EG18104A - Imidazoquinoline antithrombogenic cardiotonic agent - Google Patents

Imidazoquinoline antithrombogenic cardiotonic agent

Info

Publication number: EG18104A
Authority: EG; Egypt
Prior art keywords: imidazoquinoline; antithrombogenic; cardiotonic agent; cardiotonic; agent
Prior art date: 1985-04-25

Application number

EG237/86A

Other languages

English (en)

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-25

Filing date

1986-04-23

Publication date

1992-09-30

1986-04-23 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1992-09-30 Application granted granted Critical

1992-09-30 Publication of EG18104A publication Critical patent/EG18104A/xx

Links

230000002965 anti-thrombogenic effect Effects 0.000 title 1
239000000496 cardiotonic agent Substances 0.000 title 1
SQQXRXKYTKFFSM-UHFFFAOYSA-N chembl1992147 Chemical compound OC1=C(OC)C(OC)=CC=C1C1=C(C)C(C(O)=O)=NC(C=2N=C3C4=NC(C)(C)N=C4C(OC)=C(O)C3=CC=2)=C1N SQQXRXKYTKFFSM-UHFFFAOYSA-N 0.000 title 1
229940124669 imidazoquinoline Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

EG237/86A 1985-04-25 1986-04-23 Imidazoquinoline antithrombogenic cardiotonic agent EG18104A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US72686985A	1985-04-25	1985-04-25
US06/832,212 US4668686A (en)	1985-04-25	1986-02-26	Imidazoquinoline antithrombrogenic cardiotonic agents

Publications (1)

Publication Number	Publication Date
EG18104A true EG18104A (en)	1992-09-30

Family

ID=27111398

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG237/86A EG18104A (en)	1985-04-25	1986-04-23	Imidazoquinoline antithrombogenic cardiotonic agent

Country Status (32)

