EE200000207A - 8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, nende valmistamine ja terapeutiline kasutamine - Google Patents

8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, nende valmistamine ja terapeutiline kasutamine

Info

Publication number: EE200000207A
Authority: EE; Estonia
Prior art keywords: azabicyclo; octane; preparation; therapeutic use; methanamine derivatives
Prior art date: 1997-10-09

Application number

EEP200000207A

Other languages

English (en)

Inventor

Marabout Benoit

Sevrin Mireille

George Pascal

Merly Jean-Pierre

de Peretti Dani�le

Roy Jocelyne

Machnik David

Original Assignee

Sanofi-Synthlabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-09

Filing date

1998-10-07

Publication date

2001-04-16

1997-10-09 Priority claimed from FR9712580A external-priority patent/FR2769628B1/fr

1997-10-09 Priority claimed from FR9712583A external-priority patent/FR2769629B1/fr

1998-10-07 Application filed by Sanofi-Synthlabo filed Critical Sanofi-Synthlabo

2001-04-16 Publication of EE200000207A publication Critical patent/EE200000207A/et

2004-08-16 Publication of EE04347B1 publication Critical patent/EE04347B1/et

Links

AGYGGNCSLGICML-UHFFFAOYSA-N 8-azabicyclo[3.2.1]octan-3-ylmethanamine Chemical class C1C(CN)CC2CCC1N2 AGYGGNCSLGICML-UHFFFAOYSA-N 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Emergency Medicine (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Child & Adolescent Psychology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Hematology (AREA)
Nutrition Science (AREA)
Obesity (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

EEP200000207A 1997-10-09 1998-10-07 8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, neid sisaldav ravim ja farmatseutiline kompositsioon EE04347B1 (et)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR9712580A FR2769628B1 (fr)	1997-10-09	1997-10-09	Derives de n-(2,3-dihydro-1h-inden-2-yl)-n-propyl-8- azabicyclo[3.2.1.]octane-3-methanamine, leur preparation et leur application en therapeutique
FR9712583A FR2769629B1 (fr)	1997-10-09	1997-10-09	Derives de 8-azabicyclo[3.2.1]octane-3-methanamine, leur preparation et leur application en therapeutique
PCT/FR1998/002137 WO1999019325A1 (fr)	1997-10-09	1998-10-07	Derives de 8-azabicyclo [3.2.1] octane-3-methanamine en tant que ligands des recepteurs de dopamine d2 et d3 et de serotonine 5ht1a et 5ht2

Publications (2)

Publication Number	Publication Date
EE200000207A true EE200000207A (et)	2001-04-16
EE04347B1 EE04347B1 (et)	2004-08-16

Family

ID=26233854

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200000207A EE04347B1 (et)	1997-10-09	1998-10-07	8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, neid sisaldav ravim ja farmatseutiline kompositsioon

Country Status (30)

