EE200200428A - Uudne tiotroopiumi sisaldav inhalatsioonipulber - Google Patents

Uudne tiotroopiumi sisaldav inhalatsioonipulber

Info

Publication number: EE200200428A
Authority: EE; Estonia
Prior art keywords: innovative; powder containing; inhalation powder; containing tiotropium; tiotropium
Prior art date: 2000-10-12

Application number

EEP200200428A

Other languages

English (en)

Inventor

Bechtold-Peters Karoline

Walz Michael

Boeck Georg

D�rr Rolf

Original Assignee

Boehringer Ingelheim Pharma Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-12

Filing date

2001-09-28

Publication date

2003-02-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE200200428(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-09-28 Application filed by Boehringer Ingelheim Pharma Kg filed Critical Boehringer Ingelheim Pharma Kg

2003-02-17 Publication of EE200200428A publication Critical patent/EE200200428A/et

2005-02-15 Publication of EE04414B1 publication Critical patent/EE04414B1/et

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Otolaryngology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EEP200200428A 2000-10-12 2001-09-28 Tiotroopiumi sisaldav inhalatsioonipulber, meetodselle valmistamiseks ja selle kasutamine ravimi valmistamiseks EE04414B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10050635		2000-10-12
PCT/EP2001/011227 WO2002030389A1 (de)	2000-10-12	2001-09-28	Neue tiotropium-haltige inhalationspulver

Publications (2)

Publication Number	Publication Date
EE200200428A true EE200200428A (et)	2003-02-17
EE04414B1 EE04414B1 (et)	2005-02-15

Family

ID=7659578

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200200428A EE04414B1 (et)	2000-10-12	2001-09-28	Tiotroopiumi sisaldav inhalatsioonipulber, meetodselle valmistamiseks ja selle kasutamine ravimi valmistamiseks

Country Status (48)

