EG23802A - 2-Phenylpyran-4-one derivatives - Google Patents

2-Phenylpyran-4-one derivatives

Info

Publication number
EG23802A
EG23802A EG118999A EG118999A EG23802A EG 23802 A EG23802 A EG 23802A EG 118999 A EG118999 A EG 118999A EG 118999 A EG118999 A EG 118999A EG 23802 A EG23802 A EG 23802A
Authority
EG
Egypt
Prior art keywords
phenylpyran
derivatives
Prior art date
Application number
EG118999A
Other languages
English (en)
Inventor
Maria I Crespo
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES9802011A external-priority patent/ES2154561B1/es
Priority claimed from ES009900619A external-priority patent/ES2168895A1/es
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Application granted granted Critical
Publication of EG23802A publication Critical patent/EG23802A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EG118999A 1998-09-25 1999-09-25 2-Phenylpyran-4-one derivatives EG23802A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES9802011A ES2154561B1 (es) 1998-09-25 1998-09-25 Derivados de 2-fenilpiran-4-ona.
ES009900619A ES2168895A1 (es) 1999-03-26 1999-03-26 Derivados de 2-fenilpiran-4-ona.

Publications (1)

Publication Number Publication Date
EG23802A true EG23802A (en) 2007-08-22

Family

ID=26155180

Family Applications (1)

Application Number Title Priority Date Filing Date
EG118999A EG23802A (en) 1998-09-25 1999-09-25 2-Phenylpyran-4-one derivatives

Country Status (33)

Country Link
US (1) US6518303B2 (de)
EP (1) EP1115716B1 (de)
JP (1) JP4717211B2 (de)
KR (1) KR100806684B1 (de)
CN (1) CN1202104C (de)
AR (1) AR021826A1 (de)
AT (1) ATE230405T1 (de)
AU (1) AU765653B2 (de)
BG (1) BG65308B1 (de)
BR (1) BR9913939A (de)
CA (1) CA2345069C (de)
CO (1) CO5140127A1 (de)
CZ (1) CZ300357B6 (de)
DE (1) DE69904738T2 (de)
DK (1) DK1115716T3 (de)
EE (1) EE04812B1 (de)
EG (1) EG23802A (de)
ES (1) ES2190252T3 (de)
HU (1) HUP0104620A3 (de)
ID (1) ID28624A (de)
IL (1) IL142087A0 (de)
MX (1) MXPA01003069A (de)
MY (1) MY121793A (de)
NO (1) NO327987B1 (de)
NZ (1) NZ510625A (de)
PE (1) PE20001067A1 (de)
PL (1) PL346895A1 (de)
RU (1) RU2232158C2 (de)
SI (1) SI1115716T1 (de)
SK (1) SK286471B6 (de)
TR (1) TR200100852T2 (de)
TW (1) TW587079B (de)
WO (1) WO2000018753A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5261556A1 (es) 1999-12-08 2003-03-31 Pharmacia Corp Composiciones inhibidoras de ciclooxigenasa-2 que tiene rapido acceso de efecto terapeutico
PE20011333A1 (es) 2000-03-16 2002-01-16 Almirall Prodesfarma Ag Derivados de 2-fenilpiran-4-ona como inhibidores de ciclooxigenasa 2
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
ES2214130B1 (es) * 2003-02-13 2005-12-01 Almirall Prodesfarma, S.A. 2-3'-bipiridinas.
ES2213485B1 (es) * 2003-02-13 2005-12-16 Almirall Prodesfarma, S.A. Derivados de la 2-fenilpiran-4-ona.
ES2214129B1 (es) * 2003-02-13 2005-12-01 Almirall Prodesfarma, S.A. 3-fenilfuran-2-onas.
US20040220155A1 (en) * 2003-03-28 2004-11-04 Pharmacia Corporation Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
WO2005009342A2 (en) * 2003-07-16 2005-02-03 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
US20050119262A1 (en) * 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
US20050107350A1 (en) * 2003-08-22 2005-05-19 Pharmacia Corporation Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
WO2005023189A2 (en) * 2003-09-03 2005-03-17 Pharmacia Corporation Method of cox-2 selective inhibitor and nitric oxide-donating agent
WO2018049027A1 (en) 2016-09-07 2018-03-15 Trustees Of Tufts College Combination therapies using immuno-dash inhibitors and pge2 antagonists
IL305573A (en) 2021-03-15 2023-10-01 Saul Yedgar HYALURONIC ACID-CONJUGATED DIPALMITOYL PHOSPHATIDYL ETHANOLAMINE IN COMBINATION WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) FOR TREATING OR ALLEVIATING INFLAMMATORY DISEASES

