EE200200231A - Antihüpertensiivseid di- ja tripeptiide produtseeriv Lactobacillus helveticus - Google Patents

Antihüpertensiivseid di- ja tripeptiide produtseeriv Lactobacillus helveticus

Info

Publication number
EE200200231A
EE200200231A EEP200200231A EEP200200231A EE200200231A EE 200200231 A EE200200231 A EE 200200231A EE P200200231 A EEP200200231 A EE P200200231A EE P200200231 A EEP200200231 A EE P200200231A EE 200200231 A EE200200231 A EE 200200231A
Authority
EE
Estonia
Prior art keywords
tripeptides
lactobacillus helveticus
producing antihypertensive
antihypertensive
producing
Prior art date
Application number
EEP200200231A
Other languages
English (en)
Inventor
M�yr�-M�kinen Annika
Suomalainen Tarja
Original Assignee
Valio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valio Ltd filed Critical Valio Ltd
Publication of EE200200231A publication Critical patent/EE200200231A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1427—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by dialysis, reverse osmosis or hyperfiltration, e.g. for concentrating or desalting
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A23J3/344—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins of casein
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/66—Proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/147—Helveticus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Water Supply & Treatment (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
EEP200200231A 1999-11-01 2000-10-30 Antihüpertensiivseid di- ja tripeptiide produtseeriv Lactobacillus helveticus EE200200231A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI992360A FI113741B (fi) 1999-11-01 1999-11-01 Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi
PCT/FI2000/000941 WO2001032836A1 (en) 1999-11-01 2000-10-30 Lactobacillus helvetius producing antihypertensive di- and tripeptides

Publications (1)

Publication Number Publication Date
EE200200231A true EE200200231A (et) 2003-06-16

Family

ID=8555541

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200200231A EE200200231A (et) 1999-11-01 2000-10-30 Antihüpertensiivseid di- ja tripeptiide produtseeriv Lactobacillus helveticus
EEP200200230A EE05461B1 (et) 1999-11-01 2000-10-30 Antihpertensiivseid tripeptiide sisaldava toote valmistamise meetod

Family Applications After (1)

Application Number Title Priority Date Filing Date
EEP200200230A EE05461B1 (et) 1999-11-01 2000-10-30 Antihpertensiivseid tripeptiide sisaldava toote valmistamise meetod

Country Status (23)

Country Link
US (2) US6972282B1 (et)
EP (2) EP1226267B1 (et)
JP (2) JP4172681B2 (et)
KR (2) KR100718709B1 (et)
CN (2) CN1164761C (et)
AT (2) ATE266735T1 (et)
AU (2) AU769432B2 (et)
CA (2) CA2387738C (et)
CZ (2) CZ294146B6 (et)
DE (2) DE60010742T2 (et)
DK (2) DK1226267T3 (et)
EE (2) EE200200231A (et)
ES (2) ES2220557T3 (et)
FI (1) FI113741B (et)
HR (2) HRP20020378B1 (et)
HU (2) HUP0203185A3 (et)
NO (2) NO20022062L (et)
NZ (2) NZ518493A (et)
PL (2) PL364790A1 (et)
PT (2) PT1226230E (et)
RU (2) RU2270855C2 (et)
WO (2) WO2001032905A1 (et)
ZA (2) ZA200203172B (et)

Families Citing this family (53)

