ECSP17068922A - Métodos de reparación y regeneración tisular - Google Patents

Métodos de reparación y regeneración tisular

Info

Publication number
ECSP17068922A
ECSP17068922A ECIEPI201768922A ECPI201768922A ECSP17068922A EC SP17068922 A ECSP17068922 A EC SP17068922A EC IEPI201768922 A ECIEPI201768922 A EC IEPI201768922A EC PI201768922 A ECPI201768922 A EC PI201768922A EC SP17068922 A ECSP17068922 A EC SP17068922A
Authority
EC
Ecuador
Prior art keywords
site
injury site
injury
induces
tissue
Prior art date
Application number
ECIEPI201768922A
Other languages
English (en)
Inventor
Yujian James Kang
Original Assignee
Innolife Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innolife Co Ltd filed Critical Innolife Co Ltd
Publication of ECSP17068922A publication Critical patent/ECSP17068922A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Prostheses (AREA)

Abstract

La divulgación proporciona el suministro local de un elemento traza en un sitio de daño tisular, que desencadena el mecanismo de reparación tisular inherente del cuerpo. El suministro local de cobre en el sitio de la lesión induce la migración (es decir, la migración dirigida) de células madre hacia el sitio de la lesión, desencadena la diferenciación de células madre en el sitio de la lesión, induce la regeneración tisular en el sitio de la lesión, induce moléculas de señalización que desencadenan la regeneración tisular, revierte el daño en el sitio de la lesión y/o reconstruye el microambiente de células neurofibrilares y células neurosecretoras en el sitio de la lesión. En otro aspecto, se desvela el suministro de un elemento traza (por ejemplo, cobre) directamente en el sitio de la lesión y los métodos asociados.
ECIEPI201768922A 2015-04-22 2017-10-17 Métodos de reparación y regeneración tisular ECSP17068922A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2015/077136 WO2016168993A1 (en) 2015-04-22 2015-04-22 Methods of tissue repair and regeneration

Publications (1)

Publication Number Publication Date
ECSP17068922A true ECSP17068922A (es) 2018-02-28

Family

ID=57142823

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI201768922A ECSP17068922A (es) 2015-04-22 2017-10-17 Métodos de reparación y regeneración tisular

Country Status (25)

Country Link
US (1) US11077138B2 (es)
EP (1) EP3285782B1 (es)
JP (2) JP6895388B2 (es)
KR (2) KR20170137919A (es)
CN (1) CN107921062B (es)
AU (1) AU2016250971B2 (es)
BR (1) BR112017022355A2 (es)
CA (1) CA2982840C (es)
CL (1) CL2017002600A1 (es)
CO (1) CO2017010382A2 (es)
DK (1) DK3285782T3 (es)
EA (1) EA038598B1 (es)
EC (1) ECSP17068922A (es)
ES (1) ES2898655T3 (es)
HK (1) HK1251181A1 (es)
HU (1) HUE056650T2 (es)
IL (1) IL255116B (es)
MX (1) MX2017013122A (es)
MY (1) MY189322A (es)
NZ (1) NZ736516A (es)
PE (1) PE20180240A1 (es)
SG (1) SG11201708431QA (es)
TW (1) TWI702956B (es)
UA (1) UA124332C2 (es)
WO (2) WO2016168993A1 (es)

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TWI615127B (zh) * 2017-01-17 2018-02-21 正崴精密工業股份有限公司 計算血壓的方法及其裝置
WO2018217710A1 (en) * 2017-05-22 2018-11-29 The Regents Of The University Of California Micro/nanobubble solutions for tissue preservation and generation thereof
TWI635469B (zh) * 2017-08-29 2018-09-11 國立臺北商業大學 用於反應力訓練的電腦程式產品
TWI634528B (zh) * 2017-08-29 2018-09-01 國立臺北商業大學 用於評估認知能力的電腦程式產品
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CN114010163B (zh) * 2021-12-02 2023-12-19 中国中医科学院医学实验中心 基于光学成像的表皮细胞迁移定位系统及方法
CN114469897B (zh) * 2022-01-12 2023-02-28 上海市胸科医院 靶向治疗心肌梗死的锂皂石复合递送材料及其制备与应用
CN115177786A (zh) * 2022-07-14 2022-10-14 山东大学 一种原位负载蒙脱土/纳米羟基磷灰石的壳聚糖复合支架材料及其制备方法
WO2024237752A1 (ko) * 2023-05-12 2024-11-21 국립해양생물자원관 다중구리 산화효소 펩타이드 및 이로부터 유래된 펩타이드를 포함하는 상처 치유 또는 피부 재생용 조성물
CN117547554B (zh) * 2024-01-12 2024-05-14 山东康根源生物集团有限公司 一种间充质干细胞修复制剂及其制备方法
CN118879625A (zh) * 2024-07-24 2024-11-01 南方医科大学珠江医院 一种硫化铜工程化干细胞外泌体的制备方法及其应用
TWI924567B (zh) * 2025-07-31 2026-05-01 明志科技大學 結合α-酮戊二酸之聚離胺酸奈米羥基磷灰石及其用途

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WO2017049529A1 (en) 2015-09-24 2017-03-30 Innolife Co., Ltd. A pharmaceutical composition comprising a copper chelating tetramine and the use thereof

Also Published As

Publication number Publication date
DK3285782T3 (da) 2021-12-06
SG11201708431QA (en) 2017-11-29
MY189322A (en) 2022-02-04
CN107921062B (zh) 2021-03-02
MX2017013122A (es) 2018-06-18
HUE056650T2 (hu) 2022-02-28
IL255116A0 (en) 2017-12-31
BR112017022355A2 (pt) 2018-07-10
IL255116B (en) 2020-10-29
WO2016168993A1 (en) 2016-10-27
EP3285782A4 (en) 2018-12-12
CL2017002600A1 (es) 2018-03-23
JP2018520090A (ja) 2018-07-26
KR102347010B1 (ko) 2022-01-04
JP2020143158A (ja) 2020-09-10
US20180099008A1 (en) 2018-04-12
US11077138B2 (en) 2021-08-03
PE20180240A1 (es) 2018-01-31
CN107921062A (zh) 2018-04-17
JP6895388B2 (ja) 2021-06-30
HK1247825A1 (zh) 2018-10-05
AU2016250971A1 (en) 2017-11-02
EA201792307A1 (ru) 2018-06-29
CO2017010382A2 (es) 2018-01-05
AU2016250971B2 (en) 2021-04-29
EA038598B1 (ru) 2021-09-21
EP3285782B1 (en) 2021-09-08
ES2898655T3 (es) 2022-03-08
TWI702956B (zh) 2020-09-01
NZ736516A (en) 2019-04-26
EP3285782A1 (en) 2018-02-28
KR20200000458A (ko) 2020-01-02
WO2016169416A1 (en) 2016-10-27
HK1251181A1 (zh) 2019-01-25
CA2982840C (en) 2022-10-25
TW201642876A (zh) 2016-12-16
KR20170137919A (ko) 2017-12-13
CA2982840A1 (en) 2016-10-27
UA124332C2 (uk) 2021-09-01

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