ECSP10010664A - Derivados de urea heterocíclicos para el tratamiento de infecciones bacterianas - Google Patents

Derivados de urea heterocíclicos para el tratamiento de infecciones bacterianas

Info

Publication number
ECSP10010664A
ECSP10010664A EC2010010664A ECSP10010664A ECSP10010664A EC SP10010664 A ECSP10010664 A EC SP10010664A EC 2010010664 A EC2010010664 A EC 2010010664A EC SP10010664 A ECSP10010664 A EC SP10010664A EC SP10010664 A ECSP10010664 A EC SP10010664A
Authority
EC
Ecuador
Prior art keywords
treatment
bacterial infections
urea derivatives
heterocyclic urea
heterocyclic
Prior art date
Application number
EC2010010664A
Other languages
English (en)
Inventor
Pamela Hill
Brian Sherer
John Irvin Manchester
Allison Laura Choy
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40823415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP10010664(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP10010664A publication Critical patent/ECSP10010664A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Se describen compuestos de fórmula (I) y sus sales farmacéuticamente aceptables. También se describen procedimientos para su preparación, composiciones farmacéuticas que los contienen, su uso como medicamentos y su uso en el tratamiento de infecciones bacterianas
EC2010010664A 2008-06-04 2010-12-07 Derivados de urea heterocíclicos para el tratamiento de infecciones bacterianas ECSP10010664A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5873608P 2008-06-04 2008-06-04

Publications (1)

Publication Number Publication Date
ECSP10010664A true ECSP10010664A (es) 2011-01-31

Family

ID=40823415

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010010664A ECSP10010664A (es) 2008-06-04 2010-12-07 Derivados de urea heterocíclicos para el tratamiento de infecciones bacterianas

Country Status (23)

Country Link
US (1) US8283361B2 (es)
EP (1) EP2300463A1 (es)
JP (1) JP2011522026A (es)
KR (1) KR20110014710A (es)
CN (1) CN102105469A (es)
AR (1) AR072045A1 (es)
AU (1) AU2009254930A1 (es)
BR (1) BRPI0915471A2 (es)
CA (1) CA2725568A1 (es)
CL (1) CL2009001349A1 (es)
CO (1) CO6382176A2 (es)
CR (1) CR11825A (es)
DO (1) DOP2010000373A (es)
EA (1) EA201001858A1 (es)
EC (1) ECSP10010664A (es)
IL (1) IL209503A0 (es)
MX (1) MX2010013310A (es)
PE (1) PE20100155A1 (es)
SV (1) SV2010003752A (es)
TW (1) TW201000475A (es)
UY (1) UY31864A (es)
WO (1) WO2009147433A1 (es)
ZA (1) ZA201008610B (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100130737A1 (en) * 2005-02-18 2010-05-27 Takeda Pharmaceutical Company Limited Regulating Agent of GPR34 Receptor Function
TW201102065A (en) * 2009-05-29 2011-01-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
WO2010142978A1 (en) * 2009-06-08 2010-12-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
KR20130012072A (ko) 2010-03-31 2013-01-31 액테리온 파마슈티칼 리미티드 항박테리아성 이소퀴놀린-３-일우레아 유도체
AR088729A1 (es) 2011-03-29 2014-07-02 Actelion Pharmaceuticals Ltd Derivados de 3-ureidoisoquinolin-8-ilo y una composicion farmaceutica
CN105067814A (zh) * 2015-07-24 2015-11-18 中国科学院成都生物研究所 解旋酶水解atp活性测定方法
WO2018048882A1 (en) 2016-09-06 2018-03-15 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
WO2018074880A2 (ko) * 2016-10-20 2018-04-26 한국화학연구원 퀴놀린 4-온 유도체 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 폐렴의 예방 또는 치료용 약학적 조성물
CN110446699A (zh) 2017-03-24 2019-11-12 大正制药株式会社 2（1h）-喹啉酮衍生物
CN111808089B (zh) * 2019-04-10 2023-04-11 四川大学华西医院 一种治疗糖尿病的药物依格列净或其衍生物的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993000342A1 (en) 1991-06-21 1993-01-07 Boehringer Mannheim Italia S.P.A. 2-amino-4-aryl-thiazoles with antiasthmatic and anti-inflammatory activities on the respiratory tract
BR0116216A (pt) 2000-12-15 2004-08-17 Vertex Pharma Inibidores de girase e seus usos
AR042956A1 (es) 2003-01-31 2005-07-13 Vertex Pharma Inhibidores de girasa y usos de los mismos
EP1861393A2 (en) * 2005-03-04 2007-12-05 AstraZeneca AB Pyrrole derivatives as dna gyrase and topoisomerase inhibitors
US8022816B2 (en) 2005-03-21 2011-09-20 Vela Systems, Inc. System and method for field management using radio frequency tags
US7569907B2 (en) 2005-03-28 2009-08-04 Cooper Technologies Company Hybrid chip fuse assembly having wire leads and fabrication method therefor
WO2006109259A1 (en) 2005-04-13 2006-10-19 Koninklijke Philips Electronics N.V. Encoding with watermarking prior to phase modulation
EP1991545A2 (en) * 2005-12-23 2008-11-19 AstraZeneca AB Antibacterial pyrrolopyridines, pyrrolopyrimidines, and pyrroloazepines
DE102006012337B3 (de) 2006-03-17 2007-11-29 Amphenol-Tuchel Electronics Gmbh Elektrischer Steckverbinder
ES2363178T3 (es) * 2006-12-04 2011-07-26 Astrazeneca Ab Compuestos de urea policíclicos antibacterianos.
CN201038186Y (zh) 2007-03-08 2008-03-19 鹤山丽得电子实业有限公司 一种大功率led
TW200940537A (en) * 2008-02-26 2009-10-01 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
WO2009110688A2 (ko) 2008-03-06 2009-09-11 Jang Gum Sik 태양광 발전 장치
WO2010142978A1 (en) * 2009-06-08 2010-12-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof

Also Published As

Publication number Publication date
PE20100155A1 (es) 2010-03-25
TW201000475A (en) 2010-01-01
EP2300463A1 (en) 2011-03-30
US20100190745A1 (en) 2010-07-29
CN102105469A (zh) 2011-06-22
BRPI0915471A2 (pt) 2017-06-27
CO6382176A2 (es) 2012-02-15
UY31864A (es) 2010-01-29
EA201001858A1 (ru) 2011-08-30
ZA201008610B (en) 2012-08-29
DOP2010000373A (es) 2011-01-15
CL2009001349A1 (es) 2010-12-31
SV2010003752A (es) 2011-04-14
AU2009254930A1 (en) 2009-12-10
AR072045A1 (es) 2010-08-04
JP2011522026A (ja) 2011-07-28
KR20110014710A (ko) 2011-02-11
CA2725568A1 (en) 2009-12-10
MX2010013310A (es) 2011-03-01
IL209503A0 (en) 2011-01-31
CR11825A (es) 2011-02-04
US8283361B2 (en) 2012-10-09
WO2009147433A1 (en) 2009-12-10

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