EE04594B1 - 3-desoksüdesmükosiini derivaadid ja nende valmistamismeetod - Google Patents

3-desoksüdesmükosiini derivaadid ja nende valmistamismeetod

Info

Publication number: EE04594B1
Authority: EE; Estonia
Prior art keywords: desmycosin; derivatives; deoxydesmycosin; preparation; deoxy
Prior art date: 1999-05-03

Application number

EEP200100571A

Other languages

English (en)

Estonian (et)

Inventor

Narandja Amalija

Lopotar Nevenka

Djerek Marko

Pavlovic Drazen

Original Assignee

PLIVA, farmaceutska industrija, dionicko dru�tvo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-03

Filing date

2000-05-02

Publication date

2006-02-15

2000-05-02 Application filed by PLIVA, farmaceutska industrija, dionicko dru�tvo filed Critical PLIVA, farmaceutska industrija, dionicko dru�tvo

2003-02-17 Publication of EE200100571A publication Critical patent/EE200100571A/xx

2006-02-15 Publication of EE04594B1 publication Critical patent/EE04594B1/xx

Links

QRPHLEPFYLNRDA-NLGRAQRVSA-N 2-[(4r,5s,6s,7r,9r,11e,13e,15r,16r)-6-[(2r,3r,4s,5s,6r)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2r,3r,4r,5r,6r)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,1 Chemical compound O([C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@@H]1O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]1O QRPHLEPFYLNRDA-NLGRAQRVSA-N 0.000 abstract 3
238000006735 epoxidation reaction Methods 0.000 abstract 2
125000000466 oxiranyl group Chemical group 0.000 abstract 2
230000002829 reductive effect Effects 0.000 abstract 2
AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
238000005984 hydrogenation reaction Methods 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Peptides Or Proteins (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Steroid Compounds (AREA)

EEP200100571A 1999-05-03 2000-05-02 3-desoksüdesmükosiini derivaadid ja nende valmistamismeetod EE04594B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HR990129A HRP990129B1 (en)	1999-05-03	1999-05-03	New compounds of 3-deoxy-desmycosin class and process for the preparation thereof
PCT/HR2000/000012 WO2000066602A1 (en)	1999-05-03	2000-05-02	3-deoxy-desmycosin derivatives and process for their preparation

Publications (2)

Publication Number	Publication Date
EE200100571A EE200100571A (et)	2003-02-17
EE04594B1 true EE04594B1 (et)	2006-02-15

Family

ID=10946915

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200100571A EE04594B1 (et)	1999-05-03	2000-05-02	3-desoksüdesmükosiini derivaadid ja nende valmistamismeetod

Country Status (31)

Country	Link
US (1)	US6504035B1 (es)
EP (1)	EP1175428B1 (es)
JP (1)	JP2002543212A (es)
KR (1)	KR100679903B1 (es)
CN (1)	CN1191263C (es)
AT (1)	ATE238332T1 (es)
AU (1)	AU767549B2 (es)
BG (1)	BG106172A (es)
BR (1)	BR0010250A (es)
CA (1)	CA2368249A1 (es)
CZ (1)	CZ296455B6 (es)
DE (1)	DE60002314T2 (es)
DK (1)	DK1175428T3 (es)
EA (1)	EA004059B1 (es)
EE (1)	EE04594B1 (es)
ES (1)	ES2198302T3 (es)
GE (1)	GEP20032927B (es)
HK (1)	HK1050010A1 (es)
HR (1)	HRP990129B1 (es)
HU (1)	HUP0201140A3 (es)
IL (1)	IL145989A0 (es)
IS (1)	IS6117A (es)
MX (1)	MXPA01011089A (es)
NO (1)	NO320141B1 (es)
NZ (1)	NZ515280A (es)
PL (1)	PL352027A1 (es)
SK (1)	SK283967B6 (es)
TR (1)	TR200103146T2 (es)
UA (1)	UA66927C2 (es)
WO (1)	WO2000066602A1 (es)
ZA (1)	ZA200108482B (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8405087D0 (en) *	1984-02-27	1984-04-04	Omura S	Antibiotic
GB2171991B (en) *	1985-03-06	1988-08-17	Satoshi Omura	Novel macrolide derivatives, process for preparing same, and antibacterial compositions thereof
JPS62221695A (ja) *	1986-03-24	1987-09-29	Microbial Chem Res Found	タイロシンオキシム誘導体およびその製造法
SI8710674B (sl) *	1987-04-14	1998-06-30	Pliva	Postopek za pripravo 10,11,12,13-tetrahidro derivatov tilozina
JPH05230094A (ja) *	1992-02-26	1993-09-07	Asahi Chem Ind Co Ltd	マイシナマイシン誘導体