Country	Link
US (4)	US7070800B2 (et)
EP (2)	EP1292281B1 (et)
JP (1)	JP3870159B2 (et)
KR (1)	KR100488644B1 (et)
CN (1)	CN1210017C (et)
AP (1)	AP1712A (et)
AR (1)	AR031819A1 (et)
AT (1)	ATE275391T1 (et)
AU (1)	AU757008B2 (et)
BG (1)	BG65753B1 (et)
BR (1)	BR0107304A (et)
CA (1)	CA2395653C (et)
CR (1)	CR6937A (et)
CU (1)	CU23284B7 (et)
CZ (1)	CZ301465B6 (et)
DE (1)	DE50103551C5 (et)
DK (1)	DK1292281T3 (et)
DZ (1)	DZ3477A1 (et)
EA (1)	EA004034B1 (et)
EC (2)	ECSP024268A (et)
EE (1)	EE04414B1 (et)
EG (1)	EG24139A (et)
ES (1)	ES2227268T3 (et)
GE (1)	GEP20063865B (et)
HR (1)	HRP20020437B1 (et)
HU (1)	HU226982B1 (et)
IL (2)	IL149984A0 (et)
IS (1)	IS2360B (et)
MA (1)	MA25843A1 (et)
ME (2)	ME00245B (et)
MX (1)	MXPA02005666A (et)
MY (1)	MY123544A (et)
NO (1)	NO331956B1 (et)
NZ (1)	NZ519406A (et)
OA (1)	OA12522A (et)
PE (1)	PE20020577A1 (et)
PL (1)	PL200063B1 (et)
PT (1)	PT1292281E (et)
RS (1)	RS50197B (et)
SA (1)	SA01220460B1 (et)
SI (1)	SI1292281T1 (et)
SK (1)	SK285389B6 (et)
TR (1)	TR200402367T4 (et)
TW (1)	TWI285553B (et)
UA (1)	UA72014C2 (et)
UY (1)	UY26959A1 (et)
WO (1)	WO2002030389A1 (et)
ZA (1)	ZA200204378B (et)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK285389B6 (sk)	2000-10-12	2006-12-07	Boehringer Ingelheim Pharma Kg	Inhalačný prášok s obsahom tiotrópia, kapsula s jeho obsahom a ich použitie
PT2283818T (pt)	2000-11-30	2017-10-09	Vectura Ltd	Método de preparação de partículas para utilização numa composição farmacêutica
PT1337239E (pt)	2000-11-30	2010-01-26	Vectura Ltd	Partículas servindo à preparação de uma composição farmacêutica
US20030055026A1 (en) *	2001-04-17	2003-03-20	Dey L.P.	Formoterol/steroid bronchodilating compositions and methods of use thereof
US20030070679A1 (en) *	2001-06-01	2003-04-17	Boehringer Ingelheim Pharma Kg	Capsules containing inhalable tiotropium
DE10128779A1 (de) *	2001-06-13	2003-01-02	Boehringer Ingelheim Pharma	Verfahren zur Reinigung von Hartgelatinekapseln
US20030008001A1 (en) *	2001-06-13	2003-01-09	Boehringer Ingelheim Pharma Kg	Process for cleaning hard gelatine capsules
DE10141376A1 (de) *	2001-08-23	2003-03-13	Boehringer Ingelheim Pharma	Verfahren zur Herstellung von Inhalationspulvern
DE10141377A1 (de)	2001-08-23	2003-03-13	Boehringer Ingelheim Pharma	Aufstreuverfahren zur Herstellung von Pulverformulierungen
US7309707B2 (en) *	2002-03-20	2007-12-18	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament
DE10212264A1 (de)	2002-03-20	2003-10-02	Boehringer Ingelheim Pharma	Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
US7244415B2 (en) *	2002-03-28	2007-07-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations of an anhydrate
MXPA04009583A (es) *	2002-04-04	2005-01-11	Boehringer Ingelheim Pharma	Nuevas formulaciones en polvo adecuadas para inhalacion.
US20030235538A1 (en)	2002-04-09	2003-12-25	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Method for the administration of an anticholinergic by inhalation
CN101700247A (zh) *	2002-06-12	2010-05-05	埃匹吉尼斯医药有限公司	利用脱氢表雄酮甾体及抗毒蕈碱药物治疗呼吸道疾病及肺病的组合物、制剂和试剂盒
GB0219511D0 (en) *	2002-08-21	2002-10-02	Norton Healthcare Ltd	Method of preparing dry powder inhalation compositions
JP2006516531A (ja) *	2002-08-21	2006-07-06	ノートン　ヘルスケアー　リミテッド	吸入組成物
AU2003269989B8 (en) *	2002-08-21	2009-11-12	Norton Healthcare Ltd.	Inhalation composition
GB0219513D0 (en)	2002-08-21	2002-10-02	Norton Healthcare Ltd	Inhalation compositions including coarse carrier
US7763280B2 (en)	2002-11-28	2010-07-27	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Tiotropium containing powder formulation for inhalation
DE10255387A1 (de) *	2002-11-28	2004-06-09	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Tiotropium-haltige Pulverformulierung für die Inhalation
US20050058606A1 (en) *	2002-12-16	2005-03-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Tiotropium containing HFC solution formulations
US20040152720A1 (en) *	2002-12-20	2004-08-05	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Powdered medicaments containing a tiotropium salt and salmeterol xinafoate
DE10317461A1 (de)	2003-04-16	2004-10-28	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
US20040226556A1 (en)	2003-05-13	2004-11-18	Deem Mark E.	Apparatus for treating asthma using neurotoxin
JP2007517537A (ja)	2003-06-13	2007-07-05	アドバンストインハレーションリサーチ，インコーポレイテッド	吸入用低投薬量医薬粉末
TWI359675B (en) *	2003-07-10	2012-03-11	Dey L P	Bronchodilating β-agonist compositions
US20050038004A1 (en) *	2003-07-31	2005-02-17	Robinson Cynthia B.	Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
KR20060117334A (ko)	2003-11-03	2006-11-16	베링거 인겔하임 인터내셔날 게엠베하	티오트로피움 염의 제조방법, 티오트로피움 염 및 이를함유하는 약제학적 조성물
EP2083007B1 (de)	2003-11-03	2013-04-24	Boehringer Ingelheim International Gmbh	Tiotropiumsalze, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittelformulierungen
SE0303270L (sv) *	2003-12-03	2005-06-04	Microdrug Ag	Metod för administration av tiotropium
EP1691782A1 (en) *	2003-12-03	2006-08-23	Microdrug AG	Medical product containing tiotropium
BRPI0417097A (pt) *	2003-12-03	2007-03-13	Microdrug Ag	inalador de pó seco de dose previamente medida para medicamentos sensìveis à umidade
SE0303570L (sv) *	2003-12-03	2005-06-04	Microdrug Ag	Fukt-känslig medicinsk produkt
SE0303269L (sv) *	2003-12-03	2005-06-04	Microdrug Ag	Medicinsk produkt
DE102004048389A1 (de)	2004-10-01	2006-04-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
