EE03087B1 - Adenosiini derivaadid, nende valmistamise meetodid ja neid sisaldavad ravimvormid - Google Patents

Adenosiini derivaadid, nende valmistamise meetodid ja neid sisaldavad ravimvormid

Info

Publication number: EE03087B1
Authority: EE; Estonia
Prior art keywords: preparation; methods; pct; formulations containing; adenosine derivatives
Prior art date: 1992-01-08

Application number

EE9400381A

Other languages

English (en)

Estonian (et)

Inventor

Bru-Magniez Nicole

G�ngor Timur

Teulon Jean-Marie

Original Assignee

Laboratoires Upsa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-08

Filing date

1994-11-22

Publication date

1998-04-15

1994-11-22 Application filed by Laboratoires Upsa filed Critical Laboratoires Upsa

1998-04-15 Publication of EE03087B1 publication Critical patent/EE03087B1/xx

Links

150000003835 adenosine derivatives Chemical class 0.000 title 1
238000009472 formulation Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
229940035676 analgesics Drugs 0.000 abstract 1
239000000730 antalgic agent Substances 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

EE9400381A 1992-01-08 1994-11-22 Adenosiini derivaadid, nende valmistamise meetodid ja neid sisaldavad ravimvormid EE03087B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9200138A FR2685918B1 (fr)	1992-01-08	1992-01-08	Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.
PCT/FR1992/001241 WO1993014102A1 (fr)	1992-01-08	1992-12-29	Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant

Publications (1)

Publication Number	Publication Date
EE03087B1 true EE03087B1 (et)	1998-04-15

Family

ID=9425478

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9400381A EE03087B1 (et)	1992-01-08	1994-11-22	Adenosiini derivaadid, nende valmistamise meetodid ja neid sisaldavad ravimvormid

Country Status (25)

Country	Link
US (2)	US5229505A (de)
EP (1)	EP0623138B1 (de)
JP (1)	JP3224542B2 (de)
KR (1)	KR100232672B1 (de)
AT (1)	ATE153342T1 (de)
AU (1)	AU661894B2 (de)
CA (1)	CA2127472C (de)
CZ (1)	CZ289047B6 (de)
DE (1)	DE69219901T2 (de)
DK (1)	DK0623138T3 (de)
EE (1)	EE03087B1 (de)
ES (1)	ES2105285T3 (de)
FI (1)	FI106205B (de)
FR (1)	FR2685918B1 (de)
GE (1)	GEP19981357B (de)
GR (1)	GR3024386T3 (de)
HU (1)	HU221304B1 (de)
LV (1)	LV11899B (de)
MD (1)	MD502G2 (de)
NZ (1)	NZ246904A (de)
RU (1)	RU2129560C1 (de)
SK (1)	SK282205B6 (de)
TW (1)	TW254945B (de)
UA (1)	UA44221C2 (de)
WO (1)	WO1993014102A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2685918B1 (fr) *	1992-01-08	1995-06-23	Union Pharma Scient Appl	Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.
FR2714907B1 (fr) *	1994-01-07	1996-03-29	Union Pharma Scient Appl	Nouveaux dérivés de l'Adénosine, leurs procédés de préparation, compositions pharmaceutiques les contenant.
WO1995018817A1 (fr) *	1994-01-07	1995-07-13	Laboratoires Upsa	Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant
TW528755B (en)	1996-12-24	2003-04-21	Glaxo Group Ltd	2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
FR2772271B1 (fr) *	1997-12-11	2000-09-01	Union Pharma Scient Appl	Nouvelle association pharmaceutique a activite analgesique
YU44900A (sh)	1998-01-31	2003-01-31	Glaxo Group Limited	Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
US6495528B1 (en)	1998-06-23	2002-12-17	Smithkline Beecham Corporation	2-(Purin -9-yl)-tetrahydrofuran-3,4-diol derivatives
JP2002173427A (ja) *	1998-09-01	2002-06-21	Yamasa Shoyu Co Ltd	眼疾患治療用医薬組成物
DE19924818A1 (de)	1999-05-29	2000-11-30	Bayer Ag	Substituierte Phenylcyclohexancarbonsäureamide
EP1229901B1 (de) *	1999-11-17	2009-03-18	Boston Scientific Limited	Miniaturisierte vorrichtungen zur abgabe von molekülen in einer trägerflüssigkeit
AU2001278708A1 (en) *	2000-09-08	2002-03-22	Toa Eiyo Ltd.	Adenosine derivatives and use thereof
EP1352910A1 (de) *	2002-04-10	2003-10-15	Grünenthal GmbH	Neue Analoga von Nitrobenzylthioinosine
PE20060272A1 (es)	2004-05-24	2006-05-22	Glaxo Group Ltd	(2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
GB0514809D0 (en)	2005-07-19	2005-08-24	Glaxo Group Ltd	Compounds
US12261115B2 (en)	2021-01-27	2025-03-25	Taiwan Semiconductor Manufacturing Company, Ltd.	Semiconductor devices and methods of manufacturing thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE788958A (fr) *	1971-09-18	1973-03-19	Schering Ag	Derives d'adenosine et leur procede de preparation
US4167565A (en) *	1976-11-08	1979-09-11	Abbott Laboratories	Adenosine-5'-carboxamides and method of use
US5310731A (en) *	1984-06-28	1994-05-10	Whitby Research, Inc.	N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
US4755594A (en) *	1986-01-31	1988-07-05	Warner-Lambert Company	N6 -substituted adenosines
JPH0696534B2 (ja) *	1986-04-25	1994-11-30	ヘキストジヤパン株式会社	抗痴呆剤
AU8276187A (en) *	1986-10-31	1988-05-25	Warner-Lambert Company	Selected n6-substituted adenosines having selective a2 binding activity
WO1988003148A2 (en) *	1986-10-31	1988-05-05	Warner-Lambert Company	Heteroaromatic derivatives of adenoside
IL84414A0 (en) *	1986-11-14	1988-04-29	Ciba Geigy Ag	N9-cyclopentyl-substituted adenine derivatives
SU1661367A1 (ru) *	1988-11-01	1991-07-07	Всесоюзный научно-исследовательский институт по креплению скважин и буровым растворам	Способ гидрофобизации тампонажных материалов
ES2095960T3 (es) *	1990-09-25	1997-03-01	Rhone Poulenc Rorer Int	Compuestos que tienen propiedades antihipertensivas y antiisquemicas.
FR2685918B1 (fr) *	1992-01-08	1995-06-23	Union Pharma Scient Appl	Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.