1999
- 1999-05-03 HR HR990129A patent/HRP990129B1/xx not_active IP Right Cessation
2000
- 2000-05-02 GE GEAP20006228A patent/GEP20032927B/en unknown
- 2000-05-02 DK DK00920939T patent/DK1175428T3/da active
- 2000-05-02 CA CA002368249A patent/CA2368249A1/en not_active Abandoned
- 2000-05-02 ES ES00920939T patent/ES2198302T3/es not_active Expired - Lifetime
- 2000-05-02 TR TR2001/03146T patent/TR200103146T2/xx unknown
- 2000-05-02 UA UA2001118220A patent/UA66927C2/uk unknown
- 2000-05-02 PL PL00352027A patent/PL352027A1/xx not_active IP Right Cessation
- 2000-05-02 EP EP00920939A patent/EP1175428B1/en not_active Expired - Lifetime
- 2000-05-02 IL IL14598900A patent/IL145989A0/xx unknown
- 2000-05-02 CZ CZ20013821A patent/CZ296455B6/cs not_active IP Right Cessation
- 2000-05-02 EA EA200101169A patent/EA004059B1/ru not_active IP Right Cessation
- 2000-05-02 KR KR1020017014045A patent/KR100679903B1/ko not_active Expired - Fee Related
- 2000-05-02 HU HU0201140A patent/HUP0201140A3/hu unknown
- 2000-05-02 SK SK1568-2001A patent/SK283967B6/sk not_active IP Right Cessation
- 2000-05-02 AT AT00920939T patent/ATE238332T1/de not_active IP Right Cessation
- 2000-05-02 CN CNB008071519A patent/CN1191263C/zh not_active Expired - Fee Related
- 2000-05-02 WO PCT/HR2000/000012 patent/WO2000066602A1/en not_active Ceased
- 2000-05-02 AU AU41349/00A patent/AU767549B2/en not_active Ceased
- 2000-05-02 BR BR0010250-4A patent/BR0010250A/pt not_active IP Right Cessation
- 2000-05-02 MX MXPA01011089A patent/MXPA01011089A/es active IP Right Grant
- 2000-05-02 NZ NZ515280A patent/NZ515280A/xx unknown
- 2000-05-02 EE EEP200100571A patent/EE04594B1/xx not_active IP Right Cessation
- 2000-05-02 DE DE60002314T patent/DE60002314T2/de not_active Expired - Lifetime
- 2000-05-02 US US09/959,692 patent/US6504035B1/en not_active Expired - Fee Related
- 2000-05-02 HK HK03100593.8A patent/HK1050010A1/zh unknown
- 2000-05-02 JP JP2000615631A patent/JP2002543212A/ja active Pending
2001
- 2001-10-16 ZA ZA200108482A patent/ZA200108482B/xx unknown
- 2001-10-19 IS IS6117A patent/IS6117A/is unknown
- 2001-11-01 NO NO20015347A patent/NO320141B1/no unknown
- 2001-12-03 BG BG106172A patent/BG106172A/bg unknown

Also Published As

Publication number	Publication date
HRP990129A2 (en)	2001-12-31
DE60002314D1 (de)	2003-05-28
IS6117A (is)	2001-10-19
AU767549B2 (en)	2003-11-13
WO2000066602A9 (en)	2001-12-20
GEP20032927B (en)	2003-03-25
KR20020007396A (ko)	2002-01-26
EP1175428A1 (en)	2002-01-30
WO2000066602A1 (en)	2000-11-09
DE60002314T2 (de)	2004-03-04
CZ296455B6 (cs)	2006-03-15
EP1175428B1 (en)	2003-04-23
NO20015347L (no)	2001-11-01
TR200103146T2 (tr)	2002-05-21
HUP0201140A3 (en)	2003-03-28
ATE238332T1 (de)	2003-05-15
BG106172A (bg)	2002-07-31
NZ515280A (en)	2002-12-20
BR0010250A (pt)	2002-02-19
CN1362963A (zh)	2002-08-07
EA004059B1 (ru)	2003-12-25
IL145989A0 (en)	2002-07-25
ZA200108482B (en)	2002-12-24
MXPA01011089A (es)	2002-07-22
UA66927C2 (uk)	2004-06-15
CN1191263C (zh)	2005-03-02
SK15682001A3 (sk)	2002-06-04
NO320141B1 (no)	2005-10-31
US6504035B1 (en)	2003-01-07
HRP990129B1 (en)	2003-10-31
CA2368249A1 (en)	2000-11-09
ES2198302T3 (es)	2004-02-01
SK283967B6 (sk)	2004-06-08
PL352027A1 (en)	2003-07-28
KR100679903B1 (ko)	2007-02-28
AU4134900A (en)	2000-11-17
JP2002543212A (ja)	2002-12-17
DK1175428T3 (da)	2003-08-11
NO20015347D0 (no)	2001-11-01
EE200100571A (et)	2003-02-17
EA200101169A1 (ru)	2002-04-25
HUP0201140A2 (en)	2002-08-28
HK1050010A1 (zh)	2003-06-06
CZ20013821A3 (cs)	2002-03-13

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Legal Events

Date	Code	Title	Description
2005-02-15	GB1A	Change in the ownership or in the address of the owner
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20090502