ECSP099444A - Compuestos y métodos para modulación de cinasas, e indicaciones para ello - Google Patents
Compuestos y métodos para modulación de cinasas, e indicaciones para elloInfo
- Publication number
- ECSP099444A ECSP099444A EC2009009444A ECSP099444A ECSP099444A EC SP099444 A ECSP099444 A EC SP099444A EC 2009009444 A EC2009009444 A EC 2009009444A EC SP099444 A ECSP099444 A EC SP099444A EC SP099444 A ECSP099444 A EC SP099444A
- Authority
- EC
- Ecuador
- Prior art keywords
- compounds
- methods
- kinases
- indications
- modulation
- Prior art date
Links
- 102000001253 Protein Kinase Human genes 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 108060006633 protein kinase Proteins 0.000 title abstract 3
- 230000001594 aberrant effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Rheumatology (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
Abstract
Se describen compuestos activos sobre proteína cinasas, así como métodos para usar tales compuestos para tratar enfermedades y padecimientos asociados con actividad aberrante de proteína cinasas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87695306P | 2006-12-21 | 2006-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP099444A true ECSP099444A (es) | 2009-07-31 |
Family
ID=39281754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2009009444A ECSP099444A (es) | 2006-12-21 | 2009-06-18 | Compuestos y métodos para modulación de cinasas, e indicaciones para ello |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US7863289B2 (es) |
| EP (1) | EP2097414A1 (es) |
| JP (1) | JP2010514687A (es) |
| KR (1) | KR20090095654A (es) |
| CN (1) | CN101668757A (es) |
| AR (1) | AR064476A1 (es) |
| AU (1) | AU2007336906A1 (es) |
| BR (1) | BRPI0722088A2 (es) |
| CA (1) | CA2673000A1 (es) |
| CL (1) | CL2007003797A1 (es) |
| CO (1) | CO6190519A2 (es) |
| CR (1) | CR10860A (es) |
| EC (1) | ECSP099444A (es) |
| HN (1) | HN2009001202A (es) |
| MA (1) | MA31153B1 (es) |
| MX (1) | MX2009006162A (es) |
| MY (1) | MY148468A (es) |
| NO (1) | NO20092251L (es) |
| PE (2) | PE20081581A1 (es) |
| RU (1) | RU2009122436A (es) |
| TW (1) | TW200845975A (es) |
| UA (1) | UA98629C2 (es) |
| UY (1) | UY30816A1 (es) |
| WO (2) | WO2008079903A1 (es) |
Families Citing this family (179)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090118139A1 (en) * | 2000-11-07 | 2009-05-07 | Caliper Life Sciences, Inc. | Microfluidic method and system for enzyme inhibition activity screening |
| CN1925855B (zh) | 2003-12-19 | 2010-06-16 | 普莱希科公司 | 开发Ret调节剂的化合物和方法 |
| US7498342B2 (en) * | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
| MX2007014377A (es) * | 2005-05-17 | 2008-02-06 | Plexxikon Inc | Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina. |
| PL2395004T3 (pl) * | 2005-06-22 | 2016-08-31 | Plexxikon Inc | Pochodne pirolo[2,3-b]pirydyny jako inhibitory kinazy białkowej |
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| PE20081581A1 (es) | 2006-12-21 | 2008-11-12 | Plexxikon Inc | COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA |
| WO2008079909A1 (en) * | 2006-12-21 | 2008-07-03 | Plexxikon, Inc. | Pyrrolo [2,3-b] pyridines as kinase modulators |
| US7872018B2 (en) | 2006-12-21 | 2011-01-18 | Plexxikon, Inc. | Compounds and methods for kinase modulation, and indications therefor |
| MX2010000617A (es) | 2007-07-17 | 2010-05-17 | Plexxikon Inc | Compuestos y metodos para modulacion de cinasa, e indicaciones de estos. |
