EG25699A - N-aryl piperidine substituted biphenylcarboxamides - Google Patents

N-aryl piperidine substituted biphenylcarboxamides

Info

Publication number: EG25699A
Authority: EG; Egypt
Prior art keywords: piperidine substituted; aryl piperidine; biphenylcarboxamides; substituted biphenylcarboxamides; aryl
Prior art date: 2002-08-12

Application number

EG2003080749A

Other languages

English (en)

Inventor

Lieven Meerpoel

Leo Jacobus Jozef Backx

Peter Walter Maria Roevens

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-12

Filing date

2003-08-02

Publication date

2012-05-22

2003-08-02 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2012-05-22 Application granted granted Critical

2012-05-22 Publication of EG25699A publication Critical patent/EG25699A/xx

Links

GTKIGDZXPDCIKR-UHFFFAOYSA-N 2-phenylbenzamide Chemical class NC(=O)C1=CC=CC=C1C1=CC=CC=C1 GTKIGDZXPDCIKR-UHFFFAOYSA-N 0.000 title 1
NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

EG2003080749A 2002-08-12 2003-08-02 N-aryl piperidine substituted biphenylcarboxamides EG25699A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02078309		2002-08-12

Publications (1)

Publication Number	Publication Date
EG25699A true EG25699A (en)	2012-05-22

Family

ID=31896911

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG2003080749A EG25699A (en)	2002-08-12	2003-08-02	N-aryl piperidine substituted biphenylcarboxamides

Country Status (31)

Country	Link
US (2)	US20060040989A1 (de)
EP (1)	EP1536796B1 (de)
JP (1)	JP4559856B2 (de)
KR (1)	KR101052204B1 (de)
CN (3)	CN101165052B (de)
AR (1)	AR040968A1 (de)
AT (1)	ATE385796T1 (de)
AU (1)	AU2003250215B2 (de)
BR (1)	BR0313377A (de)
CA (1)	CA2494208C (de)
CY (1)	CY1107945T1 (de)
DE (1)	DE60319097T2 (de)
DK (1)	DK1536796T3 (de)
EA (1)	EA008061B1 (de)
EG (1)	EG25699A (de)
ES (1)	ES2301873T3 (de)
HR (1)	HRP20050103B1 (de)
IL (1)	IL166795A (de)
IS (1)	IS2726B (de)
MX (1)	MXPA05001712A (de)
MY (1)	MY136632A (de)
NO (1)	NO329308B1 (de)
NZ (1)	NZ538680A (de)
PA (1)	PA8579901A1 (de)
PL (1)	PL212405B1 (de)
PT (1)	PT1536796E (de)
SI (1)	SI1536796T1 (de)
TW (1)	TWI342775B (de)
UA (1)	UA79300C2 (de)
WO (1)	WO2004017969A1 (de)
ZA (1)	ZA200501225B (de)

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US7754717B2 (en)	2005-08-15	2010-07-13	Amgen Inc.	Bis-aryl amide compounds and methods of use
EP1948629A1 (de)	2005-10-31	2008-07-30	Janssen Pharmaceutica N.V.	Substituierte piperazine und piperidine als modulatoren des neuropeptid-y2-rezeptors
PL2666859T3 (pl) *	2006-04-03	2019-09-30	Roche Innovation Center Copenhagen A/S	Kompozycja farmaceutyczna zawierająca antysensowne oligonukleotydy anty-miRNA
ES2715625T3 (es)	2006-04-03	2019-06-05	Roche Innovation Ct Copenhagen As	Composición farmacéutica que comprende oligonucleótidos antisentido anti-miARN
WO2008100423A1 (en) *	2007-02-09	2008-08-21	Sirtris Pharmaceuticals, Inc.	Gut microsomal triglyceride transport protein inhibitors
US8580756B2 (en) *	2007-03-22	2013-11-12	Santaris Pharma A/S	Short oligomer antagonist compounds for the modulation of target mRNA
EP2126079A1 (de) *	2007-03-22	2009-12-02	Santaris Pharma A/S	Rna-antagonistenverbindungen zur hemmung der apo-b100-expression
AU2008292091A1 (en) *	2007-08-30	2009-03-05	Santaris Pharma A/S	RNA antagonist compounds for the modulation of FABP4/aP2
MX2010002885A (es) *	2007-09-20	2010-04-01	Amgen Inc	Derivados de acido 1-(4-(bencilbenzamido)-bencil)-azetidin-3-carbo xilico y compuestos relacionados como moduladores de receptores de s1p para el tratamiento de trastornos inmunitarios.
DK2205737T3 (da)	2007-10-04	2013-05-21	Santaris Pharma As	Mikromirer
WO2009109665A1 (en) *	2008-03-07	2009-09-11	Santaris Pharma A/S	Pharmaceutical compositions for treatment of microrna related diseases
WO2010012667A1 (en)	2008-08-01	2010-02-04	Santaris Pharma A/S	Micro-rna mediated modulation of colony stimulating factors
WO2010122538A1 (en) *	2009-04-24	2010-10-28	Santaris Pharma A/S	Pharmaceutical compositions for treatment of hcv patients that are non-responders to interferon
EP2456870A1 (de)	2009-07-21	2012-05-30	Santaris Pharma A/S	Auf pcsk9 gerichtete antisense-oligomere
SG10201908122XA (en)	2013-06-27	2019-10-30	Roche Innovation Ct Copenhagen As	Antisense oligomers and conjugates targeting pcsk9
JP6594351B2 (ja)	2014-06-16	2019-10-23	ジョンソン、マッセイ、パブリック、リミテッド、カンパニー	新規中間体を含むアルキル化アリールピペラジン及びアルキル化アリールピペリジン化合物の製造方法

