EP2620767A4 - Analyseur de cellules - Google Patents

Analyseur de cellules Download PDF

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Publication number
EP2620767A4
EP2620767A4 EP11826549.5A EP11826549A EP2620767A4 EP 2620767 A4 EP2620767 A4 EP 2620767A4 EP 11826549 A EP11826549 A EP 11826549A EP 2620767 A4 EP2620767 A4 EP 2620767A4
Authority
EP
European Patent Office
Prior art keywords
cell analyzer
analyzer
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP11826549.5A
Other languages
German (de)
English (en)
Other versions
EP2620767B1 (fr
EP2620767A1 (fr
Inventor
Toshihiro Ootani
Ryuichiro Ebi
Koki Tajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sysmex Corp
Original Assignee
Sysmex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Publication of EP2620767A1 publication Critical patent/EP2620767A1/fr
Publication of EP2620767A4 publication Critical patent/EP2620767A4/fr
Application granted granted Critical
Publication of EP2620767B1 publication Critical patent/EP2620767B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4704—Angular selective
    • G01N2021/4707—Forward scatter; Low angle scatter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4704—Angular selective
    • G01N2021/4726—Detecting scatter at 90°
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer
    • G01N2035/00554—Mixing by a special element, e.g. stirrer using ultrasound
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP11826549.5A 2010-09-22 2011-08-31 Analyseur de cellules Active EP2620767B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010212613A JP5784294B2 (ja) 2010-09-22 2010-09-22 細胞分析装置および細胞分析方法
PCT/JP2011/004868 WO2012039097A1 (fr) 2010-09-22 2011-08-31 Analyseur de cellules

Publications (3)

Publication Number Publication Date
EP2620767A1 EP2620767A1 (fr) 2013-07-31
EP2620767A4 true EP2620767A4 (fr) 2018-01-17
EP2620767B1 EP2620767B1 (fr) 2021-10-20

Family

ID=45873602

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11826549.5A Active EP2620767B1 (fr) 2010-09-22 2011-08-31 Analyseur de cellules

Country Status (5)

Country Link
US (1) US8921099B2 (fr)
EP (1) EP2620767B1 (fr)
JP (1) JP5784294B2 (fr)
CN (1) CN103109184B (fr)
WO (1) WO2012039097A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014209090A (ja) 2013-03-29 2014-11-06 シスメックス株式会社 細胞分析方法及び装置
JP6378599B2 (ja) 2013-10-11 2018-08-22 シスメックス株式会社 細胞分析方法および細胞分析装置
KR101538096B1 (ko) 2014-07-08 2015-07-21 현대중공업 주식회사 탭 절환기
CN108027280B (zh) 2015-06-26 2021-07-06 雅培实验室 用于使得反应容器在诊断分析仪中从处理轨道运动至旋转装置的反应容器运动部件
JP6139603B2 (ja) * 2015-06-30 2017-05-31 シスメックス株式会社 塗抹標本作製装置、血液検体処理システム、および、塗抹標本作製装置における血液処理部の洗浄方法
CN106596495B (zh) * 2016-12-29 2019-04-02 国家纳米科学中心 一种多通道荧光相关光谱的多聚体检测数据处理方法
WO2019035952A1 (fr) * 2017-08-15 2019-02-21 University Of Washington Systèmes et procédés de séparation de particules
US12332165B2 (en) * 2018-05-16 2025-06-17 President And Fellows Of Harvard College Volatile liquid analysis
JP2022071963A (ja) * 2020-10-29 2022-05-17 シスメックス株式会社 試料調製方法、細胞分析方法、試料調製装置および細胞分析装置
JP2022133676A (ja) * 2021-03-02 2022-09-14 公立大学法人大阪 蛍光ｘ線分析装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020054834A1 (en) * 2000-07-01 2002-05-09 Catterall Olive Patrick Ashley Sample handling system
WO2009123000A1 (fr) * 2008-03-31 2009-10-08 シスメックス株式会社 Dispositif de traitement de cellules, dispositif de préparation d'échantillons et dispositif d'analyse de cellules

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0746101B2 (ja) * 1986-12-30 1995-05-17 素秀 高浜 粘液溶解性を具備した細胞固定・保存液
US5139031A (en) * 1989-09-18 1992-08-18 La Mina Ltd. Method and device for cytology and microbiological testing
JP2966057B2 (ja) * 1990-07-19 1999-10-25 株式会社千代田製作所 自動細胞処理装置
JPH0580053A (ja) 1991-03-22 1993-03-30 Shiro Nozawa ヒト子宮体癌細胞の免疫化学的検出方法
JP4136187B2 (ja) * 1999-05-14 2008-08-20 シスメックス株式会社 検体移し替え装置
EP1057534A1 (fr) * 1999-06-03 2000-12-06 Haemonetics Corporation Bol de centrifugation avec noyau filtrant
US6436704B1 (en) * 2000-04-10 2002-08-20 Raven Biotechnologies, Inc. Human pancreatic epithelial progenitor cells and methods of isolation and use thereof
US6872565B2 (en) * 2003-01-29 2005-03-29 Biogaia Ab Product containing Lactobacillus reuteri strain ATTC PTA-4965 or PTA-4964 for inhibiting bacteria causing dental caries
JP2005315862A (ja) * 2004-03-30 2005-11-10 Sysmex Corp 子宮頸癌のスクリーニング方法及び子宮頸癌診断薬
CN1677109A (zh) * 2004-03-30 2005-10-05 希森美康株式会社 子宫颈癌的筛选方法
WO2006129735A1 (fr) * 2005-05-31 2006-12-07 Olympus Corporation Cellule a gene transfere et procede d’analyse cellulaire
EP1777523A1 (fr) * 2005-10-19 2007-04-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Méthode pour pronostiquer la progression d'un cancer et les résultats du patient et les moyens pour performer la méthode
JP2008249543A (ja) * 2007-03-30 2008-10-16 Tohoku Univ 組織標本からの細胞の調製方法
JP2009192450A (ja) * 2008-02-18 2009-08-27 Public Works Research Institute 植物プランクトンの計測法
CN102057037B (zh) * 2008-04-11 2014-06-18 学校法人庆应义塾 平滑肌干细胞的分离方法
CN102089427B (zh) 2008-07-10 2014-03-12 希森美康株式会社 细胞分散方法、细胞分散剂及细胞测定方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020054834A1 (en) * 2000-07-01 2002-05-09 Catterall Olive Patrick Ashley Sample handling system
WO2009123000A1 (fr) * 2008-03-31 2009-10-08 シスメックス株式会社 Dispositif de traitement de cellules, dispositif de préparation d'échantillons et dispositif d'analyse de cellules

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FOLADORI P ET AL: "Bacteria permeabilisation and disruption caused by sludge reduction technologies evaluated by flow cytometry", WATER RESEARCH, ELSEVIER, AMSTERDAM, NL, vol. 44, no. 17, 16 July 2010 (2010-07-16), pages 4888 - 4899, XP027367880, ISSN: 0043-1354, [retrieved on 20100716] *
See also references of WO2012039097A1 *

Also Published As

Publication number Publication date
US8921099B2 (en) 2014-12-30
WO2012039097A1 (fr) 2012-03-29
EP2620767B1 (fr) 2021-10-20
CN103109184A (zh) 2013-05-15
JP2012068108A (ja) 2012-04-05
EP2620767A1 (fr) 2013-07-31
JP5784294B2 (ja) 2015-09-24
US20130217110A1 (en) 2013-08-22
CN103109184B (zh) 2015-02-04

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