Country	Link
US (1)	US6221879B1 (et)
EP (1)	EP1021442B1 (et)
JP (1)	JP4505135B2 (et)
KR (1)	KR20010015717A (et)
CN (1)	CN1140526C (et)
AR (1)	AR017300A1 (et)
AT (1)	ATE212631T1 (et)
AU (1)	AU746935B2 (et)
BG (1)	BG64859B1 (et)
BR (1)	BR9812752A (et)
CA (1)	CA2305468C (et)
CO (1)	CO5011097A1 (et)
CZ (1)	CZ290679B6 (et)
DE (1)	DE69803689T2 (et)
DK (1)	DK1021442T3 (et)
EE (1)	EE04347B1 (et)
ES (1)	ES2171306T3 (et)
HU (1)	HUP0102086A3 (et)
IL (2)	IL135520A0 (et)
NO (1)	NO325170B1 (et)
NZ (1)	NZ503829A (et)
PL (1)	PL186998B1 (et)
PT (1)	PT1021442E (et)
RU (1)	RU2203281C2 (et)
SI (1)	SI1021442T1 (et)
SK (1)	SK283080B6 (et)
TR (1)	TR200000942T2 (et)
TW (1)	TW444014B (et)
UA (1)	UA58476C2 (et)
WO (1)	WO1999019325A1 (et)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6689806B1 (en)	1999-03-24	2004-02-10	Sugen, Inc.	Indolinone compounds as kinase inhibitors
US6878733B1 (en)	1999-11-24	2005-04-12	Sugen, Inc.	Formulations for pharmaceutical agents ionizable as free acids or free bases
DE122008000002I1 (de)	2000-02-15	2008-04-17	Sugen Inc	Pyrrol substituierte indolin-2-on protein kinase inhibitoren
AR042586A1 (es)	2001-02-15	2005-06-29	Sugen Inc	3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
ATE520659T1 (de) *	2004-10-14	2011-09-15	Abbott Gmbh & Co Kg	Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete azabicycloheptylverbindungen
AU2006214233A1 (en)	2005-02-17	2006-08-24	Wyeth	Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
MY145633A (en) *	2006-03-01	2012-03-15	Theravance Inc	8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists
TWI475015B (zh)	2010-03-11	2015-03-01	Sumitomo Dainippon Pharma Co Ltd	Ｎ－醯基環狀胺衍生物或其醫藥上容許之鹽
EP3230256B1 (en) *	2014-12-09	2019-11-13	Ezekiel Golan	Alcoholic beverage substitutes
EP3230255B1 (en)	2014-12-09	2020-03-18	Ezekiel Golan	Binge behavior regulators
KR102128782B1 (ko)	2018-09-20	2020-07-01	한양대학교 에리카산학협력단	트로페인(Tropane) 알칼로이드 화합물 및 순차적 산화반응을 이용한 이의 제조방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL59004A0 (en)	1978-12-30	1980-03-31	Beecham Group Ltd	Substituted benzamides their preparation and pharmaceutical compositions containing them
JPS5592384A (en) *	1978-12-30	1980-07-12	Beecham Group Ltd	Compound having pharmacological activity
US4350691A (en) *	1979-12-20	1982-09-21	Beecham Group Limited	Certain azabicyclocarboxamides and compositions containing same
US4910302A (en) *	1988-12-19	1990-03-20	American Home Products Corporation	Psychotropic polycyclic imides
FR2659323B1 (fr) *	1990-03-07	1992-06-12	Synthelabo	Derives de 4-(aminomethyl) piperidine, leur preparation et leur application en therapeutique.
NZ241481A (en) *	1991-02-04	1994-06-27	Hoechst Roussel Pharma	Derivatives of 8-aza-bicyclo[3.2.1]octane and pharmaceutical compositions thereof
FR2681320B1 (fr)	1991-09-12	1994-01-14	Synthelabo	Derives de n-(4,7dimethoxyindan-2-yl)-1-(phenylcarbonyl)-n-propyl-piperidine-4-methanamine, leur preparation et leur application en therapeutique.
FR2681325B1 (fr) *	1991-09-16	1993-12-17	Fabre Medicament Pierre	Derives de l'aminomethyl-4 piperidine, leur preparation et leur application en therapeutique.
DE4135474A1 (de)	1991-10-28	1993-04-29	Bayer Ag	2-aminomethyl-chromane
FR2702211B1 (fr)	1993-03-04	1995-06-02	Pf Medicament	Nouveaux dérivés de la phénoxy-2 éthylamine, leur préparation et leur application en thérapeutique.

