EE05559B1 - IL6R/IL6 kim„„ri kasutamine ravimi valmistamiseks, mis on ette n„htud neuroloogiliste haiguste ja h„irete ravimiseks ja/v?i v„ltimiseks - Google Patents

IL6R/IL6 kim„„ri kasutamine ravimi valmistamiseks, mis on ette n„htud neuroloogiliste haiguste ja h„irete ravimiseks ja/v?i v„ltimiseks

Info

Publication number
EE05559B1
EE05559B1 EEP200100689A EEP200100689A EE05559B1 EE 05559 B1 EE05559 B1 EE 05559B1 EE P200100689 A EEP200100689 A EE P200100689A EE P200100689 A EEP200100689 A EE P200100689A EE 05559 B1 EE05559 B1 EE 05559B1
Authority
EE
Estonia
Prior art keywords
disorders
prevention
treatment
il6r
kim
Prior art date
Application number
EEP200100689A
Other languages
English (en)
Estonian (et)
Inventor
Revel Michel
Chebath Judith
Pizzi Marina
Spano Pierfranco
Boschert Ursula
Original Assignee
Yeda Research And Development Co. Ltd.
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research And Development Co. Ltd., Applied Research Systems Ars Holding N.V. filed Critical Yeda Research And Development Co. Ltd.
Publication of EE200100689A publication Critical patent/EE200100689A/xx
Publication of EE05559B1 publication Critical patent/EE05559B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EEP200100689A 1999-06-21 2000-06-21 IL6R/IL6 kim„„ri kasutamine ravimi valmistamiseks, mis on ette n„htud neuroloogiliste haiguste ja h„irete ravimiseks ja/v?i v„ltimiseks EE05559B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13058699A IL130586A0 (en) 1999-06-21 1999-06-21 IL6RIL6 chimera for the treatment of demyelinating diseases
PCT/IL2000/000363 WO2000078331A2 (en) 1999-06-21 2000-06-21 Il6ril6 chimera for the treatment of neurodegenerative diseases

Publications (2)

Publication Number Publication Date
EE200100689A EE200100689A (et) 2003-02-17
EE05559B1 true EE05559B1 (et) 2012-08-15

Family

ID=11072949

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100689A EE05559B1 (et) 1999-06-21 2000-06-21 IL6R/IL6 kim„„ri kasutamine ravimi valmistamiseks, mis on ette n„htud neuroloogiliste haiguste ja h„irete ravimiseks ja/v?i v„ltimiseks

Country Status (20)

Country Link
US (1) US7201896B1 (de)
EP (1) EP1185293B1 (de)
JP (1) JP4846148B2 (de)
KR (1) KR100678290B1 (de)
CN (1) CN1164328C (de)
AT (1) ATE306280T1 (de)
AU (1) AU778662B2 (de)
BR (1) BR0011363A (de)
CA (1) CA2374997C (de)
DE (1) DE60023139T2 (de)
DK (1) DK1185293T3 (de)
EA (1) EA004626B1 (de)
EE (1) EE05559B1 (de)
ES (1) ES2250140T3 (de)
IL (2) IL130586A0 (de)
MX (1) MXPA02000116A (de)
NO (1) NO329028B1 (de)
UA (1) UA76695C2 (de)
WO (1) WO2000078331A2 (de)
ZA (1) ZA200109488B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2262680T3 (es) * 2000-09-14 2006-12-01 Ares Trading S.A. Uso de una quimera il-6r/il-6 en la enfermedad de huntington.
DE10107737A1 (de) * 2001-02-16 2002-09-05 S Rose John Christian Albrecht Verwendung eines Konjugats aus IL-6 und einem IL-6 Rezeptor zur Tumortherapie
JP4594588B2 (ja) * 2001-04-10 2010-12-08 ザ ボード オブ トラスティーズ オブ ザ リランド スタンフォード ジュニア ユニヴァーシティ 抗体特異的プロファイルの治療的および診断的使用方法
IL147412A0 (en) * 2001-12-31 2002-08-14 Yeda Res & Dev The use of il6r/il6 chimera in nerve cell regeneration
US8617887B2 (en) 2003-06-12 2013-12-31 Yeda Research And Development Co. Ltd Method of generating oligodendrocytes from neurosphere cells
US20070071727A1 (en) * 2003-11-14 2007-03-29 Olsson Mats J Melanocytes in therapy of neurodegenerative diseases
IL161672A0 (en) 2004-04-29 2004-09-27 Yeda Res & Dev Compositions and methods for therapy of chemotherapy-induced neuropathy
IL163856A0 (en) * 2004-09-01 2005-12-18 Applied Research Systems Use of IL-6 in vascular complications
CN108778121A (zh) * 2016-02-12 2018-11-09 Als治疗发展研究所 基于动力学数据评估als病情进展
US11207354B2 (en) 2016-09-23 2021-12-28 Osaka University Schwann cell differentiation promoting agent and a peripheral nerve regeneration promoting agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL122818A0 (en) * 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
JPH1148413A (ja) 1997-08-06 1999-02-23 Dainippon Printing Co Ltd ホルムアルデヒド捕捉壁紙およびその製造方法
JP4859153B2 (ja) * 1999-02-25 2012-01-25 東ソー株式会社 新規神経系細胞分化促進剤

Also Published As

Publication number Publication date
ZA200109488B (en) 2002-11-18
CA2374997A1 (en) 2000-12-28
KR20020013901A (ko) 2002-02-21
EP1185293B1 (de) 2005-10-12
EP1185293A2 (de) 2002-03-13
CN1364088A (zh) 2002-08-14
WO2000078331A2 (en) 2000-12-28
CN1164328C (zh) 2004-09-01
BR0011363A (pt) 2002-02-26
NO329028B1 (no) 2010-08-02
NO20015673L (no) 2001-12-17
NO20015673D0 (no) 2001-11-20
KR100678290B1 (ko) 2007-02-05
WO2000078331A3 (en) 2001-07-05
US7201896B1 (en) 2007-04-10
DE60023139D1 (de) 2006-02-23
AU778662B2 (en) 2004-12-16
AU5423100A (en) 2001-01-09
HK1047549A1 (en) 2003-02-28
EE200100689A (et) 2003-02-17
IL130586A0 (en) 2000-06-01
UA76695C2 (uk) 2006-09-15
ATE306280T1 (de) 2005-10-15
MXPA02000116A (es) 2003-07-21
DK1185293T3 (da) 2005-12-27
JP4846148B2 (ja) 2011-12-28
IL147188A (en) 2015-09-24
DE60023139T2 (de) 2006-05-04
CA2374997C (en) 2010-04-13
ES2250140T3 (es) 2006-04-16
EA200200063A1 (ru) 2002-06-27
JP2003502382A (ja) 2003-01-21
EA004626B1 (ru) 2004-06-24

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Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
HC1A Change of owner name
MM4A Lapsed by not paying the annual fees

Effective date: 20160621