ECSP109969A - Terapia especifica y medicamento que usan ligando de integrina para tratar cancer - Google Patents
Terapia especifica y medicamento que usan ligando de integrina para tratar cancerInfo
- Publication number
- ECSP109969A ECSP109969A EC2010009969A ECSP109969A ECSP109969A EC SP109969 A ECSP109969 A EC SP109969A EC 2010009969 A EC2010009969 A EC 2010009969A EC SP109969 A ECSP109969 A EC SP109969A EC SP109969 A ECSP109969 A EC SP109969A
- Authority
- EC
- Ecuador
- Prior art keywords
- therapy
- integrine
- treat cancer
- product used
- medicinal product
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La invención se refiere a una terapia de combinación para tratamiento de tumores y metástasis tumoral, que comprende la administración de ligandos de integrina, preferentemente antagonistas de integrina, conjuntamente con agentes co-terapéuticos o formas de terapia que tienen eficiencia sinérgica cuando se administran consecutivamente con los ligandos, tal como agentes quimioterapéuticos y/o terapia de radiación. La terapia da por resultado un incremento potencial sinérgico del efecto de inhibición de cada producto terapéutico individual en la proliferación de células tumorales, produciendo un tratamiento más efectivo que lo encontrado al administrar un componente individual solo, concurrentemente o no en el régimen de dosis de la presente invención.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07014070 | 2007-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP109969A true ECSP109969A (es) | 2010-03-31 |
Family
ID=39402737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2010009969A ECSP109969A (es) | 2007-07-18 | 2010-02-17 | Terapia especifica y medicamento que usan ligando de integrina para tratar cancer |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20100069302A1 (es) |
| EP (4) | EP2441464B1 (es) |
| JP (3) | JP2010516645A (es) |
| KR (2) | KR20090108713A (es) |
| CN (2) | CN101588812A (es) |
| AU (2) | AU2008207095B2 (es) |
| BR (2) | BRPI0806596A2 (es) |
| CA (2) | CA2675813A1 (es) |
| CO (1) | CO6382135A2 (es) |
| DK (1) | DK2101805T3 (es) |
| EA (2) | EA017864B1 (es) |
| EC (1) | ECSP109969A (es) |
| ES (2) | ES2472450T3 (es) |
| IL (1) | IL199696A0 (es) |
| MX (1) | MX2009007597A (es) |
| PL (1) | PL2101805T3 (es) |
| PT (1) | PT2101805E (es) |
| WO (2) | WO2008087025A2 (es) |
| ZA (1) | ZA200905703B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010516645A (ja) * | 2007-01-18 | 2010-05-20 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌を治療するためのインテグリンリガンドを用いる特異的療法および薬剤 |
| US20110230423A1 (en) * | 2008-11-20 | 2011-09-22 | Martin Andreas Picard | Therapy and medicament using integrin ligands for treating cancer |
| US20120130146A1 (en) * | 2009-05-25 | 2012-05-24 | Merck Patent Gmbh | Continuous administration of cilengitide in cancer treatments |
| US8916574B2 (en) | 2009-09-28 | 2014-12-23 | Qilu Pharmaceutical Co., Ltd. | 4-(substituted anilino)-quinazoline derivatives useful as tyrosine kinase inhibitors |
| WO2011146819A2 (en) * | 2010-05-20 | 2011-11-24 | Dmd Therapies, Llc | METHODS AND COMPOSITIONS FOR TREATMENT NF-κB-MEDIATED AND α7 INTEGRIN-SUPPRESSED DISEASES |
| KR20150091504A (ko) * | 2012-12-07 | 2015-08-11 | 백스터 인터내셔널 인코포레이티드 | 항―mif 항체 세포 이동 검정법 |
| US20160317531A1 (en) * | 2013-06-21 | 2016-11-03 | The General Hospital Corporation | Ribonucleotide reductase inhibitors sensitize tumor cells to dna damaging agents |
| KR101579054B1 (ko) * | 2014-03-26 | 2015-12-21 | 한국원자력의학원 | 포도필로톡신 아세테이트를 유효 성분으로 포함하는 방사선치료 증진제 |
| CN106714835A (zh) * | 2014-09-17 | 2017-05-24 | 默克专利股份公司 | 治疗骨转移疾病的方法、其药物以及预测治疗骨转移疾病的临床结果的方法 |
| CN106999540B (zh) * | 2014-10-30 | 2020-10-27 | 比格基因有限公司 | 组合疗法 |
| EP3207937A1 (en) | 2016-02-17 | 2017-08-23 | Royal College of Surgeons in Ireland | A method of treating or preventing sepsis |
| CN105906692A (zh) * | 2016-03-11 | 2016-08-31 | 李书鹏 | cRGD-厄洛替尼缀合物及其制备方法 |
| GB2554333A (en) * | 2016-04-26 | 2018-04-04 | Big Dna Ltd | Combination therapy |
