ECSP11010840A - Anticuerpos anti-il-13 modificados, composiciones, métodos y usos - Google Patents

Anticuerpos anti-il-13 modificados, composiciones, métodos y usos

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Publication number
ECSP11010840A
ECSP11010840A EC2011010840A ECSP11010840A ECSP11010840A EC SP11010840 A ECSP11010840 A EC SP11010840A EC 2011010840 A EC2011010840 A EC 2011010840A EC SP11010840 A ECSP11010840 A EC SP11010840A EC SP11010840 A ECSP11010840 A EC SP11010840A
Authority
EC
Ecuador
Prior art keywords
methods
modified antibodies
compositions
immunospecific
fragment
Prior art date
Application number
EC2011010840A
Other languages
English (en)
Inventor
Jill Giles-Komar
Shu-Hai Zhao
Jill Carton
Gopalan Raghunathan
Ronald V Swanson
Ellen Chi
Johan Fransson
Wendy Cordier
Juan C Almagro
Linus Hyun
Neil Karyn T O
Hong Mimi Zhou
Alexey V Teplyakov
Yiging Feng
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of ECSP11010840A publication Critical patent/ECSP11010840A/es

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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/565—Complementarity determining region [CDR]
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Abstract

La presente invención se relaciona con anticuerpos modificados inmunoespecíficos para la proteína interleucina-13 humana (IL-13) o fragmento de esta, así como con los métodos de preparar y usarla, incluso las indicaciones terapéuticas.
EC2011010840A 2008-08-20 2011-02-18 Anticuerpos anti-il-13 modificados, composiciones, métodos y usos ECSP11010840A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9047208P 2008-08-20 2008-08-20
US9723208P 2008-09-16 2008-09-16

Publications (1)

Publication Number Publication Date
ECSP11010840A true ECSP11010840A (es) 2011-03-31

Family

ID=41707613

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2011010840A ECSP11010840A (es) 2008-08-20 2011-02-18 Anticuerpos anti-il-13 modificados, composiciones, métodos y usos

Country Status (20)

Country Link
US (2) US8399630B2 (es)
EP (1) EP2328615A2 (es)
JP (2) JP2012506695A (es)
KR (1) KR20110043786A (es)
CN (1) CN102264391A (es)
AR (1) AR073088A1 (es)
AU (1) AU2009283008A1 (es)
BR (1) BRPI0917370A2 (es)
CA (1) CA2734645A1 (es)
CO (1) CO6341573A2 (es)
CR (1) CR20110152A (es)
EA (1) EA201170357A1 (es)
EC (1) ECSP11010840A (es)
IL (1) IL211087A0 (es)
MX (1) MX2011001909A (es)
NI (1) NI201100040A (es)
NZ (1) NZ591098A (es)
UY (1) UY32060A (es)
WO (1) WO2010021874A2 (es)
ZA (1) ZA201102081B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7306925B2 (en) 2001-11-09 2007-12-11 Vanderbilt University Phage antibodies to radiation-inducible neoantigens
US7906102B2 (en) 2001-10-03 2011-03-15 Vanderbilt University Ligands to radiation-induced molecules
EP2328615A2 (en) * 2008-08-20 2011-06-08 Centocor Ortho Biotech Inc. Engineered anti-il-13 antibodies, compositions, methods and uses
GB0904214D0 (en) 2009-03-11 2009-04-22 Ucb Pharma Sa Biological products
US8580714B2 (en) * 2009-10-14 2013-11-12 Janssen Biotech, Inc. Methods of affinity maturing antibodies
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