ECSP11010840A - Anticuerpos anti-il-13 modificados, composiciones, métodos y usos - Google Patents

Anticuerpos anti-il-13 modificados, composiciones, métodos y usos

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Publication number
ECSP11010840A
ECSP11010840A EC2011010840A ECSP11010840A ECSP11010840A EC SP11010840 A ECSP11010840 A EC SP11010840A EC 2011010840 A EC2011010840 A EC 2011010840A EC SP11010840 A ECSP11010840 A EC SP11010840A EC SP11010840 A ECSP11010840 A EC SP11010840A
Authority
EC
Ecuador
Prior art keywords
methods
modified antibodies
compositions
immunospecific
fragment
Prior art date
Application number
EC2011010840A
Other languages
English (en)
Inventor
Jill Giles-Komar
Shu-Hai Zhao
Jill Carton
Gopalan Raghunathan
Ronald V Swanson
Ellen Chi
Johan Fransson
Wendy Cordier
Juan C Almagro
Linus Hyun
Neil Karyn T O
Hong Mimi Zhou
Alexey V Teplyakov
Yiging Feng
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of ECSP11010840A publication Critical patent/ECSP11010840A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
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    • GPHYSICS
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    • G01N2333/52Assays involving cytokines
    • G01N2333/54Interleukins [IL]
    • G01N2333/5437IL-13

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Abstract

La presente invención se relaciona con anticuerpos modificados inmunoespecíficos para la proteína interleucina-13 humana (IL-13) o fragmento de esta, así como con los métodos de preparar y usarla, incluso las indicaciones terapéuticas.
EC2011010840A 2008-08-20 2011-02-18 Anticuerpos anti-il-13 modificados, composiciones, métodos y usos ECSP11010840A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9047208P 2008-08-20 2008-08-20
US9723208P 2008-09-16 2008-09-16

Publications (1)

Publication Number Publication Date
ECSP11010840A true ECSP11010840A (es) 2011-03-31

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ID=41707613

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2011010840A ECSP11010840A (es) 2008-08-20 2011-02-18 Anticuerpos anti-il-13 modificados, composiciones, métodos y usos

Country Status (20)

Country Link
US (2) US8399630B2 (es)
EP (1) EP2328615A2 (es)
JP (2) JP2012506695A (es)
KR (1) KR20110043786A (es)
CN (1) CN102264391A (es)
AR (1) AR073088A1 (es)
AU (1) AU2009283008A1 (es)
BR (1) BRPI0917370A2 (es)
CA (1) CA2734645A1 (es)
CO (1) CO6341573A2 (es)
CR (1) CR20110152A (es)
EA (1) EA201170357A1 (es)
EC (1) ECSP11010840A (es)
IL (1) IL211087A0 (es)
MX (1) MX2011001909A (es)
NI (1) NI201100040A (es)
NZ (1) NZ591098A (es)
UY (1) UY32060A (es)
WO (1) WO2010021874A2 (es)
ZA (1) ZA201102081B (es)

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AU2009283008A1 (en) * 2008-08-20 2010-02-25 Centocor Ortho Biotech Inc. Engineered anti-IL-13 antibodies, compositions, methods and uses
GB0904214D0 (en) 2009-03-11 2009-04-22 Ucb Pharma Sa Biological products
US8580714B2 (en) * 2009-10-14 2013-11-12 Janssen Biotech, Inc. Methods of affinity maturing antibodies
JOP20210044A1 (ar) * 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
WO2013019730A1 (en) * 2011-07-29 2013-02-07 The Washington University Antibodies to tip-1 and grp78
US9758591B2 (en) 2012-08-24 2017-09-12 The Regents Of The University Of California Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis
AU2014249243C1 (en) * 2013-03-13 2019-08-08 Imaginab, Inc. Antigen binding constructs to CD8
WO2016014939A1 (en) 2014-07-24 2016-01-28 Washington University Compositions targeting radiation-induced molecules and methods of use thereof
WO2017027325A1 (en) 2015-08-07 2017-02-16 Imaginab, Inc. Antigen binding constructs to target molecules
EA037960B1 (ru) 2016-04-27 2021-06-15 Эббви Инк. Способ лечения эозинофильного эзофагита с применением антитела против il-13
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