005-12-22 | 2005-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP088634A true ECSP088634A (es) | 2008-08-29 |
Family
ID=37963595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2008008634A ECSP088634A (es) | 2005-12-22 | 2008-07-18 | Metodos para tratar infecciones del tracto gastrointestinal con tigeciclina |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20070243244A1 (es) |
| EP (1) | EP1962860A1 (es) |
| JP (1) | JP2009521456A (es) |
| KR (1) | KR20080085184A (es) |
| CN (1) | CN101340917A (es) |
| AU (1) | AU2006331685A1 (es) |
| BR (1) | BRPI0620430A2 (es) |
| CA (1) | CA2631632A1 (es) |
| CR (1) | CR10023A (es) |
| EC (1) | ECSP088634A (es) |
| GT (1) | GT200800115A (es) |
| IL (1) | IL191598A0 (es) |
| NO (1) | NO20082396L (es) |
| RU (1) | RU2008121238A (es) |
| WO (1) | WO2007075792A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080005599A (ko) * | 2005-05-06 | 2008-01-14 | 와이어쓰 | 헤파린 존재하에 티게사이클린의 전달 |
| WO2009143150A2 (en) * | 2008-05-19 | 2009-11-26 | Burnham Institute For Medical Research | Intestinal alkaline phosphatase modulators and uses thereof |
| MX347919B (es) | 2010-05-12 | 2017-05-17 | Rempex Pharmaceuticals Inc * | Composiciones de tetraciclina. |
| CN103356662B (zh) * | 2012-03-27 | 2015-11-25 | 浙江医药股份有限公司新昌制药厂 | 注射用替加环素组合物及其制备方法 |
| CN103263400B (zh) * | 2013-01-16 | 2014-12-17 | 内蒙古金河动物药业有限公司 | 一种金霉素微囊制剂及其制备方法 |
| US9457086B2 (en) * | 2013-03-05 | 2016-10-04 | Enteris Biopharma, Inc. | Pharmaceuticals for oral delivery |
| CA2973099C (en) | 2015-01-12 | 2021-09-14 | Enteris Biopharma, Inc. | Solid oral dosage forms |
| CN119454720A (zh) * | 2016-03-24 | 2025-02-18 | 帕拉特克Spv2有限责任公司 | 用于治疗和预防艰难梭菌感染的方法 |
| CN111166729A (zh) * | 2020-03-19 | 2020-05-19 | 珠海赛隆药业股份有限公司 | 一种口服的替加环素肠溶微球及其制备方法 |
| CN112843071A (zh) * | 2020-09-08 | 2021-05-28 | 天津国际生物医药联合研究院 | 土霉素或者替加环素在抗分枝杆菌感染中的潜在应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3026248A (en) * | 1959-09-11 | 1962-03-20 | Pfizer & Co C | Thioglycerol and formaldehyde sulfoxylate stabilized tetracycline antibiotics in polyhydric alcohol solvents |
| US3219529A (en) * | 1962-10-04 | 1965-11-23 | American Cyanamid Co | Stable tetracycline solutions |
| US5281628A (en) * | 1991-10-04 | 1994-01-25 | American Cyanamid Company | 9-amino-7-(substituted)-6-demethyl-6-deoxytetracyclines |
| US5494903A (en) * | 1991-10-04 | 1996-02-27 | American Cyanamid Company | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
| US5167964A (en) * | 1992-02-14 | 1992-12-01 | Warner-Lambert Company | Semi-enteric drug delivery systems and methods for preparing same |
| US5284963A (en) * | 1992-08-13 | 1994-02-08 | American Cyanamid Company | Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines |
| US5328902A (en) * | 1992-08-13 | 1994-07-12 | American Cyanamid Co. | 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
| SG47520A1 (en) * | 1992-08-13 | 1998-04-17 | American Cyanamid Co | New method for the production of 9-amino-6-demethyl-6-deoxytetracycline |
| US5420272A (en) * | 1992-08-13 | 1995-05-30 | American Cyanamid Company | 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
| WO1995022529A1 (en) * | 1994-02-17 | 1995-08-24 | Pfizer Inc. | 9-(substituted amino)-alpha-6-deoxy-5-oxy tetracycline derivatives, their preparation and their use as antibiotics |
| US5675030A (en) * | 1994-11-16 | 1997-10-07 | American Cyanamid Company | Method for selective extracting a 7-(hydrogen or substituted amino)-9- (substituted glycyl) amido!-6-demethyl-6-deoxytetracycline compound |
| US5567693A (en) * | 1994-12-13 | 1996-10-22 | American Cyanamid Company | Method for inhibiting angiogenesis, proliferation of endothelial or tumor cells and tumor growth |
| US6063775A (en) * | 1997-04-29 | 2000-05-16 | Berman; Charles L. | Retardation of metalloproteinase incidental to HIV and/or AIDS |
| US5908838A (en) * | 1998-02-19 | 1999-06-01 | Medics Pharmaceutical Corporation | Method for the treatment of acne |
| US6015803A (en) * | 1998-05-04 | 2000-01-18 | Wirostko; Emil | Antibiotic treatment of age-related macular degeneration |
