EE200000625A - Atsetüülkoliinkoostiste stabiliseerimise meetodidja koostised - Google Patents

Atsetüülkoliinkoostiste stabiliseerimise meetodidja koostised

Info

Publication number: EE200000625A
Authority: EE; Estonia
Prior art keywords: acetylcholine; compositions; buffered; stabilizing; product
Prior art date: 1998-04-29

Application number

EEP200000625A

Other languages

English (en)

Inventor

Tsao Fu-Pao

Edward Minno George

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-29

Filing date

1999-04-27

Publication date

2002-02-15

1999-04-27 Application filed by Novartis Ag filed Critical Novartis Ag

2002-02-15 Publication of EE200000625A publication Critical patent/EE200000625A/et

2005-08-15 Publication of EE04515B1 publication Critical patent/EE04515B1/et

Links

OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 title abstract 6
229960004373 acetylcholine Drugs 0.000 title abstract 6
238000000034 method Methods 0.000 title abstract 3
239000000203 mixture Substances 0.000 title 2
230000000087 stabilizing effect Effects 0.000 title 1
239000003085 diluting agent Substances 0.000 abstract 2
230000015556 catabolic process Effects 0.000 abstract 1
238000006731 degradation reaction Methods 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
229940127557 pharmaceutical product Drugs 0.000 abstract 1
239000000243 solution Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Ophthalmology & Optometry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Emergency Medicine (AREA)
Oil, Petroleum & Natural Gas (AREA)
Inorganic Chemistry (AREA)
Surgery (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Polymerisation Methods In General (AREA)
Compositions Of Macromolecular Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

EEP200000625A 1998-04-29 1999-04-27 Atsetlkoliinkoostiste stabiliseerimise meetodidja koostised EE04515B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US6955298A	1998-04-29	1998-04-29
PCT/EP1999/002846 WO1999055304A1 (en)	1998-04-29	1999-04-27	Methods and compositions for stabilizing acetylcholine compositions

Publications (2)

Publication Number	Publication Date
EE200000625A true EE200000625A (et)	2002-02-15
EE04515B1 EE04515B1 (et)	2005-08-15

Family

ID=22089751

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200000625A EE04515B1 (et)	1998-04-29	1999-04-27	Atsetlkoliinkoostiste stabiliseerimise meetodidja koostised

Country Status (24)

Country	Link
US (1)	US6261546B1 (et)
EP (1)	EP1073413B1 (et)
JP (1)	JP2002512945A (et)
KR (1)	KR100617429B1 (et)
CN (1)	CN1147289C (et)
AT (1)	ATE286380T1 (et)
AU (1)	AU745124B2 (et)
BR (1)	BR9910077A (et)
CA (1)	CA2327398C (et)
CZ (1)	CZ301969B6 (et)
DE (1)	DE69923063T2 (et)
EE (1)	EE04515B1 (et)
ES (1)	ES2235486T3 (et)
HU (1)	HU226104B1 (et)
ID (1)	ID26032A (et)
IL (1)	IL138775A0 (et)
NO (1)	NO20005372D0 (et)
NZ (1)	NZ507074A (et)
PL (1)	PL194092B1 (et)
PT (1)	PT1073413E (et)
RU (1)	RU2225199C2 (et)
SI (1)	SI1073413T1 (et)
UA (1)	UA72209C2 (et)
WO (1)	WO1999055304A1 (et)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2670436A1 (en)	2006-11-30	2008-06-05	Nihon Medi-Physics Co., Ltd.	Novel compound having affinity for amyloid
US20130029919A1 (en)	2011-07-26	2013-01-31	Allergan, Inc.	Two part formulation system for opthalmic delivery

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5009892A (en) *	1989-03-03	1991-04-23	Mckinzie James W	Rapid miosis with control of intraocular pressure
RU2056821C1 (ru) *	1993-02-26	1996-03-27	Межотраслевой научно-технический комплекс "Микрохирургия глаза"	Глазные капли "кератоник"
RU2100020C1 (ru) *	1993-06-23	1997-12-27	Лейрас Ой	Средство для местного лечения глазной гипертензии и глаукомы и способ его получения
US5565188A (en)	1995-02-24	1996-10-15	Nanosystems L.L.C.	Polyalkylene block copolymers as surface modifiers for nanoparticles
US5612027A (en)	1995-04-18	1997-03-18	Galin; Miles A.	Controlled release of miotic and mydriatic drugs in the anterior chamber

