EP2267155A3 - Procédé de détection de mRNA du papillomavirus - Google Patents

Procédé de détection de mRNA du papillomavirus Download PDF

Info

Publication number
EP2267155A3
EP2267155A3 EP10184669A EP10184669A EP2267155A3 EP 2267155 A3 EP2267155 A3 EP 2267155A3 EP 10184669 A EP10184669 A EP 10184669A EP 10184669 A EP10184669 A EP 10184669A EP 2267155 A3 EP2267155 A3 EP 2267155A3
Authority
EP
European Patent Office
Prior art keywords
human papillomavirus
mrna
expression
detecting human
screening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10184669A
Other languages
German (de)
English (en)
Other versions
EP2267155A2 (fr
EP2267155B1 (fr
EP2267155B2 (fr
Inventor
Frank Karlsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norchip AS
Original Assignee
Norchip AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26246916&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP2267155(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0200239A external-priority patent/GB0200239D0/en
Priority claimed from GB0214124A external-priority patent/GB0214124D0/en
Application filed by Norchip AS filed Critical Norchip AS
Publication of EP2267155A2 publication Critical patent/EP2267155A2/fr
Publication of EP2267155A3 publication Critical patent/EP2267155A3/fr
Publication of EP2267155B1 publication Critical patent/EP2267155B1/fr
Application granted granted Critical
Publication of EP2267155B2 publication Critical patent/EP2267155B2/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/708Specific hybridization probes for papilloma
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP10184669.9A 2002-01-07 2003-01-07 Procédé de détection de mRNA du papillomavirus Expired - Lifetime EP2267155B2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0200239A GB0200239D0 (en) 2002-01-07 2002-01-07 Method for detecting human papillomavirus mRNA
GB0214124A GB0214124D0 (en) 2002-06-19 2002-06-19 Method for detecting human papillomavirus mRNA
EP06075498.3A EP1715062B1 (fr) 2002-01-07 2003-01-07 Procédé de détection de mRNA du papillomavirus
EP03700338A EP1463839B1 (fr) 2002-01-07 2003-01-07 Methode permettant de detecter l'arn messager du papillomavirus humain

Related Parent Applications (5)

Application Number Title Priority Date Filing Date
EP03700338A Division EP1463839B1 (fr) 2002-01-07 2003-01-07 Methode permettant de detecter l'arn messager du papillomavirus humain
EP03700338.1 Division 2003-01-07
EP06075498.3A Division EP1715062B1 (fr) 2002-01-07 2003-01-07 Procédé de détection de mRNA du papillomavirus
EP06075498.3A Division-Into EP1715062B1 (fr) 2002-01-07 2003-01-07 Procédé de détection de mRNA du papillomavirus
EP06075498.3 Division 2006-03-03

Publications (4)

Publication Number Publication Date
EP2267155A2 EP2267155A2 (fr) 2010-12-29
EP2267155A3 true EP2267155A3 (fr) 2011-06-08
EP2267155B1 EP2267155B1 (fr) 2013-03-13
EP2267155B2 EP2267155B2 (fr) 2016-09-07

Family

ID=26246916

Family Applications (5)

Application Number Title Priority Date Filing Date
EP10184669.9A Expired - Lifetime EP2267155B2 (fr) 2002-01-07 2003-01-07 Procédé de détection de mRNA du papillomavirus
EP03700338A Expired - Lifetime EP1463839B1 (fr) 2002-01-07 2003-01-07 Methode permettant de detecter l'arn messager du papillomavirus humain
EP06075498.3A Expired - Lifetime EP1715062B1 (fr) 2002-01-07 2003-01-07 Procédé de détection de mRNA du papillomavirus
EP10184464A Withdrawn EP2272988A3 (fr) 2002-01-07 2003-01-07 Procédé de détection de mRNA du papillomavirus
EP15158266.5A Expired - Lifetime EP2913407B1 (fr) 2002-01-07 2003-01-07 Procédé pour détecter l'arnm du papillomavirus humain

Family Applications After (4)