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US304728A (en) * 1884-09-09 Maubice hellwig
CH524614A (de) * 1969-12-31 1972-06-30 Ciba Geigy Ag Verfahren zur Herstellung von neuen Imidazolderivaten
US3901908A (en) * 1970-12-28 1975-08-26 Ciba Geigy Corp 2-alkyl- and 2-cycloalkyl-4,5-bis-phenyl-imidazoles
US4304728A (en) * 1979-04-05 1981-12-08 Lilly Industries Limited 6-Substituted pyranone compounds and their use as pharmaceuticals
IL59748A (en) 1979-04-05 1983-11-30 Lilly Industries Ltd 5-substituted pyranone derivatives,their production and pharmaceutical compositions containing them
JPS5834446B2 (ja) * 1979-05-22 1983-07-27 三省製薬株式会社 消炎剤
JPH0768234B2 (ja) * 1989-12-14 1995-07-26 久光製薬株式会社 コウジ酸エステル誘導体
KR920702353A (ko) * 1990-06-29 1992-09-03 로버트 에이. 아미테이지 아테롬성 동맥경화증 및 혈전등 치료제인 2-아미노-6-페닐-4h-피란-4-온
JPH04173391A (ja) * 1990-11-07 1992-06-22 Sanyo Chem Ind Ltd 感熱記録用増感剤および感熱記録用材料
DE4103904C2 (de) * 1991-02-08 1995-06-14 Analyticon Ges Fuer Chemische Neue Arzneimittel aus Gamma-Pyronen, Gamma-Pyridonen sowie Gamma-Thiopyronen
US6048850A (en) 1992-09-22 2000-04-11 Young; Donald A. Method of inhibiting prostaglandin synthesis in a human host
EE9600044A (et) * 1993-11-19 1996-10-15 Parke, Davis & Company Püranooni derivaadid kui proteaasi inhibiitorid ja viirusevastased toimeained
US5521213A (en) * 1994-08-29 1996-05-28 Merck Frosst Canada, Inc. Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
US5541204A (en) 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
NZ304886A (en) 1995-04-04 1998-11-25 Glaxo Group Ltd Imidazo [1,2a] pyridine derivatives, preparation and pharmaceutical compositions thereof
ATE301457T1 (de) * 1995-06-12 2005-08-15 Searle & Co Mittel, enthaltend einen cyclooxygenase-2 inhibitor und einen 5-lipoxygenase inhibitor
BR9813998A (pt) * 1997-11-19 2000-09-26 Kowa Co Novos derivados de piridazina e produtos medicinais contendo os mesmos como ingredientes efetivos

Also Published As

Publication number Publication date
MY121793A (en) 2006-02-28
WO2000018753A1 (en) 2000-04-06
US6518303B2 (en) 2003-02-11
PE20001067A1 (es) 2000-10-23
AU6084799A (en) 2000-04-17
BG65308B1 (bg) 2008-01-31
NO20011512D0 (no) 2001-03-23
HUP0104620A3 (en) 2003-01-28
SI1115716T1 (en) 2003-06-30
HK1034961A1 (en) 2001-11-09
TW587079B (en) 2004-05-11
EE200100173A (et) 2002-08-15
BR9913939A (pt) 2001-06-12
EP1115716A1 (de) 2001-07-18
SK3702001A3 (en) 2001-12-03
DE69904738T2 (de) 2003-04-30
IL142087A0 (en) 2002-03-10
CN1324352A (zh) 2001-11-28
KR20010075369A (ko) 2001-08-09
AU765653B2 (en) 2003-09-25
CA2345069A1 (en) 2000-04-06
CN1202104C (zh) 2005-05-18
NO20011512L (no) 2001-05-25
PL346895A1 (en) 2002-03-11
DK1115716T3 (da) 2003-02-24
TR200100852T2 (tr) 2001-10-22
EE04812B1 (et) 2007-04-16
SK286471B6 (sk) 2008-11-06
BG105373A (en) 2001-11-30
MXPA01003069A (es) 2002-07-02
DE69904738D1 (de) 2003-02-06
ES2190252T3 (es) 2003-07-16
AR021826A1 (es) 2002-08-07
CO5140127A1 (es) 2002-03-22
KR100806684B1 (ko) 2008-02-26
CZ20011058A3 (cs) 2001-08-15
US20020045644A1 (en) 2002-04-18
HUP0104620A2 (hu) 2002-04-29
JP2002525364A (ja) 2002-08-13
JP4717211B2 (ja) 2011-07-06
ATE230405T1 (de) 2003-01-15
EP1115716B1 (de) 2003-01-02
RU2232158C2 (ru) 2004-07-10
CA2345069C (en) 2009-03-10
NO327987B1 (no) 2009-11-02
ID28624A (id) 2001-06-21
CZ300357B6 (cs) 2009-04-29
NZ510625A (en) 2002-12-20

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