EE200000538A - TNF/NGF retseptoriperekonna retseptorite ja muudevalkude talitluse modulaatorid, nende valmistamine ja kasutamine ning farmatseutiline kompositsioon - Google Patents

TNF/NGF retseptoriperekonna retseptorite ja muudevalkude talitluse modulaatorid, nende valmistamine ja kasutamine ning farmatseutiline kompositsioon

Info

Publication number
EE200000538A
EE200000538A EEP200000538A EEP200000538A EE200000538A EE 200000538 A EE200000538 A EE 200000538A EE P200000538 A EEP200000538 A EE P200000538A EE P200000538 A EEP200000538 A EE P200000538A EE 200000538 A EE200000538 A EE 200000538A
Authority
EE
Estonia
Prior art keywords
tnf
modulators
functioning
proteins
preparation
Prior art date
Application number
EEP200000538A
Other languages
English (en)
Estonian (et)
Inventor
Wallach David
Kovalenko Andrei
S. Horwitz Marshall
Li Yongan
Original Assignee
Yeda Research And Development Co. Ltd.
Albert Einstein College Of Medicine Of Yeshiva University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12375898A external-priority patent/IL123758A0/xx
Application filed by Yeda Research And Development Co. Ltd., Albert Einstein College Of Medicine Of Yeshiva University filed Critical Yeda Research And Development Co. Ltd.
Priority to EEP200900055A priority Critical patent/EE200900055A/xx
Publication of EE200000538A publication Critical patent/EE200000538A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200000538A 1998-03-19 1999-03-18 TNF/NGF retseptoriperekonna retseptorite ja muudevalkude talitluse modulaatorid, nende valmistamine ja kasutamine ning farmatseutiline kompositsioon EE200000538A (et)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EEP200900055A EE200900055A (et) 1998-03-19 1999-03-18 TNF/NFG retseptoriperekonna retseptorite ja muude valkude talitluse modulaatorid, nende valmistamine ja kasutamine ning farmatseutiline kompositsioon

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL12375898A IL123758A0 (en) 1998-03-19 1998-03-19 Modulators of the function of receptors of the TNF/NGF receptor family and other proteins
IL12602498A IL126024A0 (en) 1998-03-19 1998-09-01 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
PCT/IL1999/000158 WO1999047672A1 (en) 1998-03-19 1999-03-18 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
CA002323637A CA2323637A1 (en) 1998-03-19 1999-03-18 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins

Publications (1)

Publication Number Publication Date
EE200000538A true EE200000538A (et) 2002-04-15

Family

ID=39598416

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000538A EE200000538A (et) 1998-03-19 1999-03-18 TNF/NGF retseptoriperekonna retseptorite ja muudevalkude talitluse modulaatorid, nende valmistamine ja kasutamine ning farmatseutiline kompositsioon

Country Status (23)

