EE04054B1 - Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim - Google Patents

Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim

Info

Publication number: EE04054B1
Authority: EE; Estonia
Prior art keywords: medicaments; manufacture; tetrazole derivatives; medicaments containing; tetrazole
Prior art date: 1997-07-25

Application number

EEP200000033A

Other languages

English (en)

Estonian (et)

Inventor

Amschler Hermann

Flockerzi Dieter

Ulrich Wolf-R�diger

B�r Thomas

Martin Thomas

Schudt Christian

Hatzelmann Armin

Beume Rolf

H�fner Dietrich

Boss Hildegard

Kley Hans-Peter

Gutterer Beate

Original Assignee

Byk Gulden Lomberg Chemische Fabrik Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-25

Filing date

1998-07-18

Publication date

2003-06-16

1998-07-18 Application filed by Byk Gulden Lomberg Chemische Fabrik Gmbh filed Critical Byk Gulden Lomberg Chemische Fabrik Gmbh

2000-10-16 Publication of EE200000033A publication Critical patent/EE200000033A/xx

2003-06-16 Publication of EE04054B1 publication Critical patent/EE04054B1/xx

Links

239000003814 drug Substances 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title 1
150000003536 tetrazoles Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Immunology (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Cephalosporin Compounds (AREA)

EEP200000033A 1997-07-25 1998-07-18 Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim EE04054B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97112792		1997-07-25
PCT/EP1998/004477 WO1999005111A1 (en)	1997-07-25	1998-07-18	Novel tetrazole derivatives

Publications (2)

Publication Number	Publication Date
EE200000033A EE200000033A (et)	2000-10-16
EE04054B1 true EE04054B1 (et)	2003-06-16

Family

ID=8227116

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200000033A EE04054B1 (et)	1997-07-25	1998-07-18	Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim

Country Status (17)

