EE9900155A - 1H-pürido[3,4-b]indool-4-karboksamiidi derivaadid, nende valmistamismeetod ja kasutamine raviks - Google Patents

1H-pürido[3,4-b]indool-4-karboksamiidi derivaadid, nende valmistamismeetod ja kasutamine raviks

Info

Publication number
EE9900155A
EE9900155A EEP199900155A EE9900155A EE9900155A EE 9900155 A EE9900155 A EE 9900155A EE P199900155 A EEP199900155 A EE P199900155A EE 9900155 A EE9900155 A EE 9900155A EE 9900155 A EE9900155 A EE 9900155A
Authority
EE
Estonia
Prior art keywords
pyrido
indole
therapy
preparation
carboxamide derivatives
Prior art date
Application number
EEP199900155A
Other languages
English (en)
Other versions
EE03830B1 (et
Inventor
Evanno Yannick
Sevrin Mireille
Maloizel Christian
Legalloudec Odette
George Pascal
Original Assignee
Synthlabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthlabo filed Critical Synthlabo
Publication of EE9900155A publication Critical patent/EE9900155A/et
Publication of EE03830B1 publication Critical patent/EE03830B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
EEP199900155A 1996-10-08 1997-10-03 1H-pürido[3,4-b]indool-4-karboksamiidi derivaadid, nende valmistamismeetodid ja kasutamine raviks EE03830B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9612229A FR2754262B1 (fr) 1996-10-08 1996-10-08 Derives de 1h-pyrido[3,4-b]indole-4-carboxamide, leur preparation et leur application en therapeutique
PCT/FR1997/001750 WO1998015552A1 (fr) 1996-10-08 1997-10-03 DERIVES DE 1H-PYRIDO[3,4-b]INDOLE-4-CARBOXAMIDE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE

Publications (2)

Publication Number Publication Date
EE9900155A true EE9900155A (et) 1999-12-15
EE03830B1 EE03830B1 (et) 2002-08-15

Family

ID=9496449

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900155A EE03830B1 (et) 1996-10-08 1997-10-03 1H-pürido[3,4-b]indool-4-karboksamiidi derivaadid, nende valmistamismeetodid ja kasutamine raviks

Country Status (32)

Country Link
US (1) US6075021A (et)
EP (1) EP0934319B1 (et)
JP (1) JP4227197B2 (et)
KR (1) KR100488095B1 (et)
CN (1) CN1089765C (et)
AR (1) AR009112A1 (et)
AT (1) ATE218567T1 (et)
AU (1) AU721102B2 (et)
BG (1) BG63751B1 (et)
BR (1) BR9711879A (et)
CA (1) CA2266376A1 (et)
CO (1) CO4910141A1 (et)
CY (1) CY2291B1 (et)
CZ (1) CZ298906B6 (et)
DE (1) DE69713124T2 (et)
DK (1) DK0934319T3 (et)
EE (1) EE03830B1 (et)
ES (1) ES2178008T3 (et)
FR (1) FR2754262B1 (et)
HU (1) HUP9904623A3 (et)
IL (1) IL129018A0 (et)
NO (1) NO311938B1 (et)
NZ (1) NZ334708A (et)
PL (1) PL188244B1 (et)
PT (1) PT934319E (et)
RU (1) RU2180904C2 (et)
SK (1) SK282970B6 (et)
TR (1) TR199900712T2 (et)
TW (1) TW461889B (et)
UA (1) UA57037C2 (et)
WO (1) WO1998015552A1 (et)
ZA (1) ZA978970B (et)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2766823B1 (fr) 1997-07-30 1999-10-08 Synthelabo Derives de 4-oxo-3,5-dihydro-4h-pyridazino[4,5-b] indole-1-acetamide, leur preparation et leur application en therapeutique
FR2788696B1 (fr) * 1999-01-26 2004-03-05 Synthelabo Utilisation de derives de pyridazino [4,5-b] indole-1-acetamide pour la preparation de medicaments destines aux maladies du systeme nerveux central
FR2788776B1 (fr) * 1999-01-26 2001-02-23 Synthelabo Derives de 4-oxo-3, 5-dihydro-4h-pyridazino [4,5-b] indole-1 -carboxamide, leur preparation et leur application en therapeutique
FR2811990A1 (fr) * 2000-07-24 2002-01-25 Sanofi Synthelabo DERIVES DE 1-(4-OXO-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-b]INDOLE-1 -CARBONYL)PIPERAZINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2811897A1 (fr) * 2000-07-24 2002-01-25 Sanofi Synthelabo UTILISATION DE DERIVES DE PYRIDAZINO[4,5-b]INDOLE-1- ACETAMIDE POUR LA PREPARATION DE MEDICAMENTS DESTINES AU TRAITEMENT DES DYSFONCTIONNEMENTS DES RECEPTEURS DE TYPE PERIPHERIQUE AUX BENZODIAZEPINES
FR2833953B1 (fr) 2001-12-21 2004-12-03 Sanofi Synthelabo DERIVES DE 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO [4,5-b]INDOLE-1-CARBOXAMIDE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2838124B1 (fr) * 2002-04-03 2004-05-28 Sanofi Synthelabo Derives de 3-heteroaryl-3,5-dihydro-4-oxo-4h-pyridazino [4,5-b]indole-1-acetamide, leur preparation et leur application en therapeutique
PA8586801A1 (es) * 2002-10-31 2005-02-04 Pfizer Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso
BRPI0407052A (pt) * 2003-01-27 2006-01-17 Pfizer Inibidores da hiv-integrase, composições farmacêuticas, e métodos para sua utilização
WO2005103051A1 (en) * 2004-04-26 2005-11-03 Pfizer Inc. Inhibitors of the hiv integrase enzyme
MXPA06012449A (es) * 2004-04-26 2007-01-17 Pfizer Inhibidores de la enzima integrasa de vih.
US20070238727A1 (en) * 2004-05-17 2007-10-11 Tibotec Bvba 5-Substituted 1-Phenyl-1,5-Dihydro-Pyrido[3,2-B]Indol-2-Ones and Analogs as Anti-Virals
CA2606861C (en) * 2005-05-05 2012-08-07 Sanofi-Aventis U.S. Llc Stable nanoparticle formulations
BRPI0616657A2 (pt) * 2005-10-07 2011-06-28 Pfizer Prod Inc inibidores da enzima hiv integrase
UA95788C2 (en) 2005-12-15 2011-09-12 Ф. Хоффманн-Ля Рош Аг Fused pyrrole derivatives
CL2007001597A1 (es) * 2006-06-05 2008-05-16 Novartis Ag Xenon Pharmaceutic Compuestos derivados de 2-oxo-piridin-1(2h)-il-tiazol, imidazol o tiofen-carboxamida; composicion farmaceutica; y uso para el tratamiento de una enfermedad mediada por la estearoil-coa-desaturasa, tal como sindrome metabolico, hipertension y diabetes
CN1946120B (zh) * 2006-10-20 2010-05-12 华为技术有限公司 实现话单关联的方法及系统
KR100688448B1 (ko) * 2006-12-06 2007-03-02 (주)경진건축사사무소 건축물 내부 조적구조
EP4353262A4 (en) * 2021-06-10 2025-05-21 UIF (University Industry Foundation), Yonsei University NEW COMPOUND WITH INHIBITORY EFFECT AGAINST PENDRIN AND PHARMACEUTICAL USES THEREOF

