EE200200275A - Immunosupressantidena kasutatavad 2,4-diaminopürimidiiniühendid - Google Patents

Immunosupressantidena kasutatavad 2,4-diaminopürimidiiniühendid

Info

Publication number: EE200200275A
Authority: EE; Estonia
Prior art keywords: immunosuppressants; compounds used; diaminopyrimidine compounds; diaminopyrimidine; compounds
Prior art date: 1999-11-30

Application number

EEP200200275A

Other languages

English (en)

Estonian (et)

Inventor

Andrew Blumenkopf Todd

Elliott Mueller Eileen

Jan Roskamp Eric

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-30

Filing date

2000-11-09

Publication date

2003-10-15

2000-11-09 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2003-10-15 Publication of EE200200275A publication Critical patent/EE200200275A/xx

Links

229960003444 immunosuppressant agent Drugs 0.000 title 1
239000003018 immunosuppressive agent Substances 0.000 title 1
YAAWASYJIRZXSZ-UHFFFAOYSA-N pyrimidine-2,4-diamine Chemical class NC1=CC=NC(N)=N1 YAAWASYJIRZXSZ-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Hematology (AREA)
Neurology (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EEP200200275A 1999-11-30 2000-11-09 Immunosupressantidena kasutatavad 2,4-diaminopürimidiiniühendid EE200200275A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US16822499P	1999-11-30	1999-11-30
PCT/IB2000/001628 WO2001040215A1 (en)	1999-11-30	2000-11-09	2,4-diaminopyrimidine compounds usful as immunosuppressants

Publications (1)

Publication Number	Publication Date
EE200200275A true EE200200275A (et)	2003-10-15

Family

ID=22610621

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200200275A EE200200275A (et)	1999-11-30	2000-11-09	Immunosupressantidena kasutatavad 2,4-diaminopürimidiiniühendid

Country Status (33)

Country	Link
EP (1)	EP1242403B1 (is)
JP (1)	JP3955468B2 (is)
KR (1)	KR20020059826A (is)
CN (1)	CN1402720A (is)
AP (1)	AP2002002530A0 (is)
AT (1)	ATE315036T1 (is)
AU (1)	AU1047601A (is)
BG (1)	BG106695A (is)
BR (1)	BR0015995A (is)
CA (1)	CA2392971C (is)
CO (1)	CO5261519A1 (is)
CZ (1)	CZ20021703A3 (is)
DE (1)	DE60025385T2 (is)
EA (1)	EA200200411A1 (is)
EE (1)	EE200200275A (is)
ES (1)	ES2253266T3 (is)
GT (1)	GT200000200A (is)
HN (1)	HN2000000264A (is)
HU (1)	HUP0203300A3 (is)
IL (1)	IL149103A0 (is)
IS (1)	IS6339A (is)
MA (1)	MA26846A1 (is)
MX (1)	MXPA02005350A (is)
NO (1)	NO20022557D0 (is)
OA (1)	OA12097A (is)
PA (1)	PA8506801A1 (is)
PE (1)	PE20010900A1 (is)
PL (1)	PL355946A1 (is)
SV (1)	SV2002000231A (is)
TN (1)	TNSN00232A1 (is)
TR (1)	TR200201431T2 (is)
UY (1)	UY26455A1 (is)
WO (1)	WO2001040215A1 (is)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1257546A1 (en) *	2000-02-17	2002-11-20	Amgen Inc.	Kinase inhibitors
IL154016A0 (en) *	2000-08-31	2003-07-31	Pfizer Prod Inc	Pyrazole derivatives and their use as protein kinase inhibitors
US6660731B2 (en)	2000-09-15	2003-12-09	Vertex Pharmaceuticals Incorporated	Pyrazole compounds useful as protein kinase inhibitors
EP1317450B1 (en)	2000-09-15	2006-11-22	Vertex Pharmaceuticals Incorporated	Pyrazole compounds useful as protein kinase inhibitors
US7473691B2 (en)	2000-09-15	2009-01-06	Vertex Pharmaceuticals Incorporated	Pyrazole compounds useful as protein kinase inhibitors
NZ526472A (en)	2000-12-21	2004-04-30	Vertex Pharma	Pyrazole compounds useful as protein kinase inhibitors
WO2003030909A1 (en) *	2001-09-25	2003-04-17	Bayer Pharmaceuticals Corporation	2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer
MY141867A (en)	2002-06-20	2010-07-16	Vertex Pharma	Substituted pyrimidines useful as protein kinase inhibitors
DK1532145T3 (da)	2002-08-02	2007-01-15	Vertex Pharma	Pyrazolpræparater der er anvendelige som inhibitorer af GSK-3
DE10237423A1 (de) *	2002-08-16	2004-02-19	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung von LCK-Inhibitoren für die Behandlung von immunologischen Erkrankungen
US20040204458A1 (en)	2002-08-16	2004-10-14	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Use of Lck inhibitors for treatment of immunologic diseases
BRPI0506839A (pt) *	2004-01-16	2007-06-12	Novartis Ag	composições e métodos para induzir a cardiomiogênese
US20060142348A1 (en) *	2004-10-12	2006-06-29	Decode Chemistry, Inc.	Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease
US20060161001A1 (en) *	2004-12-20	2006-07-20	Amgen Inc.	Substituted heterocyclic compounds and methods of use
PE20060777A1 (es)	2004-12-24	2006-10-06	Boehringer Ingelheim Int	Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
EP1954277B1 (en)	2005-11-03	2017-01-18	Vertex Pharmaceuticals Incorporated	Aminopyrimidines useful as kinase inhibitors
TW200804389A (en)	2006-02-14	2008-01-16	Vertex Pharma	Dihydrodiazepines useful as inhibitors of protein kinases
MX2008011661A (es) *	2006-03-16	2008-09-22	Novartis Ag	Compuestos organicos heterociclicos para el tratamiento de melanoma en particular.
US9096546B2 (en)	2007-05-10	2015-08-04	Albany Molecular Research, Inc.	Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
BRPI0818338A2 (pt) *	2007-10-16	2015-04-22	Daiichi Sankyo Co Ltd	Composto de pirimidil indolina
SG179206A1 (en)	2009-09-25	2012-04-27	Vertex Pharma	Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
CA2773827A1 (en)	2009-09-25	2011-03-31	Vertex Pharmaceuticals Incorporated	Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
TWI513694B (zh) *	2010-05-11	2015-12-21	Amgen Inc	抑制間變性淋巴瘤激酶的嘧啶化合物
KR101708761B1 (ko) *	2012-04-13	2017-02-21	주식회사 머쉬메드	퓨린 유도체 또는 그의 염을 포함하는 아토피성 피부염의 예방 또는 치료용 조성물
EP3055301B1 (en) *	2013-10-07	2019-11-20	Kadmon Corporation, LLC	(2-(5-isoindolin-2-yl)pyrimidin-4-yl)-amine derivatives as rho kinase inhibitors for treating autoimmune diseases
CN110582489B (zh) *	2017-06-30	2023-10-27	北京泰德制药股份有限公司	Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
WO2019000682A1 (zh) *	2017-06-30	2019-01-03	北京泰德制药股份有限公司	Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
US10323023B2 (en)	2017-06-30	2019-06-18	Beijing Tide Pharmaceutical Co., Ltd.	Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9523675D0 (en) *	1995-11-20	1996-01-24	Celltech Therapeutics Ltd	Chemical compounds
EP0837063A1 (en) *	1996-10-17	1998-04-22	Pfizer Inc.	4-Aminoquinazoline derivatives
GB9905075D0 (en) *	1999-03-06	1999-04-28	Zeneca Ltd	Chemical compounds