ES2613391T3 (es)	2005-02-10	2017-05-24	Glaxo Group Limited	Procedimientos de fabricación de lactosa que utilizan técnicas de preclasificación y formulaciones farmacéuticas formadas a partir de la misma
DK1881980T3 (da) *	2005-05-02	2012-10-01	Boehringer Ingelheim Int	Nye krystalline former af tiotropiumbromid
NZ564697A (en) *	2005-06-15	2010-04-30	Boehringer Ingelheim Int	Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof
TWI274641B (en) *	2005-08-30	2007-03-01	Rexon Ind Corp Ltd	Cutting machine
US9108962B2 (en)	2005-12-19	2015-08-18	Sicor, Inc.	Forms of tiotropium bromide and processes for preparation thereof
RU2453547C2 (ru) *	2005-12-19	2012-06-20	Сикор Инк.	Новые формы тиотропия бромида и способы их получения
US20070167480A1 (en) *	2005-12-19	2007-07-19	Sicor Inc.	Pure and stable tiotropium bromide
RS52663B2 (sr) *	2005-12-19	2018-05-31	Sicor Inc	Nova kristalna forma tiotropijum bromida i proces njene pripreme
CA2620142A1 (en) *	2005-12-19	2007-07-05	Sicor Inc.	Pure and stable tiotropium bromide
US20080051582A1 (en) *	2006-07-10	2008-02-28	Sicor Inc.	Process for the preparation of tiotropium bromide
GB0716026D0 (en) *	2007-08-16	2007-09-26	Norton Healthcare Ltd	An inhalable medicament
CN103691530A (zh)	2007-07-27	2014-04-02	卡吉尔公司	多元醇的微粉化
US8483831B1 (en)	2008-02-15	2013-07-09	Holaira, Inc.	System and method for bronchial dilation
JP2011519699A (ja)	2008-05-09	2011-07-14	インノブアトイブエプルモナルイソルウトイオンス，インコーポレイティッド	気管支樹の治療のためのシステム、アセンブリ、及び方法
EP2172190A1 (en)	2008-10-02	2010-04-07	Laboratorios Liconsa, S.A.	Inhalable particles comprising tiotropium
SG174389A1 (en)	2009-03-17	2011-10-28	Daiichi Sankyo Co Ltd	Amide derivative
CA2779135C (en)	2009-10-27	2018-09-04	Innovative Pulmonary Solutions, Inc.	Delivery devices with coolable energy emitting assemblies
EP2842510B1 (en)	2009-11-11	2022-08-24	Nuvaira, Inc.	Device for treating tissue and controlling stenosis
US8911439B2 (en)	2009-11-11	2014-12-16	Holaira, Inc.	Non-invasive and minimally invasive denervation methods and systems for performing the same
US8834931B2 (en)	2009-12-25	2014-09-16	Mahmut Bilgic	Dry powder formulation containing tiotropium for inhalation
US9259376B2 (en)	2010-06-03	2016-02-16	Sima Patent Ve Lisanslama Hizmetleri Ltd. Sti.	Process for dry powder formulations
TR201007251A2 (tr) *	2010-09-01	2012-03-21	Bi̇lgi̇ç Mahmut	Kalsiyum kanal blokörü formülasyonu.
GB201200525D0 (en)	2011-12-19	2012-02-29	Teva Branded Pharmaceutical Prod R & D Inc	An inhalable medicament
US20150165038A1 (en) *	2012-02-10	2015-06-18	Arven llac Sanayi Ve Ticaret A.S.	Compositions comprising muscarinic receptor antagonist and sorbitol
JP6335798B2 (ja)	2012-02-28	2018-05-30	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規噴射剤含有チオトロピウム製剤
RU2522213C2 (ru) *	2012-06-07	2014-07-10	Шолекс Девелопмент Гмбх,	Фармацевтический ингаляционный препарат для лечения бронхиальной астмы и хронической обструктивной болезни легких, содержащих в качестве активного вещества микронизированный тиотропия бромид, и способ его получения
US20150165037A1 (en) *	2012-07-05	2015-06-18	Arven llac Sanayi Ve Ticaret A.S.	Inhalation compositions comprising corticosteroid and sorbitol
US20150150802A1 (en)	2012-07-05	2015-06-04	Arven Ilac Sanayi Ve Ticaret Anonim Sirketi	Dry powder inhaler compositions comprising long acting muscarinic antagonists
WO2014007772A2 (en) *	2012-07-05	2014-01-09	Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi	Inhalation compositions comprising glucose anhydrous
US10105316B2 (en)	2012-07-05	2018-10-23	Arven llac Sanayi Ve Ticaret A.S.	Inhalation compositions comprising muscarinic receptor antagonist
US20150224197A1 (en) *	2012-07-05	2015-08-13	Arven Ilac Sanayi Ve Ticaret A.S.	Inhalation compositions
US20150174064A1 (en) *	2012-07-05	2015-06-25	Arven IIac Sanayi Ve Ticaret A.S.	Compositions comprising muscarinic receptor antagonist and glucose anhydrous
EP2705838A1 (en) *	2012-09-06	2014-03-12	Xspray Microparticles Ab	Tiotropium preparations
US9398933B2 (en)	2012-12-27	2016-07-26	Holaira, Inc.	Methods for improving drug efficacy including a combination of drug administration and nerve modulation
WO2015065222A1 (ru) *	2013-10-28	2015-05-07	Шолекс Девелопмент Гмбх	Фармацевтический ингаляционный препарат для лечения бронхиальной астмы и хронической обструктивной болезни легких, содержащий в качестве активного вещества микронизированный тиотропия бромид, и способ его получения
EP2913332A1 (en)	2014-02-27	2015-09-02	Euticals S.P.A.	Crystalline form of tiotropium bromide with lactose
US10034866B2 (en)	2014-06-19	2018-07-31	Teva Branded Pharmaceutical Products R&D, Inc.	Inhalable medicament comprising tiotropium
DK3159277T3 (da)	2015-10-23	2019-09-02	Arven Ilac Sanayi Ve Ticaret As	Blister til inhalerbar formulering af tiotropiumbromid
KR101728116B1 (ko) *	2015-11-03	2017-04-18	한미약품 주식회사	티오트로피움 또는 이의 약학적으로 허용가능한 염을 함유하는 흡입용 건조분말 조성물
SG11201804598RA (en)	2015-12-24	2018-07-30	Philip Morris Products Sa	Flavoured nicotine powder
EA201992234A1 (ru)	2017-03-23	2020-02-05	Сингапур Хелт Сервисиз Пте Лтд	Средство для профилактики миопии, лечения миопии и/или предотвращения прогрессирования миопии, включающее тиотропий в качестве активного ингредиента
EP4108230A1 (en)	2021-06-24	2022-12-28	Laboratoires SMB	New dry powder composition of tiotropium for inhalation
GR1010358B (el) *	2021-09-14	2022-12-16	Elpen Ανωνυμος Εταιρεια Φαρμακευτικη Βιομηχανια,	Σταθερο φαρμακευτικο σκευασμα που περιεχει βρωμιουχο τιοτροπιο, για χορηγηση απο το αναπνευστικο

