ECSP088662A - AGENTE TERAPÉUTICO PARA ENFERMEDAD INTESTINAL INFLAMATORIA QUE CONTIENE COMO UN INGREDIENTE ACTIVO UN DERIVADO DE 2-AMINO-l, 3-PROPANEDIOL O MÉTODO PARA TRATAR ENFERMEDAD INTESTINAL INFLAMATORIA - Google Patents
AGENTE TERAPÉUTICO PARA ENFERMEDAD INTESTINAL INFLAMATORIA QUE CONTIENE COMO UN INGREDIENTE ACTIVO UN DERIVADO DE 2-AMINO-l, 3-PROPANEDIOL O MÉTODO PARA TRATAR ENFERMEDAD INTESTINAL INFLAMATORIAInfo
- Publication number
- ECSP088662A ECSP088662A EC2008008662A ECSP088662A ECSP088662A EC SP088662 A ECSP088662 A EC SP088662A EC 2008008662 A EC2008008662 A EC 2008008662A EC SP088662 A ECSP088662 A EC SP088662A EC SP088662 A ECSP088662 A EC SP088662A
- Authority
- EC
- Ecuador
- Prior art keywords
- intestinal disease
- inflammatory intestinal
- amino
- propanediol
- derivative
- Prior art date
Links
- 208000028774 intestinal disease Diseases 0.000 title abstract 3
- 230000002757 inflammatory effect Effects 0.000 title 2
- 239000004480 active ingredient Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 208000011231 Crohn disease Diseases 0.000 abstract 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- KJJPLEZQSCZCKE-UHFFFAOYSA-N 2-aminopropane-1,3-diol Chemical class OCC(N)CO KJJPLEZQSCZCKE-UHFFFAOYSA-N 0.000 abstract 1
- -1 3-benzyloxyphenylthio Chemical group 0.000 abstract 1
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 1
- 208000002389 Pouchitis Diseases 0.000 abstract 1
- 206010038063 Rectal haemorrhage Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 1
- 210000002429 large intestine Anatomy 0.000 abstract 1
- JTMVQBIJMXSDDD-UHFFFAOYSA-N pentane-1,3-diol hydrochloride Chemical compound Cl.CCC(O)CCO JTMVQBIJMXSDDD-UHFFFAOYSA-N 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un agente terapéutico y profiláctico nuevo para enfermedades inflamatorias intestinales y un método para tratar enfermedades intestinales inflamatorias.El agente comprende un derivado de 2-amino-l,3-propanediol (por ejemplo 2-amino-2-[4-(3-benziloxifeniltio)-2-clorofenilo]etilo-1,3 clorhidrato de propanediol) representado por la formula química (1) o una sal farmacéuticamente aceptable o hidrato de está: (Fórmula química 1) (1)El agente es útil en el tratamiento o prevención de la enfermedad de Crohn, la enfermedad de Crohn en el intestino grueso, la enfermedad intestinal de Behcet, ulcerativa colitis, úlcera rectal sangrante y pouchitis.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006027883 | 2006-02-06 | ||
| PCT/JP2007/051887 WO2007091501A1 (ja) | 2006-02-06 | 2007-02-05 | 2-アミノ-1,3-プロパンジオール誘導体を有効成分とする炎症性腸疾患治療剤又は炎症性腸疾患の治療方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP088662A true ECSP088662A (es) | 2008-09-29 |
Family
ID=38345101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2008008662A ECSP088662A (es) | 2006-02-06 | 2008-08-05 | AGENTE TERAPÉUTICO PARA ENFERMEDAD INTESTINAL INFLAMATORIA QUE CONTIENE COMO UN INGREDIENTE ACTIVO UN DERIVADO DE 2-AMINO-l, 3-PROPANEDIOL O MÉTODO PARA TRATAR ENFERMEDAD INTESTINAL INFLAMATORIA |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8318811B2 (es) |
| EP (2) | EP2520291A1 (es) |
| JP (1) | JP5042042B2 (es) |
| KR (1) | KR101334153B1 (es) |
| CN (1) | CN101378743B (es) |
| AU (1) | AU2007213194B9 (es) |
| BR (1) | BRPI0706971A2 (es) |
| CA (1) | CA2641546C (es) |
| CY (1) | CY1116112T1 (es) |
| DK (1) | DK1982708T3 (es) |
| EC (1) | ECSP088662A (es) |
| ES (1) | ES2524056T3 (es) |
| GT (1) | GT200800148A (es) |
| HR (1) | HRP20080421B1 (es) |
| IL (1) | IL192150A (es) |
| MA (1) | MA31338B1 (es) |
| MX (1) | MX2008008872A (es) |
| MY (1) | MY151193A (es) |
| NO (1) | NO20082708L (es) |
| NZ (1) | NZ568907A (es) |
| PL (1) | PL1982708T3 (es) |
| PT (1) | PT1982708E (es) |
| RU (1) | RU2428976C2 (es) |
| SG (1) | SG169370A1 (es) |
| SI (1) | SI1982708T1 (es) |
| TN (1) | TNSN08246A1 (es) |
| TW (1) | TWI389683B (es) |
| WO (1) | WO2007091501A1 (es) |
| ZA (1) | ZA200806199B (es) |
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| PT1932522E (pt) | 2005-10-07 | 2012-06-26 | Kyorin Seiyaku Kk | Agente terapêutico para doenças do fígado contendo, como princípio activo, um derivado de 2- amino-1,3-propanodiol |