| US6015804A (en) * | 1998-09-11 | 2000-01-18 | The Research Foundation Of State University Of New York | Method of using tetracycline compounds to enhance interleukin-10 production |
| US5998390A (en) * | 1998-09-28 | 1999-12-07 | The Research Foundation Of State University Of New York | Combination of bisphosphonate and tetracycline |
| US6506740B1 (en) * | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
| US20040131628A1 (en) * | 2000-03-08 | 2004-07-08 | Bratzler Robert L. | Nucleic acids for the treatment of disorders associated with microorganisms |
| ATE365710T1 (de) * | 2000-03-31 | 2007-07-15 | Tufts College | 7- und 9-carbamat, harnstoff, thioharnstoff, thiocarbamat und heteroaryl-amino substituierte tetracyclinverbindungen |
| BR0112265A (pt) * | 2000-07-07 | 2003-06-24 | Tufts College | Compostos de tetraciclina substituìda, e de sanciclina 7-substituìda, método para tratar um estado responsivo à tetraciclina em um indivìduo, e, composição farmacêutica |
| CZ2003344A3 (cs) * | 2000-07-07 | 2003-05-14 | Trustees Of Tufts College | 9-Substituované minocyklinové sloučeniny |
| WO2002072532A1 (en) * | 2001-03-13 | 2002-09-19 | Paratek Pharmaceuticals, Inc. | 7, 9-substituted tetracycline compounds |
| US6841546B2 (en) * | 2001-03-14 | 2005-01-11 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds as antifungal agents |
| EP1408987B1 (en) * | 2001-07-13 | 2013-04-10 | Paratek Pharmaceuticals, Inc. | Tetracycline compounds having target therapeutic activities |
| EP2311797A1 (en) * | 2002-01-08 | 2011-04-20 | Paratek Pharmaceuticals, Inc. | 4-dedimethylamino tetracycline compounds |
| US6958161B2 (en) * | 2002-04-12 | 2005-10-25 | F H Faulding & Co Limited | Modified release coated drug preparation |
| WO2004006850A2 (en) * | 2002-07-12 | 2004-01-22 | Paratek Pharmaceuticals, Inc | 3, 10, AND 12a SUBSTITUTED TETRACYCLINE COMPOUNDS |
| WO2004017925A2 (en) * | 2002-08-23 | 2004-03-04 | Genome Therapeutics Corporation | Methods and reagents for preventing bacteremias |
| ATE448775T1 (de) * | 2002-08-29 | 2009-12-15 | Activbiotics Pharma Llc | Rifalazil zur behandlung von infektionen mit clostridium difficile |
| US20050148553A1 (en) * | 2003-09-05 | 2005-07-07 | Testa Raymond T. | Use of tigecycline, alone, or in combination with rifampin to treat osteomyelitis and/or septic arthritis |
-
2006
- 2006-12-20 WO PCT/US2006/048617 patent/WO2007075792A1/en not_active Ceased
- 2006-12-20 RU RU2008121238/14A patent/RU2008121238A/ru not_active Application Discontinuation
- 2006-12-20 CN CNA2006800477777A patent/CN101340917A/zh active Pending
- 2006-12-20 EP EP06847831A patent/EP1962860A1/en not_active Withdrawn
- 2006-12-20 CA CA002631632A patent/CA2631632A1/en not_active Abandoned
- 2006-12-20 JP JP2008547492A patent/JP2009521456A/ja active Pending
- 2006-12-20 KR KR1020087017967A patent/KR20080085184A/ko not_active Withdrawn
- 2006-12-20 BR BRPI0620430-9A patent/BRPI0620430A2/pt not_active Application Discontinuation
- 2006-12-20 AU AU2006331685A patent/AU2006331685A1/en not_active Abandoned
- 2006-12-21 US US11/642,522 patent/US20070243244A1/en not_active Abandoned
-
2008
- 2008-05-21 IL IL191598A patent/IL191598A0/en unknown
- 2008-05-27 CR CR10023A patent/CR10023A/es not_active Application Discontinuation
- 2008-05-27 NO NO20082396A patent/NO20082396L/no not_active Application Discontinuation
- 2008-06-19 GT GT200800115A patent/GT200800115A/es unknown
- 2008-07-18 EC EC2008008634A patent/ECSP088634A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL191598A0 (en) | 2009-08-03 |
| CR10023A (es) | 2008-08-21 |
| CN101340917A (zh) | 2009-01-07 |
| AU2006331685A1 (en) | 2007-07-05 |
| NO20082396L (no) | 2008-08-26 |
| EP1962860A1 (en) | 2008-09-03 |
| WO2007075792A1 (en) | 2007-07-05 |
| KR20080085184A (ko) | 2008-09-23 |
| GT200800115A (es) | 2009-01-16 |
| US20070243244A1 (en) | 2007-10-18 |
| RU2008121238A (ru) | 2010-01-27 |
| BRPI0620430A2 (pt) | 2011-11-08 |
| JP2009521456A (ja) | 2009-06-04 |
| CA2631632A1 (en) | 2007-07-05 |
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