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3860618A (en) *	1967-08-08	1975-01-14	Philip Saxton Hartley	Chromone
US3957965A (en) *	1967-08-08	1976-05-18	Fisons Limited	Sodium chromoglycate inhalation medicament
GB1242211A (en) *	1967-08-08	1971-08-11	Fisons Pharmaceuticals Ltd	Pharmaceutical composition
DE2540633A1 (de) *	1975-09-12	1977-04-28	Boehringer Sohn Ingelheim	Neue quartaere n-beta-substituierte benzilsaeure-n-alkyl-nortropinester und verfahren zu deren herstellung
DE3211185A1 (de) *	1982-03-26	1983-09-29	Boehringer Ingelheim KG, 6507 Ingelheim	Neue quartaere 6,11-dihydro-dibenzo-(b,e)-thiepin-11-n-alkyl- norscopinether und verfahren zu deren herstellung
DE3215493A1 (de) *	1982-04-26	1983-11-03	Boehringer Ingelheim KG, 6507 Ingelheim	Neue zwischenprodukte, verfahren zu ihrer herstellung und ihre verwendung
JPS60172442A (ja)	1984-02-20	1985-09-05	Fanuc Ltd	ならい加工およびνｃ加工による機械加工装置
DE3931041C2 (de)	1989-09-16	2000-04-06	Boehringer Ingelheim Kg	Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US5610163A (en) *	1989-09-16	1997-03-11	Boehringer Ingelheim Gmbh	Esters of thienyl carboxylic acids and amino alcohols and their quaternization products
DE4108393A1 (de) *	1991-03-15	1992-09-17	Boehringer Ingelheim Kg	Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln
ATE170745T1 (de) *	1991-04-08	1998-09-15	Nippon Shinyaku Co Ltd	Kapsel mit langzeitwirkung fuer die adhäsion im gastrointestinaltrakt
DE4140689B4 (de) *	1991-12-10	2007-11-22	Boehringer Ingelheim Kg	Inhalationspulver und Verfahren zu ihrer Herstellung
US5770738A (en) *	1992-03-05	1998-06-23	Boehringer Ingelheim Kg	Esters of bi- and tricyclic amino alcohols, their preparation and their use in pharmaceutical compositions
DE4318455A1 (de) *	1993-06-03	1994-12-08	Boehringer Ingelheim Kg	Kapselhalterung
US5819730A (en)	1993-06-09	1998-10-13	Glaxo Wellcome Australia Ltd.	Device for administering pharmaceutical substances
ES2152281T3 (es) *	1993-09-28	2001-02-01	Scherer Gmbh R P	Fabricacion de capsulas de gelatina blanda.
GB9322014D0 (en) *	1993-10-26	1993-12-15	Co Ordinated Drug Dev	Improvements in and relating to carrier particles for use in dry powder inhalers
GB9404945D0 (en) *	1994-03-15	1994-04-27	Glaxo Group Ltd	Pharmaceutical composition
DE4425255A1 (de)	1994-07-16	1996-01-18	Asta Medica Ag	Formulierung zur inhalativen Applikation
DE19515625C2 (de) *	1995-04-28	1998-02-19	Boehringer Ingelheim Kg	Verfahren zur Herstellung von enantiomerenreinen Tropasäureestern
FR2757173A1 (fr) *	1996-12-17	1998-06-19	Warner Lambert Co	Compositions polymeres d'origine non-animale pour la formation de films
US6228394B1 (en) *	1997-10-14	2001-05-08	Boehringer Ingelheim Pharmaceuticals, Inc.	Supercritical fluid extraction of mould lubricant from hard shell capsules
US6235725B1 (en) *	1998-10-30	2001-05-22	Baker Norton Pharmaceuticals, Inc.	Methods and compositions for the prevention of tolerance to medications
EP1131059B1 (de) *	1998-11-13	2003-03-05	Jago Research Ag	Trockenpulver zur inhalation
GB9902689D0 (en) *	1999-02-08	1999-03-31	Novartis Ag	Organic compounds
US20040002548A1 (en) *	1999-05-12	2004-01-01	Boehringer Ingelheim Pharma Kg	Medicament compositions containing anticholinergically-effective compounds and betamimetics
JP3931486B2 (ja) *	1999-06-24	2007-06-13	住友化学株式会社	ポジ型レジスト組成物
US6908928B2 (en) *	2000-10-12	2005-06-21	Bi Pharma Kg.	Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions
UA75375C2 (en) *	2000-10-12	2006-04-17	Boehringer Ingelheim Pharma	Method for producing powdery preparations for inhaling
SK285389B6 (sk)	2000-10-12	2006-12-07	Boehringer Ingelheim Pharma Kg	Inhalačný prášok s obsahom tiotrópia, kapsula s jeho obsahom a ich použitie
DE10064816A1 (de) *	2000-12-22	2002-06-27	Boehringer Ingelheim Pharma	Verfahren zur Herstellung eines Anticholinergikums
US6506900B1 (en) *	2001-01-31	2003-01-14	Boehringer Ingelheim Pharma Ag	Process for preparing a scopine ester intermediate
US20030070679A1 (en) *	2001-06-01	2003-04-17	Boehringer Ingelheim Pharma Kg	Capsules containing inhalable tiotropium
DE10126924A1 (de)	2001-06-01	2002-12-05	Boehringer Ingelheim Pharma	Inhalationskapseln
US6482429B1 (en) *	2001-06-20	2002-11-19	Boehringer Ingelheim Pharmaceuticals, Inc.	Stable powder inhalation dosage formulation
DE10141376A1 (de) *	2001-08-23	2003-03-13	Boehringer Ingelheim Pharma	Verfahren zur Herstellung von Inhalationspulvern
DE10141377A1 (de) *	2001-08-23	2003-03-13	Boehringer Ingelheim Pharma	Aufstreuverfahren zur Herstellung von Pulverformulierungen
US7309707B2 (en) *	2002-03-20	2007-12-18	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament
MXPA04009583A (es)	2002-04-04	2005-01-11	Boehringer Ingelheim Pharma	Nuevas formulaciones en polvo adecuadas para inhalacion.
US20030235538A1 (en) *	2002-04-09	2003-12-25	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Method for the administration of an anticholinergic by inhalation
UA80123C2 (en)	2002-04-09	2007-08-27	Boehringer Ingelheim Pharma	Inhalation kit comprising inhalable powder of tiotropium
US7763280B2 (en) *	2002-11-28	2010-07-27	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Tiotropium containing powder formulation for inhalation