1998
- 1998-07-10 UA UA2000041930A patent/UA58476C2/uk unknown
- 1998-10-06 AR ARP980104978A patent/AR017300A1/es active IP Right Grant
- 1998-10-07 SK SK504-2000A patent/SK283080B6/sk not_active IP Right Cessation
- 1998-10-07 ES ES98947615T patent/ES2171306T3/es not_active Expired - Lifetime
- 1998-10-07 CZ CZ20001278A patent/CZ290679B6/cs not_active IP Right Cessation
- 1998-10-07 JP JP2000515897A patent/JP4505135B2/ja not_active Expired - Fee Related
- 1998-10-07 HU HU0102086A patent/HUP0102086A3/hu unknown
- 1998-10-07 TR TR2000/00942T patent/TR200000942T2/xx unknown
- 1998-10-07 DK DK98947615T patent/DK1021442T3/da active
- 1998-10-07 WO PCT/FR1998/002137 patent/WO1999019325A1/fr not_active Ceased
- 1998-10-07 AT AT98947615T patent/ATE212631T1/de active
- 1998-10-07 RU RU2000109298/04A patent/RU2203281C2/ru not_active IP Right Cessation
- 1998-10-07 DE DE69803689T patent/DE69803689T2/de not_active Expired - Lifetime
- 1998-10-07 NZ NZ503829A patent/NZ503829A/en not_active IP Right Cessation
- 1998-10-07 PL PL98339764A patent/PL186998B1/pl not_active IP Right Cessation
- 1998-10-07 US US09/529,077 patent/US6221879B1/en not_active Expired - Fee Related
- 1998-10-07 EE EEP200000207A patent/EE04347B1/et not_active IP Right Cessation
- 1998-10-07 CA CA002305468A patent/CA2305468C/en not_active Expired - Fee Related
- 1998-10-07 SI SI9830132T patent/SI1021442T1/xx unknown
- 1998-10-07 EP EP98947615A patent/EP1021442B1/fr not_active Expired - Lifetime
- 1998-10-07 KR KR1020007003811A patent/KR20010015717A/ko not_active Ceased
- 1998-10-07 CN CNB988119404A patent/CN1140526C/zh not_active Expired - Fee Related
- 1998-10-07 BR BR9812752-7A patent/BR9812752A/pt not_active Application Discontinuation
- 1998-10-07 AU AU94468/98A patent/AU746935B2/en not_active Ceased
- 1998-10-07 IL IL13552098A patent/IL135520A0/xx active IP Right Grant
- 1998-10-07 PT PT98947615T patent/PT1021442E/pt unknown
- 1998-10-08 CO CO98058540A patent/CO5011097A1/es unknown
- 1998-10-08 TW TW087116738A patent/TW444014B/zh not_active IP Right Cessation
2000
- 2000-04-06 IL IL135520A patent/IL135520A/en not_active IP Right Cessation
- 2000-04-07 BG BG104309A patent/BG64859B1/bg unknown
- 2000-04-07 NO NO20001810A patent/NO325170B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
TR200000942T2 (tr)	2000-09-21
NZ503829A (en)	2002-03-28
JP2001519431A (ja)	2001-10-23
EE04347B1 (et)	2004-08-16
NO20001810L (no)	2000-06-09
PL186998B1 (pl)	2004-04-30
UA58476C2 (uk)	2003-08-15
SK283080B6 (sk)	2003-02-04
CA2305468C (en)	2007-09-25
BG104309A (en)	2001-05-31
AR017300A1 (es)	2001-09-05
AU9446898A (en)	1999-05-03
CO5011097A1 (es)	2001-02-28
TW444014B (en)	2001-07-01
RU2203281C2 (ru)	2003-04-27
BR9812752A (pt)	2000-08-29
CZ290679B6 (cs)	2002-09-11
IL135520A0 (en)	2001-05-20
CN1281455A (zh)	2001-01-24
KR20010015717A (ko)	2001-02-26
SK5042000A3 (en)	2001-03-12
SI1021442T1 (en)	2002-08-31
CA2305468A1 (en)	1999-04-22
NO20001810D0 (no)	2000-04-07
ES2171306T3 (es)	2002-09-01
US6221879B1 (en)	2001-04-24
DE69803689T2 (de)	2002-10-10
WO1999019325A1 (fr)	1999-04-22
PL339764A1 (en)	2001-01-02
HUP0102086A3 (en)	2002-09-30
ATE212631T1 (de)	2002-02-15
EP1021442A1 (fr)	2000-07-26
NO325170B1 (no)	2008-02-11
PT1021442E (pt)	2002-06-28
CN1140526C (zh)	2004-03-03
DK1021442T3 (da)	2002-05-13
EP1021442B1 (fr)	2002-01-30
HK1029108A1 (en)	2001-03-23
HUP0102086A2 (hu)	2001-12-28
BG64859B1 (bg)	2006-07-31
IL135520A (en)	2007-07-24
AU746935B2 (en)	2002-05-09
DE69803689D1 (de)	2002-03-14
JP4505135B2 (ja)	2010-07-21
CZ20001278A3 (cs)	2000-07-12

