ECSP22004680A - Anticuerpos anti-angpt2 - Google Patents
Anticuerpos anti-angpt2Info
- Publication number
- ECSP22004680A ECSP22004680A ECSENADI20224680A ECDI202204680A ECSP22004680A EC SP22004680 A ECSP22004680 A EC SP22004680A EC SENADI20224680 A ECSENADI20224680 A EC SENADI20224680A EC DI202204680 A ECDI202204680 A EC DI202204680A EC SP22004680 A ECSP22004680 A EC SP22004680A
- Authority
- EC
- Ecuador
- Prior art keywords
- angpt2
- angpt2 antibodies
- antibodies
- angiopoietin
- diagnosis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a anticuerpos neutralizantes anti-angiopoyetina 2 (ANGPT2) novedosos para métodos de tratamiento y diagnóstico y una composición en la que se usan.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962867253P | 2019-06-27 | 2019-06-27 | |
| US202063013022P | 2020-04-21 | 2020-04-21 | |
| PCT/US2020/039477 WO2020264065A1 (en) | 2019-06-27 | 2020-06-25 | Anti-angpt2 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP22004680A true ECSP22004680A (es) | 2022-02-25 |
Family
ID=71662321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSENADI20224680A ECSP22004680A (es) | 2019-06-27 | 2022-01-19 | Anticuerpos anti-angpt2 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US11396539B2 (es) |
| EP (1) | EP3990489A1 (es) |
| JP (1) | JP7649756B2 (es) |
| KR (1) | KR20220028032A (es) |
| CN (1) | CN114080396B (es) |
| AU (1) | AU2020308569A1 (es) |
| BR (1) | BR112021024176A2 (es) |
| CA (1) | CA3140071A1 (es) |
| CL (1) | CL2021003367A1 (es) |
| CO (1) | CO2021017414A2 (es) |
| CR (1) | CR20210683A (es) |
| EC (1) | ECSP22004680A (es) |
| IL (1) | IL289160A (es) |
| JO (1) | JOP20210339A1 (es) |
| MA (1) | MA56394A (es) |
| MX (1) | MX2021015743A (es) |
| PE (1) | PE20220809A1 (es) |
| PH (1) | PH12021553117A1 (es) |
| SA (1) | SA521431223B1 (es) |
| TW (1) | TWI877179B (es) |
| WO (1) | WO2020264065A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI877179B (zh) * | 2019-06-27 | 2025-03-21 | 德商百靈佳殷格翰國際股份有限公司 | 抗-angpt2抗體 |
Family Cites Families (49)
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| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4318980A (en) | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4419446A (en) | 1980-12-31 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA process utilizing a papilloma virus DNA as a vector |
| NZ201705A (en) | 1981-08-31 | 1986-03-14 | Genentech Inc | Recombinant dna method for production of hepatitis b surface antigen in yeast |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4434173A (en) | 1982-08-23 | 1984-02-28 | Pfizer Inc. | Bis-esters of 4,5-di(hydroxymethyl)-2-oxo-1,3-dioxole as antibacterial agents |
| US4601978A (en) | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US4965199A (en) | 1984-04-20 | 1990-10-23 | Genentech, Inc. | Preparation of functional human factor VIII in mammalian cells using methotrexate based selection |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| EP0206448B1 (en) | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| DK0752248T3 (da) | 1992-11-13 | 2000-11-13 | Idec Pharma Corp | Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| US6037454A (en) | 1996-11-27 | 2000-03-14 | Genentech, Inc. | Humanized anti-CD11a antibodies |
| US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
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| US20110227286A1 (en) * | 2010-03-18 | 2011-09-22 | Davies Janet L | Board Game and Method of Playing the Same |
| US9575073B2 (en) * | 2011-10-10 | 2017-02-21 | Rutgers, The State University Of New Jersey | Detection of high-risk intraductal papillary mucinous neoplasm and pancreatic adenocarcinoma |