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GB0129015D0 (en) *	2001-12-04	2002-01-23	Glaxo Group Ltd	Compounds

2003
- 2003-05-08 UA UAA200501990A patent/UA79300C2/uk unknown
- 2003-08-02 EG EG2003080749A patent/EG25699A/xx active
- 2003-08-05 EA EA200500348A patent/EA008061B1/ru not_active IP Right Cessation
- 2003-08-05 DE DE60319097T patent/DE60319097T2/de not_active Expired - Lifetime
- 2003-08-05 EP EP03792260A patent/EP1536796B1/de not_active Expired - Lifetime
- 2003-08-05 AT AT03792260T patent/ATE385796T1/de active
- 2003-08-05 HR HRP20050103AA patent/HRP20050103B1/hr not_active IP Right Cessation
- 2003-08-05 MX MXPA05001712A patent/MXPA05001712A/es active IP Right Grant
- 2003-08-05 CN CN2007101866730A patent/CN101165052B/zh not_active Expired - Fee Related
- 2003-08-05 KR KR1020057000829A patent/KR101052204B1/ko not_active Expired - Fee Related
- 2003-08-05 ES ES03792260T patent/ES2301873T3/es not_active Expired - Lifetime
- 2003-08-05 WO PCT/EP2003/008694 patent/WO2004017969A1/en not_active Ceased
- 2003-08-05 CN CNA2007101866745A patent/CN101165053A/zh active Pending
- 2003-08-05 JP JP2004530089A patent/JP4559856B2/ja not_active Expired - Fee Related
- 2003-08-05 CN CNB03818592XA patent/CN100366252C/zh not_active Expired - Fee Related
- 2003-08-05 PT PT03792260T patent/PT1536796E/pt unknown
- 2003-08-05 SI SI200331203T patent/SI1536796T1/sl unknown
- 2003-08-05 DK DK03792260T patent/DK1536796T3/da active
- 2003-08-05 CA CA2494208A patent/CA2494208C/en not_active Expired - Fee Related
- 2003-08-05 BR BR0313377-0A patent/BR0313377A/pt not_active Application Discontinuation
- 2003-08-05 AU AU2003250215A patent/AU2003250215B2/en not_active Ceased
- 2003-08-05 US US10/524,051 patent/US20060040989A1/en not_active Abandoned
- 2003-08-05 NZ NZ538680A patent/NZ538680A/en not_active IP Right Cessation
- 2003-08-05 PL PL373379A patent/PL212405B1/pl unknown
- 2003-08-07 PA PA20038579901A patent/PA8579901A1/es unknown
- 2003-08-08 MY MYPI20033022A patent/MY136632A/en unknown
- 2003-08-11 AR ARP030102901A patent/AR040968A1/es not_active Application Discontinuation
- 2003-08-11 TW TW092121938A patent/TWI342775B/zh not_active IP Right Cessation
2004
- 2004-12-29 IS IS7622A patent/IS2726B/is unknown
2005
- 2005-01-31 NO NO20050563A patent/NO329308B1/no not_active IP Right Cessation
- 2005-02-10 ZA ZA200501225A patent/ZA200501225B/en unknown
- 2005-02-10 IL IL166795A patent/IL166795A/en unknown
2008
- 2008-05-13 CY CY20081100504T patent/CY1107945T1/el unknown
2009
- 2009-01-09 US US12/351,385 patent/US8258304B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US8258304B2 (en)	2012-09-04
PT1536796E (pt)	2008-05-13
EA200500348A1 (ru)	2005-08-25
TW200412954A (en)	2004-08-01
IL166795A (en)	2010-11-30
KR20050026483A (ko)	2005-03-15
CN1674900A (zh)	2005-09-28
CA2494208A1 (en)	2004-03-04
PL373379A1 (en)	2005-08-22
TWI342775B (en)	2011-06-01
CN101165053A (zh)	2008-04-23
ES2301873T3 (es)	2008-07-01
NO329308B1 (no)	2010-09-27
CN101165052B (zh)	2012-04-18
AU2003250215A1 (en)	2004-03-11
CA2494208C (en)	2011-05-10
SI1536796T1 (sl)	2008-08-31
EA008061B1 (ru)	2007-02-27
CN100366252C (zh)	2008-02-06
NZ538680A (en)	2006-01-27
US20060040989A1 (en)	2006-02-23
DK1536796T3 (da)	2008-06-09
UA79300C2 (en)	2007-06-11
CN101165052A (zh)	2008-04-23
MY136632A (en)	2008-11-28
IS2726B (is)	2011-03-15
EP1536796B1 (de)	2008-02-13
CY1107945T1 (el)	2013-09-04
IS7622A (is)	2004-12-29
DE60319097D1 (de)	2008-03-27
JP2006500371A (ja)	2006-01-05
DE60319097T2 (de)	2009-06-04
ATE385796T1 (de)	2008-03-15
KR101052204B1 (ko)	2011-07-29
EP1536796A1 (de)	2005-06-08
IL166795A0 (en)	2006-01-15
AU2003250215B2 (en)	2009-01-22
HRP20050103A2 (en)	2006-09-30
WO2004017969A1 (en)	2004-03-04
PA8579901A1 (es)	2005-03-03
HK1083451A1 (en)	2006-07-07
BR0313377A (pt)	2005-07-12
HRP20050103B1 (hr)	2013-09-30
JP4559856B2 (ja)	2010-10-13
NO20050563L (no)	2005-01-31
AR040968A1 (es)	2005-04-27
MXPA05001712A (es)	2005-04-19
ZA200501225B (en)	2006-07-26
US20090156623A1 (en)	2009-06-18
PL212405B1 (pl)	2012-09-28

