MX2020003681A - Metodo para preparar microparticulas por tecnica de doble emulsion. - Google Patents
Metodo para preparar microparticulas por tecnica de doble emulsion.Info
- Publication number
- MX2020003681A MX2020003681A MX2020003681A MX2020003681A MX2020003681A MX 2020003681 A MX2020003681 A MX 2020003681A MX 2020003681 A MX2020003681 A MX 2020003681A MX 2020003681 A MX2020003681 A MX 2020003681A MX 2020003681 A MX2020003681 A MX 2020003681A
- Authority
- MX
- Mexico
- Prior art keywords
- phase
- preparing
- double emulsion
- microparticles
- preparing microparticles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Medicinal Preparation (AREA)
- Colloid Chemistry (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Abstract
Se proporcionan metodos para preparar microparticulas usando una tecnica de doble emulsion que combina una membrana y un micro tamiz. En particular, la presente invencion se refiere a un metodo para preparar microparticulas que comprende: preparar una primera fase que comprende un agente activo; preparar una segunda fase que comprende un vehiculo y un disolvente; pasar la primera fase y la segunda fase a traves de una membrana para formar una emulsion primaria; pasar la emulsion primaria a traves de un micro tamiz en una fase continua para formar una emulsion secundaria; y eliminar el disolvente para formar las microparticulas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2019632 | 2017-09-26 | ||
| PCT/NL2018/050636 WO2019066649A1 (en) | 2017-09-26 | 2018-09-26 | PROCESS FOR THE PREPARATION OF MICROPARTICLES BY A DOUBLE EMULSION TECHNIQUE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2020003681A true MX2020003681A (es) | 2020-08-03 |
Family
ID=60628132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020003681A MX2020003681A (es) | 2017-09-26 | 2018-09-26 | Metodo para preparar microparticulas por tecnica de doble emulsion. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11052046B2 (es) |
| EP (1) | EP3687503A1 (es) |
| JP (1) | JP2020535224A (es) |
| CN (1) | CN111315365A (es) |
| AU (2) | AU2018341389A1 (es) |
| BR (1) | BR112020006136A2 (es) |
| CA (1) | CA3077011A1 (es) |
| CL (1) | CL2020000793A1 (es) |
| CO (1) | CO2020004360A2 (es) |
| IL (1) | IL273560B (es) |
| JO (1) | JOP20200068B1 (es) |
| MX (1) | MX2020003681A (es) |
| SA (1) | SA520411598B1 (es) |
| WO (1) | WO2019066649A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12297148B2 (en) | 2021-11-02 | 2025-05-13 | Saudi Arabian Oil Company | Self-repairing cement including microcapsule-in-microcapsule material and designed swellable rubber and methods for fabricating same |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4389330A (en) | 1980-10-06 | 1983-06-21 | Stolle Research And Development Corporation | Microencapsulation process |
| PH19942A (en) | 1980-11-18 | 1986-08-14 | Sintex Inc | Microencapsulation of water soluble polypeptides |
| JPS60100516A (ja) | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
| CH660302A5 (fr) | 1984-10-17 | 1987-04-15 | Debiopharm Sa | Procede de micro-encapsulation en phase heterogene de substances medicamenteuses hydrosolubles. |
| GB2209937B (en) | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
| US5439688A (en) | 1989-07-28 | 1995-08-08 | Debio Recherche Pharmaceutique S.A. | Process for preparing a pharmaceutical composition |
| CH679207A5 (es) | 1989-07-28 | 1992-01-15 | Debiopharm Sa | |
| US5225205A (en) | 1989-07-28 | 1993-07-06 | Debiopharm S.A. | Pharmaceutical composition in the form of microparticles |
| EP0546174B1 (en) * | 1991-06-29 | 1997-10-29 | Miyazaki-Ken | Monodisperse single and double emulsions and production thereof |
| CH683149A5 (fr) | 1991-07-22 | 1994-01-31 | Debio Rech Pharma Sa | Procédé pour la préparation de microsphères en matériau polymère biodégradable. |
