ECSP099045A - Sal xinafoato de un compuesto de 5-oxazol-2-il-quinolina sustituido - Google Patents

Sal xinafoato de un compuesto de 5-oxazol-2-il-quinolina sustituido

Info

Publication number
ECSP099045A
ECSP099045A EC2009009045A ECSP099045A ECSP099045A EC SP099045 A ECSP099045 A EC SP099045A EC 2009009045 A EC2009009045 A EC 2009009045A EC SP099045 A ECSP099045 A EC SP099045A EC SP099045 A ECSP099045 A EC SP099045A
Authority
EC
Ecuador
Prior art keywords
oxazol
substituted
quinoline compound
xinafoate salt
compound
Prior art date
Application number
EC2009009045A
Other languages
English (en)
Inventor
Michael R Reeder
Pauline C Ting
Joe F Lee
Kung I Feng
Scott T Trzaska
Man Zhu
Chen Mao
Dimitar L Filipov
Dimitrios Zarkadas
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ECSP099045A publication Critical patent/ECSP099045A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La presente invención se refiere al compuesto de fórmula ,a métodos para tratar enfermedades obstructivas de las vías aéreas superiores e inferiores utilizando dicho compuesto, a formulaciones que lo comprende, y a polimorfos y procesos de síntesis de las formas polimórficas.
EC2009009045A 2006-07-11 2009-01-09 Sal xinafoato de un compuesto de 5-oxazol-2-il-quinolina sustituido ECSP099045A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83005706P 2006-07-11 2006-07-11

Publications (1)

Publication Number Publication Date
ECSP099045A true ECSP099045A (es) 2009-02-27

Family

ID=38895717

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009045A ECSP099045A (es) 2006-07-11 2009-01-09 Sal xinafoato de un compuesto de 5-oxazol-2-il-quinolina sustituido

Country Status (22)

Country Link
US (1) US7919505B2 (es)
EP (1) EP2038277A2 (es)
JP (2) JP5097774B2 (es)
KR (1) KR20090026217A (es)
CN (1) CN101547920B (es)
AR (1) AR061890A1 (es)
AU (1) AU2007273007B2 (es)
BR (1) BRPI0712915A2 (es)
CA (1) CA2657902A1 (es)
CL (1) CL2007002020A1 (es)
CO (1) CO6190533A2 (es)
EC (1) ECSP099045A (es)
IL (1) IL196402A0 (es)
MX (1) MX2009000460A (es)
NO (1) NO20090646L (es)
NZ (1) NZ574070A (es)
PE (2) PE20080550A1 (es)
RU (1) RU2009104346A (es)
SG (1) SG173366A1 (es)
TW (1) TW200813040A (es)
WO (1) WO2008008327A2 (es)
ZA (1) ZA200900208B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE531705T1 (de) * 2004-05-18 2011-11-15 Schering Corp Substituierte 2-chinolyloxazole geeignet als pde4 inhibitoren
AU2007284688A1 (en) * 2006-08-14 2008-02-21 Schering Corporation Process and intermediates for the synthesis of 2-(Quinolin-5-yl)-4,5 Disubstituted-Azole derivatives
US20100324295A1 (en) * 2007-07-10 2010-12-23 Schering Corporation Process for the production of substituted 5-quinolyl-oxazoles and pharmaceutically acceptable salts thereof
EP2176257A2 (en) * 2007-07-10 2010-04-21 Schering Corporation Hydrogen chloride salt of a substituted 5-oxazol-2-yl-quinoline compound and a process for the production thereof
JP5709101B2 (ja) * 2010-09-01 2015-04-30 東レ・ファインケミカル株式会社 ヒドロキシプロリン誘導体の製造法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2600644B2 (ja) 1991-08-16 1997-04-16 藤沢薬品工業株式会社 チアゾリルベンゾフラン誘導体
US5352707A (en) 1992-03-26 1994-10-04 Harbor Branch Oceanographic Institution, Inc. Method for treating airway congestion
US5270324A (en) 1992-04-10 1993-12-14 Merck Frosst Canada, Inc. Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists
US5472964A (en) 1992-12-22 1995-12-05 Merck Frosst Canada, Inc. Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists
JP2000510866A (ja) 1996-05-20 2000-08-22 ダーウィン・ディスカバリー・リミテッド Ｔｎｆとｐｄｅ―ｉｖのインヒビターとしてのキノリンスルホンアミド
NZ332341A (en) 1996-05-20 2000-05-26 Darwin Discovery Ltd Quinoline carboxamides as TNF inhibitors and as PDE-IV inhibitors
US6069151A (en) 1996-11-06 2000-05-30 Darwin Discovery, Ltd. Quinolines and their therapeutic use
US20050017134A1 (en) 2003-07-24 2005-01-27 Hooper Patricia E. Glass and bottle holders
ATE531705T1 (de) * 2004-05-18 2011-11-15 Schering Corp Substituierte 2-chinolyloxazole geeignet als pde4 inhibitoren
EP2484382A1 (en) 2005-03-30 2012-08-08 Schering Corporation Medicament comprising a phosphodiesterase IV inhibitor in an inhalable form

