EP2353005A4 - Verfahren und zusammensetzungen zur erkennung komplementbindender antikörper - Google Patents

Verfahren und zusammensetzungen zur erkennung komplementbindender antikörper

Info

Publication number
EP2353005A4
EP2353005A4 EP09830911A EP09830911A EP2353005A4 EP 2353005 A4 EP2353005 A4 EP 2353005A4 EP 09830911 A EP09830911 A EP 09830911A EP 09830911 A EP09830911 A EP 09830911A EP 2353005 A4 EP2353005 A4 EP 2353005A4
Authority
EP
European Patent Office
Prior art keywords
compositions
detection
methods
complement fixing
fixing antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP09830911A
Other languages
English (en)
French (fr)
Other versions
EP2353005B1 (de
EP2353005A1 (de
Inventor
Dolly B Tyan
Ge Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Priority to EP18190547.2A priority Critical patent/EP3460480B1/de
Publication of EP2353005A1 publication Critical patent/EP2353005A1/de
Publication of EP2353005A4 publication Critical patent/EP2353005A4/de
Application granted granted Critical
Publication of EP2353005B1 publication Critical patent/EP2353005B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP09830911.5A 2008-12-01 2009-11-25 Verfahren und zusammensetzungen zur erkennung komplementbindender antikörper Active EP2353005B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP18190547.2A EP3460480B1 (de) 2008-12-01 2009-11-25 Verfahren und zusammensetzungen zur bestimmung von komplement-fixierendern antikörpern

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11894908P 2008-12-01 2008-12-01
PCT/US2009/065984 WO2010065425A1 (en) 2008-12-01 2009-11-25 Methods and compositions for detection of complement fixing antibodies

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP18190547.2A Division EP3460480B1 (de) 2008-12-01 2009-11-25 Verfahren und zusammensetzungen zur bestimmung von komplement-fixierendern antikörpern
EP18190547.2A Division-Into EP3460480B1 (de) 2008-12-01 2009-11-25 Verfahren und zusammensetzungen zur bestimmung von komplement-fixierendern antikörpern

Publications (3)

Publication Number Publication Date
EP2353005A1 EP2353005A1 (de) 2011-08-10
EP2353005A4 true EP2353005A4 (de) 2012-10-17
EP2353005B1 EP2353005B1 (de) 2018-10-03

Family

ID=42233567

Family Applications (2)

Application Number Title Priority Date Filing Date
EP18190547.2A Active EP3460480B1 (de) 2008-12-01 2009-11-25 Verfahren und zusammensetzungen zur bestimmung von komplement-fixierendern antikörpern
EP09830911.5A Active EP2353005B1 (de) 2008-12-01 2009-11-25 Verfahren und zusammensetzungen zur erkennung komplementbindender antikörper

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP18190547.2A Active EP3460480B1 (de) 2008-12-01 2009-11-25 Verfahren und zusammensetzungen zur bestimmung von komplement-fixierendern antikörpern

Country Status (8)

Country Link
US (1) US10338080B2 (de)
EP (2) EP3460480B1 (de)
JP (2) JP5792626B2 (de)
CN (2) CN105866426B (de)
AU (1) AU2009322607B2 (de)
BR (1) BRPI0923199B8 (de)
CA (1) CA2740192C (de)
WO (1) WO2010065425A1 (de)