Application Number Title Priority Date Filing Date
EP03700338A Expired - Lifetime EP1463839B1 (fr) 2002-01-07 2003-01-07 Methode permettant de detecter l'arn messager du papillomavirus humain
EP06075498.3A Expired - Lifetime EP1715062B1 (fr) 2002-01-07 2003-01-07 Procédé de détection de mRNA du papillomavirus
EP10184464A Withdrawn EP2272988A3 (fr) 2002-01-07 2003-01-07 Procédé de détection de mRNA du papillomavirus
EP15158266.5A Expired - Lifetime EP2913407B1 (fr) 2002-01-07 2003-01-07 Procédé pour détecter l'arnm du papillomavirus humain

Country Status (20)

Country Link
US (4) US7553623B2 (fr)
EP (5) EP2267155B2 (fr)
JP (2) JP4558322B2 (fr)
CN (1) CN100422342C (fr)
AT (1) ATE354677T1 (fr)
AU (2) AU2003201639C1 (fr)
BR (1) BR0306723A (fr)
CA (1) CA2472026A1 (fr)
CY (1) CY1106621T1 (fr)
DE (1) DE60311961T2 (fr)
DK (2) DK2913407T3 (fr)
EA (1) EA006975B1 (fr)
ES (2) ES2654909T3 (fr)
IL (2) IL162722A0 (fr)
MX (1) MXPA04006440A (fr)
NO (1) NO20042769L (fr)
NZ (1) NZ533703A (fr)
PT (1) PT1463839E (fr)
SI (1) SI1463839T1 (fr)
WO (1) WO2003057914A2 (fr)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601497B2 (en) 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
US7439016B1 (en) * 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
US20110111389A1 (en) * 2001-11-07 2011-05-12 Diagcor Bioscience Incorporation Limited Rapid genotyping analysis for human papillomavirus and the device thereof
EP2267155B2 (fr) 2002-01-07 2016-09-07 Norchip A/S Procédé de détection de mRNA du papillomavirus
EP1369694A1 (fr) * 2002-04-09 2003-12-10 MTM Laboratories AG Procédé de discrimination entre des métaplasies et des lésions néoplastiques ou préneoplastiques
US7741031B2 (en) * 2003-03-07 2010-06-22 The Public Health Research Institute Of The City Of New York Optically decodable microcarries, arrays and methods
US7361460B2 (en) * 2003-04-11 2008-04-22 Digene Corporation Approach to molecular diagnosis of human papillomavirus-related diseases
EP1510820B1 (fr) * 2003-08-25 2010-03-17 MTM Laboratories AG Procédé pour la détection d'états médicalement pertinents dans des échantillons LBC solubilisés
ATE289685T1 (de) * 2003-08-25 2005-03-15 Mtm Lab Ag Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben
EP1664348B8 (fr) * 2003-09-25 2019-06-12 Third Wave Technologies, Inc. Detection de papillomavirus
WO2005033333A2 (fr) 2003-10-07 2005-04-14 Dako Denmark A/S Methodes et compositions pour le diagnostic de cancer
WO2005062940A2 (fr) 2003-12-22 2005-07-14 John Wayne Cancer Institute Procede et dispositif permettant de prelever et de surveiller in vivo la circulation de composants biologiques
GB0404315D0 (en) * 2004-02-26 2004-03-31 Norchip As Improved detection of human papillomavirus
ITMO20040126A1 (it) 2004-05-21 2004-08-21 Bioanalisi Ct Sud S N C Di Per Sistema per la ricerca ed identificazione di agenti patogeni
WO2006137939A2 (fr) 2004-11-09 2006-12-28 Gen-Probe Incorporated Compositions et methode de detection de streptocoques du groupe a
EP1819835B1 (fr) 2004-12-08 2010-08-04 Gen-Probe Incorporated Detection d'acides nucleiques de types multiples de papillomavirus humains
DK2500439T4 (da) 2005-06-20 2017-11-13 Advanced Cell Diagnostics Inc Kits og produkter til detektering af nukleinsyrer i individuelle celler og til identifikation af sjældne celler fra store heterogene cellepopulationer
EP1844164B1 (fr) * 2005-11-15 2010-07-14 Genoid KFT Procede pour la detection de pathogenes base sur des balises moleculaires
WO2007115582A1 (fr) 2006-04-11 2007-10-18 Bio-Rad Pasteur Détection de hpv et quantification par amplification multiplex en temps réel
US7833716B2 (en) * 2006-06-06 2010-11-16 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
US20100285443A1 (en) * 2006-12-15 2010-11-11 Oncomethylome Sciences Sa Diagnostic Methods for Diseases Caused by a HPV Infection Comprising Determining the Methylation Status of the HPV Genome