| JPH0558882A (ja) * | 1991-09-04 | 1993-03-09 | Yoshiaki Kawashima | ナノカプセルの製造法 |
| CH688269A5 (fr) | 1992-08-21 | 1997-07-15 | Debio Rech Pharma Sa | Broyeur ultra-centrifuge et sa mise en oeuvre pour le broyage cryogénique de matériau thermosensible. |
| US5945126A (en) | 1997-02-13 | 1999-08-31 | Oakwood Laboratories L.L.C. | Continuous microsphere process |
| NL1026261C2 (nl) | 2004-05-25 | 2005-11-28 | Nanomi B V | Sproei inrichting met een nozzleplaat voorzien van structuren ter bevordering van self-breakup, een nozzleplaat, alsmede werkwijzen ter vervaardiging en toepassing van een dergelijke nozzleplaat. |
| EP1853228A4 (en) * | 2005-03-01 | 2012-07-18 | Sun Pharma Advanced Res Co Ltd | METHOD FOR THE PRODUCTION OF MICROBALLS OR MICRO CAPSULES |
| JP4580801B2 (ja) * | 2005-03-29 | 2010-11-17 | 株式会社東芝 | 複合型微粒子の製造方法及び複合型微粒子の製造装置 |
| NO347209B1 (no) * | 2006-12-18 | 2023-07-03 | Takeda Pharmaceutical | Sammensetning med forlenget frigjøring og fremgangsmåte for å produsere det samme |
| EP2334288B1 (en) * | 2008-09-18 | 2021-05-19 | Evonik Corporation | Microencapsulation process with solvent and salt |
| WO2010085607A1 (en) * | 2009-01-23 | 2010-07-29 | Surmodics Pharmaceuticals, Inc. | Continuous double emulsion process for making microparticles |
| WO2011001780A1 (ja) * | 2009-07-02 | 2011-01-06 | コニカミノルタホールディングス株式会社 | 特定分散剤を含有する外水相を利用する二段階乳化法によるリポソームの製造方法、ならびに当該リポソームの製造方法を用いるリポソーム分散液またはその乾燥粉末の製造方法およびそれにより製造されるリポソーム分散液またはその乾燥粉末 |
| WO2011087689A2 (en) | 2009-12-22 | 2011-07-21 | Surmodics Pharmaceuticals,Inc. | Emulsion-based process for preparing microparticles and workhead assembly for use with same |
| CN102892406B (zh) * | 2010-01-19 | 2015-04-08 | 波利皮得有限公司 | 缓释核酸基质组合物 |
| RU2617057C2 (ru) * | 2010-03-26 | 2017-04-19 | Евоник Корпорейшн | Эмульсии для микрокапсулирования, содержащие биоразлагаемые поверхностно-активные блок-сополимеры в качестве стабилизаторов |
| KR101558083B1 (ko) * | 2014-04-07 | 2015-10-07 | 에스케이케미칼주식회사 | 약물함유 고분자미립구 제조방법 |
-
2018
- 2018-09-26 MX MX2020003681A patent/MX2020003681A/es unknown
- 2018-09-26 CN CN201880069934.7A patent/CN111315365A/zh active Pending
- 2018-09-26 AU AU2018341389A patent/AU2018341389A1/en not_active Abandoned
- 2018-09-26 US US16/651,050 patent/US11052046B2/en active Active
- 2018-09-26 WO PCT/NL2018/050636 patent/WO2019066649A1/en not_active Ceased
- 2018-09-26 EP EP18827267.8A patent/EP3687503A1/en active Pending
- 2018-09-26 CA CA3077011A patent/CA3077011A1/en active Pending
- 2018-09-26 JP JP2020538518A patent/JP2020535224A/ja active Pending
- 2018-09-26 BR BR112020006136-0A patent/BR112020006136A2/pt unknown
-
2020
- 2020-03-24 IL IL273560A patent/IL273560B/en unknown
- 2020-03-24 SA SA520411598A patent/SA520411598B1/ar unknown
- 2020-03-26 CL CL2020000793A patent/CL2020000793A1/es unknown
- 2020-04-13 CO CONC2020/0004360A patent/CO2020004360A2/es unknown
- 2020-04-27 JO JOJO/P/2020/0068A patent/JOP20200068B1/ar active
-
2024
- 2024-08-29 AU AU2024216428A patent/AU2024216428A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JOP20200068A1 (ar) | 2020-04-27 |
| CO2020004360A2 (es) | 2020-04-24 |
| AU2018341389A1 (en) | 2020-04-23 |
| CN111315365A (zh) | 2020-06-19 |
| EP3687503A1 (en) | 2020-08-05 |
| IL273560A (en) | 2020-05-31 |
| WO2019066649A1 (en) | 2019-04-04 |
| RU2020113100A3 (es) | 2021-11-25 |
| SA520411598B1 (ar) | 2022-11-30 |
| RU2020113100A (ru) | 2021-10-08 |
| CL2020000793A1 (es) | 2021-01-04 |
| AU2024216428A1 (en) | 2024-09-19 |
| JOP20200068B1 (ar) | 2024-04-18 |
| WO2019066649A8 (en) | 2019-05-31 |
| BR112020006136A2 (pt) | 2020-10-06 |
| US20200230061A1 (en) | 2020-07-23 |
| CA3077011A1 (en) | 2019-04-04 |
| US11052046B2 (en) | 2021-07-06 |
| IL273560B (en) | 2022-06-01 |
| JP2020535224A (ja) | 2020-12-03 |
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