2000
- 2000-11-09 TR TR2002/01431T patent/TR200201431T2/xx unknown
- 2000-11-09 CN CN00816506A patent/CN1402720A/zh active Pending
- 2000-11-09 JP JP2001541899A patent/JP3955468B2/ja not_active Expired - Fee Related
- 2000-11-09 BR BR0015995-6A patent/BR0015995A/pt not_active Application Discontinuation
- 2000-11-09 WO PCT/IB2000/001628 patent/WO2001040215A1/en not_active Ceased
- 2000-11-09 KR KR1020027006941A patent/KR20020059826A/ko not_active Ceased
- 2000-11-09 CZ CZ20021703A patent/CZ20021703A3/cs unknown
- 2000-11-09 MX MXPA02005350A patent/MXPA02005350A/es active IP Right Grant
- 2000-11-09 EE EEP200200275A patent/EE200200275A/xx unknown
- 2000-11-09 ES ES00971650T patent/ES2253266T3/es not_active Expired - Lifetime
- 2000-11-09 OA OA1200200156A patent/OA12097A/en unknown
- 2000-11-09 IL IL14910300A patent/IL149103A0/xx unknown
- 2000-11-09 PL PL00355946A patent/PL355946A1/xx not_active Application Discontinuation
- 2000-11-09 AT AT00971650T patent/ATE315036T1/de not_active IP Right Cessation
- 2000-11-09 CA CA002392971A patent/CA2392971C/en not_active Expired - Fee Related
- 2000-11-09 EP EP00971650A patent/EP1242403B1/en not_active Expired - Lifetime
- 2000-11-09 DE DE60025385T patent/DE60025385T2/de not_active Expired - Lifetime
- 2000-11-09 AP APAP/P/2002/002530A patent/AP2002002530A0/en unknown
- 2000-11-09 AU AU10476/01A patent/AU1047601A/en not_active Abandoned
- 2000-11-09 HU HU0203300A patent/HUP0203300A3/hu unknown
- 2000-11-09 EA EA200200411A patent/EA200200411A1/ru unknown
- 2000-11-22 PA PA20008506801A patent/PA8506801A1/es unknown
- 2000-11-23 HN HN2000000264A patent/HN2000000264A/es unknown
- 2000-11-28 UY UY26455A patent/UY26455A1/es not_active Application Discontinuation
- 2000-11-28 PE PE2000001268A patent/PE20010900A1/es not_active Application Discontinuation
- 2000-11-29 GT GT200000200A patent/GT200000200A/es unknown
- 2000-11-29 SV SV2000000231A patent/SV2002000231A/es unknown
- 2000-11-29 TN TNTNSN00232A patent/TNSN00232A1/fr unknown
- 2000-11-30 CO CO00091745A patent/CO5261519A1/es unknown
2002
- 2002-04-12 IS IS6339A patent/IS6339A/is unknown
- 2002-05-13 BG BG106695A patent/BG106695A/bg unknown
- 2002-05-28 MA MA26655A patent/MA26846A1/fr unknown
- 2002-05-29 NO NO20022557A patent/NO20022557D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE60025385T2 (de)	2006-08-24
IS6339A (is)	2002-04-12
TNSN00232A1 (fr)	2005-11-10
AU1047601A (en)	2001-06-12
EA200200411A1 (ru)	2002-10-31
AP2002002530A0 (en)	2002-06-30
GT200000200A (es)	2002-05-23
SV2002000231A (es)	2002-07-16
OA12097A (en)	2006-05-04
ATE315036T1 (de)	2006-02-15
CN1402720A (zh)	2003-03-12
JP3955468B2 (ja)	2007-08-08
UY26455A1 (es)	2001-07-31
NO20022557L (no)	2002-05-29
CO5261519A1 (es)	2003-03-31
BR0015995A (pt)	2002-08-06
ES2253266T3 (es)	2006-06-01
PL355946A1 (en)	2004-05-31
TR200201431T2 (tr)	2002-09-23
CA2392971C (en)	2008-10-07
KR20020059826A (ko)	2002-07-13
HN2000000264A (es)	2001-05-21
PE20010900A1 (es)	2001-09-08
EP1242403A1 (en)	2002-09-25
NO20022557D0 (no)	2002-05-29
DE60025385D1 (de)	2006-03-30
IL149103A0 (en)	2002-11-10
HUP0203300A3 (en)	2003-10-28
CA2392971A1 (en)	2001-06-07
WO2001040215A1 (en)	2001-06-07
BG106695A (bg)	2002-12-29
HUP0203300A2 (hu)	2003-02-28
CZ20021703A3 (cs)	2003-06-18
MXPA02005350A (es)	2002-12-11
MA26846A1 (fr)	2004-12-20
JP2003515602A (ja)	2003-05-07
EP1242403B1 (en)	2006-01-04
PA8506801A1 (es)	2002-04-25

