EE9600044A - Püranooni derivaadid kui proteaasi inhibiitorid ja viirusevastased toimeained - Google Patents
Püranooni derivaadid kui proteaasi inhibiitorid ja viirusevastased toimeainedInfo
- Publication number
- EE9600044A EE9600044A EE9600044A EE9600044A EE9600044A EE 9600044 A EE9600044 A EE 9600044A EE 9600044 A EE9600044 A EE 9600044A EE 9600044 A EE9600044 A EE 9600044A EE 9600044 A EE9600044 A EE 9600044A
- Authority
- EE
- Estonia
- Prior art keywords
- protease inhibitors
- antiviral agents
- pyranone derivatives
- pyranone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Chemical Vapour Deposition (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15502893A | 1993-11-19 | 1993-11-19 | |
| US08/319,768 US5808062A (en) | 1993-11-19 | 1994-10-12 | Pyrone derivatives as protease inhibitors and antiviral agents |
| PCT/US1994/012367 WO1995014014A2 (en) | 1993-11-19 | 1994-10-26 | Pyrone derivatives as protease inhibitors and antiviral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE9600044A true EE9600044A (et) | 1996-10-15 |
Family
ID=26851948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EE9600044A EE9600044A (et) | 1993-11-19 | 1994-10-26 | Püranooni derivaadid kui proteaasi inhibiitorid ja viirusevastased toimeained |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0729466A1 (et) |
| JP (1) | JPH09505295A (et) |
| AU (1) | AU682417B2 (et) |
| BG (1) | BG62770B1 (et) |
| CA (1) | CA2174124A1 (et) |
| CZ (1) | CZ134396A3 (et) |
| EE (1) | EE9600044A (et) |
| FI (1) | FI962019A7 (et) |
| HR (1) | HRP940938A2 (et) |
| HU (1) | HUT74888A (et) |
| IL (1) | IL111671A0 (et) |
| NO (1) | NO962015D0 (et) |
| PL (1) | PL314484A1 (et) |
| RU (1) | RU2153497C2 (et) |
| SK (1) | SK63996A3 (et) |
| WO (1) | WO1995014014A2 (et) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2168895A1 (es) * | 1999-03-26 | 2002-06-16 | Almirall Prodesfarma Sa | Derivados de 2-fenilpiran-4-ona. |
| TW587079B (en) * | 1998-09-25 | 2004-05-11 | Almirall Prodesfarma Ag | 2-phenylpyran-4-one derivatives |
| ES2154561B1 (es) * | 1998-09-25 | 2001-12-01 | Almirall Prodesfarma Sa | Derivados de 2-fenilpiran-4-ona. |
| PE20011333A1 (es) | 2000-03-16 | 2002-01-16 | Almirall Prodesfarma Ag | Derivados de 2-fenilpiran-4-ona como inhibidores de ciclooxigenasa 2 |
| WO2017218633A1 (en) * | 2016-06-14 | 2017-12-21 | Bristol-Myers Squibb Company | 6-hydroxy-5-(phenyl/heteroarylsulfonyl)pyrimidin-4(1h)-one as apj agonists |
| ES2844184T3 (es) * | 2016-06-14 | 2021-07-21 | Bristol Myers Squibb Co | 4-hidroxi-3-sulfonilpiridin-2(1H)-onas como agonistas del receptor de APJ |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3724M (fr) * | 1963-12-04 | 1965-12-06 | Marcel Perrault | Médicament a base d'anisoyl-3 hydroxy-4 p. méthoxy-phényl-6α-pyrone. |
| US3818046A (en) * | 1972-12-18 | 1974-06-18 | Dow Chemical Co | Sulfur-containing hydroxy pyrones and alkali metal salts thereof |
| DE4308451A1 (de) * | 1992-09-10 | 1994-04-14 | Bayer Ag | 3-Aryl-pyron-Derivate |
| ZA938019B (en) * | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
| JP3372338B2 (ja) * | 1994-02-14 | 2003-02-04 | オリンパス光学工業株式会社 | 測距装置 |
-
1994
- 1994-10-26 RU RU96113056/04A patent/RU2153497C2/ru active
- 1994-10-26 EP EP95900457A patent/EP0729466A1/en not_active Withdrawn
- 1994-10-26 FI FI962019A patent/FI962019A7/fi unknown
- 1994-10-26 HU HU9601347A patent/HUT74888A/hu unknown