Publication	Publication Date	Title
PL375220A1 (en)	2005-11-28	Piperidine derivatives
HUS1400037I1 (hu)	2017-08-28	Új 2-piridiletilbenzamid származékok
GB0219896D0 (en)	2002-10-02	Dihydropyridine derivatives
AP2004003119A0 (en)	2004-09-30	Substituted hydroxyethylamines
IL162765A0 (en)	2005-11-20	Piperidine derivatives
EG25699A (en)	2012-05-22	N-aryl piperidine substituted biphenylcarboxamides
GB0307666D0 (en)	2003-05-07	Swing
ZA200500294B (en)	2006-08-30	Novel 2-pyridylethylbenzamide derivative
PL373583A1 (en)	2005-09-05	Novel piperidine compound
PT1487778E (pt)	2012-07-26	Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
IL166740A0 (en)	2006-01-15	Substituted heterocyclylpyrimidines
GB2387414B (en)	2005-04-13	Hinges
GB0320207D0 (en)	2003-10-01	Methods
GB0221711D0 (en)	2002-10-30	Methods
AU2003264722A8 (en)	2004-03-11	Methods
PL377325A1 (pl)	2006-01-23	Podstawione benzodioksepiny
GB0204967D0 (en)	2002-04-17	Methods
GB0202213D0 (en)	2002-03-20	Methods
GB0211384D0 (en)	2002-06-26	Viscometers
GB0222276D0 (en)	2002-10-30	Methods
GB0213580D0 (en)	2002-07-24	Methods
GB0213579D0 (en)	2002-07-24	Methods
GB0200526D0 (en)	2002-02-27	Methods
SI1472256T1 (sl)	2006-04-30	Piperidinovi derivati
IL152801A0 (en)	2003-06-24	Swing