Publication	Publication Date	Title
EE200200275A (et)	2003-10-15	Immunosupressantidena kasutatavad 2,4-diaminopürimidiiniühendid
PT1225874E (pt)	2006-06-30	Composicoes antivirais.
ITTO20000976A0 (it)	2000-10-18	Composizioni acaricide.
AP2002002529A0 (en)	2002-06-30	2,4-Diaminopyrimidine compounds useful as immunosupressants
DE60019577D1 (de)	2005-05-25	4, 5, 6, 7-tetrahydroindazolderivate als antitumormittel
ID27595A (id)	2001-04-12	SENYAWA-SENYAWA PIROLO (2,3-d) PIRIMIDINA
TR200000520A3 (tr)	2001-06-21	4-Fenil-piridin türevleri.
DK1175408T3 (da)	2005-04-11	Pyrimidinonforbindelser
ID28483A (id)	2001-05-31	2-(3,5-bis-trifluorometil-fenil)-metil-n-(6-morfolin-4-il-4-0-tolil-piridin-3-il)-isobutiramida
DE50107988D1 (de)	2005-12-15	Substituierte 1,2,3,4-tetrahydrochinolin-2-carbonsäurederivate
MXPA01011760A (es)	2003-09-04	Compuestos novedosos de difeniletileno.
DE60025958D1 (de)	2006-04-20	14,15-beta-methylen substituierte androgene
ITBO990359A0 (it)	1999-06-30	Elettromandrino .
DE60029755D1 (de)	2006-09-14	Congawandschutz.
ITBO990358A0 (it)	1999-06-30	Elettromandrino .
NL1011488A1 (nl)	2000-09-14	Hoofdtelefoon-microfoon-combinatie.
ATE470655T1 (de)	2010-06-15	Substituierte 1,5-diaminopentan-3-ol-verbindungen
ES1042496Y (es)	2000-02-01	"pilona sumible".
ES1044838Y (es)	2000-11-16	Friegasuelos.
ES1042877Y (es)	2000-03-01	Lama bi-cama.
DE60017150D1 (de)	2005-02-03	1,4,5,6 -tetrahydropyrimidine-derivative als vitronectin-hemmer
ITRM20000199A0 (it)	2000-04-14	Formulazione.
ITMI990856A1 (it)	2000-10-24	Composizione funghicida.
ITCS990004V0 (it)	1999-08-09	"termocamin0 c.c.m."
ITRM990553A0 (it)	1999-09-03	Electroprophylaxis (elettroprofilassi).