| WO2018145076A1 (en) * | 2017-02-06 | 2018-08-09 | Expression Pathology, Inc. | Quantifying mgmt protein for optimal cancer therapy |
| WO2022157336A1 (en) | 2021-01-22 | 2022-07-28 | Royal College Of Surgeons In Ireland | Treatment of coronavirus |
| KR102763598B1 (ko) * | 2022-05-18 | 2025-02-07 | 한국원자력의학원 | 포도필로톡신 유도체를 유효성분으로 포함하는 방사선 치료 증진제 |
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| US4792525A (en) | 1982-08-04 | 1988-12-20 | La Jolla Cancer Research Foundation | Tetrapeptide |
| US4578079A (en) | 1982-08-04 | 1986-03-25 | La Jolla Cancer Research Foundation | Tetrapeptide |
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| FR2768734B1 (fr) | 1997-09-24 | 2000-01-28 | Roussel Uclaf | Nouveaux composes tricycliques, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
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| FR2768736B1 (fr) | 1997-09-24 | 2000-05-26 | Roussel Uclaf | Nouveaux composes tricycliques, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
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| WO1999030713A1 (en) | 1997-12-17 | 1999-06-24 | Merck & Co., Inc. | Integrin receptor antagonists |
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| WO2000006169A1 (en) | 1998-07-29 | 2000-02-10 | Merck & Co., Inc. | Integrin receptor antagonists |
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| JP2010516645A (ja) * | 2007-01-18 | 2010-05-20 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌を治療するためのインテグリンリガンドを用いる特異的療法および薬剤 |
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2008
- 2008-01-17 JP JP2009545872A patent/JP2010516645A/ja active Pending
- 2008-01-17 ES ES11009510.6T patent/ES2472450T3/es active Active
- 2008-01-17 PT PT87070934T patent/PT2101805E/pt unknown
- 2008-01-17 BR BRPI0806596-9A patent/BRPI0806596A2/pt not_active IP Right Cessation
- 2008-01-17 KR KR1020097017119A patent/KR20090108713A/ko not_active Ceased
- 2008-01-17 WO PCT/EP2008/000328 patent/WO2008087025A2/en not_active Ceased
- 2008-01-17 CA CA002675813A patent/CA2675813A1/en not_active Abandoned
- 2008-01-17 EA EA200900912A patent/EA017864B1/ru not_active IP Right Cessation
- 2008-01-17 US US12/523,491 patent/US20100069302A1/en not_active Abandoned
- 2008-01-17 AU AU2008207095A patent/AU2008207095B2/en not_active Ceased
- 2008-01-17 EP EP11009510.6A patent/EP2441464B1/en not_active Not-in-force
- 2008-01-17 MX MX2009007597A patent/MX2009007597A/es active IP Right Grant
- 2008-01-17 EP EP08707093A patent/EP2101805B1/en not_active Not-in-force
- 2008-01-17 PL PL08707093T patent/PL2101805T3/pl unknown
- 2008-01-17 ES ES08707093T patent/ES2399159T3/es active Active
- 2008-01-17 CN CNA2008800024456A patent/CN101588812A/zh active Pending
- 2008-01-17 DK DK08707093.4T patent/DK2101805T3/da active
- 2008-07-17 KR KR1020107003515A patent/KR20100043242A/ko not_active Withdrawn
- 2008-07-17 CN CN200880024802A patent/CN101743013A/zh active Pending
- 2008-07-17 CA CA2693862A patent/CA2693862A1/en not_active Abandoned
- 2008-07-17 AU AU2008277904A patent/AU2008277904A1/en not_active Abandoned
- 2008-07-17 EP EP08774010A patent/EP2164506A2/en not_active Ceased
- 2008-07-17 JP JP2010516420A patent/JP2010533665A/ja active Pending
- 2008-07-17 US US12/668,823 patent/US20100190957A1/en not_active Abandoned
- 2008-07-17 BR BRPI0813513-4A2A patent/BRPI0813513A2/pt not_active IP Right Cessation
- 2008-07-17 EP EP12007334.1A patent/EP2578225A1/en not_active Withdrawn
- 2008-07-17 WO PCT/EP2008/005831 patent/WO2009010287A2/en not_active Ceased
- 2008-07-17 EA EA201000127A patent/EA201000127A1/ru unknown
-
2009
- 2009-07-05 IL IL199696A patent/IL199696A0/en unknown
- 2009-08-17 ZA ZA200905703A patent/ZA200905703B/xx unknown
-
2010
- 2010-01-15 CO CO10003771A patent/CO6382135A2/es not_active Application Discontinuation
- 2010-02-17 EC EC2010009969A patent/ECSP109969A/es unknown
-
2013
- 2013-10-18 JP JP2013217677A patent/JP2014015482A/ja active Pending
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