2001
- 2001-09-28 SK SK706-2002A patent/SK285389B6/sk not_active IP Right Cessation
- 2001-09-28 UA UA2002064932A patent/UA72014C2/uk unknown
- 2001-09-28 AU AU89935/01A patent/AU757008B2/en not_active Expired
- 2001-09-28 OA OA1200300108A patent/OA12522A/fr unknown
- 2001-09-28 IL IL14998401A patent/IL149984A0/xx active IP Right Grant
- 2001-09-28 ES ES01969789T patent/ES2227268T3/es not_active Expired - Lifetime
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- 2001-09-28 MX MXPA02005666A patent/MXPA02005666A/es active IP Right Grant
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- 2001-09-28 AP APAP/P/2003/002774A patent/AP1712A/en active
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- 2001-09-28 EA EA200200551A patent/EA004034B1/ru not_active IP Right Cessation
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- 2001-09-28 NZ NZ519406A patent/NZ519406A/en not_active IP Right Cessation
- 2001-09-28 EP EP04006349A patent/EP1430887A1/de not_active Withdrawn
- 2001-09-28 CZ CZ20021785A patent/CZ301465B6/cs not_active IP Right Cessation
- 2001-09-28 WO PCT/EP2001/011227 patent/WO2002030389A1/de not_active Ceased
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- 2001-09-28 AT AT01969789T patent/ATE275391T1/de active
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2002
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2003
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Also Published As

