EP1853228A4 - Verfahren zur herstellung von mikrokugeln oder mikrokapseln - Google Patents

Verfahren zur herstellung von mikrokugeln oder mikrokapseln

Info

Publication number
EP1853228A4
EP1853228A4 EP06780513A EP06780513A EP1853228A4 EP 1853228 A4 EP1853228 A4 EP 1853228A4 EP 06780513 A EP06780513 A EP 06780513A EP 06780513 A EP06780513 A EP 06780513A EP 1853228 A4 EP1853228 A4 EP 1853228A4
Authority
EP
European Patent Office
Prior art keywords
microcapsules
microspheres
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06780513A
Other languages
English (en)
French (fr)
Other versions
EP1853228A2 (de
Inventor
Ajay Khopade
Alex George
Subhas Balaram Bhowmick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharma Advanced Research Co Ltd
Original Assignee
Sun Pharma Advanced Research Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharma Advanced Research Co Ltd filed Critical Sun Pharma Advanced Research Co Ltd
Publication of EP1853228A2 publication Critical patent/EP1853228A2/de
Publication of EP1853228A4 publication Critical patent/EP1853228A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
EP06780513A 2005-03-01 2006-03-01 Verfahren zur herstellung von mikrokugeln oder mikrokapseln Withdrawn EP1853228A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN231MU2005 2005-03-01
IN1182MU2005 2005-09-26
PCT/IN2006/000065 WO2006123359A2 (en) 2005-03-01 2006-03-01 A process of making microspheres

Publications (2)

Publication Number Publication Date
EP1853228A2 EP1853228A2 (de) 2007-11-14
EP1853228A4 true EP1853228A4 (de) 2012-07-18

Family

ID=37431677

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06780513A Withdrawn EP1853228A4 (de) 2005-03-01 2006-03-01 Verfahren zur herstellung von mikrokugeln oder mikrokapseln

Country Status (3)

Country Link
US (1) US20090104274A1 (de)
EP (1) EP1853228A4 (de)
WO (1) WO2006123359A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8034382B2 (en) * 2008-07-31 2011-10-11 The Board Of Trustees Of The University Of Arkansas Preparation method for biodegradable micro-particles containing drugs
WO2011087689A2 (en) * 2009-12-22 2011-07-21 Surmodics Pharmaceuticals,Inc. Emulsion-based process for preparing microparticles and workhead assembly for use with same
US8708159B2 (en) * 2011-02-16 2014-04-29 Oakwood Laboratories, Llc Manufacture of microspheres using a hydrocyclone
CN103191021A (zh) * 2012-01-10 2013-07-10 山东绿叶制药有限公司 一种连续生产微球的设备及其应用
EP2951241A4 (de) * 2013-01-29 2016-08-24 United Technologies Corp Klingenabriebmaterial
EP2951400B1 (de) 2013-01-29 2018-11-07 United Technologies Corporation Abriebsegment für rotorblätter, turbine mit einem abriebsegment für rotorblätter, und verwendung einer polymermatrix mit kohlenstoffnanoröhren als abriebmaterial in einer turbine.
CN103211773B (zh) * 2013-04-10 2014-11-05 上海丽珠制药有限公司 一种制备醋酸亮丙瑞林微球的方法
WO2015028060A1 (en) * 2013-08-29 2015-03-05 Evonik Industries Ag Process for preparing a bio-resorbable polyester in the form of a powder
IL305990B2 (en) * 2013-12-03 2025-12-01 Intra Cellular Therapies Inc Long-acting injectable composition comprising polymeric microspheres of heterocycle fused gamma-carboline compounds or a pharmaceutical composition for sustained or delayed release comprising the compounds and their use in the treatment of bipolar disorder i and/or bipolar ii disorder
WO2017199123A1 (en) 2016-05-17 2017-11-23 Ecole Polytechnique Federale De Lausanne (Epfl) Device and methods for shell phase removal of core-shell capsules
AU2018254225B2 (en) * 2017-04-19 2024-05-23 Nanomi B.V. Method and system for producing substantially mono-disperse particles of a substance
MX2020003681A (es) * 2017-09-26 2020-08-03 Nanomi B V Metodo para preparar microparticulas por tecnica de doble emulsion.
CN112236459A (zh) * 2018-04-23 2021-01-15 灰色视觉公司 改善的连续微粒制造
CN112708233B (zh) * 2019-10-25 2023-04-07 中国石油化工股份有限公司 聚合物微球-聚合物复合体系及其制备方法
CN111215017B (zh) * 2019-12-10 2021-06-25 山东省鲁洲食品集团有限公司 防止液体糊精储存过程中老化的装置及其方法
IT202000017191A1 (it) * 2020-07-15 2022-01-15 Xbrane Biopharma Ab Procedimento senza acqua per preparare una composizione farmaceutica per un rilascio più prolungato e controllato di triptorelina o di un suo sale
CN113318678B (zh) * 2021-05-19 2022-11-11 中国药科大学 一种调节微球干燥进程并降低残留溶剂的装置
CN113304246B (zh) * 2021-06-11 2022-04-08 四川大学 一种负载特拉万星的正电荷明胶微球的制备方法
CN113617305B (zh) * 2021-10-13 2022-03-18 北京蓝晶微生物科技有限公司 一种窄粒度分布的聚羟基脂肪酸酯微球及其制备方法
CN115386226B (zh) * 2022-08-25 2023-08-18 四川大学 一种聚醚砜抗氧化微球、其制备方法及用途
AU2023355823A1 (en) 2022-10-05 2025-04-17 Mireca Medicines Gmbh MICROPARTICLE AND IMPLANT FORMULATIONS FOR cGMP ANALOG THERAPY