Country	Link
US (1)	US4668686A (fr)
KR (1)	KR940000828B1 (fr)
CN (1)	CN1016175B (fr)
AT (1)	AT390257B (fr)
AU (1)	AU592983B2 (fr)
BE (1)	BE904671A (fr)
CA (1)	CA1298836C (fr)
CH (1)	CH675722A5 (fr)
CY (1)	CY1641A (fr)
DE (1)	DE3614132A1 (fr)
DK (3)	DK164868C (fr)
EG (1)	EG18104A (fr)
ES (3)	ES8708229A1 (fr)
FI (1)	FI83316C (fr)
FR (1)	FR2581065B1 (fr)
GB (1)	GB2174987B (fr)
GR (1)	GR861086B (fr)
HK (1)	HK64492A (fr)
HU (1)	HU195813B (fr)
IL (1)	IL78581A0 (fr)
IT (1)	IT1215651B (fr)
LU (1)	LU86406A1 (fr)
MY (1)	MY102086A (fr)
NL (1)	NL8601053A (fr)
NO (1)	NO163406C (fr)
NZ (1)	NZ215885A (fr)
OA (1)	OA08242A (fr)
PT (1)	PT82460B (fr)
SE (1)	SE461468B (fr)
SG (1)	SG29092G (fr)
SU (3)	SU1450746A3 (fr)
YU (1)	YU46054B (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4775674A (en) *	1986-05-23	1988-10-04	Bristol-Myers Company	Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) *	1986-07-08	1987-10-20	Bristol-Myers Company	7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4743607A (en) *	1987-05-29	1988-05-10	Merrell Dow Pharmaceuticals Inc.	Cardiotonic tricyclic imidazolones
US4803210A (en) *	1987-05-29	1989-02-07	Merrell Dow Pharmaceuticals Inc.	Cardiotonic tricyclic oxazolones
US4943573A (en) *	1989-11-01	1990-07-24	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE4035854C2 (de) *	1990-11-10	1996-10-02	Daimler Benz Ag	Vorrichtung zum Fangen und Ableiten des von einem Fahrzeugrad hochgeschleuderten Spritzwassers
PH31245A (en) *	1991-10-30	1998-06-18	Janssen Pharmaceutica Nv	1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5208237A (en) *	1992-04-03	1993-05-04	Bristol-Meyers Squibb Company	7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5196428A (en) *	1992-04-03	1993-03-23	Bristol-Myers Squibb Company	Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5158958A (en) *	1992-04-03	1992-10-27	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5348960A (en) *	1992-04-03	1994-09-20	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5552267A (en) *	1992-04-03	1996-09-03	The Trustees Of Columbia University In The City Of New York	Solution for prolonged organ preservation
TW593317B (en) *	1993-06-21	2004-06-21	Janssen Pharmaceutica Nv	Positive cardiac inotropic and lusitropic pyrroloquinolinone derivatives
AU695301B2 (en) *	1993-07-06	1998-08-13	Pfizer Inc.	Bicyclic tetrahydro pyrazolopyridines
TW574214B (en) *	1994-06-08	2004-02-01	Pfizer	Corticotropin releasing factor antagonists
US6664264B2 (en) *	2000-12-08	2003-12-16	3M Innovative Properties Company	Thioether substituted imidazoquinolines
MXPA06001669A (es)	2003-08-12	2006-04-28	3M Innovative Properties Co	Compuestos que contienen imidazo-oxima sustituidos.
NZ545412A (en)	2003-08-27	2008-12-24	Coley Pharm Group Inc	Aryloxy and arylalkyleneoxy substituted imidazoquinolines
JP2007504269A (ja)	2003-09-05	2007-03-01	スリーエムイノベイティブプロパティズカンパニー	Ｃｄ５＋ｂ細胞リンパ腫の治療方法
EP1673087B1 (fr) *	2003-10-03	2015-05-13	3M Innovative Properties Company	Imidazoquinolines a substitution alcoxy
US7544697B2 (en)	2003-10-03	2009-06-09	Coley Pharmaceutical Group, Inc.	Pyrazolopyridines and analogs thereof
CN1906192A (zh) *	2003-11-14	2007-01-31	3M创新有限公司	羟胺取代的咪唑环化合物
WO2005048933A2 (fr)	2003-11-14	2005-06-02	3M Innovative Properties Company	Composes d'un anneau d'imidazo substitues par oxime
AU2004293078B2 (en)	2003-11-25	2012-01-19	3M Innovative Properties Company	Substituted imidazo ring systems and methods
JP2007517035A (ja)	2003-12-29	2007-06-28	スリーエムイノベイティブプロパティズカンパニー	アリールアルケニルおよびアリールアルキニル置換されたイミダゾキノリン
EP1699788A2 (fr)	2003-12-30	2006-09-13	3M Innovative Properties Company	Sulfonamides d'imidazoquinolinyle, d'imidazopyridinyle et d'imidazonaphtyridinyle
US8697873B2 (en)	2004-03-24	2014-04-15	3M Innovative Properties Company	Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en)	2004-06-15	2011-09-13	3M Innovative Properties Company	Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006009826A1 (fr)	2004-06-18	2006-01-26	3M Innovative Properties Company	Thiazoloquinolines et thiazolonaphtyridines substitues par aryloxy et arylalkyleneoxy
WO2006038923A2 (fr)	2004-06-18	2006-04-13	3M Innovative Properties Company	Imidazonaphthyridines substituees par aryle
US7915281B2 (en)	2004-06-18	2011-03-29	3M Innovative Properties Company	Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
CN101056877B (zh) *	2004-09-14	2010-06-09	诺华疫苗和诊断公司	咪唑并喹啉化合物
JP5313502B2 (ja)	2004-12-30	2013-10-09	スリーエムイノベイティブプロパティズカンパニー	置換キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物
CA2592904C (fr)	2004-12-30	2015-04-07	3M Innovative Properties Company	Composes chiraux a cycle [1,2]imidazo[4,5] fusionne
JP2008530022A (ja)	2005-02-04	2008-08-07	コーリーファーマシューティカルグループ，インコーポレイテッド	免疫反応調節物質を含む水性ゲル処方物
EP1846405A2 (fr)	2005-02-11	2007-10-24	3M Innovative Properties Company	Composes cycliques imidazo 4,5-c substitues par oxime et hydroxylamine et procedes associes
CA2602683A1 (fr)	2005-04-01	2006-10-12	Coley Pharmaceutical Group, Inc.	Pyrazolopyridine-1,4-diamines et analogues associes
CA2602590A1 (fr)	2005-04-01	2006-10-12	Coley Pharmaceutical Group, Inc.	Composes cycliques 1-pyrazolo[3,4-c] substitues comme modulateurs de la biosynthese de cytokine destines au traitement d'infections virales et de maladies neoplastiques
WO2008008432A2 (fr)	2006-07-12	2008-01-17	Coley Pharmaceutical Group, Inc.	Composés à cycle [1,2] imidazo [4,5-c] fusionné chiral substitué et procédés correspondants
US8227603B2 (en)	2006-08-01	2012-07-24	Cytokinetics, Inc.	Modulating skeletal muscle
US8299248B2 (en)	2006-08-02	2012-10-30	Cytokinetics, Incorporated	Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
DK2069352T5 (en)	2006-08-02	2017-04-03	Cytokinetics Inc	SPECIFIC CHEMICAL UNITS, COMPOSITIONS AND PROCEDURES
EP2139478A4 (fr) *	2007-03-30	2010-05-05	Cytokinetics Inc	Entités chimiques, compositions et procédés
US10272082B2 (en)	2011-07-13	2019-04-30	Cytokinetics, Inc.	Combination ALS therapy
WO2024149378A1 (fr) *	2023-01-13	2024-07-18	上海超阳药业有限公司	Composé quinolinone et composé naphtyridinone et leur utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3932407A (en) *	1973-11-19	1976-01-13	Bristol-Myers Company	Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