| EP2265270A1 (en) * | 2008-02-04 | 2010-12-29 | OSI Pharmaceuticals, Inc. | 2-aminopyridine kinase inhibitors |
| AR070317A1 (es) * | 2008-02-06 | 2010-03-31 | Osi Pharm Inc | Furo (3,2-c) piridina y tieno (3,2-c) piridinas |
| MX2010008198A (es) * | 2008-02-25 | 2010-08-23 | Hoffmann La Roche | Inhibidores de cinasa de pirrolopirazina. |
| CA2713718A1 (en) | 2008-02-25 | 2009-09-03 | F. Hoffmann-La Roche Ag | Pyrrolopyrazine kinase inhibitors |
| ATE517107T1 (de) | 2008-02-25 | 2011-08-15 | Hoffmann La Roche | Pyrrolopyrazinkinaseinhibitoren |
| CN101952295B (zh) | 2008-02-25 | 2013-11-20 | 霍夫曼-拉罗奇有限公司 | 吡咯并吡嗪激酶抑制剂 |
| PT2250172E (pt) | 2008-02-25 | 2011-11-30 | Hoffmann La Roche | Inibidores de pirrolpirazina-cinase |
| CL2009000448A1 (es) | 2008-02-29 | 2009-11-27 | Genentech Inc | Compuestos derivados de 3-sulfonilamino-n-(1h-pirazolo-[3,4-b]piridin-5il)benzamida; procesos de preparacion; compuestos intermediarios; composicion farmaceutica; y uso para el tratamiento del cancer, tal como sarcoma, carcinoma, adenoma, entre otros. |
| JP2011513329A (ja) * | 2008-02-29 | 2011-04-28 | アレイ バイオファーマ、インコーポレイテッド | RAF阻害化合物として使用されるイミダゾ[4,5−b]ピリジン誘導体 |
| MX2010009410A (es) * | 2008-02-29 | 2010-11-30 | Array Biopharma Inc | Compuestos del inhibidor de raf y métodos de uso de los mismos. |
| US20110003859A1 (en) * | 2008-02-29 | 2011-01-06 | Array Biopharma Inc. | N- (6-aminopyridin-3-yl) -3- (sulfonamido) benzamide derivatives as b-raf inhibitors for the treatment of cancer |
| US8158636B2 (en) | 2008-05-19 | 2012-04-17 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| US20110274661A1 (en) * | 2008-08-11 | 2011-11-10 | The University Of Chicago | Attentuated Herpesvirus Encoding a Mek Pathway Polypeptide |
| DK2350075T3 (da) | 2008-09-22 | 2014-05-26 | Array Biopharma Inc | Substituerede imidazo[1,2b]pyridazinforbindelser som trk-kinase-inhibitorer |
| MX2011004953A (es) | 2008-11-10 | 2011-12-14 | Vertex Pharma | Compuestos utiles como inhibidores de cinasa atr. |
| EP2356116A1 (en) * | 2008-11-20 | 2011-08-17 | OSI Pharmaceuticals, Inc. | Substituted pyrroloý2,3-b¨-pyridines and-pyrazines |
| ES2921576T3 (es) | 2008-12-19 | 2022-08-29 | Vertex Pharma | Compuestos útiles como inhibidores de la quinasa ATR |
| TW201036972A (en) * | 2009-03-11 | 2010-10-16 | Plexxikon Inc | Compounds and uses thereof |
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| US20080167338A1 (en) | 2008-07-10 |
| PE20081581A1 (es) | 2008-11-12 |
| JP2010514687A (ja) | 2010-05-06 |
| NO20092251L (no) | 2009-07-15 |
| MX2009006162A (es) | 2009-06-19 |
| AR064476A1 (es) | 2009-04-01 |
| KR20090095654A (ko) | 2009-09-09 |
| UA98629C2 (ru) | 2012-06-11 |
| BRPI0722088A2 (pt) | 2016-03-22 |
| MA31153B1 (fr) | 2010-02-01 |
| PE20121126A1 (es) | 2012-08-24 |
| TW200845975A (en) | 2008-12-01 |
| US20110092538A1 (en) | 2011-04-21 |
| HN2009001202A (es) | 2012-06-04 |
| CN101668757A (zh) | 2010-03-10 |
| CL2007003797A1 (es) | 2008-07-18 |
| CO6190519A2 (es) | 2010-08-19 |
| CR10860A (es) | 2009-06-30 |
| RU2009122436A (ru) | 2011-01-27 |
| EP2097414A1 (en) | 2009-09-09 |
| WO2008079903A1 (en) | 2008-07-03 |
| MY148468A (en) | 2013-04-30 |
| UY30816A1 (es) | 2008-07-31 |
| WO2008079906A1 (en) | 2008-07-03 |
| AU2007336906A1 (en) | 2008-07-03 |
| CA2673000A1 (en) | 2008-07-03 |
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