EP3095873B1 (fr) 2006-12-21 2018-04-18 Gen-Probe Incorporated Procédés et compositions pour l'amplification d'acide nucléiques
US7838215B2 (en) * 2007-09-25 2010-11-23 Canvir, Inc. Advanced cervical cell screening methods
US9435001B2 (en) 2007-11-01 2016-09-06 Self-Screen B.V. Detection method for cervical HPVS
JP5299986B2 (ja) * 2007-11-01 2013-09-25 国立大学法人山口大学 核酸の定量方法
CA2726396C (fr) * 2008-04-17 2019-03-19 Qiagen Gaithersburg, Inc. Compositions, procede et trousses utilisant des sondes synthetiques pour determiner la presence d'un acide nucleique voulu
US9090948B2 (en) * 2008-09-30 2015-07-28 Abbott Molecular Inc. Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples
TWI419974B (zh) 2008-10-27 2013-12-21 Qiagen Gaithersburg Inc 於自動平台上之快速結果雜交捕捉法
EP2184368A1 (fr) 2008-11-07 2010-05-12 DKFZ Deutsches Krebsforschungszentrum Transcription de diagnostic et motifs d'épissage du HPV16 dans différentes lésions cervicales
WO2010127228A1 (fr) * 2009-05-01 2010-11-04 Qiagen Gaithersburg, Inc. Procédé d'amplification non ciblée pour la détection de formes d'épissage d'arn dans un échantillon
JP5826752B2 (ja) * 2009-09-14 2015-12-02 キアジェン ゲイサーズバーグ インコーポレイテッド 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法
AU2011203450B2 (en) * 2010-01-04 2016-01-07 Qiagen Gaithersburg, Inc. Methods, compositions, and kits for recovery of nucleic acids or proteins from fixed tissue samples
JP2013517803A (ja) 2010-01-29 2013-05-20 キアジェン ゲイサーズバーグ インコーポレイテッド サンプル中のhpvの存在を決定および確認する方法
CA2787924A1 (fr) * 2010-01-29 2011-08-04 Qiagen Gaithersburg, Inc. Procedes et compositions pour la purification et l'analyse multiplexee d'acides nucleiques sequence-specifique
US20110275698A1 (en) * 2010-05-10 2011-11-10 Norchip A/S "test and treat" strategy for treating transforming hpv infection
EP2572001A2 (fr) 2010-05-19 2013-03-27 QIAGEN Gaithersburg, Inc. Procédés et compositions pour purification séquence-spécifique et analyse multiplex d'acides nucléiques
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー. 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ
US8658361B2 (en) 2010-10-21 2014-02-25 Advanced Cell Diagnostics, Inc. Ultra sensitive method for in situ detection of nucleic acids
BR112013017489B1 (pt) * 2011-01-07 2021-06-08 Qiagen Gaithersburg, Inc "métodos para genotipagem de hpv de alto risco e para distinguir entre infecções por hpv 16, hpv 18 e hpv 45".
EP2668290B1 (fr) * 2011-01-28 2017-05-31 Advanced Cell Diagnostics, Inc. Dosage pvh rnascope® pour la détermination du statut pvh dans les cancers de la tête et du cou et les lésions cervicales
WO2012116220A2 (fr) 2011-02-24 2012-08-30 Qiagen Gaithersburg, Inc. Matériels et procédés de détection d'acide nucléique de hpv
US20130095474A1 (en) * 2011-10-13 2013-04-18 Joseph Mamone Design of stem-loop probes and utilization in snp genotyping
ES2730711T3 (es) 2011-11-03 2019-11-12 Qiagen Gaithersburg Inc Materiales y métodos para inmovilizar, aislar y concentrar células usando superficies carboxiladas
CN102864224A (zh) * 2012-09-11 2013-01-09 南京大学 一种血清microRNAs试剂盒及其应用
GB201310933D0 (en) 2013-06-19 2013-07-31 Norchip As A method of cervical screening
CA2932859A1 (fr) * 2013-12-05 2015-06-11 Optipharm. Co., Ltd. Procede de diagnostic ameliore du cancer du col de l'uterus et kit de diagnostic associe
WO2016005789A1 (fr) * 2014-07-07 2016-01-14 Institut Pasteur Transcriptome de papillomavirus à large spectre génétique et génotypique en tant que biomarqueur de stades du cancer associé à papillomavirus
CN106048014B (zh) * 2016-06-07 2019-12-10 博奥生物集团有限公司 一种用于实时检测nasba产物的高特异探针
US20190112673A1 (en) * 2017-05-10 2019-04-18 Genomic Vision Association between integration of high-risk hpv genomes detected by molecular combing and the severity and/or clinical outcome of cervical lesions
JP6831772B2 (ja) 2017-12-22 2021-02-17 株式会社Subaru 画像投影装置
CN114214343A (zh) * 2021-11-15 2022-03-22 上海市东方医院(同济大学附属东方医院) 一组高危型HPV整合所致的宫颈癌中特异表达的mRNA序列