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JP6538561B2 (ja) 2012-10-25 2019-07-03 バイオベラティブ・ユーエスエイ・インコーポレイテッド 抗補体Ｃ１ｓ抗体とそれらの用途
CN116063483A (zh) 2012-11-02 2023-05-05 美国比奥维拉迪维股份有限公司 抗补体C1s抗体和其用途
WO2014160376A1 (en) * 2013-03-14 2014-10-02 The Board Of Trustees Of The Leland Stanford Junior University Methods of detecting complement fixing and non-complement fixing antibodies and systems for practicing the same
CA2905954C (en) * 2013-03-14 2022-03-22 The Board Of Trustees Of The Leland Stanford Junior University Methods of detecting donor-specific antibodies and systems for practicing the same
SG10202008809RA (en) 2013-07-09 2020-10-29 Annexon Inc Anti-complement factor c1q antibodies and uses thereof
SG10202008810QA (en) * 2014-11-05 2020-10-29 Annexon Inc Humanized anti-complement factor c1q antibodies and uses thereof
IL318523A (en) 2015-04-06 2025-03-01 Bioverativ Usa Inc Human anti-C1S antibodies and methods of using them
US10527613B2 (en) 2015-11-10 2020-01-07 The Board Of Trustees Of The Leland Stanford Junior University Biomarker detection methods and systems and kits for practicing same
BR112018010360A2 (en) 2015-11-24 2018-12-04 Annexon, Inc. anti-c1q complement factor fab fragments and uses thereof
AU2016364990B9 (en) 2015-12-03 2021-06-24 NJ Sharing Network IgG subtyping assay for identifying transplantable tissue samples
EP3239711B1 (de) * 2016-04-27 2019-12-25 JIMRO Co., Ltd. Verfahren zur messung von anti-wirkstoff-antikörpern
WO2017187656A1 (ja) * 2016-04-27 2017-11-02 株式会社Jimro 抗医薬品抗体の測定方法
JP7069138B2 (ja) 2016-10-12 2022-05-17 バイオベラティブ・ユーエスエイ・インコーポレイテッド 抗Ｃ１ｓ抗体およびその使用方法
WO2018140655A2 (en) * 2017-01-25 2018-08-02 Northeastern University Electrochemical antibody-based biosensor
CN114910634B (zh) * 2017-10-26 2025-05-23 科美诊断技术股份有限公司 一种无基质效应的均相免疫检测试剂盒及其分析方法和应用
CN107976535B (zh) * 2017-11-03 2020-03-20 科美诊断技术股份有限公司 一种检测样本中目标IgM抗体的均相免疫检测试剂盒及其使用方法和应用
CN109991405B (zh) * 2017-12-29 2023-01-24 上海索昕生物科技有限公司 一种免疫检测试剂盒及其应用
JP7153494B2 (ja) * 2018-07-27 2022-10-14 シスメックス株式会社 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット
JP7153493B2 (ja) * 2018-07-27 2022-10-14 シスメックス株式会社 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット
CA3136684A1 (en) * 2019-05-06 2020-11-12 The Regents Of The University Of California Non-hla markers of transplant rejection
CN111812336A (zh) * 2020-08-10 2020-10-23 苏州康和顺医疗技术有限公司 用于检测冠状病毒抗体的检测试剂盒及其制备方法
EP4226155A1 (de) * 2020-10-09 2023-08-16 Takeda Vaccines, Inc. Verfahren zur bestimmung komplementfixierender antikörper
WO2022212704A1 (en) * 2021-03-31 2022-10-06 Takeda Vaccines, Inc. Methods for characterizing the immune response of a subject to a dengue virus composition
EP4089413A1 (de) * 2021-05-12 2022-11-16 Cisbio Bioassays Verfahren zur bestimmung der bindung eines antikörpers an die komplement-komponente 1q (c1q)
WO2023114763A1 (en) 2021-12-13 2023-06-22 Annexon, Inc. Anti-complement factor c1q antibodies with single binding arms and uses thereof
CN118604345A (zh) * 2024-05-31 2024-09-06 上海览屹医药科技有限公司 酶联免疫方法测定单克隆抗体浓度
CN120142127A (zh) * 2025-05-16 2025-06-13 上海荻硕贝肯基因科技有限公司 一种供者特异性抗体的检测方法

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US5035995A (en) * 1984-10-02 1991-07-30 Calpis Food Industry Co., Ltd. Test method involving substance-conjugated complement component C1q
US5270169A (en) * 1992-06-23 1993-12-14 Sangstat Medical Corporation Detection of HLA antigen-containing immune complexes

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Also Published As

Publication number Publication date
EP3460480A1 (de) 2019-03-27
AU2009322607A1 (en) 2010-06-10
CN105866426B (zh) 2018-11-23
JP5792626B2 (ja) 2015-10-14
JP2015007651A (ja) 2015-01-15
JP2012510618A (ja) 2012-05-10
EP2353005B1 (de) 2018-10-03
US10338080B2 (en) 2019-07-02
EP3460480B1 (de) 2022-11-02
AU2009322607B2 (en) 2015-05-14
WO2010065425A1 (en) 2010-06-10
CA2740192A1 (en) 2010-06-10
BRPI0923199B1 (pt) 2020-10-20
CN105866426A (zh) 2016-08-17
US20110281757A1 (en) 2011-11-17
EP2353005A1 (de) 2011-08-10
CA2740192C (en) 2019-12-31
CN102203610A (zh) 2011-09-28
BRPI0923199B8 (pt) 2021-07-27
BRPI0923199A2 (pt) 2016-02-16

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