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3322895A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)
US5206377A (en) * 1991-12-05 1993-04-27 Whitby Research, Inc. Compounds useful as antiproliferative agents
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament

Also Published As

Publication number Publication date
BR9711879A (pt) 1999-08-24
NZ334708A (en) 2000-10-27
SK282970B6 (sk) 2003-01-09
BG63751B1 (bg) 2002-11-29
DK0934319T3 (da) 2002-09-30
AU4559497A (en) 1998-05-05
PT934319E (pt) 2002-10-31
HUP9904623A2 (hu) 2000-06-28
ZA978970B (en) 1998-04-20
NO311938B1 (no) 2002-02-18
JP2001508403A (ja) 2001-06-26
FR2754262A1 (fr) 1998-04-10
UA57037C2 (uk) 2003-06-16
KR20000048992A (ko) 2000-07-25
EP0934319A1 (fr) 1999-08-11
KR100488095B1 (ko) 2005-05-09
CZ119399A3 (cs) 1999-07-14
EP0934319B1 (fr) 2002-06-05
DE69713124D1 (de) 2002-07-11
CY2291B1 (en) 2003-07-04
AU721102B2 (en) 2000-06-22
RU2180904C2 (ru) 2002-03-27
BG103301A (en) 2000-05-31
SK45199A3 (en) 2000-02-14
CZ298906B6 (cs) 2008-03-12
HUP9904623A3 (en) 2001-03-28
CO4910141A1 (es) 2000-04-24
TW461889B (en) 2001-11-01
CN1233248A (zh) 1999-10-27
CN1089765C (zh) 2002-08-28
US6075021A (en) 2000-06-13
HK1023338A1 (en) 2000-09-08
IL129018A0 (en) 2000-02-17
CA2266376A1 (en) 1998-04-16
EE03830B1 (et) 2002-08-15
PL332643A1 (en) 1999-09-27
ES2178008T3 (es) 2002-12-16
AR009112A1 (es) 2000-03-08
TR199900712T2 (xx) 1999-06-21
ATE218567T1 (de) 2002-06-15
DE69713124T2 (de) 2003-01-30
WO1998015552A1 (fr) 1998-04-16
JP4227197B2 (ja) 2009-02-18
NO991624L (no) 1999-06-07
FR2754262B1 (fr) 1998-10-30
NO991624D0 (no) 1999-04-06
PL188244B1 (pl) 2005-01-31

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