EE04054B1 - Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim - Google Patents

Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim

Info

Publication number: EE04054B1
Authority: EE; Estonia
Prior art keywords: medicaments; manufacture; tetrazole derivatives; medicaments containing; tetrazole
Prior art date: 1997-07-25

Application number

EEP200000033A

Other languages

English (en)

Estonian (et)

Inventor

Amschler Hermann

Flockerzi Dieter

Ulrich Wolf-R�diger

B�r Thomas

Martin Thomas

Schudt Christian

Hatzelmann Armin

Beume Rolf

H�fner Dietrich

Boss Hildegard

Kley Hans-Peter

Gutterer Beate

Original Assignee

Byk Gulden Lomberg Chemische Fabrik Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-25

Filing date

1998-07-18

Publication date

2003-06-16

1998-07-18 Application filed by Byk Gulden Lomberg Chemische Fabrik Gmbh filed Critical Byk Gulden Lomberg Chemische Fabrik Gmbh

2000-10-16 Publication of EE200000033A publication Critical patent/EE200000033A/xx

2003-06-16 Publication of EE04054B1 publication Critical patent/EE04054B1/xx

Links

239000003814 drug Substances 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title 1
150000003536 tetrazoles Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Cardiology (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Otolaryngology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

EEP200000033A 1997-07-25 1998-07-18 Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim EE04054B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97112792		1997-07-25
PCT/EP1998/004477 WO1999005111A1 (en)	1997-07-25	1998-07-18	Novel tetrazole derivatives

Publications (2)

Publication Number	Publication Date
EE200000033A EE200000033A (et)	2000-10-16
EE04054B1 true EE04054B1 (et)	2003-06-16

Family

ID=8227116

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200000033A EE04054B1 (et)	1997-07-25	1998-07-18	Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim

Country Status (17)