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026934A2 (fr) * 1993-05-06 1994-11-24 Baxter Diagnostics Inc. Methode de detection du papillomavirus chez l'homme
EP0662518A2 (fr) * 1989-12-01 1995-07-12 Amoco Corporation Sonde d'acide nucléique pour détection des transcriptions du VPH
DE4431174A1 (de) * 1994-09-01 1996-03-07 Deutsches Krebsforsch Nachweisverfahren für tumorspezifische mRNA
WO1999029890A2 (fr) * 1997-12-12 1999-06-17 Digene Corporation Evaluation de maladies liees au virus du papillome humain

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE76429T1 (de) 1986-03-21 1992-06-15 Pasteur Institut Bestimmte, von einem papillomavirus-genom abgeleitete dns-sequenzen, deren anwendungen fuer in vitro-diagnostische zwecke und die herstellung von antigenzusammensetzungen.
EP0357611B1 (fr) * 1987-02-26 1995-04-26 The University Of Sydney Procede de detection de papillomavirus humains carcinogenes
US5182377A (en) 1988-09-09 1993-01-26 Hoffmann-La Roche Inc. Probes for detection of human papillomavirus
US5639871A (en) * 1988-09-09 1997-06-17 Roche Molecular Systems, Inc. Detection of human papillomavirus by the polymerase chain reaction
DE3838269A1 (de) * 1988-11-11 1990-05-17 Behringwerke Ag Nachweis humaner papillomavirus dna und ihrer expression in zervix-abstrichen
NL8900725A (nl) 1989-03-23 1990-10-16 Az Univ Amsterdam Werkwijze en combinatie van middelen voor het isoleren van nucleinezuur.
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
JP2791685B2 (ja) 1989-06-08 1998-08-27 寳酒造株式会社 パピローマウイルスの検出方法
US5580970A (en) * 1989-12-01 1996-12-03 Amoco Corporation Detection of HPV transcripts
NL9000134A (nl) 1990-01-19 1991-08-16 Stichting Res Fonds Pathologie Primers en werkwijze voor het detecteren van humaan papilloma virus genotypen m.b.v. pcr.
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US5474796A (en) 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5506105A (en) * 1991-12-10 1996-04-09 Dade International Inc. In situ assay of amplified intracellular mRNA targets
US6174668B1 (en) * 1993-05-14 2001-01-16 Johnson & Johnson Clinical Diagnostics, Inc. Diagnostic compositions, elements, methods and test kits for amplification and detection of two or more target DNA's using primers having matched melting temperatures
DK1921169T3 (da) 1993-11-12 2012-06-04 Phri Properties Inc Hybridiseringssonder til nukleinsyredetektion, universelle stamceller, fremgangsmåder og kits
DE19506561C1 (de) * 1995-02-24 1996-10-10 Deutsches Krebsforsch Verfahren zur Früherkennung von HPV-assoziierten Karzinomen bzw. von hochgradigen, durch HPV-verursachten Dysplasien
AU726047B2 (en) 1995-11-15 2000-10-26 Gen-Probe Incorporated Nucleic acid probes complementary to human papillomavirus nucleic acid and related methods and kits