Country Link
US (1) US6734174B1 (pl)
EP (1) EP1062336B1 (pl)
JP (1) JP4351389B2 (pl)
KR (1) KR100748293B1 (pl)
CN (1) CN1232641C (pl)
AT (1) ATE318310T1 (pl)
AU (1) AU760900B2 (pl)
BG (2) BG64990B1 (pl)
BR (1) BR9909659A (pl)
CA (2) CA2323637A1 (pl)
DE (1) DE69929958T2 (pl)
DK (1) DK1062336T3 (pl)
EA (1) EA004062B1 (pl)
EE (1) EE200000538A (pl)
ES (1) ES2258838T3 (pl)
HU (1) HUP0101612A3 (pl)
IL (1) IL126024A0 (pl)
NO (1) NO327854B1 (pl)
NZ (2) NZ506776A (pl)
PL (1) PL200763B1 (pl)
PT (1) PT1062336E (pl)
SK (1) SK285804B6 (pl)
WO (1) WO1999047672A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7189832B1 (en) * 1998-08-20 2007-03-13 The Regents Of The University Of California Gamma subunit of cytokine responsive IκB-alpha kinase complex and methods of using same
US7745579B1 (en) 1998-09-01 2010-06-29 David Wallach Inhibitor of NF-KB activation
TR201809678T4 (tr) 2001-06-26 2018-07-23 Amgen Fremont Inc Opgl ye karşi antikorlar.
US7521534B1 (en) * 2003-03-03 2009-04-21 The University Board Of Regents Of Texas System IKK gamma gene products and methods for making and using same
BRPI0414714A (pt) * 2003-09-24 2006-11-21 Pasteur Institut polinucleotìdeo purificado, vetor, célula hospedeira, construto de fusão de polipeptìdeo, métodos de inibir a rota de sinalização de nf-capab, de interromper a oligomerização de nemo, e, de identificar polipeptìdeos que modulam a oligomerização de nemo, e, uso de uma quantidade eficaz de uma composição
KR101278690B1 (ko) * 2009-10-19 2013-06-24 한올바이오파마주식회사 변형된 인간 종양 괴사 인자 수용체-1 폴리펩티드 또는 그의 절편 및 그의 제조방법
CN102399819B (zh) * 2011-08-24 2013-06-19 西北农林科技大学 一种质粒型腺病毒载体pAd-NRIP1及其构建方法
DE102011115480A1 (de) * 2011-10-06 2013-04-11 Biostep Gmbh Substrat und Vorrichtung zur Chemilumineszenzdetektion
WO2016094846A1 (en) 2014-12-11 2016-06-16 President And Fellows Of Harvard College Inhibitors of cellular necrosis and related methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL73883A (en) * 1984-12-20 1990-12-23 Yeda Res & Dev Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha
IL94039A (en) * 1989-08-06 2006-09-05 Yeda Res & Dev Antibodies to tbp - 1 and their use
AU636608B2 (en) * 1989-05-18 1993-05-06 Yeda Research And Development Co. Ltd. Tumor necrosis factor binding protein II, it's purification and antibodies thereto
WO1996025941A1 (en) * 1995-02-22 1996-08-29 Yeda Research And Development Co. Ltd. Modulators of regulatory proteins
US5674734A (en) * 1995-05-18 1997-10-07 President And Fellows Of Harvard College Cell death protein
AU7457796A (en) 1995-10-23 1997-05-15 Tularik Inc. Rip: novel human protein involved in tumor necrosis factor signal transduction, and screening assays
AU3228197A (en) * 1996-05-29 1998-01-05 Genzyme Corporation Cell growth regulatory genes

Also Published As

Publication number Publication date
EP1062336A1 (en) 2000-12-27
DK1062336T3 (da) 2006-05-29
US6734174B1 (en) 2004-05-11
BG104769A (en) 2001-04-30
NO20004649D0 (no) 2000-09-18
JP4351389B2 (ja) 2009-10-28
JP2002506644A (ja) 2002-03-05
HUP0101612A2 (hu) 2004-01-28
KR20050107527A (ko) 2005-11-11
EP1062336B1 (en) 2006-02-22
BR9909659A (pt) 2000-11-21
CA2625284A1 (en) 1999-09-23
AU2954599A (en) 1999-10-11
NZ506776A (en) 2003-08-29
PT1062336E (pt) 2006-05-31
BG64990B1 (bg) 2006-11-30
AU760900B2 (en) 2003-05-22
WO1999047672A1 (en) 1999-09-23
SK13762000A3 (sk) 2001-03-12
IL126024A0 (en) 1999-05-09
NO20004649L (no) 2000-10-30
DE69929958D1 (de) 2006-04-27
ATE318310T1 (de) 2006-03-15
CN1295614A (zh) 2001-05-16
BG65684B1 (bg) 2009-06-30
KR100748293B1 (ko) 2007-08-09
DE69929958T2 (de) 2006-11-23
HUP0101612A3 (en) 2005-03-29
ES2258838T3 (es) 2006-09-01
CN1232641C (zh) 2005-12-21
EA004062B1 (ru) 2003-12-25
NO327854B1 (no) 2009-10-05
HK1034995A1 (en) 2001-11-09
EA200000961A1 (ru) 2001-04-23
SK285804B6 (sk) 2007-08-02
PL343262A1 (en) 2001-07-30
NZ525566A (en) 2004-12-24
CA2323637A1 (en) 1999-09-23
BG109537A (en) 2007-11-30
PL200763B1 (pl) 2009-02-27

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