EG11358A - Process for preparing indole derivatives - Google Patents

Process for preparing indole derivatives

Info

Publication number: EG11358A
Authority: EG; Egypt
Prior art keywords: indole derivatives; preparing indole; preparing; derivatives; indole
Prior art date: 1971-11-03

Application number

EG446/72A

Other languages

English (en)

Original Assignee

Ici Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-11-03

Filing date

1972-10-29

Publication date

1977-02-28

1972-10-29 Application filed by Ici Ltd filed Critical Ici Ltd

1977-02-28 Application granted granted Critical

1977-02-28 Publication of EG11358A publication Critical patent/EG11358A/xx

Links

229940054051 antipsychotic indole derivative Drugs 0.000 title 1
150000002475 indoles Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

EG446/72A 1971-11-03 1972-10-29 Process for preparing indole derivatives EG11358A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB1811672A GB1356834A (en)	1971-11-03	1971-11-03	Indole derivatives
GB1811672		1972-04-19
GB3076772		1972-06-30

Publications (1)

Publication Number	Publication Date
EG11358A true EG11358A (en)	1977-02-28

Family

ID=27257588

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG446/72A EG11358A (en)	1971-11-03	1972-10-29	Process for preparing indole derivatives

Country Status (17)

Country	Link
US (1)	US3884919A (2)
JP (1)	JPS4856667A (2)
AR (3)	AR198064A1 (2)
BE (1)	BE790679A (2)
CA (1)	CA983932A (2)
CH (1)	CH577499A5 (2)
DD (1)	DD105611A5 (2)
DE (1)	DE2253927A1 (2)
EG (1)	EG11358A (2)
ES (2)	ES408226A1 (2)
FR (1)	FR2158464B1 (2)
GB (1)	GB1356834A (2)
HU (1)	HU169711B (2)
IE (1)	IE37998B1 (2)
IL (1)	IL40521A (2)
NL (1)	NL7214807A (2)
SE (1)	SE384856B (2)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4022780A (en) *	1973-03-06	1977-05-10	Imperial Chemical Industries Limited	Process for the manufacture of indole derivatives
FR2421900A1 (fr) *	1977-03-17	1979-11-02	Sauba Lab	Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques
US4316847A (en) *	1979-07-30	1982-02-23	Hoffmann-La Roche Inc.	Pyrroles and pyrrolidines
US4459227A (en) *	1981-03-02	1984-07-10	Duke University	Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones
BR9506936A (pt) *	1994-02-23	1997-09-09	Pfizer	Derivados de quinazolina substituídos com 4-heterociclila processos para sua preparaçao e seu uso como agentes anticancerosos
US6252084B1 (en) *	1994-03-15	2001-06-26	Eli Lilly And Company	1H-indole-3-acetamide sPLA2 inhibitors
EE200000488A (et) *	1998-02-25	2002-02-15	Genetics Institute, Inc.	Fosfolipaasensüümide inhibiitorid ja farmatseutilised kompositsioonid
US6500853B1 (en)	1998-02-28	2002-12-31	Genetics Institute, Llc	Inhibitors of phospholipase enzymes
SE0200411D0 (sv) *	2002-02-05	2002-02-05	Astrazeneca Ab	Novel use
SE0200356D0 (sv) *	2002-02-05	2002-02-05	Astrazeneca Ab	Novel use
TW200307542A (en)	2002-05-30	2003-12-16	Astrazeneca Ab	Novel compounds