US6027981A (en) 1997-10-27 2000-02-22 Texas Instruments - Acer Incorporated Method for forming a DRAM cell with a fork-shaped capacitor
AU4515699A (en) 1998-06-26 2000-01-17 Akzo Nobel N.V. Tagging of rna amplicons generated by transcription-based amplification
AU2001249526A1 (en) 2000-03-28 2001-10-08 Biosearch International Pty Ltd Approaches for hpv detection and staging by targeting the e6 gene region of the viral genome
US7439016B1 (en) * 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
GB0018050D0 (en) * 2000-07-21 2000-09-13 Norchip As Detection of human papillomavirus mRNA
ES2276948T3 (es) * 2001-08-23 2007-07-01 MERCK & CO., INC. Ensayos pcr de hp multiplex fluorescente que usan fluoforos multiples.
GB0200258D0 (en) * 2002-01-07 2002-02-20 Norchip As Detection of human papillomavirus
EP2267155B2 (fr) * 2002-01-07 2016-09-07 Norchip A/S Procédé de détection de mRNA du papillomavirus
GB0404315D0 (en) 2004-02-26 2004-03-31 Norchip As Improved detection of human papillomavirus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0662518A2 (fr) * 1989-12-01 1995-07-12 Amoco Corporation Sonde d'acide nucléique pour détection des transcriptions du VPH
WO1994026934A2 (fr) * 1993-05-06 1994-11-24 Baxter Diagnostics Inc. Methode de detection du papillomavirus chez l'homme
DE4431174A1 (de) * 1994-09-01 1996-03-07 Deutsches Krebsforsch Nachweisverfahren für tumorspezifische mRNA
WO1999029890A2 (fr) * 1997-12-12 1999-06-17 Digene Corporation Evaluation de maladies liees au virus du papillome humain

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BOSCH F X ET AL: "PREVALENCE OF HUMAN PAPILLOMAVIRUS IN CERVICAL CANCER: A WORLDWIDE PERSPECTIVE", JOURNAL OF THE NATIONAL CANCER INSTITUTE, OXFORD UNIVERSITY PRESS, GB, vol. 87, no. 11, 7 June 1995 (1995-06-07), pages 796 - 802, XP008017322, ISSN: 0027-8874, DOI: 10.1093/JNCI/87.11.796 *
MUÑOZ N: "Human papillomavirus and cancer: the epidemiological evidence.", JOURNAL OF CLINICAL VIROLOGY : THE OFFICIAL PUBLICATION OF THE PAN AMERICAN SOCIETY FOR CLINICAL VIROLOGY OCT 2000 LNKD- PUBMED:11091143, vol. 19, no. 1-2, October 2000 (2000-10-01), pages 1 - 5, XP002633297, ISSN: 1386-6532 *
SCHNEIDER A., HOYER H., DÜRST M.: "Bedeutung des Nachweises von humanen Papillomviren für die Vorsorge", DEUTSCHES ÄRTZEBLATT, vol. 98, no. 39, 28 September 2001 (2001-09-28), pages A2517 - A2521, XP002633298 *
SMITS H L ET AL: "APPLICATION OF THE NASBA NUCLEIC ACID AMPLIFICATION METHOD FOR THE DETECTION OF HUMAN PAPILLOMAVIRUS TYPE 16 E6-E7 TRANSCRIPTS", JOURNAL OF VIROLOGICAL METHODS, AMSTERDAM, NL, vol. 54, no. 1, 1995, pages 75 - 81, XP009015131, ISSN: 0166-0934 *

