EP2859112A4 - Verfahren zur herstellung von oligosacchariden und oligosaccharidglykosiden durch fermentation - Google Patents

Verfahren zur herstellung von oligosacchariden und oligosaccharidglykosiden durch fermentation

Info

Publication number
EP2859112A4
EP2859112A4 EP13800288.6A EP13800288A EP2859112A4 EP 2859112 A4 EP2859112 A4 EP 2859112A4 EP 13800288 A EP13800288 A EP 13800288A EP 2859112 A4 EP2859112 A4 EP 2859112A4
Authority
EP
European Patent Office
Prior art keywords
fermentation
producing oligosaccharides
oligosaccharide glycosides
glycosides
oligosaccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13800288.6A
Other languages
English (en)
French (fr)
Other versions
EP2859112A1 (de
Inventor
Pauline Peltier-Pain
Gyula Dekany
Remy Dureau
Christian Risinger
Markus Hederos
Elise Champion
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glycom AS
Original Assignee
Glycom AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycom AS filed Critical Glycom AS
Publication of EP2859112A1 publication Critical patent/EP2859112A1/de
Publication of EP2859112A4 publication Critical patent/EP2859112A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/64—Preparation of S-glycosides, e.g. lincomycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP13800288.6A 2012-06-08 2013-06-07 Verfahren zur herstellung von oligosacchariden und oligosaccharidglykosiden durch fermentation Withdrawn EP2859112A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201270313 2012-06-08
DKPA201200395 2012-06-11
DKPA201270332 2012-06-15
DKPA201270656 2012-10-25
PCT/DK2013/050182 WO2013182206A1 (en) 2012-06-08 2013-06-07 Method for producing oligosaccharides and oligosaccharide glycosides by fermentation

Publications (2)

Publication Number Publication Date
EP2859112A1 EP2859112A1 (de) 2015-04-15
EP2859112A4 true EP2859112A4 (de) 2015-10-28

Family

ID=49711430

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13800288.6A Withdrawn EP2859112A4 (de) 2012-06-08 2013-06-07 Verfahren zur herstellung von oligosacchariden und oligosaccharidglykosiden durch fermentation

Country Status (2)

Country Link
EP (1) EP2859112A4 (de)
WO (1) WO2013182206A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111172220B (zh) * 2013-09-06 2023-08-04 格礼卡姆股份公司 寡糖的发酵生产
PL2896628T3 (pl) 2014-01-20 2019-03-29 Jennewein Biotechnologie Gmbh Sposób wydajnego oczyszczania obojętnych oligosacharydów ludzkiego mleka (HMO) z fermentacji mikrobiologicznej
CN103820513A (zh) * 2014-02-27 2014-05-28 中国科学院微生物研究所 合成唾液酸化寡糖及类似物的方法
DK2927316T3 (en) * 2014-03-31 2019-03-04 Jennewein Biotechnologie Gmbh Total fermentation of oligosaccharides
US11926858B2 (en) 2014-06-27 2024-03-12 Glycom A/S Oligosaccharide production
WO2015197082A1 (en) 2014-06-27 2015-12-30 Glycom A/S Oligosaccharide production
KR20170028438A (ko) * 2014-07-14 2017-03-13 바스프 에스이 Ｌｎｔ, ｌｎｎｔ 및 이들의 푸코실화 유도체의 생명공학적 생산
ES3011213T3 (en) 2015-12-18 2025-04-07 Glycom As Fermentative production of oligosaccharides
ES2991621T3 (es) 2016-03-07 2024-12-04 Glycom As Separación de oligosacáridos de caldo de fermentación
US11312741B2 (en) 2016-04-19 2022-04-26 Glycom A/S Separation of oligosaccharides from fermentation broth
EP3456836A1 (de) 2017-09-13 2019-03-20 Glycom A/S Abtrennung von sialylierten oligosacchariden aus der fermentationsbrühe
US11548908B2 (en) 2017-12-29 2023-01-10 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
JP7547345B2 (ja) 2018-12-27 2024-09-09 グリコミメティクス， インコーポレイテッド ガレクチン－３阻害性ｃ－グリコシド
AU2020354581A1 (en) 2019-09-24 2022-03-03 Prolacta Bioscience, Inc. Compositions and methods for treatment of inflammatory and immune diseases
AU2020409590A1 (en) 2019-12-18 2022-05-19 Inbiose N.V. Production of sialylated oligosaccharide in host cells
EP4077699A1 (de) 2019-12-19 2022-10-26 Basf Se Erhöhung der raum-zeit-ausbeute, der kohlenstoffkonversionseffizienz und kohlenstoffsubstratflexibilität bei der herstellung von feinchemikalien
WO2022013143A1 (en) 2020-07-13 2022-01-20 Glycom A/S Oligosaccharide production
CA3188645A1 (en) 2020-08-14 2022-02-17 Prolacta Bioscience, Inc. Human milk oligosaccharide compositions for use with bacteriotherapies
MX2023008227A (es) 2021-01-12 2023-07-20 Prolacta Bioscience Inc Regimenes de tratamiento simbiotico.
DK181061B1 (en) 2021-03-12 2022-10-31 Glycom As Purification of sialooligosaccharides
US12534701B2 (en) 2021-05-17 2026-01-27 Dsm Ip Assets B.V. Microbial strain expressing an invertase/sucrose hydrolase
WO2024130119A2 (en) 2022-12-16 2024-06-20 Prolacta Bioscience, Inc. Synbiotic compositions for short chain fatty acid production

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796082B1 (fr) 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
WO2008002230A1 (en) * 2006-03-04 2008-01-03 Nilsson Kurt G I Production of glycoside oligosaccharides
EP1996602B8 (de) 2006-03-13 2012-03-14 Glycom A/S Neue lactosaminderivate
EP1911850A1 (de) 2006-10-09 2008-04-16 Centre National De La Recherche Scientifique (Cnrs) Verfahren zur Herstellung von 6-thio-sialierten Glykoproteinen und Glycokonjugaten
US8993740B2 (en) 2010-02-19 2015-03-31 Glycom A/S Method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt) containing N-acetyllactosamine
BR112012020791A2 (pt) 2010-02-19 2016-05-03 Glycom As produção de 6'-o-sialillactose e intermediários
KR20140001198A (ko) 2010-07-16 2014-01-06 글리콤 에이/에스 신규 시알로올리고당 유도체들의 합성
US20140057868A1 (en) 2011-02-21 2014-02-27 Glycom A/S Catalytic hydrogenolysis of a composition of a mixture of oligosaccharide precursors and uses thereof
CN103443113A (zh) 2011-03-18 2013-12-11 格力康公司 新型含岩藻糖的糖类衍生物的合成
EP2712362A4 (de) 2011-05-13 2014-12-24 Glycom As Herstellung von lacto-n-tetraose

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO2013182206A1 *

Also Published As

Publication number Publication date
EP2859112A1 (de) 2015-04-15
WO2013182206A1 (en) 2013-12-12

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