| US20150044227A1 (en) * | 2012-03-08 | 2015-02-12 | Medimmune, Llc | Methods of treatment with angiopoietin-2 antibodies |
| US9828422B2 (en) * | 2013-07-29 | 2017-11-28 | Samsung Electronics Co., Ltd. | Anti-Ang2 antibody |
| CN105611944A (zh) | 2013-12-20 | 2016-05-25 | 豪夫迈·罗氏有限公司 | 抗ang2抗体和cd40激动剂的组合疗法 |
| AR100270A1 (es) * | 2014-05-19 | 2016-09-21 | Lilly Co Eli | Anticuerpos ang2 |
| CN107428820B (zh) * | 2014-11-19 | 2022-03-22 | 阿克松神经系统科学公司 | 在阿尔茨海默氏病中的人源化tau抗体 |
| CN109641051A (zh) | 2016-06-17 | 2019-04-16 | 美真达治疗公司 | 用于耗尽细胞的组合物和方法 |
| AU2017345786B2 (en) * | 2016-10-21 | 2024-08-01 | Adimab, Llc | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
| PE20210005A1 (es) * | 2017-09-29 | 2021-01-05 | Chugai Pharmaceutical Co Ltd | Molecula de union al antigeno multiespecifica que tiene actividad de sustitucion de la funcion de cofactor del factor viii de coagulacion de sangre (fviii) y formulacion farmaceutica que contiene tal molecula como ingrediente activo |
| TWI877179B (zh) * | 2019-06-27 | 2025-03-21 | 德商百靈佳殷格翰國際股份有限公司 | 抗-angpt2抗體 |
-
2020
- 2020-06-24 TW TW109121573A patent/TWI877179B/zh active
- 2020-06-25 KR KR1020227003085A patent/KR20220028032A/ko active Pending
- 2020-06-25 EP EP20742550.5A patent/EP3990489A1/en active Pending
- 2020-06-25 MX MX2021015743A patent/MX2021015743A/es unknown
- 2020-06-25 AU AU2020308569A patent/AU2020308569A1/en not_active Abandoned
- 2020-06-25 JP JP2021576151A patent/JP7649756B2/ja active Active
- 2020-06-25 BR BR112021024176A patent/BR112021024176A2/pt unknown
- 2020-06-25 CR CR20210683A patent/CR20210683A/es unknown
- 2020-06-25 CA CA3140071A patent/CA3140071A1/en active Pending
- 2020-06-25 WO PCT/US2020/039477 patent/WO2020264065A1/en not_active Ceased
- 2020-06-25 CN CN202080047312.1A patent/CN114080396B/zh active Active
- 2020-06-25 PE PE2021002220A patent/PE20220809A1/es unknown
- 2020-06-25 MA MA056394A patent/MA56394A/fr unknown
- 2020-06-25 US US16/911,419 patent/US11396539B2/en active Active
- 2020-06-25 PH PH1/2021/553117A patent/PH12021553117A1/en unknown
-
2021
- 2021-12-16 CL CL2021003367A patent/CL2021003367A1/es unknown
- 2021-12-17 CO CONC2021/0017414A patent/CO2021017414A2/es unknown
- 2021-12-20 IL IL289160A patent/IL289160A/en unknown
- 2021-12-27 JO JOP/2021/0339A patent/JOP20210339A1/ar unknown
- 2021-12-27 SA SA521431223A patent/SA521431223B1/ar unknown
-
2022
- 2022-01-19 EC ECSENADI20224680A patent/ECSP22004680A/es unknown
- 2022-06-17 US US17/842,904 patent/US20220363743A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW202115112A (zh) | 2021-04-16 |
| CA3140071A1 (en) | 2020-12-30 |
| TWI877179B (zh) | 2025-03-21 |
| MX2021015743A (es) | 2022-01-27 |
| WO2020264065A1 (en) | 2020-12-30 |
| CN114080396B (zh) | 2024-05-17 |
| CO2021017414A2 (es) | 2022-01-17 |
| SA521431223B1 (ar) | 2024-04-21 |
| CR20210683A (es) | 2022-02-23 |
| US20200407435A1 (en) | 2020-12-31 |
| EP3990489A1 (en) | 2022-05-04 |
| MA56394A (fr) | 2022-05-04 |
| KR20220028032A (ko) | 2022-03-08 |
| JP7649756B2 (ja) | 2025-03-21 |
| PE20220809A1 (es) | 2022-05-20 |
| US20220363743A1 (en) | 2022-11-17 |
| IL289160A (en) | 2022-02-01 |
| JP2022538062A (ja) | 2022-08-31 |
| AU2020308569A1 (en) | 2021-12-02 |
| BR112021024176A2 (pt) | 2022-03-22 |
| JOP20210339A1 (ar) | 2023-01-30 |
| CN114080396A (zh) | 2022-02-22 |
| CL2021003367A1 (es) | 2022-10-07 |
| PH12021553117A1 (en) | 2022-07-25 |
| US11396539B2 (en) | 2022-07-26 |
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