Also Published As

Publication number Publication date
CN100422342C (zh) 2008-10-01
IL162722A (en) 2013-09-30
US7553623B2 (en) 2009-06-30
US20090275044A1 (en) 2009-11-05
DE60311961D1 (de) 2007-04-05
US20050118568A1 (en) 2005-06-02
EP2913407B1 (fr) 2017-11-01
ES2654909T3 (es) 2018-02-15
JP5204132B2 (ja) 2013-06-05
JP4558322B2 (ja) 2010-10-06
EA200400919A1 (ru) 2005-02-24
EP1715062A2 (fr) 2006-10-25
WO2003057914A3 (fr) 2004-02-26
EP2267155A2 (fr) 2010-12-29
WO2003057914A2 (fr) 2003-07-17
CY1106621T1 (el) 2012-01-25
AU2003201639C1 (en) 2009-02-26
CN1639357A (zh) 2005-07-13
ES2282599T3 (es) 2007-10-16
EA006975B1 (ru) 2006-06-30
AU2003201639A1 (en) 2003-07-24
DK2913407T3 (en) 2018-01-15
SI1463839T1 (sl) 2007-08-31
JP2005514038A (ja) 2005-05-19
EP2267155B1 (fr) 2013-03-13
DK1463839T3 (da) 2007-07-02
EP1715062A3 (fr) 2007-07-11
EP2267155B2 (fr) 2016-09-07
NZ533703A (en) 2006-05-26
EP2272988A2 (fr) 2011-01-12
JP2010131020A (ja) 2010-06-17
BR0306723A (pt) 2004-12-21
ATE354677T1 (de) 2007-03-15
EP2913407A1 (fr) 2015-09-02
US7812144B2 (en) 2010-10-12
US20130309658A1 (en) 2013-11-21
EP1715062B1 (fr) 2015-03-11
CA2472026A1 (fr) 2003-07-17
NO20042769L (no) 2004-10-04
EP1463839A2 (fr) 2004-10-06
DE60311961T2 (de) 2007-10-18
MXPA04006440A (es) 2005-03-31
EP1463839B1 (fr) 2007-02-21
IL162722A0 (en) 2005-11-20
US20090253124A1 (en) 2009-10-08
US8420314B2 (en) 2013-04-16
EP2272988A3 (fr) 2011-06-15
AU2008205436A1 (en) 2008-09-04
HK1065827A1 (en) 2005-03-04
PT1463839E (pt) 2007-05-31
AU2003201639B2 (en) 2008-05-15

Similar Documents

Publication Publication Date Title
EP2267155A3 (fr) Procédé de détection de mRNA du papillomavirus
WO2004079014A3 (fr) Signatures de statut er d'un cancer du sein
WO2006075245A3 (fr) Systemes, methodes et compositions pour la detection de papillomavirus humain dans des echantillons biologiques
WO2004103007A3 (fr) Appareil et procede permettant de fournir des informations de localisation
AU2003288556A1 (en) Scoring estrogen and progesterone receptors expression based on image analysis
WO2005098037A8 (fr) Signatures du cancer du sein
WO2004045455A3 (fr) Plaques vissées déformables
NZ595356A (en) Methods of predicting cancer risk using gene expression in premalignant tissue
WO2002023483A3 (fr) Technique servant a manipuler des images medicales
WO2006063065A3 (fr) Detection d'acides nucleiques de types multiples de papillomavirus humains
EP1434357A3 (fr) Procédé d'économie d'énergie pour un appareil électronique
EP2249155A3 (fr) Marqueur du cancer
WO2002008460A3 (fr) Procede de detection d'arnm de papillomavirus humain
EP2465525A3 (fr) Cellules NKT élevées et leurs utilisations dans le traitement de troubles liés à l'immunité
AU2003284701A1 (en) Method of examining blood type and apparatus for examining blood type using the method.
WO2003023056A3 (fr) Marqueurs specifiques a la sclerose en plaques
WO2010033619A3 (fr) Systèmes, procédés, et compositions permettant de détecter le virus à papillome humain dans des échantillons biologiques
AU3205600A (en) Method and kit for early cancer prediction
WO2006096224A3 (fr) Procede de detection simultanee d'arn et d'adn de papillomavirus humain dans un echantillon
EP1465058A3 (fr) Procédé et appareil pour la multiplication modulaire
DE602006009117D1 (de) Verfahren zur identifizierung von die stresstoleranz in hefe erhöhenden genen sowie verwendung dieser gene zur verbesserung von hefestämmen
AU2003295246A1 (en) In vitro diagnosis method for early detection of cervical dysplasias and cancer, associated with hpv
AU2003294932A1 (en) Method for the detection of cancer
WO2003020976A3 (fr) Oligonucleotides destines a etre utilises dans la detection du papillomavirus humain e7 mrna
Daimoto et al. Simultaneous measuring of eye fixation related potentials (lambda response) and auditory P300 on multiple tracking task