1999
- 1999-04-27 WO PCT/EP1999/002846 patent/WO1999055304A1/en not_active Ceased
- 1999-04-27 AT AT99923472T patent/ATE286380T1/de not_active IP Right Cessation
- 1999-04-27 ES ES99923472T patent/ES2235486T3/es not_active Expired - Lifetime
- 1999-04-27 ID IDW20002105A patent/ID26032A/id unknown
- 1999-04-27 PT PT99923472T patent/PT1073413E/pt unknown
- 1999-04-27 HU HU0100613A patent/HU226104B1/hu not_active IP Right Cessation
- 1999-04-27 IL IL13877599A patent/IL138775A0/xx not_active IP Right Cessation
- 1999-04-27 RU RU2000129158/15A patent/RU2225199C2/ru not_active IP Right Cessation
- 1999-04-27 KR KR1020007012014A patent/KR100617429B1/ko not_active Expired - Fee Related
- 1999-04-27 EE EEP200000625A patent/EE04515B1/et not_active IP Right Cessation
- 1999-04-27 DE DE69923063T patent/DE69923063T2/de not_active Expired - Lifetime
- 1999-04-27 PL PL99343174A patent/PL194092B1/pl not_active IP Right Cessation
- 1999-04-27 EP EP99923472A patent/EP1073413B1/en not_active Expired - Lifetime
- 1999-04-27 CA CA002327398A patent/CA2327398C/en not_active Expired - Fee Related
- 1999-04-27 CZ CZ20003961A patent/CZ301969B6/cs not_active IP Right Cessation
- 1999-04-27 JP JP2000545504A patent/JP2002512945A/ja active Pending
- 1999-04-27 UA UA2000106080A patent/UA72209C2/uk unknown
- 1999-04-27 NZ NZ507074A patent/NZ507074A/xx unknown
- 1999-04-27 BR BR9910077-0A patent/BR9910077A/pt not_active IP Right Cessation
- 1999-04-27 SI SI9930762T patent/SI1073413T1/xx unknown
- 1999-04-27 AU AU40340/99A patent/AU745124B2/en not_active Ceased
- 1999-04-27 CN CNB998055069A patent/CN1147289C/zh not_active Expired - Fee Related
- 1999-04-29 US US09/301,895 patent/US6261546B1/en not_active Expired - Fee Related
2000
- 2000-10-25 NO NO20005372A patent/NO20005372D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2327398C (en)	2008-12-30
ID26032A (id)	2000-11-16
EE04515B1 (et)	2005-08-15
NZ507074A (en)	2004-02-27
CZ20003961A3 (cs)	2001-01-17
NO20005372L (no)	2000-10-25
CA2327398A1 (en)	1999-11-04
WO1999055304A1 (en)	1999-11-04
BR9910077A (pt)	2000-12-26
KR100617429B1 (ko)	2006-08-30
HK1034204A1 (en)	2001-10-19
EP1073413B1 (en)	2005-01-05
NO20005372D0 (no)	2000-10-25
AU4034099A (en)	1999-11-16
PL194092B1 (pl)	2007-04-30
RU2225199C2 (ru)	2004-03-10
EP1073413A1 (en)	2001-02-07
ATE286380T1 (de)	2005-01-15
AU745124B2 (en)	2002-03-14
HUP0100613A2 (hu)	2001-08-28
PL343174A1 (en)	2001-07-30
UA72209C2 (en)	2005-02-15
JP2002512945A (ja)	2002-05-08
IL138775A0 (en)	2001-10-31
HUP0100613A3 (en)	2001-12-28
DE69923063D1 (de)	2005-02-10
CN1147289C (zh)	2004-04-28
CN1298295A (zh)	2001-06-06
PT1073413E (pt)	2005-04-29
DE69923063T2 (de)	2005-12-22
US6261546B1 (en)	2001-07-17
SI1073413T1 (et)	2005-08-31
KR20010043121A (ko)	2001-05-25
ES2235486T3 (es)	2005-07-01
HU226104B1 (en)	2008-04-28
CZ301969B6 (cs)	2010-08-18

Legal Events

Date	Code	Title	Description
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2011-12-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20110427

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