Country	Link
US (1)	US6410551B1 (cs)
EP (1)	EP0998460B1 (cs)
JP (1)	JP2001510825A (cs)
AT (1)	ATE260899T1 (cs)
AU (1)	AU753615B2 (cs)
CA (1)	CA2297923A1 (cs)
CZ (1)	CZ293725B6 (cs)
DE (1)	DE69822162T2 (cs)
DK (1)	DK0998460T3 (cs)
EE (1)	EE04054B1 (cs)
ES (1)	ES2217575T3 (cs)
HU (1)	HUP0002510A3 (cs)
IL (1)	IL133824A (cs)
PL (1)	PL190685B1 (cs)
PT (1)	PT998460E (cs)
SI (1)	SI0998460T1 (cs)
WO (1)	WO1999005111A1 (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2241571T3 (es) *	1999-01-15	2005-11-01	Altana Pharma Ag	N-oxidos de fenantrinida con actividad inhividora de pde-iv.
CA2360386A1 (en)	1999-01-15	2000-07-20	Beate Gutterer	Polysubstituted 6-phenylphenanthridines with pde-iv inhibiting activity
DE60020079T2 (de)	1999-01-15	2006-01-19	Altana Pharma Ag	Phenanthridin-N-oxide mit PDE-IV-hemmender Wirkung
WO2000042019A1 (en)	1999-01-15	2000-07-20	Byk Gulden Lomberg Chemische Fabrik Gmbh	6-arylphenanthridines with pde-iv inhibiting activity
TR200501553T2 (tr)	1999-01-15	2005-06-21	Altana Pharma Ag	PDE-IV inhibe edici aktivitesi olan fenilfenantridinler
CA2715683A1 (en)	1999-08-21	2001-03-01	Nycomed Gmbh	Synergistic combination
WO2001051470A1 (en)	2000-01-11	2001-07-19	Byk Gulden Lomberg Chemische Fabrik Gmbh	Phenanthridine-n-oxides
WO2002005616A1 (en) *	2000-07-14	2002-01-24	Altana Pharma Ag	Novel 6-phenylphenanthridines
WO2002006239A1 (en) *	2000-07-14	2002-01-24	Altana Pharma Ag	Phenanthridine n-oxides
WO2002006238A1 (en) *	2000-07-14	2002-01-24	Altana Pharma Ag	Cycloalkyl - or cycloalkylmethyl-substituted 6-phenylphenanthridines
ES2236288T3 (es)	2000-07-14	2005-07-16	Altana Pharma Ag	6-heteroarilfenantridinas.
CA2495597A1 (en) *	2002-08-17	2004-03-04	Altana Pharma Ag	Novel phenanthridines
JP4587294B2 (ja)	2002-08-29	2010-11-24	ニコメッドゲゼルシャフトミットベシュレンクテルハフツング	Ｐｄｅ４インヒビターとしての２−ヒドロキシ−６−フェニルフェナントリジン
ATE353217T1 (de) *	2002-08-29	2007-02-15	Altana Pharma Ag	3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren
MXPA05005366A (es)	2002-11-20	2005-08-03	Pfizer Prod Inc	Un metodo para preparar acido indano-1,3-dicarboxilico.
US7153824B2 (en)	2003-04-01	2006-12-26	Applied Research Systems Ars Holding N.V.	Inhibitors of phosphodiesterases in infertility
EP1658270A1 (en) *	2003-07-31	2006-05-24	ALTANA Pharma AG	Novel 6-phenylphenantridines
CA2533636A1 (en) *	2003-07-31	2005-02-10	Altana Pharma Ag	Novel 6-phenylphenanthridines
CA2556086C (en) *	2004-02-18	2014-04-01	Altana Pharma Ag	Novel guanidinyl-substituted hydroxy-6-phenylphenenthridines as effective phosphodiesterase (pde) 4 inhibitors
PL2589599T4 (pl)	2004-03-03	2015-06-30	Takeda Gmbh	Nowe hydroksy-6-heteroarylofenantrydyny i ich zastosowanie jako inhibitorów PDE4
AR049419A1 (es) *	2004-03-03	2006-08-02	Altana Pharma Ag	Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo
AU2005220034A1 (en) *	2004-03-09	2005-09-15	Nycomed Gmbh	Novel isoamido-substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors
EP1725534A1 (en) *	2004-03-10	2006-11-29	Altana Pharma AG	Novel amido-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors
CA2558390A1 (en) *	2004-03-10	2005-09-22	Altana Pharma Ag	Novel thio-containing hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors
WO2005085203A1 (en) *	2004-03-10	2005-09-15	Altana Pharma Ag	Novel difluoroethoxy-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors
PL1856093T3 (pl) *	2005-03-02	2010-05-31	Takeda Gmbh	Chlorowodorek (2R,4aR,10bR)-6-(2,6-dimetoksy-pirydyn-3-ylo)-9-etoksy-8-metoksy-1,2,3,4,4a,10b-heksahydrofenantrydyn-2-olu
ES2460897T3 (es)	2007-10-04	2014-05-14	F. Hoffmann-La Roche Ag	Derivados de ciclopropil aril amida y usos de los mismos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9027055D0 (en) *	1990-12-13	1991-02-06	Sandoz Ltd	Organic compounds
BR9707233A (pt) *	1996-01-31	1999-07-20	Byk Gulden Lomberg Chem Fab	Fenantridinas
SI0889886T1 (en) *	1996-03-26	2003-02-28	Altana Pharma Ag	Novel phenanthridines substituted in the 6 position

