EE04261B1 - Aminoadamantaaniühendite kasutamine immunoregulaatoritena - Google Patents

Aminoadamantaaniühendite kasutamine immunoregulaatoritena

Info

Publication number
EE04261B1
EE04261B1 EE9800057A EE9800057A EE04261B1 EE 04261 B1 EE04261 B1 EE 04261B1 EE 9800057 A EE9800057 A EE 9800057A EE 9800057 A EE9800057 A EE 9800057A EE 04261 B1 EE04261 B1 EE 04261B1
Authority
EE
Estonia
Prior art keywords
aminoadamantane
immunoregulators
compounds
aminoadamantane compounds
neutrophils
Prior art date
Application number
EE9800057A
Other languages
English (en)
Estonian (et)
Other versions
EE9800057A (et
Inventor
F. Elstner Erich
Original Assignee
Merz + Co. Gmbh & Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz + Co. Gmbh & Co. filed Critical Merz + Co. Gmbh & Co.
Publication of EE9800057A publication Critical patent/EE9800057A/xx
Publication of EE04261B1 publication Critical patent/EE04261B1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/064Saccharomycetales, e.g. baker's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • AIDS & HIV (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EE9800057A 1995-08-25 1996-08-21 Aminoadamantaaniühendite kasutamine immunoregulaatoritena EE04261B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19531342A DE19531342B4 (de) 1995-08-25 1995-08-25 Verwendung von Aminoadamantan-Verbindungen als Immunregulatoren
PCT/EP1996/003678 WO1997007791A1 (en) 1995-08-25 1996-08-21 Use of aminoadamantane compounds as immunoregulators

Publications (2)

Publication Number Publication Date
EE9800057A EE9800057A (et) 1998-08-17
EE04261B1 true EE04261B1 (et) 2004-04-15

Family

ID=7770407

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800057A EE04261B1 (et) 1995-08-25 1996-08-21 Aminoadamantaaniühendite kasutamine immunoregulaatoritena

Country Status (21)

Country Link
US (2) US6172116B1 (cs)
EP (2) EP0845984B1 (cs)
JP (1) JPH11512093A (cs)
KR (1) KR100392986B1 (cs)
CN (1) CN1282452C (cs)
AT (1) ATE234083T1 (cs)
AU (1) AU718219B2 (cs)
CA (1) CA2230159C (cs)
CZ (1) CZ299356B6 (cs)
DE (3) DE19531342B4 (cs)
DK (1) DK0845984T3 (cs)
EE (1) EE04261B1 (cs)
ES (1) ES2193259T3 (cs)
GE (1) GEP19991779B (cs)
IL (1) IL123394A (cs)
MX (1) MX217078B (cs)
NO (1) NO319153B1 (cs)
RU (1) RU2219916C2 (cs)
UA (1) UA57711C2 (cs)
WO (1) WO1997007791A1 (cs)
ZA (1) ZA967137B (cs)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ543319A (en) * 1999-04-28 2007-06-29 Neurochem Int Ltd Compositions and methods for treating amyloidosis using sulphonate derivatives
RU2196575C2 (ru) * 1999-07-30 2003-01-20 Научно-исследовательский институт фармакологии РАМН Вещество, обладающее психостимулирующим и антиастеническим действием
US6444702B1 (en) 2000-02-22 2002-09-03 Neuromolecular, Inc. Aminoadamantane derivatives as therapeutic agents
RU2226391C2 (ru) * 2002-05-28 2004-04-10 Плотников Владимир Михайлович Средство для повышения активности нейтрофилов
RU2246482C2 (ru) * 2002-12-25 2005-02-20 ООО "Циклан" Способ получения гидрохлорида 1-амино-3,5-диметиладамантана
US7414076B2 (en) * 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US20070010573A1 (en) * 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
UA79908C2 (en) * 2004-06-24 2007-07-25 Olainfarm Joint Stock Company Application of polymeric salts 3,5-dimethyl-1-adamantilammonium as immunostimulative and interferonogenous agent
WO2006085149A2 (en) 2004-12-22 2006-08-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
KR101608445B1 (ko) 2006-10-12 2016-04-01 비에이치아이 리미티드 파트너쉽 3-아미노-1-프로판설폰산을 전달하기 위한 방법, 화합물, 조성물 및 비히클
KR101519280B1 (ko) * 2010-08-09 2015-05-11 시오노기세이야쿠가부시키가이샤 아미노아다만탄카르바메이트 유도체의 제조 방법
WO2017223402A1 (en) 2016-06-23 2017-12-28 Corium International, Inc. Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent
CA3031944A1 (en) 2016-07-27 2018-02-01 Corium International, Inc. Transdermal delivery systems with pharmacokinetics bioequivalent to oral delivery
US10945968B2 (en) 2016-07-27 2021-03-16 Corium, Inc. Memantine transdermal delivery systems
AU2017301928B2 (en) 2016-07-27 2023-04-06 Corium, LLC. Donepezil transdermal delivery system
US11173132B2 (en) 2017-12-20 2021-11-16 Corium, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3450761A (en) * 1967-03-30 1969-06-17 Sun Oil Co 1-aminoethyldimethyladamantane
DE4014672A1 (de) * 1990-05-08 1991-11-14 Werner E G Prof Dr Mueller Verwendung von adamantan-derivaten zur zytoprotektion von nicht-infizierten und virus-infizierten lymphozyten als auch anderen zelltypen

Also Published As

Publication number Publication date
UA57711C2 (uk) 2003-07-15
DE10399029I1 (de) 2004-01-08
EP0845984B1 (en) 2003-03-12
ZA967137B (en) 1997-03-12
IL123394A (en) 2004-07-25
WO1997007791A1 (en) 1997-03-06
IL123394A0 (en) 1998-09-24
DE69626650D1 (de) 2003-04-17
EP1293201A2 (en) 2003-03-19
MX9801496A (es) 1998-05-31
JPH11512093A (ja) 1999-10-19
US6255348B1 (en) 2001-07-03
EP0845984A1 (en) 1998-06-10
CN1198669A (zh) 1998-11-11
US6172116B1 (en) 2001-01-09
CN1282452C (zh) 2006-11-01
KR19990044096A (ko) 1999-06-25
DE69626650T2 (de) 2003-12-18
DK0845984T3 (da) 2003-06-23
DE19531342B4 (de) 2007-11-29
ES2193259T3 (es) 2003-11-01
EE9800057A (et) 1998-08-17
NO980793L (no) 1998-02-25
CA2230159A1 (en) 1997-03-06
AU6926396A (en) 1997-03-19
MX217078B (es) 2003-10-22
CZ299356B6 (cs) 2008-07-02
KR100392986B1 (ko) 2003-11-17
GEP19991779B (en) 1999-10-05
NO319153B1 (no) 2005-06-27
EP1293201A3 (en) 2003-05-21
RU2219916C2 (ru) 2003-12-27
ATE234083T1 (de) 2003-03-15
NO980793D0 (no) 1998-02-25
CZ52498A3 (cs) 1999-04-14
DE19531342A1 (de) 1997-02-27
AU718219B2 (en) 2000-04-13
CA2230159C (en) 2008-02-26

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20080821