Country	Link
US (1)	US6410551B1 (cs)
EP (1)	EP0998460B1 (cs)
JP (1)	JP2001510825A (cs)
AT (1)	ATE260899T1 (cs)
AU (1)	AU753615B2 (cs)
CA (1)	CA2297923A1 (cs)
CZ (1)	CZ293725B6 (cs)
DE (1)	DE69822162T2 (cs)
DK (1)	DK0998460T3 (cs)
EE (1)	EE04054B1 (cs)
ES (1)	ES2217575T3 (cs)
HU (1)	HUP0002510A3 (cs)
IL (1)	IL133824A (cs)
PL (1)	PL190685B1 (cs)
PT (1)	PT998460E (cs)
SI (1)	SI0998460T1 (cs)
WO (1)	WO1999005111A1 (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EE05105B1 (et) *	1999-01-15	2008-12-15	Byk Gulden Lomberg Chemische Fabrik Gmbh	Fenlfenantridiinid, nende kasutamine ravimite valmistamiseks ning neid sisaldav ravim
AU2107700A (en)	1999-01-15	2000-08-01	Byk Gulden Lomberg Chemische Fabrik Gmbh	Phenanthridine-n-oxides with pde-iv inhibiting activity
EP1147103B1 (en)	1999-01-15	2005-05-04	ALTANA Pharma AG	Phenantrhridine-n-oxides with pde-iv inhibiting activity
DE60025327T2 (de)	1999-01-15	2006-08-24	Altana Pharma Ag	6-arylphenanthridine mit pde-iv hemmender wirkung
ATE356810T1 (de)	1999-01-15	2007-04-15	Altana Pharma Ag	Polysubstituted 6-phenylphenanthridines mit pde- iv hemmender wirkung
PL200923B1 (pl)	1999-08-21	2009-02-27	Nycomed Gmbh	Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu
WO2001051470A1 (en)	2000-01-11	2001-07-19	Byk Gulden Lomberg Chemische Fabrik Gmbh	Phenanthridine-n-oxides
AU2001267589A1 (en) *	2000-07-14	2002-01-30	Byk Gulden Lomberg Chemische Fabrik G.M.B.H.	Cycloalkyl - or cycloalkylmethyl-substituted 6-phenylphenanthridines
WO2002005616A1 (en) *	2000-07-14	2002-01-24	Altana Pharma Ag	Novel 6-phenylphenanthridines
AU2001269126A1 (en) *	2000-07-14	2002-01-30	Byk Gulden Lomberg Chemische Fabrik G.M.B.H.	Phenanthridine n-oxides
SI1303506T1 (en) *	2000-07-14	2005-06-30	Altana Pharma Ag	6-heteroarylphenanthridines
CA2495597A1 (en) *	2002-08-17	2004-03-04	Altana Pharma Ag	Novel phenanthridines
CA2496459C (en)	2002-08-29	2013-06-25	Altana Pharma Ag	3-hydroxy-6-phenylphenanthridines as pde-4 inhibitors
AU2003255493B8 (en) *	2002-08-29	2009-03-26	Takeda Gmbh	2-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors
ES2307974T3 (es)	2002-11-20	2008-12-01	Pfizer Products Inc.	Procedimiento de preparacion de acido indan-1,2-dicarboxilico.
JP2006522151A (ja)	2003-04-01	2006-09-28	アプライドリサーチシステムズエーアールエスホールディングナームロゼフェンノートシャップ	不妊症におけるホスホジエステラーゼ阻害剤
EP1658270A1 (en) *	2003-07-31	2006-05-24	ALTANA Pharma AG	Novel 6-phenylphenantridines
JP2007500686A (ja) *	2003-07-31	2007-01-18	アルタナ　ファルマ　アクチエンゲゼルシャフト	新規の６−フェニルフェナントリジン
EP1720835B1 (en) *	2004-02-18	2012-12-12	Nycomed GmbH	Novel guanidinyl-substituted hydroxy-6-phenylphenanthridines as effective phosphodiesterase (pde) 4 inhibitors
PL2589599T4 (pl)	2004-03-03	2015-06-30	Takeda Gmbh	Nowe hydroksy-6-heteroarylofenantrydyny i ich zastosowanie jako inhibitorów PDE4
AR049419A1 (es) *	2004-03-03	2006-08-02	Altana Pharma Ag	Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo
AU2005220034A1 (en) *	2004-03-09	2005-09-15	Nycomed Gmbh	Novel isoamido-substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors
MXPA06009892A (es) *	2004-03-10	2007-03-01	Altana Pharma Ag	Nuevas hidroxi-6-fenilfenantridinas sustituidas con amido y su uso como inhibidores de la fosfodiesterasa tipo 4 (pde4).
BRPI0508471A8 (pt) *	2004-03-10	2019-01-15	Altana Pharma Ag	compostos de hidróxi-6-fenilfenantidinas substituídas por difluoroetóxi, composição farmacêutica e uso para a produção dos mesmos
CA2558390A1 (en) *	2004-03-10	2005-09-22	Altana Pharma Ag	Novel thio-containing hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors
ES2337083T3 (es)	2005-03-02	2010-04-20	Nycomed Gmbh	(2r,4ar,10br)-6-(2,6-dimetoxipiridin-3-il)-9-exoti-8-metoxi-1,2,3,4,4a,10b-hexahidrofenantridin-2-ol, sal de hc1.
KR101178674B1 (ko)	2007-10-04	2012-08-30	에프. 호프만-라 로슈 아게	사이클로프로필 아릴 아마이드 유도체 및 이의 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9027055D0 (en) *	1990-12-13	1991-02-06	Sandoz Ltd	Organic compounds
EE03523B1 (et) *	1996-01-31	2001-10-15	Byk Gulden Lomberg Chemische Fabrik Gmbh	Fenantridiinid, neid sisaldavad ravimid ja nende kasutamine
CA2250569C (en) *	1996-03-26	2005-05-10	Byk Gulden Lomberg Chemische Fabrik Gmbh	Novel phenanthridines substituted in the 6 position

