EG19302A - Compound with gastric acid inhibitory effect and process for its preparation - Google Patents
Compound with gastric acid inhibitory effect and process for its preparationInfo
- Publication number
- EG19302A EG19302A EG61989A EG61989A EG19302A EG 19302 A EG19302 A EG 19302A EG 61989 A EG61989 A EG 61989A EG 61989 A EG61989 A EG 61989A EG 19302 A EG19302 A EG 19302A
- Authority
- EG
- Egypt
- Prior art keywords
- compound
- preparation
- inhibitory effect
- gastric acid
- acid inhibitory
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 210000004211 gastric acid Anatomy 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- WYWZRXAYFXMLLI-UHFFFAOYSA-N 4-fluoro-2-[(4-methoxypyridin-2-yl)methylsulfinyl]-1h-benzimidazole Chemical compound COC1=CC=NC(CS(=O)C=2NC3=CC=CC(F)=C3N=2)=C1 WYWZRXAYFXMLLI-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Percussion Or Vibration Massage (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE19888804629A SE8804629D0 (sv) | 1988-12-22 | 1988-12-22 | New therapeutically active compounds |
| SE8902170A SE8902170D0 (sv) | 1989-06-16 | 1989-06-16 | Therapeutically active compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EG19302A true EG19302A (en) | 1994-11-30 |
Family
ID=26660387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EG61989A EG19302A (en) | 1988-12-22 | 1989-12-18 | Compound with gastric acid inhibitory effect and process for its preparation |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5025024A (cs) |
| EP (1) | EP0449935B1 (cs) |
| JP (1) | JP2793905B2 (cs) |
| KR (1) | KR910700248A (cs) |
| CN (1) | CN1028233C (cs) |
| AT (1) | ATE110723T1 (cs) |
| AU (1) | AU639429B2 (cs) |
| BG (1) | BG60101B2 (cs) |
| CA (1) | CA2005980C (cs) |
| CS (1) | CS276361B6 (cs) |
| DE (1) | DE68917937T2 (cs) |
| DK (1) | DK122191A (cs) |
| EG (1) | EG19302A (cs) |
| FI (1) | FI913034A7 (cs) |
| GR (1) | GR1000316B (cs) |
| HU (1) | HUT57204A (cs) |
| IE (1) | IE64199B1 (cs) |
| IL (1) | IL92799A (cs) |
| LV (1) | LV10267B (cs) |
| MY (1) | MY129946A (cs) |
| NO (1) | NO178336C (cs) |
| NZ (1) | NZ231874A (cs) |
| PH (1) | PH27446A (cs) |
| PL (1) | PL160767B1 (cs) |
| PT (1) | PT92649B (cs) |
| WO (1) | WO1990006924A1 (cs) |
| YU (1) | YU47338B (cs) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
| MXPA04007169A (es) * | 2002-01-25 | 2004-10-29 | Santarus Inc | Suministro transmucosal de inhibidores de bomba de protones. |
| JP2006518751A (ja) * | 2003-02-20 | 2006-08-17 | サンタラス インコーポレイティッド | 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物 |
| US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| TWI398273B (zh) * | 2003-07-18 | 2013-06-11 | Santarus Inc | 用於抑制酸分泌之醫藥調配物及其製備及使用之方法 |
| MXPA06000524A (es) * | 2003-07-18 | 2006-08-11 | Santarus Inc | Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido. |
| US20070292498A1 (en) * | 2003-11-05 | 2007-12-20 | Warren Hall | Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers |
| US8906940B2 (en) * | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US20090092658A1 (en) * | 2007-10-05 | 2009-04-09 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE418966B (sv) * | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
| SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| IN148930B (cs) * | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
| CH644116A5 (de) * | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
| SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| IL71664A (en) * | 1983-05-03 | 1987-11-30 | Byk Gulden Lomberg Chem Fab | Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same |
| JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| JPS6150979A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
| US4738975A (en) * | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
| SE8505112D0 (sv) * | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
| FI90544C (fi) * | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
| NZ234564A (en) * | 1986-11-21 | 1991-04-26 | Haessle Ab | 1-substituted benzimidazoles and pharmaceutical compositions |
| FI96860C (fi) * | 1987-06-17 | 1996-09-10 | Eisai Co Ltd | Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi |
-
1989
- 1989-12-18 IE IE405089A patent/IE64199B1/en not_active IP Right Cessation
- 1989-12-18 EG EG61989A patent/EG19302A/xx active
- 1989-12-19 NZ NZ231874A patent/NZ231874A/en unknown
- 1989-12-19 GR GR890100833A patent/GR1000316B/el unknown
- 1989-12-19 CA CA002005980A patent/CA2005980C/en not_active Expired - Lifetime
- 1989-12-19 IL IL9279989A patent/IL92799A/en not_active IP Right Cessation
- 1989-12-19 PH PH39731A patent/PH27446A/en unknown
- 1989-12-20 FI FI913034A patent/FI913034A7/fi not_active Application Discontinuation
- 1989-12-20 AU AU48132/90A patent/AU639429B2/en not_active Ceased
- 1989-12-20 AT AT90901073T patent/ATE110723T1/de not_active IP Right Cessation
- 1989-12-20 KR KR1019900701827A patent/KR910700248A/ko not_active Ceased
- 1989-12-20 EP EP90901073A patent/EP0449935B1/en not_active Expired - Lifetime
- 1989-12-20 WO PCT/SE1989/000739 patent/WO1990006924A1/en not_active Ceased
- 1989-12-20 US US07/453,960 patent/US5025024A/en not_active Expired - Lifetime
- 1989-12-20 DE DE68917937T patent/DE68917937T2/de not_active Expired - Fee Related
- 1989-12-20 JP JP2501536A patent/JP2793905B2/ja not_active Expired - Fee Related
- 1989-12-20 HU HU901095A patent/HUT57204A/hu not_active IP Right Cessation
- 1989-12-21 PT PT92649A patent/PT92649B/pt not_active IP Right Cessation
- 1989-12-21 YU YU242789A patent/YU47338B/sh unknown
- 1989-12-21 CN CN89109589A patent/CN1028233C/zh not_active Expired - Fee Related
- 1989-12-21 MY MYPI89001835A patent/MY129946A/en unknown
- 1989-12-22 PL PL1989282922A patent/PL160767B1/pl unknown
- 1989-12-22 CS CS897343A patent/CS276361B6/cs unknown
-
1991
- 1991-06-19 BG BG094657A patent/BG60101B2/bg unknown
- 1991-06-20 NO NO912414A patent/NO178336C/no unknown
- 1991-06-21 DK DK122191A patent/DK122191A/da unknown
-
1993
- 1993-06-28 LV LVP-93-691A patent/LV10267B/lv unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE8804629D0 (sv) | New therapeutically active compounds | |
| EP0221041A3 (en) | Benzimidazole derivatives, process for their preparation and their pharmaceutical use | |
| IE940326L (en) | Benzimidazole derivatives substituted with a radical group¹and their use for inhibiting gastric acid secretion | |
| IL92797A0 (en) | Therapeutical active substituted benzimidazole and process for its preparation | |
| EG19302A (en) | Compound with gastric acid inhibitory effect and process for its preparation | |
| JO1664B1 (en) | The compound has the effect of immobilizing gastric acid and the process of preparing it | |
| JO1653B1 (en) | The current benzimidazole is a therapeutically active method for preparing it | |
| JO1519B1 (en) | New compounds (new benzimidazole derivatives are effective as ulcers) | |
| JO1679B1 (en) | A new, therapeutically active compound and method for preparing it |