1992
- 1992-01-08 FR FR9200138A patent/FR2685918B1/fr not_active Expired - Lifetime
- 1992-02-07 US US07/832,576 patent/US5229505A/en not_active Expired - Lifetime
- 1992-12-29 NZ NZ246904A patent/NZ246904A/en not_active IP Right Cessation
- 1992-12-29 HU HU9402040A patent/HU221304B1/hu unknown
- 1992-12-29 RU RU94039545A patent/RU2129560C1/ru active
- 1992-12-29 KR KR1019940702365A patent/KR100232672B1/ko not_active Expired - Lifetime
- 1992-12-29 JP JP51218093A patent/JP3224542B2/ja not_active Expired - Lifetime
- 1992-12-29 DE DE69219901T patent/DE69219901T2/de not_active Expired - Lifetime
- 1992-12-29 SK SK818-94A patent/SK282205B6/sk not_active IP Right Cessation
- 1992-12-29 UA UA94005387A patent/UA44221C2/uk unknown
- 1992-12-29 GE GEAP19922541A patent/GEP19981357B/en unknown
- 1992-12-29 EP EP93914481A patent/EP0623138B1/de not_active Expired - Lifetime
- 1992-12-29 AT AT93914481T patent/ATE153342T1/de active
- 1992-12-29 US US08/256,081 patent/US5480983A/en not_active Expired - Lifetime
- 1992-12-29 ES ES93914481T patent/ES2105285T3/es not_active Expired - Lifetime
- 1992-12-29 DK DK93914481.2T patent/DK0623138T3/da active
- 1992-12-29 CA CA002127472A patent/CA2127472C/en not_active Expired - Lifetime
- 1992-12-29 AU AU34550/93A patent/AU661894B2/en not_active Expired
- 1992-12-29 CZ CZ19941643A patent/CZ289047B6/cs not_active IP Right Cessation
- 1992-12-29 WO PCT/FR1992/001241 patent/WO1993014102A1/fr not_active Ceased
1993
- 1993-01-07 TW TW082100078A patent/TW254945B/zh not_active IP Right Cessation
1994
- 1994-07-06 FI FI943222A patent/FI106205B/fi not_active IP Right Cessation
- 1994-11-22 EE EE9400381A patent/EE03087B1/xx unknown
- 1994-12-30 MD MD95-0111A patent/MD502G2/ro active IP Right Grant
1997
- 1997-06-25 LV LVP-97-128A patent/LV11899B/lv unknown
- 1997-08-07 GR GR970402030T patent/GR3024386T3/el unknown