Publication number	Publication date
YU36302A (sh)	2002-09-19
PT1292281E (pt)	2004-11-30
KR20020063912A (ko)	2002-08-05
AP1712A (en)	2007-01-24
HK1051812A1 (en)	2003-08-22
HUP0203885A2 (hu)	2003-03-28
UY26959A1 (es)	2002-06-20
AU757008B2 (en)	2003-01-30
CZ20021785A3 (cs)	2002-09-11
NO331956B1 (no)	2012-05-14
DE50103551C5 (de)	2014-08-21
BG106730A (bg)	2003-03-31
PL200063B1 (pl)	2008-12-31
SK285389B6 (sk)	2006-12-07
DK1292281T3 (da)	2004-10-11
DE50103551D1 (de)	2004-10-14
UA72014C2 (en)	2005-01-17
MY123544A (en)	2006-05-31
AR031819A1 (es)	2003-10-08
JP2004510805A (ja)	2004-04-08
OA12522A (en)	2006-05-30
US20040228806A1 (en)	2004-11-18
HRP20020437B1 (en)	2005-10-31
NZ519406A (en)	2003-07-25
TR200402367T4 (tr)	2004-12-21
TWI285553B (en)	2007-08-21
ATE275391T1 (de)	2004-09-15
CN1392795A (zh)	2003-01-22
CN1210017C (zh)	2005-07-13
EP1292281B1 (de)	2004-09-08
HUP0203885A3 (en)	2005-01-28
BR0107304A (pt)	2002-08-13
DZ3477A1 (et)	2002-04-18
IL149984A (en)	2007-06-03
ES2227268T3 (es)	2005-04-01
SK7062002A3 (en)	2002-10-08
EE04414B1 (et)	2005-02-15
ME00245B (me)	2011-02-10
IL149984A0 (en)	2002-12-01
SA01220460B1 (ar)	2006-10-31
US7070800B2 (en)	2006-07-04
CA2395653C (en)	2006-05-09
IS6771A (is)	2003-04-08
NO20022414L (no)	2002-05-30
GEP20063865B (en)	2006-07-10
BG65753B1 (bg)	2009-10-30
MA25843A1 (fr)	2003-07-01
CR6937A (es)	2003-11-28
PL356840A1 (en)	2004-07-12
EA200200551A1 (ru)	2002-12-26
CZ301465B6 (cs)	2010-03-10
WO2002030389A1 (de)	2002-04-18
ECSP034546A (es)	2003-06-25
KR100488644B1 (ko)	2005-05-11
HRP20020437A2 (en)	2004-08-31
US20020110529A1 (en)	2002-08-15
EP1292281A1 (de)	2003-03-19
US20080292563A1 (en)	2008-11-27
MEP40108A (en)	2011-02-10
IS2360B (is)	2008-05-15
US20060039868A1 (en)	2006-02-23
HU226982B1 (en)	2010-04-28
NO20022414D0 (no)	2002-05-22
ECSP024268A (es)	2002-08-01
EP1430887A1 (de)	2004-06-23
SI1292281T1 (sl)	2004-12-31
CA2395653A1 (en)	2002-04-18
AP2003002774A0 (en)	2003-03-31
CU23284B7 (es)	2008-06-30
JP3870159B2 (ja)	2007-01-17
EG24139A (en)	2008-08-06
ZA200204378B (en)	2003-05-19
MXPA02005666A (es)	2002-11-29
PE20020577A1 (es)	2002-08-08
EA004034B1 (ru)	2003-12-25
AU8993501A (en)	2002-04-22
RS50197B (sr)	2009-05-06