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011009A1 (en) * 1993-10-22 1995-04-27 Genentech, Inc. Method for preparing microspheres comprising a fluidized bed drying step
WO2001078687A1 (en) * 2000-04-18 2001-10-25 Peptron Inc. Injectable sustained release pharmaceutical composition and processes for preparing the same
EP1277787A1 (de) * 2000-04-28 2003-01-22 Tanabe Seiyaku Co., Ltd. Verfahren zur herstellung von mikrosphären
WO2003013683A1 (en) * 2001-08-08 2003-02-20 Brown University Research Foundation Methods for micronization of hydrophobic drugs
US20040118007A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
EP1532985A1 (de) * 2002-06-25 2005-05-25 Takeda Pharmaceutical Company Limited Verfahren zur herstellung einer zusammensetzung mit verz gerter freisetzung
EP1537846A1 (de) * 2002-09-11 2005-06-08 Tanabe Seiyaku Co., Ltd. Verfahren zur herstellung von mikrokügelchen und gerät dafür

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478564A (en) * 1990-02-22 1995-12-26 Teva Pharmaceutical Industries, Ltd. Preparation of microparticles for controlled release of water-soluble substances
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5945126A (en) * 1997-02-13 1999-08-31 Oakwood Laboratories L.L.C. Continuous microsphere process
US20050214227A1 (en) * 1999-03-08 2005-09-29 Powderject Research Limited Microparticle formulations for sustained-release of bioactive compounds
AR023940A1 (es) * 2000-05-03 2002-09-04 Eriochem Sa Procedimiento para la produccion de microcapsulas de liberacion prolongada de peptidos solubles en agua
US20040022861A1 (en) * 2001-01-30 2004-02-05 Williams Robert O. Process for production of nanoparticles and microparticles by spray freezing into liquid

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011009A1 (en) * 1993-10-22 1995-04-27 Genentech, Inc. Method for preparing microspheres comprising a fluidized bed drying step
WO2001078687A1 (en) * 2000-04-18 2001-10-25 Peptron Inc. Injectable sustained release pharmaceutical composition and processes for preparing the same
EP1277787A1 (de) * 2000-04-28 2003-01-22 Tanabe Seiyaku Co., Ltd. Verfahren zur herstellung von mikrosphären
WO2003013683A1 (en) * 2001-08-08 2003-02-20 Brown University Research Foundation Methods for micronization of hydrophobic drugs
EP1532985A1 (de) * 2002-06-25 2005-05-25 Takeda Pharmaceutical Company Limited Verfahren zur herstellung einer zusammensetzung mit verz gerter freisetzung
EP1537846A1 (de) * 2002-09-11 2005-06-08 Tanabe Seiyaku Co., Ltd. Verfahren zur herstellung von mikrokügelchen und gerät dafür
US20040118007A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill

Also Published As

Publication number Publication date
WO2006123359A2 (en) 2006-11-23
WO2006123359A3 (en) 2007-07-26
US20090104274A1 (en) 2009-04-23
EP1853228A2 (de) 2007-11-14

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK YU

DAX Request for extension of the european patent (deleted)
RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: SUN PHARMA ADVANCED RESEARCH COMPANY LTD

A4 Supplementary search report drawn up and despatched

Effective date: 20120620

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Ipc: A61K 9/16 20060101AFI20120614BHEP

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