Also Published As

Publication number	Publication date
MD502F1 (en)	1996-03-29
SK81894A3 (en)	1995-04-12
HU9402040D0 (en)	1994-09-28
KR100232672B1 (ko)	1999-12-01
JP3224542B2 (ja)	2001-10-29
ATE153342T1 (de)	1997-06-15
GR3024386T3 (en)	1997-11-28
AU3455093A (en)	1993-08-03
EP0623138A1 (de)	1994-11-09
DK0623138T3 (da)	1997-12-15
DE69219901D1 (de)	1997-06-26
CZ289047B6 (cs)	2001-10-17
UA44221C2 (uk)	2002-02-15
GEP19981357B (en)	1998-08-25
EP0623138B1 (de)	1997-05-21
RU94039545A (ru)	1997-04-27
JPH07502738A (ja)	1995-03-23
ES2105285T3 (es)	1997-10-16
LV11899A (lv)	1997-12-20
FR2685918A1 (fr)	1993-07-09
TW254945B (de)	1995-08-21
AU661894B2 (en)	1995-08-10
MD502G2 (ro)	1996-11-30
FI943222A0 (fi)	1994-07-06
US5229505A (en)	1993-07-20
FI106205B (fi)	2000-12-15
US5480983A (en)	1996-01-02
SK282205B6 (sk)	2001-12-03
FI943222L (fi)	1994-08-18
HUT68095A (en)	1995-05-29
NZ246904A (en)	1995-04-27
CA2127472C (en)	2003-11-18
DE69219901T2 (de)	1997-11-13
CA2127472A1 (en)	1993-07-22
WO1993014102A1 (fr)	1993-07-22
FR2685918B1 (fr)	1995-06-23
CZ164394A3 (en)	1995-02-15
HU221304B1 (en)	2002-09-28
RU2129560C1 (ru)	1999-04-27
LV11899B (lv)	1998-03-20

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231

Publication	Publication Date	Title
ATE113029T1 (de)	1994-11-15	Hustenstillendes und schleimregulierendes mittel, verfahren zu seiner herstellung und dieses enthaltende pharmazeutische zusammensetzungen.
DE69622031D1 (de)	2002-08-01	INDOLDERIVATE ALS cGMP-PDE INHIBITOREN
IL108520A0 (en)	1994-05-30	Imidazopyridine derivatives, processes for the preparation thereof, and pharmaceutical compositions containing them
GR3024386T3 (en)	1997-11-28	New adenosine derivatives, preparation methods and pharmaceutical compositions containing them.
ES8207169A1 (es)	1982-09-01	Un procedimiento para la preparacion de nuevos derivados de piperazinilquinazolina y de homopiperazinilquinazolina hi- pertensora con acticidad.
FR2681784B1 (fr)	1995-06-09	Composition dermatologique et/ou cosmetologique contenant des retinouides et utilisation de nouveaux retinouides.
FI940696A0 (fi)	1994-02-15	Uudet pyratsiinijohdannaiset, niiden valmistus ja käyttö
TR200000153T2 (tr)	2000-07-21	İl-5 inhibite eden 6-azaurasil türevleri.
GR3020330T3 (en)	1996-09-30	Novel bicyclic pyrimidine compounds, method for preparing same and pharmaceutical compositions containing said compounds.
KR950700287A (ko)	1995-01-16	스테로이드 5알파-리덕타아제 억제제로서의 인돌 유도체(Indole Derivatives as Steroid 5 Alpha-Reductase Inhibitors)
IL97277A0 (en)	1992-05-25	Beta-phenylisoserine derivative,and its preparation and application
DE69330601D1 (de)	2001-09-20	Serotoninergische ergolin derivate
MX9303605A (es)	1993-12-01	Derivados de azabicicloheptano n-substituidas, su obtencion y uso.
IL108288A0 (en)	1994-04-12	Pyrrolidine derivatives, their preparation and medicaments containing them
TW261605B (de)	1995-11-01
IL107520A0 (en)	1994-02-27	Substituted ortho-ethenylphenylacetic acid derivatives and pharmaceutical compositions containing them
ES2087567T3 (es)	1996-07-16	Derivados antibioticos de 7'-amino-naftazarina.
MX9303607A (es)	1994-04-29	Derivados de azabicicloheptano sustituidos, su obtencion y uso.
HU901631D0 (en)	1990-06-28	Process for the preparation of thienyl-piperazine derivatives and pharmaceutical compositions containing them