EP2079704A4 - Composés thérapeutiques - Google Patents

Composés thérapeutiques

Info

Publication number
EP2079704A4
EP2079704A4 EP07755933A EP07755933A EP2079704A4 EP 2079704 A4 EP2079704 A4 EP 2079704A4 EP 07755933 A EP07755933 A EP 07755933A EP 07755933 A EP07755933 A EP 07755933A EP 2079704 A4 EP2079704 A4 EP 2079704A4
Authority
EP
European Patent Office
Prior art keywords
therapeutic compounds
therapeutic
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07755933A
Other languages
German (de)
English (en)
Other versions
EP2079704A2 (fr
Inventor
Edmond J Lavoie
Joseph E Rice
Leroy F Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rutgers State University of New Jersey
Rutgers Health
Original Assignee
Rutgers State University of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rutgers State University of New Jersey filed Critical Rutgers State University of New Jersey
Publication of EP2079704A2 publication Critical patent/EP2079704A2/fr
Publication of EP2079704A4 publication Critical patent/EP2079704A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EP07755933A 2006-04-25 2007-04-24 Composés thérapeutiques Withdrawn EP2079704A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79452506P 2006-04-25 2006-04-25
PCT/US2007/009862 WO2007127173A2 (fr) 2006-04-25 2007-04-24 Composés thérapeutiques

Publications (2)

Publication Number Publication Date
EP2079704A2 EP2079704A2 (fr) 2009-07-22
EP2079704A4 true EP2079704A4 (fr) 2011-11-16

Family

ID=38656126

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07755933A Withdrawn EP2079704A4 (fr) 2006-04-25 2007-04-24 Composés thérapeutiques

Country Status (3)

Country Link
EP (1) EP2079704A4 (fr)
CA (1) CA2665818A1 (fr)
WO (1) WO2007127173A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8093235B2 (en) 2006-04-25 2012-01-10 Rutgers, The State University Of New Jersey Macrocyclic compounds which stabilize G-Quadruplex DNA and RNA
JP2010535204A (ja) 2007-08-02 2010-11-18 ラトガーズ， ザ ステイト ユニバーシティ オブ ニュー ジャージー 治療用化合物
JP5476541B2 (ja) * 2008-06-25 2014-04-23 国立大学法人東京農工大学 テロメラーゼ阻害剤
EP2496704A4 (fr) * 2009-11-05 2013-05-01 Univ Rutgers Composés thérapeutiques
CA2835648A1 (fr) * 2011-05-26 2012-11-29 Novobiotic Pharmaceuticals, Llc Nouveaux antibiotiques

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1602659A1 (fr) * 2003-03-04 2005-12-07 Sosei Co., Ltd. Agent de potentialisation a effet antitumoral contenant du gm-65, preparation antitumorale combinee et agent antitumoral
JP2006316008A (ja) * 2005-05-13 2006-11-24 Soosei:Kk テロメスタチン誘導体

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1602659A1 (fr) * 2003-03-04 2005-12-07 Sosei Co., Ltd. Agent de potentialisation a effet antitumoral contenant du gm-65, preparation antitumorale combinee et agent antitumoral
JP2006316008A (ja) * 2005-05-13 2006-11-24 Soosei:Kk テロメスタチン誘導体

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
A.BERTRAM ET AL, TETRAHEDRON, vol. 59, no. 35, 25 August 2003 (2003-08-25), pages 6979 - 6990, XP004448505, ISSN: 0040-4020, DOI: 10.1016/S0040-4020(03)00821-4 *
A.J. LUCKE ET AL: "Designing supramolecular structures from models of cyclic peptide scaffolds with heterocyclic constraints", JOURNAL OF MOLECULAR GRAPHICS AND MODELLING, no. 21, 2003, pages 341 - 355, XP002659449 *
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002659478, retrieved from STN Database accession no. 2006:1228832 *
G.S. MINHAS ET AL: "Synthesis and G-quadruplex stabilizing properties of a series of oxazole-containing macrocycles", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, no. 15, 1 August 2006 (2006-08-01), pages 3891 - 3895, XP025107094, ISSN: 0960-894X, [retrieved on 20060801], DOI: 10.1016/J.BMCL.2006.05.038 *
S.K. CHATTOPADHYAY ET AL: "Efficient Construction of a Doubly Functionalized Trisoxazole Derivative Relevant to the Synthesis of the Novel Telomerase Inhibitor Telomestatinand its Analogues", SYNTHESIS, no. 8, April 2006 (2006-04-01), pages 1289 - 1294, XP002659448 *
See also references of WO2007127173A2 *
T. DOI ET AL: "Total synthesis of (R)- Telomestatin", ORGANIC LETTERS, vol. 8, no. 18, 2006, pages 4165 - 4167, XP002659451 *
Y. SINGH ET AL: "Novel Cylindrical, Conical, and Macrocyclic Peptides from the Cyclooligomerization of Functionalized Thiazole Amino Acids", J. AM. CHEM. SOC., vol. 123, no. 2, 2001, pages 333 - 334, XP002659450 *
Y. SINGH ET AL: "Supporting information: Novel Cylindrical, Conical, and Macrocyclic Peptides from the Cyclooligomerization of Functionalized Thiazole Amino Acids", J. AM. CHEM. SOC., vol. 123, no. 2, 2001, pages 1 - 13, XP002660487 *

Also Published As

Publication number Publication date
WO2007127173A3 (fr) 2008-12-18
WO2007127173A2 (fr) 2007-11-08
WO2007127173A4 (fr) 2009-02-05
CA2665818A1 (fr) 2007-11-08
EP2079704A2 (fr) 2009-07-22

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20090331

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK RS

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 35/00 20060101ALI20110928BHEP

Ipc: A61K 31/424 20060101ALI20110928BHEP

Ipc: C07D 515/22 20060101ALI20110928BHEP

Ipc: C07D 513/22 20060101ALI20110928BHEP

Ipc: C07D 498/22 20060101AFI20110928BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20111018

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 35/00 20060101ALI20111011BHEP

Ipc: A61K 31/424 20060101ALI20111011BHEP

Ipc: C07D 515/22 20060101ALI20111011BHEP

Ipc: C07D 513/22 20060101ALI20111011BHEP

Ipc: C07D 498/22 20060101AFI20111011BHEP

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: UNIVERSITY OF MEDECINE AND DENTISTRY OF NEW JERSEY

Owner name: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

17Q First examination report despatched

Effective date: 20140714

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20141101