| TWI389683B (zh) | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| MY146775A (en) | 2006-08-08 | 2012-09-28 | Kyorin Seiyaku Kk | Amino alcohol derivative and immunosuppressive agent having same as an active ingredient |
| SG174028A1 (en) | 2006-08-08 | 2011-09-29 | Kyorin Seiyaku Kk | Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient |
| US8476305B2 (en) | 2008-02-07 | 2013-07-02 | Kyorin Pharmaceutical Co., Ltd. | Therapeutic agent or prophylactic agent for inflammatory bowel disease comprising amino alcohol derivative as active ingredient |
| NZ589412A (en) * | 2008-05-20 | 2012-11-30 | Kyorin Seiyaku Kk | Use of a sphingosine-1-phosphate (S1P) agonist for maintance of induced remission of autoimmune or inflammatory diseases after inital treatment |
| KR20190004843A (ko) | 2008-07-23 | 2019-01-14 | 아레나 파마슈티칼스, 인크. | 자가면역성 및 염증성의 장애의 치료에 유용한 치환된 1,2,3,4-테트라히드로시클로펜타[b]인돌-3-일)아세트산 유도체 |
| JP5726737B2 (ja) * | 2008-08-27 | 2015-06-03 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 自己免疫障害および免疫性障害の治療において有用なs1p1受容体のアゴニストとしての置換三環式酸誘導体 |
| EP2177521A1 (en) * | 2008-10-14 | 2010-04-21 | Almirall, S.A. | New 2-Amidothiadiazole Derivatives |
| EP2364088B1 (en) * | 2008-10-30 | 2014-04-16 | Biogen Idec MA Inc. | Bicyclic aryl sphingosine 1-phosphate analogs |
| EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
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| EP2305660A1 (en) | 2009-09-25 | 2011-04-06 | Almirall, S.A. | New thiadiazole derivatives |
| EP2343287A1 (en) | 2009-12-10 | 2011-07-13 | Almirall, S.A. | New 2-aminothiadiazole derivatives |
| CN108558740B (zh) | 2010-01-27 | 2021-10-19 | 艾尼纳制药公司 | S1p1受体调节剂及其盐的制备方法 |
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| AR085749A1 (es) | 2011-04-01 | 2013-10-23 | Novartis Ag | Formulaciones |
| KR101787543B1 (ko) | 2014-08-22 | 2017-10-19 | 샘표식품 주식회사 | 발효배양 산삼을 포함하는 항염증 조성물 |
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2007
- 2007-01-25 TW TW096102882A patent/TWI389683B/zh not_active IP Right Cessation
- 2007-02-05 SI SI200731574T patent/SI1982708T1/sl unknown
- 2007-02-05 EP EP12167430A patent/EP2520291A1/en not_active Withdrawn
- 2007-02-05 MY MYPI20082159 patent/MY151193A/en unknown
- 2007-02-05 US US12/223,584 patent/US8318811B2/en active Active
- 2007-02-05 EP EP07713815.4A patent/EP1982708B1/en active Active
- 2007-02-05 BR BRPI0706971-5A patent/BRPI0706971A2/pt not_active IP Right Cessation
- 2007-02-05 DK DK07713815.4T patent/DK1982708T3/en active
- 2007-02-05 HR HRP20080421AA patent/HRP20080421B1/hr not_active IP Right Cessation
- 2007-02-05 RU RU2008135264/15A patent/RU2428976C2/ru not_active IP Right Cessation
- 2007-02-05 PT PT77138154T patent/PT1982708E/pt unknown
- 2007-02-05 NZ NZ568907A patent/NZ568907A/en not_active IP Right Cessation
- 2007-02-05 JP JP2007557819A patent/JP5042042B2/ja not_active Expired - Fee Related
- 2007-02-05 KR KR1020087017968A patent/KR101334153B1/ko not_active Expired - Fee Related
- 2007-02-05 CN CN200780004468.6A patent/CN101378743B/zh not_active Expired - Fee Related
- 2007-02-05 CA CA2641546A patent/CA2641546C/en not_active Expired - Fee Related
- 2007-02-05 MX MX2008008872A patent/MX2008008872A/es active IP Right Grant
- 2007-02-05 AU AU2007213194A patent/AU2007213194B9/en not_active Ceased
- 2007-02-05 PL PL07713815T patent/PL1982708T3/pl unknown
- 2007-02-05 WO PCT/JP2007/051887 patent/WO2007091501A1/ja not_active Ceased
- 2007-02-05 SG SG201100761-4A patent/SG169370A1/en unknown
- 2007-02-05 ES ES07713815.4T patent/ES2524056T3/es active Active
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2008
- 2008-06-06 TN TNP2008000246A patent/TNSN08246A1/en unknown
- 2008-06-12 IL IL192150A patent/IL192150A/en not_active IP Right Cessation
- 2008-06-12 NO NO20082708A patent/NO20082708L/no not_active Application Discontinuation
- 2008-07-16 ZA ZA200806199A patent/ZA200806199B/xx unknown
- 2008-07-25 GT GT200800148A patent/GT200800148A/es unknown
- 2008-08-05 EC EC2008008662A patent/ECSP088662A/es unknown
- 2008-08-26 MA MA31196A patent/MA31338B1/fr unknown
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2015
- 2015-01-26 CY CY20151100081T patent/CY1116112T1/el unknown
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