- 1994-10-26 EE EE9600044A patent/EE9600044A/et unknown
- 1994-10-26 SK SK639-96A patent/SK63996A3/sk unknown
- 1994-10-26 JP JP7514461A patent/JPH09505295A/ja active Pending
- 1994-10-26 WO PCT/US1994/012367 patent/WO1995014014A2/en not_active Ceased
- 1994-10-26 CZ CZ961343A patent/CZ134396A3/cs unknown
- 1994-10-26 PL PL94314484A patent/PL314484A1/xx unknown
- 1994-10-26 AU AU81276/94A patent/AU682417B2/en not_active Ceased
- 1994-10-26 CA CA002174124A patent/CA2174124A1/en not_active Abandoned
- 1994-11-17 IL IL11167194A patent/IL111671A0/xx unknown
- 1994-11-18 HR HR08/319,768A patent/HRP940938A2/hr not_active Application Discontinuation
-
1996
- 1996-05-03 BG BG100564A patent/BG62770B1/bg unknown
- 1996-05-15 NO NO962015A patent/NO962015D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2174124A1 (en) | 1995-05-26 |
| HUT74888A (en) | 1997-02-28 |
| FI962019L (fi) | 1996-05-20 |
| HU9601347D0 (en) | 1996-07-29 |
| WO1995014014A3 (en) | 1995-06-15 |
| CZ134396A3 (en) | 1996-08-14 |
| SK63996A3 (en) | 1996-11-06 |
| IL111671A0 (en) | 1995-01-24 |
| FI962019A7 (fi) | 1996-05-20 |
| FI962019A0 (fi) | 1996-05-13 |
| JPH09505295A (ja) | 1997-05-27 |
| EP0729466A1 (en) | 1996-09-04 |
| RU2153497C2 (ru) | 2000-07-27 |
| PL314484A1 (en) | 1996-09-16 |
| NO962015L (no) | 1996-05-15 |
| AU682417B2 (en) | 1997-10-02 |
| HRP940938A2 (en) | 1997-06-30 |
| WO1995014014A2 (en) | 1995-05-26 |
| NO962015D0 (no) | 1996-05-15 |
| AU8127694A (en) | 1995-06-06 |
| BG100564A (bg) | 1996-12-31 |
| BG62770B1 (bg) | 2000-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI962022L (fi) | 5,6-dihydropyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina | |
| DE69434977D1 (de) | HIV Protease Inhibitoren | |
| FI961599A7 (fi) | 1N-alkyyli-N-aryylipyrimidiiniamiineja ja niiden johdannaisia | |
| FI933277A7 (fi) | Amiinidioli proteaasi-inhibiittorit | |
| FI945434L (fi) | 4-markatpoasetyyliamino/2/bentsatsepinoni (3) johdannaisia ja niiden käyttö enkefalinaasi-inhibiittoreina | |
| FI950375A7 (fi) | c-AMP-fosfodiesteraasin ja TFN:n estäjät | |
| KR950704251A (ko) | 프롤릴 엔도펩티다아제 억제 활성을 갖는 화합물 및 그 약학적 용도(compound with prolyl endopeptdase inhibitor activity and pharmaceutical use thereof) | |
| FI970317A7 (fi) | Antiproliferatiivisina aineina ja Garft-inhibiittoreina käyttökelpoisia yhdisteitä | |
| ZA949147B (en) | Pyrone derivatives as protease inhibitors and antiviral agents | |
| FI962021L (fi) | 5,6-dihydropyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina | |
| FI962488L (fi) | HIV:n proteaasin inhibiittoreita | |
| ZA949148B (en) | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents | |
| FI942294A7 (fi) | Bentsopyraanijohdannaiset ja niiden käyttö | |
| FI20020270A7 (fi) | 4-aryyli-4-hydroksi-tetrahydropyraanit ja 3-aryyli-3--hydroksi-tetrahydrofuraanit 5-lipoksygenaasi-inhibiittoreina | |
| FI962019L (fi) | Pyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina | |
| FI962020L (fi) | Pyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina | |
| FI950303L (fi) | Pyridoindolobentsodiatsepiinit ja johdannaiset antipsykoottisina aineina | |
| FI970318L (fi) | Antiproliferatiivisina aineina ja Garft-inhibiitoreina käyttökelpoisia yhdisteitä | |
| SI0729465T1 (en) | Pyrone derivatives as protease inhibitors and antiviral agents | |
| DE69418656D1 (de) | 2-acyloxycephemderivate als elastaseinhibitoren | |
| ITMI930345A1 (it) | N-acil-peptidi inibitori delle protein-chinasi |