1986
- 1986-02-26 US US06/832,212 patent/US4668686A/en not_active Expired - Fee Related
- 1986-03-26 CA CA000505136A patent/CA1298836C/fr not_active Expired - Fee Related
- 1986-04-18 NZ NZ215885A patent/NZ215885A/xx unknown
- 1986-04-21 AU AU56413/86A patent/AU592983B2/en not_active Ceased
- 1986-04-22 FI FI861684A patent/FI83316C/fi not_active IP Right Cessation
- 1986-04-22 IL IL78581A patent/IL78581A0/xx not_active IP Right Cessation
- 1986-04-23 CN CN86102747A patent/CN1016175B/zh not_active Expired
- 1986-04-23 EG EG237/86A patent/EG18104A/xx active
- 1986-04-24 BE BE0/216585A patent/BE904671A/fr not_active IP Right Cessation
- 1986-04-24 IT IT8620206A patent/IT1215651B/it active
- 1986-04-24 SU SU864027355A patent/SU1450746A3/ru active
- 1986-04-24 GB GB8610037A patent/GB2174987B/en not_active Expired
- 1986-04-24 ES ES554336A patent/ES8708229A1/es not_active Expired
- 1986-04-24 PT PT82460A patent/PT82460B/pt not_active IP Right Cessation
- 1986-04-24 NL NL8601053A patent/NL8601053A/xx not_active Application Discontinuation
- 1986-04-24 NO NO861617A patent/NO163406C/no unknown
- 1986-04-24 CH CH1679/86A patent/CH675722A5/de not_active IP Right Cessation
- 1986-04-24 GR GR861086A patent/GR861086B/el unknown
- 1986-04-24 DK DK190986A patent/DK164868C/da not_active IP Right Cessation
- 1986-04-24 SE SE8601907A patent/SE461468B/sv not_active IP Right Cessation
- 1986-04-24 FR FR868605966A patent/FR2581065B1/fr not_active Expired - Fee Related
- 1986-04-24 LU LU86406A patent/LU86406A1/fr unknown
- 1986-04-25 KR KR1019860003204A patent/KR940000828B1/ko not_active Expired - Lifetime
- 1986-04-25 OA OA58845A patent/OA08242A/xx unknown
- 1986-04-25 HU HU861723A patent/HU195813B/hu not_active IP Right Cessation
- 1986-04-25 AT AT0112186A patent/AT390257B/de not_active IP Right Cessation
- 1986-04-25 DE DE19863614132 patent/DE3614132A1/de not_active Ceased
1987
- 1987-02-27 SU SU874202071A patent/SU1470192A3/ru active
- 1987-05-14 ES ES557552A patent/ES8802521A1/es not_active Expired
- 1987-05-14 ES ES557551A patent/ES8801829A1/es not_active Expired
- 1987-06-23 YU YU116787A patent/YU46054B/sh unknown
- 1987-09-25 SU SU874203391A patent/SU1560056A3/ru active
- 1987-09-29 MY MYPI87002266A patent/MY102086A/en unknown
1991
- 1991-04-30 DK DK080291A patent/DK165248C/da not_active IP Right Cessation
- 1991-05-01 DK DK081091A patent/DK165249C/da not_active IP Right Cessation
1992
- 1992-03-10 SG SG290/92A patent/SG29092G/en unknown
- 1992-08-27 HK HK644/92A patent/HK64492A/xx unknown
- 1992-11-06 CY CY1641A patent/CY1641A/en unknown