Also Published As

Publication number Publication date
TW200813040A (en) 2008-03-16
CN101547920A (zh) 2009-09-30
JP2012214482A (ja) 2012-11-08
MX2009000460A (es) 2009-01-27
BRPI0712915A2 (pt) 2012-10-09
WO2008008327A2 (en) 2008-01-17
WO2008008327A3 (en) 2008-03-06
AU2007273007A1 (en) 2008-01-17
SG173366A1 (en) 2011-08-29
CO6190533A2 (es) 2010-08-19
NO20090646L (no) 2009-04-07
PE20110391A1 (es) 2011-06-22
CL2007002020A1 (es) 2008-02-22
CN101547920B (zh) 2012-06-27
CA2657902A1 (en) 2008-01-17
AR061890A1 (es) 2008-10-01
US20080027101A1 (en) 2008-01-31
JP2009542811A (ja) 2009-12-03
US7919505B2 (en) 2011-04-05
ZA200900208B (en) 2010-01-27
AU2007273007B2 (en) 2012-11-01
EP2038277A2 (en) 2009-03-25
PE20080550A1 (es) 2008-06-13
IL196402A0 (en) 2009-09-22
NZ574070A (en) 2011-12-22
RU2009104346A (ru) 2010-08-20
KR20090026217A (ko) 2009-03-11
JP5097774B2 (ja) 2012-12-12

Similar Documents

Publication Publication Date Title
BRPI0520870B8 (pt) compostos intermediários para a preparação de alfa-mercaptoacetanilidas de s-triazolila
BRPI0817909A2 (pt) Intermediários e métodos para a síntese de análogos de halicondrina
ES2380489T8 (es) Proceso para la síntesis de compuestos orgánicos
CL2008000322A1 (es) Proceso para la preparacion de un compuesto derivado de 2-tiazol-2-il-quinolina; compuestos intermediarios; y proceso de preparacion de dichos compuestos intermediarios.
BRPI1012638B8 (pt) métodos e intermediários para preparar agentes farmacêuticos
EA201300250A1 (ru) Оксадиазольные ингибиторы продуцирования лейкотриена
ATE517869T1 (de) Herstellung substituierter morphinan-6-one und salzen und zwischenprodukten davon
MY160392A (en) Triptolide prodrugs
CL2007003158A1 (es) Procedimiento de preparacion de compuestos derivados de quinazolina o sus sales farmaceuticamente aceptables; compuestos intermediarios; procedimiento de preparacion.
DK2190426T3 (da) Griseofulvin-analoger til behandling af cancer ved hæmning af centrosomal clusterdannelse
EA200702464A1 (ru) Способы получения фенольных 4-бифенилилазетидин-2-онов
ECSP10010498A (es) Procesos para la preparación de derivados de heteroarilo benzofusionados
ECSP088383A (es) Tetrahidroquinolinas, su síntesis e intermediarios campo de la invención
UA114611C2 (uk) Пестицидні композиції і способи, що їх стосуються
EA200900090A1 (ru) Бензиламины, способ их получения и их применение в качестве противовоспалительных средств
ECSP088151A (es) Diazepinoquinolinas, sintesis de las mismas, e intermediarios para obtenerlas
ECSP088360A (es) Métodos para preparar derivados de ácido glutámico
EA201001566A1 (ru) Новый класс спиропиперидинов для лечения нейродегенеративных заболеваний
ECSP088251A (es) Diazepinoquinolinas, sintesis de las mismas, e intermediarios para obtenerlas
ATE465152T1 (de) Verfahren zum herstellen von alkylaniliden aus halogenbenzolderivaten
BRPI0914400A2 (pt) "processo para a síntese de um composto"
BR112012009611A2 (pt) ''processo para a preparação de um composto de fómula (i)''
WO2008008327A3 (en) Xinafoate salt of a substituted 5-oxazol-2-yl-quinoline compound
BRPI0816830A2 (pt) Processo para a preparação de derivados de 2,2-diflúor-etilamina por hidrogenação de amida
CR9208A (es) Procesos para la preparacion de alcoholes de aminoetoxibencilo