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AC Divisional application: reference to earlier application

Ref document number: 1715062

Country of ref document: EP

Kind code of ref document: P

Ref document number: 1463839

Country of ref document: EP

Kind code of ref document: P

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO

17P Request for examination filed

Effective date: 20111208

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AC Divisional application: reference to earlier application

Ref document number: 1463839

Country of ref document: EP

Kind code of ref document: P

Ref document number: 1715062

Country of ref document: EP

Kind code of ref document: P

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 600857

Country of ref document: AT

Kind code of ref document: T

Effective date: 20130315

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 60343534

Country of ref document: DE

Effective date: 20130508

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130624

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130613

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 600857

Country of ref document: AT

Kind code of ref document: T

Effective date: 20130313

REG Reference to a national code

Ref country code: NL

Ref legal event code: VDEP

Effective date: 20130313

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130614

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130715

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

PLBI Opposition filed

Free format text: ORIGINAL CODE: 0009260

PLAX Notice of opposition and request to file observation + time limit sent

Free format text: ORIGINAL CODE: EPIDOSNOBS2

26 Opposition filed

Opponent name: BECKMAN COULTER, INC.

Effective date: 20131212

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

REG Reference to a national code

Ref country code: DE

Ref legal event code: R026

Ref document number: 60343534

Country of ref document: DE

Effective date: 20131212

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

PLAF Information modified related to communication of a notice of opposition and request to file observations + time limit

Free format text: ORIGINAL CODE: EPIDOSCOBS2

PLBB Reply of patent proprietor to notice(s) of opposition received

Free format text: ORIGINAL CODE: EPIDOSNOBS3

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140107

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140131

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140131

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140107

PLAB Opposition data, opponent's data or that of the opponent's representative modified

Free format text: ORIGINAL CODE: 0009299OPPO

R26 Opposition filed (corrected)

Opponent name: BECKMAN COULTER, INC.

Effective date: 20131212

APBM Appeal reference recorded

Free format text: ORIGINAL CODE: EPIDOSNREFNO

APBP Date of receipt of notice of appeal recorded

Free format text: ORIGINAL CODE: EPIDOSNNOA2O

APAH Appeal reference modified

Free format text: ORIGINAL CODE: EPIDOSCREFNO

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 14

APBU Appeal procedure closed

Free format text: ORIGINAL CODE: EPIDOSNNOA9O

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20130313

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20030107

PUAH Patent maintained in amended form

Free format text: ORIGINAL CODE: 0009272

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: PATENT MAINTAINED AS AMENDED

27A Patent maintained in amended form

Effective date: 20160907

AK Designated contracting states

Kind code of ref document: B2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

REG Reference to a national code

Ref country code: DE

Ref legal event code: R102

Ref document number: 60343534

Country of ref document: DE

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 15

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 16

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20220118

Year of fee payment: 20

Ref country code: DE

Payment date: 20220124

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20220114

Year of fee payment: 20

REG Reference to a national code

Ref country code: DE

Ref legal event code: R071

Ref document number: 60343534

Country of ref document: DE

REG Reference to a national code

Ref country code: GB

Ref legal event code: PE20

Expiry date: 20230106

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20230106