EE200200506A - 5-alküülpürido[2,3-d]pürimidiinid kui türosiinkinaasi inhibiitorid - Google Patents

5-alküülpürido[2,3-d]pürimidiinid kui türosiinkinaasi inhibiitorid

Info

Publication number
EE200200506A
EE200200506A EEP200200506A EEP200200506A EE200200506A EE 200200506 A EE200200506 A EE 200200506A EE P200200506 A EEP200200506 A EE P200200506A EE P200200506 A EEP200200506 A EE P200200506A EE 200200506 A EE200200506 A EE 200200506A
Authority
EE
Estonia
Prior art keywords
alkylpyrido
pyrimidines
tyrosine kinase
kinase inhibitors
inhibitors
Prior art date
Application number
EEP200200506A
Other languages
English (en)
Estonian (et)
Inventor
Laurence Toogood Peter
John Booth Richard
Myra Dobrusin Ellen
Norman Vanderwel Scott
Original Assignee
Warner-Lambert Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company filed Critical Warner-Lambert Company
Publication of EE200200506A publication Critical patent/EE200200506A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200200506A 2000-03-06 2001-01-29 5-alküülpürido[2,3-d]pürimidiinid kui türosiinkinaasi inhibiitorid EE200200506A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18712400P 2000-03-06 2000-03-06
PCT/US2001/002657 WO2001070741A1 (fr) 2000-03-06 2001-01-29 Inhibiteurs de tyrosine kinase a base de 5-alkylpyrido[2,3-d]pyrimidines

Publications (1)

Publication Number Publication Date
EE200200506A true EE200200506A (et) 2004-02-16

Family

ID=22687699

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200506A EE200200506A (et) 2000-03-06 2001-01-29 5-alküülpürido[2,3-d]pürimidiinid kui türosiinkinaasi inhibiitorid

Country Status (37)

Country Link
EP (1) EP1268476A1 (fr)
JP (1) JP2003528101A (fr)
KR (1) KR20020075805A (fr)
CN (1) CN1422268A (fr)
AP (1) AP2002002643A0 (fr)
AR (1) AR034119A1 (fr)
AU (1) AU2001233028A1 (fr)
BG (1) BG107161A (fr)
BR (1) BR0109056A (fr)
CA (1) CA2401368A1 (fr)
CO (1) CO5280200A1 (fr)
CR (1) CR6736A (fr)
CZ (1) CZ20022929A3 (fr)
DZ (1) DZ3308A1 (fr)
EA (1) EA200200802A1 (fr)
EE (1) EE200200506A (fr)
GT (1) GT200100037A (fr)
HN (1) HN2001000040A (fr)
HR (1) HRP20020798A2 (fr)
HU (1) HUP0300136A2 (fr)
IL (1) IL151480A0 (fr)
IS (1) IS6524A (fr)
MA (1) MA26881A1 (fr)
MX (1) MXPA02008535A (fr)
NO (1) NO20024235L (fr)
NZ (1) NZ520962A (fr)
OA (1) OA12227A (fr)
PA (1) PA8513201A1 (fr)
PE (1) PE20011177A1 (fr)
PL (1) PL358271A1 (fr)
PY (1) PY0104899A (fr)
SK (1) SK12472002A3 (fr)
SV (1) SV2001000338A (fr)
TN (1) TNSN01036A1 (fr)
WO (1) WO2001070741A1 (fr)
YU (1) YU66502A (fr)
ZA (1) ZA200207110B (fr)

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US7235551B2 (en) 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
ATE521353T1 (de) 2000-10-23 2011-09-15 Glaxosmithkline Llc Neues trisubstitutiertes 8h-pyridoä2,3- düpyrimidin-7-onderivat zur behandlung von durch csbp/p38kinase vermittelten krankheiten
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ES2251677T3 (es) * 2002-01-22 2006-05-01 Warner-Lambert Company Llc 2-(piridin-2-ilamino)-pirido(2,3-d)pirimidin-7-onas.
KR20040103972A (ko) 2002-04-19 2004-12-09 스미스클라인 비참 코포레이션 신규 화합물
US7585866B2 (en) 2002-07-31 2009-09-08 Critical Outcome Technologies, Inc. Protein tyrosine kinase inhibitors
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US6861422B2 (en) 2003-02-26 2005-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
ATE412650T1 (de) * 2003-07-11 2008-11-15 Warner Lambert Co Isethionat salz eines selektiven cdk4 inhibitors
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Also Published As

Publication number Publication date
SK12472002A3 (sk) 2003-04-01
PY0104899A (es) 2003-11-03
EA200200802A1 (ru) 2003-02-27
PE20011177A1 (es) 2001-11-23
MA26881A1 (fr) 2004-12-20
WO2001070741A1 (fr) 2001-09-27
CR6736A (es) 2004-03-10
SV2001000338A (es) 2001-11-30
NO20024235L (no) 2002-11-05
EP1268476A1 (fr) 2003-01-02
CO5280200A1 (es) 2003-05-30
NO20024235D0 (no) 2002-09-05
AU2001233028A1 (en) 2001-10-03
MXPA02008535A (es) 2002-12-13
YU66502A (sh) 2005-09-19
TNSN01036A1 (en) 2005-11-10
AP2002002643A0 (en) 2002-12-31
AR034119A1 (es) 2004-02-04
PL358271A1 (pl) 2004-08-09
HUP0300136A2 (en) 2003-05-28
PA8513201A1 (es) 2003-06-30
GT200100037A (es) 2002-03-04
HN2001000040A (es) 2001-09-06
DZ3308A1 (fr) 2001-09-27
CZ20022929A3 (cs) 2003-02-12
IS6524A (is) 2002-08-23
JP2003528101A (ja) 2003-09-24
NZ520962A (en) 2003-09-26
BG107161A (bg) 2003-06-30
OA12227A (en) 2004-03-18
HRP20020798A2 (en) 2004-02-29
CA2401368A1 (fr) 2001-09-27
BR0109056A (pt) 2003-06-03
KR20020075805A (ko) 2002-10-05
CN1422268A (zh) 2003-06-04
ZA200207110B (en) 2003-12-04
IL151480A0 (en) 2003-04-10

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