1998
- 1998-07-18 AU AU89770/98A patent/AU753615B2/en not_active Ceased
- 1998-07-18 PL PL98338339A patent/PL190685B1/pl not_active IP Right Cessation
- 1998-07-18 AT AT98941361T patent/ATE260899T1/de not_active IP Right Cessation
- 1998-07-18 DE DE69822162T patent/DE69822162T2/de not_active Expired - Fee Related
- 1998-07-18 IL IL13382498A patent/IL133824A/xx not_active IP Right Cessation
- 1998-07-18 EE EEP200000033A patent/EE04054B1/xx not_active IP Right Cessation
- 1998-07-18 US US09/446,703 patent/US6410551B1/en not_active Expired - Fee Related
- 1998-07-18 CZ CZ2000282A patent/CZ293725B6/cs not_active IP Right Cessation
- 1998-07-18 WO PCT/EP1998/004477 patent/WO1999005111A1/en not_active Ceased
- 1998-07-18 EP EP98941361A patent/EP0998460B1/en not_active Expired - Lifetime
- 1998-07-18 SI SI9830644T patent/SI0998460T1/xx unknown
- 1998-07-18 ES ES98941361T patent/ES2217575T3/es not_active Expired - Lifetime
- 1998-07-18 CA CA002297923A patent/CA2297923A1/en not_active Abandoned
- 1998-07-18 DK DK98941361T patent/DK0998460T3/da active
- 1998-07-18 PT PT98941361T patent/PT998460E/pt unknown
- 1998-07-18 HU HU0002510A patent/HUP0002510A3/hu unknown
- 1998-07-18 JP JP2000504110A patent/JP2001510825A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
PL190685B1 (pl)	2005-12-30
DK0998460T3 (da)	2004-07-05
DE69822162T2 (de)	2005-01-27
JP2001510825A (ja)	2001-08-07
ES2217575T3 (es)	2004-11-01
PT998460E (pt)	2004-07-30
IL133824A (en)	2005-12-18
EP0998460B1 (en)	2004-03-03
US6410551B1 (en)	2002-06-25
HUP0002510A3 (en)	2002-10-28
SI0998460T1 (en)	2004-08-31
AU753615B2 (en)	2002-10-24
AU8977098A (en)	1999-02-16
PL338339A1 (en)	2000-10-23
CZ2000282A3 (cs)	2000-08-16
CZ293725B6 (cs)	2004-07-14
ATE260899T1 (de)	2004-03-15
DE69822162D1 (de)	2004-04-08
WO1999005111A1 (en)	1999-02-04
EP0998460A1 (en)	2000-05-10
HUP0002510A2 (hu)	2000-12-28
EE200000033A (et)	2000-10-16
IL133824A0 (en)	2001-04-30
CA2297923A1 (en)	1999-02-04

Legal Events

Date	Code	Title	Description
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2010-04-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20090718

Publication	Publication Date	Title
EE03523B1 (et)	2001-10-15	Fenantridiinid, neid sisaldavad ravimid ja nende kasutamine
IL133824A0 (en)	2001-04-30	Tetrazole derivatives, medicaments containing same and use thereof
EE05105B1 (et)	2008-12-15	Fenlfenantridiinid, nende kasutamine ravimite valmistamiseks ning neid sisaldav ravim
ES2189235T3 (es)	2003-07-01	6-fenilfenantridinas sustituidas.
DK0889886T3 (da)	2003-01-20	Hidtil ukendte, i 6-stilling substituerede phenanthridiner
TR200002953T2 (tr)	2001-01-22	İki halkalı hidroksamik asit türevleri
TR200002860T2 (tr)	2000-12-21	Bir antiviral benzimidazol terkibin yeni kristal formları.
TR200200795T2 (tr)	2002-07-22	5-HT1B antagonistleri olarak piperazin türevleri
EE200000335A (et)	2001-10-15	Dihüdrobensofuraanid, nende kasutamine ravimite valmistamiseks ning neid sisaldavad ravimid
EE9900450A (et)	2000-04-17	Tetrahüdropüridoühendid, neid sisaldav ravim ja nende kasutamine
DE60025327D1 (de)	2006-03-30	6-arylphenanthridine mit pde-iv hemmender wirkung
TR200000637T2 (tr)	2000-07-21	Benzoksazin ve benzotiazin türevleri ve bunların ilaçlarda kullanımı.
AU758194C (en)	2004-04-08	Novel benzimidazoles and benzoxazoles
NZ331374A (en)	2000-01-28	Phenanthridine compounds and pharmaceutical compositions thereof