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FI113741B (fi) * 1999-11-01 2004-06-15 Valio Oy Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi
FI112031B (fi) 2002-02-25 2003-10-31 Valio Oy Biologisesti aktiivisen tuotteen uusi käyttö
AU2003236689A1 (en) 2002-06-04 2003-12-19 Dsm Ip Assets B.V. Protein hydrolysate rich in tripeptides
EP1529114A1 (en) 2002-08-09 2005-05-11 Chr. Hansen A/S Process for preparing peptides with anti-hypertensive properties
CN1735347A (zh) * 2003-01-06 2006-02-15 荷兰联合利华有限公司 含有三肽vpp和/或ipp的发酵乳制品
TWI344371B (en) * 2003-03-18 2011-07-01 Suntory Holdings Ltd Angiotensin-converting enzyme inhibitory peptides
US7718171B2 (en) 2003-04-07 2010-05-18 Chr. Hansen A/S Reducing heart rate in mammals using milk derived fermentation products produced using Lactobacillus helveticus
CN1784145A (zh) 2003-05-05 2006-06-07 荷兰联合利华有限公司 包含三肽ipp和/或vpp的水解酪蛋白产物
WO2005096847A1 (en) * 2004-03-19 2005-10-20 Campina Nederland Holding B.V. Method of preparing a food ingredient and food product having angiotensin-i-converting enzyme inhibiting properties and products thus obtained
EP1736164A4 (en) 2004-03-31 2009-06-24 Calpis Co Ltd AGENT TO PREVENT OR REMOVE HEPATOPATHY AND FUNCTIONAL FEED TO PREVENT OR DELETE HEPATOPATHY
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DE602006004956D1 (de) * 2006-02-20 2009-03-12 Gervais Danone Sa Neue Stämme von Lactobacillus helveticus
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RU2457852C2 (ru) * 2006-05-15 2012-08-10 Валио Лтд Новое применение терапевтически эффективных пептидов
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US10842813B2 (en) 2007-02-26 2020-11-24 Heartbeet Ltd Compositions of nitrates and methods of use thereof
US11759477B2 (en) 2007-02-26 2023-09-19 Heartbeet Ltd. Compositions of nitrates and methods of use thereof
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JP2011524744A (ja) * 2008-06-12 2011-09-08 ネステク ソシエテ アノニム 降圧ペプチドを産生するためのラクトバチルス・ヘルベティカス株
DE102008032828A1 (de) 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
FI122531B (fi) * 2009-09-30 2012-03-15 Valio Oy Juusto ja menetelmä sen valmistamiseksi
CN102786579B (zh) * 2012-07-17 2014-07-09 上海交通大学 抗高血压活性肽vip
CN102786580A (zh) * 2012-07-17 2012-11-21 上海交通大学 抗高血压活性肽ivp
RU2580052C1 (ru) * 2014-12-24 2016-04-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" Штамм lactobacillus helveticus вкпм в-11176, полученный на доступных питательных средах
RU2577112C1 (ru) * 2014-12-25 2016-03-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" Штамм lactobacillus helveticus вкпм в-11175, полученный на доступных питательных средах
EP3788881B1 (en) 2016-12-02 2022-07-06 Fairlife, LLC Non-browning lactose-free milk powder and methods of making same
RU2685912C1 (ru) * 2018-03-14 2019-04-23 Федеральное государственное автономное научное учреждение "Научно-исследовательский институт хлебопекарной промышленности" Штамм бактерий lactobacillus amylolyticus, используемый для приготовления термофильной заквашенной заварки
RU2728171C2 (ru) * 2018-11-08 2020-07-28 Общество с ограниченной ответственностью "Инновационные биотехнологии" (ООО "Инбиотех") Штамм бактерий Lactobacillus helveticus T-5068, используемый в качестве закваски прямого внесения для приготовления кисломолочных продуктов
CN109517763B (zh) * 2018-12-27 2022-03-22 内蒙古农业大学 瑞士乳杆菌h11及其应用
TWI713972B (zh) * 2019-01-14 2020-12-21 大江生醫股份有限公司 改善呼吸道健康之益生菌株及其組合物與用途
WO2021195718A1 (en) * 2020-04-02 2021-10-07 Ahtesh Fatah Bashir Milk fermentation process
CN112029784A (zh) * 2020-09-16 2020-12-04 内蒙古农业大学 一个与蛋白水解能力相关的基因及基于该基因的高蛋白水解能力瑞士乳杆菌的筛选方法
KR102684805B1 (ko) 2023-12-20 2024-07-12 푸른하늘환경주식회사 우수 유출수의 정화 처리 장치
KR102687298B1 (ko) 2023-12-20 2024-07-22 푸른하늘환경주식회사 비점오염물질 저감 및 우수 정화 장치
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GB9720633D0 (en) * 1997-09-29 1997-11-26 Univ Bristol BHV-2 vector
FI104783B (fi) 1998-02-12 2000-04-14 Valio Oy Herasuolajauhe, menetelmä sen valmistamiseksi ja sen käyttö
FI113741B (fi) * 1999-11-01 2004-06-15 Valio Oy Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi
US6514941B1 (en) * 1999-12-10 2003-02-04 Campina Melkunie B.V. Method of preparing a casein hydrolysate enriched in anti-hypertensive peptides

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