SE0201635D0 (sv)	2002-05-30	2002-05-30	Astrazeneca Ab	Novel compounds
SE0202241D0 (sv)	2002-07-17	2002-07-17	Astrazeneca Ab	Novel Compounds
SE0301010D0 (sv) *	2003-04-07	2003-04-07	Astrazeneca Ab	Novel compounds
SE0301009D0 (sv) *	2003-04-07	2003-04-07	Astrazeneca Ab	Novel compounds
DE60303238T2 (de)	2003-04-25	2006-09-14	Actimis Pharmaceuticals, Inc., La Jolla	Pyrimidin-Essigsäure Derivate geeignet zur Behandlung von CRTH2-bedingten Krankheiten
CA2524221A1 (en) *	2003-04-30	2004-11-18	The Institutes For Pharmaceutical Discovery, Llc	Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
SE0301569D0 (sv)	2003-05-27	2003-05-27	Astrazeneca Ab	Novel compounds
SE0302232D0 (sv) *	2003-08-18	2003-08-18	Astrazeneca Ab	Novel Compounds
SA04250253B1 (ar)	2003-08-21	2009-11-10	استرازينيكا ايه بي	احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
GB0324763D0 (en)	2003-10-23	2003-11-26	Oxagen Ltd	Use of compounds in therapy
SE0303180D0 (sv)	2003-11-26	2003-11-26	Astrazeneca Ab	Novel compounds
CA2551778C (en)	2004-01-31	2013-10-22	Actimis Pharmaceuticals, Inc.	Imidazo[1,2-c]pyrimidinylacetic acid derivatives
GB0415320D0 (en)	2004-07-08	2004-08-11	Astrazeneca Ab	Novel compounds
GB0418830D0 (en)	2004-08-24	2004-09-22	Astrazeneca Ab	Novel compounds
JP5208510B2 (ja)	2004-11-23	2013-06-12	アストラゼネカ・アクチエボラーグ	呼吸器疾患の処置に有用なフェノキシ酢酸誘導体
GB0500604D0 (en)	2005-01-13	2005-02-16	Astrazeneca Ab	Novel process
TW200745003A (en)	2005-10-06	2007-12-16	Astrazeneca Ab	Novel compounds
US8148572B2 (en)	2005-10-06	2012-04-03	Astrazeneca Ab	Compounds
CN101454284A (zh)	2006-05-26	2009-06-10	阿斯利康(瑞典)有限公司	联芳基或芳基-杂芳基取代的吲哚类化合物
US7999119B2 (en)	2006-07-22	2011-08-16	Oxagen Limited	Compounds having CRTH2 antagonist activity
UA100983C2 (ru)	2007-07-05	2013-02-25	Астразенека Аб	Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
ATE547407T1 (de)	2007-09-25	2012-03-15	Actimis Pharmaceuticals Inc	Alkylthiopyrimidine als crth2-antagonisten
WO2009042139A1 (en)	2007-09-25	2009-04-02	Actimis Pharmaceuticals, Inc.	2-s-benzyl substituted pyrimidines as crth2 antagonists
US7750027B2 (en)	2008-01-18	2010-07-06	Oxagen Limited	Compounds having CRTH2 antagonist activity
AU2009204700B2 (en)	2008-01-18	2013-07-04	Atopix Therapeutics Limited	Compounds having CRTH2 antagonist activity
EP2265581A1 (en)	2008-01-22	2010-12-29	Oxagen Limited	Compounds having crth2 antagonist activity
JP2011509991A (ja)	2008-01-22	2011-03-31	オキサジェンリミテッド	Ｃｒｔｈ２アンタゴニスト活性を有する化合物
GB201322273D0 (en)	2013-12-17	2014-01-29	Atopix Therapeutics Ltd	Process
GB201407807D0 (en)	2014-05-02	2014-06-18	Atopix Therapeutics Ltd	Polymorphic form
GB201407820D0 (en)	2014-05-02	2014-06-18	Atopix Therapeutics Ltd	Polymorphic form
JOP20210060A1 (ar) *	2018-10-05	2023-01-30	Vertex Pharma	معدلات لمضاد تريبسين ألفا-1

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL125443C (2) *	1963-06-06
US3679692A (en) *	1969-10-01	1972-07-25	Mead Johnson & Co	Iminomethylindolines