Legal Events

Date	Code	Title	Description
2003-06-16	HC1A	Change of owner name
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231

Publication	Publication Date	Title
EE200200428A (et)	2003-02-17	Uudne tiotroopiumi sisaldav inhalatsioonipulber
EG24478A (en)	2009-08-03	New inhalable powder containing tiotropium
ATE460955T1 (de)	2010-04-15	Trockenpulver-inhalator
DE60130156D1 (de)	2007-10-04	Inhalator
EP1307256A4 (en)	2006-04-12	dry powder inhaler
FI990913L (fi)	2000-10-24	Jauheinhalaattori yhdistelmälääkkeelle
ATE285752T1 (de)	2005-01-15	Inhalationskapseln
FI990914L (fi)	2000-10-24	Jauheinhalaattori yhdistelmälääkkeelle
AU145610S (en)	2001-10-18	Inhaler
PL364773A1 (pl)	2004-12-13	Inhalator dozujący ksynafonian salmeterolu
IL157580A0 (en)	2004-03-28	Inhalation drug combination
DE60221611D1 (de)	2007-09-20	Trockenpulverinhalator
DE60142021D1 (de)	2010-06-17	Behältermundstück
AU145556S (en)	2001-10-10	Inhaler
GB0101239D0 (en)	2001-02-28	Medicinal aerosols
DE60123539D1 (de)	2006-11-16	Puderquaste
NO20053090D0 (no)	2005-06-23	Pulverformulering for innhalering inneholdende tiotropium.
DK1173244T3 (da)	2005-02-28	Pulverinhalator til kombineret medikament
GB0027836D0 (en)	2000-12-27	Disposable powder inhaler
DK1267974T3 (da)	2005-08-01	Inhalationsapparat
AU145135S (en)	2001-09-07	Inhaler
GB0025751D0 (en)	2000-12-06	Inhaler
GB0029979D0 (en)	2001-01-24	Inhaler
GB0031560D0 (en)	2001-02-07	Inhaler
SI1267971T1 (sl)	2007-04-30	Inhalator