1998
- 1998-07-18 PT PT98941361T patent/PT998460E/pt unknown
- 1998-07-18 AU AU89770/98A patent/AU753615B2/en not_active Ceased
- 1998-07-18 IL IL13382498A patent/IL133824A/xx not_active IP Right Cessation
- 1998-07-18 EE EEP200000033A patent/EE04054B1/xx not_active IP Right Cessation
- 1998-07-18 DK DK98941361T patent/DK0998460T3/da active
- 1998-07-18 ES ES98941361T patent/ES2217575T3/es not_active Expired - Lifetime
- 1998-07-18 US US09/446,703 patent/US6410551B1/en not_active Expired - Fee Related
- 1998-07-18 PL PL98338339A patent/PL190685B1/pl not_active IP Right Cessation
- 1998-07-18 WO PCT/EP1998/004477 patent/WO1999005111A1/en not_active Ceased
- 1998-07-18 DE DE69822162T patent/DE69822162T2/de not_active Expired - Fee Related
- 1998-07-18 HU HU0002510A patent/HUP0002510A3/hu unknown
- 1998-07-18 JP JP2000504110A patent/JP2001510825A/ja not_active Withdrawn
- 1998-07-18 SI SI9830644T patent/SI0998460T1/xx unknown
- 1998-07-18 EP EP98941361A patent/EP0998460B1/en not_active Expired - Lifetime
- 1998-07-18 CA CA002297923A patent/CA2297923A1/en not_active Abandoned
- 1998-07-18 AT AT98941361T patent/ATE260899T1/de not_active IP Right Cessation
- 1998-07-18 CZ CZ2000282A patent/CZ293725B6/cs not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT998460E (pt)	2004-07-30
IL133824A (en)	2005-12-18
EP0998460A1 (en)	2000-05-10
CZ2000282A3 (cs)	2000-08-16
DE69822162D1 (de)	2004-04-08
JP2001510825A (ja)	2001-08-07
IL133824A0 (en)	2001-04-30
HUP0002510A3 (en)	2002-10-28
CA2297923A1 (en)	1999-02-04
SI0998460T1 (en)	2004-08-31
PL338339A1 (en)	2000-10-23
HUP0002510A2 (hu)	2000-12-28
ATE260899T1 (de)	2004-03-15
US6410551B1 (en)	2002-06-25
CZ293725B6 (cs)	2004-07-14
EP0998460B1 (en)	2004-03-03
EE200000033A (et)	2000-10-16
AU8977098A (en)	1999-02-16
WO1999005111A1 (en)	1999-02-04
DE69822162T2 (de)	2005-01-27
ES2217575T3 (es)	2004-11-01
DK0998460T3 (da)	2004-07-05
AU753615B2 (en)	2002-10-24
PL190685B1 (pl)	2005-12-30

Legal Events

Date	Code	Title	Description
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2010-04-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20090718

Publication	Publication Date	Title
EE04054B1 (et)	2003-06-16	Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim
EE03523B1 (et)	2001-10-15	Fenantridiinid, neid sisaldavad ravimid ja nende kasutamine
EE05105B1 (et)	2008-12-15	Fenlfenantridiinid, nende kasutamine ravimite valmistamiseks ning neid sisaldav ravim
ES2189235T3 (es)	2003-07-01	6-fenilfenantridinas sustituidas.
DK0889886T3 (da)	2003-01-20	Hidtil ukendte, i 6-stilling substituerede phenanthridiner
TR200002953T2 (tr)	2001-01-22	İki halkalı hidroksamik asit türevleri
ATE269850T1 (de)	2004-07-15	3-thiocarbamoylpyrazol-derivate als pestiziden
PT1140944E (pt)	2004-01-30	Derivados de epotilona e sua utilizacao como agentes antitumorais
TR200002860T2 (tr)	2000-12-21	Bir antiviral benzimidazol terkibin yeni kristal formları.
TR200200795T2 (tr)	2002-07-22	5-HT1B antagonistleri olarak piperazin türevleri
BR9713338A (pt)	2000-05-09	Benzonaftiridinas como terapêuticos brÈnquicos.
EE200000335A (et)	2001-10-15	Dihüdrobensofuraanid, nende kasutamine ravimite valmistamiseks ning neid sisaldavad ravimid
EE9900450A (et)	2000-04-17	Tetrahüdropüridoühendid, neid sisaldav ravim ja nende kasutamine
DE60025327D1 (de)	2006-03-30	6-arylphenanthridine mit pde-iv hemmender wirkung
TR200000637T2 (tr)	2000-07-21	Benzoksazin ve benzotiazin türevleri ve bunların ilaçlarda kullanımı.
EE200000647A (et)	2002-06-17	Uudsed bensimidasoolid ja bensoksasoolid, nende kasutamine hingamisteede ja dermatooside raviks ette nähtud ravimite valmistamiseks ning neid sisaldav ravim
TR200100476T2 (tr)	2001-07-23	N-İkameli azabisikloheptan türevlerinin üretimleri ve kullanımları.