Legal Events

Date	Code	Title	Description
2005-02-15	HC1A	Change of owner name
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2013-06-17	MM4A	Lapsed by not paying the annual fees	Effective date: 20121007

Publication	Publication Date	Title
FI955235A7 (fi)	1996-05-03	Oksatsolidiinionijohdannaiset, niiden valmistus ja käyttö
EE9900147A (et)	1999-12-15	Oksadiasoolid, nende saamismeetodid ja kasutamine ravimitena
EE200000037A (et)	2000-10-16	Atsüülpiperasinüülpürimidiinide derivaadid, nende valmistamine ja kasutamine ravimitena
FI954763A7 (fi)	1996-04-08	Oksiinijohdannaiset, niiden valmistus ja niiden terapeuttinen käyttö
EE05000B1 (et)	2008-04-15	2'-asendatud 1,1'-bifenüül-2-karboksamiidid, nende kasutamine ja farmatseutilised preparaadid
FI944600A7 (fi)	1995-04-05	Imidatsol-4-yylipiperidiinijohdannaisia, niiden valmistus ja niiden käyttö terapiassa
FI20051072L (fi)	2005-10-24	Polyamidi-oligonukleotidijohdoksia, niiden valmistus ja niiden käyttö
FI914611A7 (fi)	1992-04-03	2-aminopyrimidiini-4-karboksamidijohdannaiset, niiden valmistus ja terapeuttinen käyttö
EE9700288A (et)	1998-04-15	Asatsükloalkaani derivaadid, nende valmistamine ja kasutamine ravis
FI941068A7 (fi)	1994-09-09	Bentsoksatsiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö
EE200000056A (et)	2000-10-16	4-okso-3,5-dihüdro-4H-püridasino[4.5-b]indool-1-etaanamiidi derivaadid, nende valmistamine ja kasutamine raviks
EE9900218A (et)	1999-12-15	1,4-diasabitsüklo[2.2.2]okt-2-üülmetüülbensoaadi derivaadid, nende valmistamine ja kasutamine raviks
EE200000207A (et)	2001-04-16	8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, nende valmistamine ja terapeutiline kasutamine
FI940425A7 (fi)	1994-11-04	Modifioidut oligodeoksiribonukleotidit, niiden valmistus ja niiden terapeuttinen käyttö
EE9800451A (et)	1999-06-15	Uued imidasotriasolopürimidiinid, nende valmistamismeetod ja kasutamine ravimainetena
EE9800333A (et)	1999-04-15	Uued furaandiarüülmetülideeni derivaadid, nende valmistamise meetod ja kasutamine teraapias
FI970750L (fi)	1997-03-13	Indoli-2,3-dioni-3-oksimijohdannaisia, niiden valmistus ja käyttö
EE200000018A (et)	2000-08-15	6-pürrolidiin-2-üülpüridiinid, nende valmistamine ja terapeutiline kasutamine
FI941963A7 (fi)	1994-10-29	Pyridiinijohdannaiset, niiden valmistus ja käyttö
FI954141L (fi)	1996-03-06	Oksatsolokinolonijohdannaiset, niiden valmistus ja niiden käyttö terapiassa
EE03441B1 (et)	2001-06-15	5-naftalen-1-üül-1,3-dioksaani derivaadid, nende valmistamine ja terapeutiline kasutamine
FI965172A7 (fi)	1997-02-21	Uusia amido-kinoksaliinidioneja, niiden valmistus ja käyttö
FI941214A7 (fi)	1994-09-16	Bentsimidatsolin johdannaisia, niiden valmistus ja käyttö
FI942265L (fi)	1994-11-18	2-aminopyratsin-5-karboksamidijohdannaiset, niiden valmistus ja terapeuttinen käyttö
EE9900560A (et)	2000-06-15	5-naftaleen-1-üül-1,3-dioksaani derivaadid, nende valmistamine ja terapeutiline kasutamine