Also Published As

Publication number	Publication date
FI861684A0 (fi)	1986-04-22
FI83316B (fi)	1991-03-15
DK80291A (da)	1991-04-30
PT82460B (pt)	1988-11-30
ES554336A0 (es)	1987-10-01
BE904671A (fr)	1986-10-24
DK165248C (da)	1993-03-22
DK81091A (da)	1991-05-01
DK165248B (da)	1992-10-26
YU116787A (en)	1988-04-30
FI83316C (fi)	1991-06-25
AU592983B2 (en)	1990-02-01
DK190986A (da)	1986-10-26
ES8801829A1 (es)	1988-02-16
NZ215885A (en)	1989-04-26
AU5641386A (en)	1986-10-30
KR860008177A (ko)	1986-11-12
CN1016175B (zh)	1992-04-08
SG29092G (en)	1992-05-15
GR861086B (en)	1986-09-01
MY102086A (en)	1992-03-31
ES8802521A1 (es)	1988-07-16
IT1215651B (it)	1990-02-22
SE461468B (sv)	1990-02-19
SU1450746A3 (ru)	1989-01-07
FR2581065A1 (fr)	1986-10-31
OA08242A (en)	1987-10-30
DK80291D0 (da)	1991-04-30
NL8601053A (nl)	1986-11-17
FR2581065B1 (fr)	1990-02-02
IL78581A0 (en)	1986-08-31
AT390257B (de)	1990-04-10
CN86102747A (zh)	1987-02-04
SE8601907L (sv)	1986-10-26
YU46054B (sh)	1992-12-21
DK190986D0 (da)	1986-04-24
CY1641A (en)	1992-11-06
ES557552A0 (es)	1988-07-16
DK165249C (da)	1993-03-22
GB8610037D0 (en)	1986-05-29
PT82460A (en)	1986-05-01
HK64492A (en)	1992-09-04
HU195813B (en)	1988-07-28
LU86406A1 (fr)	1986-11-05
DK164868B (da)	1992-08-31
FI861684L (fi)	1986-10-26
US4668686A (en)	1987-05-26
ATA112186A (de)	1989-09-15
ES8708229A1 (es)	1987-10-01
SE8601907D0 (sv)	1986-04-24
SU1560056A3 (ru)	1990-04-23
IT8620206A0 (it)	1986-04-24
CA1298836C (fr)	1992-04-14
CH675722A5 (fr)	1990-10-31
NO163406C (no)	1990-05-23
NO861617L (no)	1986-10-27
HUT42089A (en)	1987-06-29
DE3614132A1 (de)	1986-11-27
DK81091D0 (da)	1991-05-01
DK164868C (da)	1993-01-11
ES557551A0 (es)	1988-02-16
KR940000828B1 (ko)	1994-02-02
NO163406B (no)	1990-02-12
SU1470192A3 (ru)	1989-03-30
DK165249B (da)	1992-10-26
GB2174987A (en)	1986-11-19
GB2174987B (en)	1989-08-02

Publication	Publication Date	Title
OA08242A (en)	1987-10-30	Imidazoquinoline antithrombogenic cardiotonic agents
GB8518300D0 (en)	1985-08-29	Contrast agent
GB8522535D0 (en)	1985-10-16	Contrast agent
ZA863957B (en)	1987-01-28	Alfuzosine compositions and use
GB8612781D0 (en)	1986-07-02	Formulation
GB8612780D0 (en)	1986-07-02	Formulation
ZA832903B (en)	1984-01-25	1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
GB8600945D0 (en)	1986-02-19	Self-locking agent
GB8629568D0 (en)	1987-01-21	Therapeutic agent
GR862045B (en)	1986-12-24	Cardiotonic heterocyclocarbonyl-and acetyl-thiazolones
DE3665805D1 (en)	1989-11-02	Antimicrobial agent
ZA863029B (en)	1986-12-30	Imidazoquinoline antithrombogenic cardiotonic agents
ZA863645B (en)	1987-01-28	Yield-promoting agents
GB8513358D0 (en)	1985-07-03	Formulation
PH23175A (en)	1989-05-19	Cardiotonic aroylthiazolones
PH23182A (en)	1989-05-29	Cardiotonic alkanoylthiazolones
GB8525013D0 (en)	1985-11-13	Antidiarrhoel agents
DE3662058D1 (en)	1989-03-16	Leather-treating agent and its use
GB8529500D0 (en)	1986-01-08	Formulation
IE861087L (en)	1986-10-15	Imidazoquinoline cardiotonic agent
GB8529885D0 (en)	1986-01-15	Therapeutic agent
BG40893A1 (en)	1987-03-14	Modifying agent
PL257182A1 (en)	1987-07-13	Coat-forming agent
PL254372A1 (en)	1987-04-21	Dishwashing agent
PL253439A3 (en)	1987-01-12	Corrosion preventing agent