0
- BE BE790679D patent/BE790679A/xx unknown
1971
- 1971-11-03 GB GB1811672A patent/GB1356834A/en not_active Expired
1972
- 1972-09-28 IE IE1320/72A patent/IE37998B1/xx unknown
- 1972-09-29 CA CA152,944A patent/CA983932A/en not_active Expired
- 1972-10-06 IL IL40521A patent/IL40521A/xx unknown
- 1972-10-10 US US296202A patent/US3884919A/en not_active Expired - Lifetime
- 1972-10-27 AR AR244863A patent/AR198064A1/es active
- 1972-10-29 EG EG446/72A patent/EG11358A/xx active
- 1972-11-02 NL NL7214807A patent/NL7214807A/xx unknown
- 1972-11-02 JP JP47110172A patent/JPS4856667A/ja active Pending
- 1972-11-02 DD DD166646A patent/DD105611A5/xx unknown
- 1972-11-02 CH CH1597672A patent/CH577499A5/xx not_active IP Right Cessation
- 1972-11-02 SE SE7214215A patent/SE384856B/xx unknown
- 1972-11-02 FR FR7238836A patent/FR2158464B1/fr not_active Expired
- 1972-11-03 DE DE2253927A patent/DE2253927A1/de active Pending
- 1972-11-03 HU HUIE540A patent/HU169711B/hu unknown
- 1972-11-03 ES ES408226A patent/ES408226A1/es not_active Expired
1973
- 1973-07-31 AR AR249382A patent/AR203627A1/es active
- 1973-07-31 AR AR249381A patent/AR203626A1/es active
1975
- 1975-04-30 ES ES437331A patent/ES437311A1/es not_active Expired

Also Published As

Publication number	Publication date
ES437311A1 (es)	1977-04-01
AR198064A1 (es)	1974-05-31
IL40521A0 (en)	1972-12-29
SE384856B (sv)	1976-05-24
US3884919A (en)	1975-05-20
JPS4856667A (2)	1973-08-09
CA983932A (en)	1976-02-17
NL7214807A (2)	1973-05-07
IL40521A (en)	1975-06-25
GB1356834A (en)	1974-06-19
FR2158464A1 (2)	1973-06-15
AR203626A1 (es)	1975-09-30
HU169711B (2)	1977-02-28
DE2253927A1 (de)	1973-05-10
IE37998L (en)	1973-05-03
AR203627A1 (es)	1975-09-30
FR2158464B1 (2)	1976-07-02
ES408226A1 (es)	1976-02-01
DD105611A5 (2)	1974-05-05
CH577499A5 (2)	1976-07-15
BE790679A (fr)	1973-04-27
IE37998B1 (en)	1977-12-07

Publication	Publication Date	Title
EG11358A (en)	1977-02-28	Process for preparing indole derivatives
YU213771A (en)	1979-04-30	Process for preparing phenyl-imidazolyl-alkanylic derivatives
YU35123B (en)	1980-09-25	Process for preparing imidazole derivatives
YU208471A (en)	1979-12-31	Process for preparing novel oxazolo-or thiazoloazepine derivatives
YU35354B (en)	1980-12-31	Process for obtaining isoindoline derivatives
YU216872A (en)	1980-09-25	Process for preparing cinnamoyl-5-benzofuran derivatives
YU211971A (en)	1979-07-10	Process for preparing novel thio-piperidine derivatives
YU55774A (en)	1982-06-30	Process for preparing indole derivatives
CS180587B2 (en)	1978-01-31	Process for preparing phthalazone derivatives
YU205772A (en)	1980-06-30	Process for obtaining 5-acyl-imino-stilbene derivatives
YU35249B (en)	1980-10-31	Process for preparing novel - dialkylaminoalkoxy-6-dimethoxy-4,7-benzofuran derivatives
YU34519B (en)	1979-09-10	Process for preparing indole derivatives
IL36143A (en)	1974-03-14	Process for preparing n-dimethylamino-benzopyrone derivatives
YU127171A (en)	1979-12-31	Process for preparing phenylaminoethanol derivatives
YU211471A (en)	1979-12-31	Process for preparing triazolobenzodiazepine-5n-oxide derivatives
CA994778A (en)	1976-08-10	Process for preparing indole derivatives
YU324572A (en)	1981-08-31	Process for obtaining halophenylthioacetamidocephalosporine derivatives
YU17680A (en)	1981-04-30	Process for preparing novel imidazole derivatives
YU35021B (en)	1980-06-30	Process for preparing lumilysergol derivatives
YU34617B (en)	1979-12-31	Process for preparing indole derivatives
YU124772A (en)	1982-02-28	Process for preparing new 3-hydrazinopyridazine derivatives
CA871713A (en)	1971-05-25	Process for preparing hydroxyisoquinuclidine derivatives
YU34980B (en)	1980-06-30	Process for preparing novel p-amino-phenol derivatives
YU252671A (en)	1982-06-30	Process for preparing hydantoin derivatives
YU177072A (en)	1982-02-25	Process for preparing benzodiazepine derivatives