EP2859112A4 - Procédé de production d'oligosaccharides et d'oligosaccharide glycosides par fermentation - Google Patents

Procédé de production d'oligosaccharides et d'oligosaccharide glycosides par fermentation

Info

Publication number
EP2859112A4
EP2859112A4 EP13800288.6A EP13800288A EP2859112A4 EP 2859112 A4 EP2859112 A4 EP 2859112A4 EP 13800288 A EP13800288 A EP 13800288A EP 2859112 A4 EP2859112 A4 EP 2859112A4
Authority
EP
European Patent Office
Prior art keywords
fermentation
producing oligosaccharides
oligosaccharide glycosides
glycosides
oligosaccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13800288.6A
Other languages
German (de)
English (en)
Other versions
EP2859112A1 (fr
Inventor
Pauline Peltier-Pain
Gyula Dekany
Remy Dureau
Christian Risinger
Markus Hederos
Elise Champion
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glycom AS
Original Assignee
Glycom AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycom AS filed Critical Glycom AS
Publication of EP2859112A1 publication Critical patent/EP2859112A1/fr
Publication of EP2859112A4 publication Critical patent/EP2859112A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/64—Preparation of S-glycosides, e.g. lincomycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP13800288.6A 2012-06-08 2013-06-07 Procédé de production d'oligosaccharides et d'oligosaccharide glycosides par fermentation Withdrawn EP2859112A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201270313 2012-06-08
DKPA201200395 2012-06-11
DKPA201270332 2012-06-15
DKPA201270656 2012-10-25
PCT/DK2013/050182 WO2013182206A1 (fr) 2012-06-08 2013-06-07 Procédé de production d'oligosaccharides et d'oligosaccharide glycosides par fermentation

Publications (2)

Publication Number Publication Date
EP2859112A1 EP2859112A1 (fr) 2015-04-15
EP2859112A4 true EP2859112A4 (fr) 2015-10-28

Family

ID=49711430

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13800288.6A Withdrawn EP2859112A4 (fr) 2012-06-08 2013-06-07 Procédé de production d'oligosaccharides et d'oligosaccharide glycosides par fermentation

Country Status (2)

Country Link
EP (1) EP2859112A4 (fr)
WO (1) WO2013182206A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3041946T4 (en) * 2013-09-06 2025-11-03 Glycom As Fermentative production of oligosaccharides
EP2896628B1 (fr) 2014-01-20 2018-09-19 Jennewein Biotechnologie GmbH Procédé permettant de purifier efficacement des oligosaccharides du lait humain neutre (HMO) à partir de la fermentation microbienne
CN103820513A (zh) * 2014-02-27 2014-05-28 中国科学院微生物研究所 合成唾液酸化寡糖及类似物的方法
PL2927316T3 (pl) * 2014-03-31 2019-05-31 Jennewein Biotechnologie Gmbh Całkowita fermentacja oligosacharydów
US11926858B2 (en) 2014-06-27 2024-03-12 Glycom A/S Oligosaccharide production
ES3002778T3 (en) 2014-06-27 2025-03-07 Glycom As Oligosaccharide production
AU2015291487A1 (en) 2014-07-14 2017-02-16 Basf Se Biotechnological production of LNT, LNnT and the fucosylated derivatives thereof
ES3011213T3 (en) 2015-12-18 2025-04-07 Glycom As Fermentative production of oligosaccharides
ES2991621T3 (es) 2016-03-07 2024-12-04 Glycom As Separación de oligosacáridos de caldo de fermentación
DK3445770T3 (da) 2016-04-19 2026-02-23 Glycom As Separering af oligosaccharider fra fermenteringssuppe
EP3456836A1 (fr) 2017-09-13 2019-03-20 Glycom A/S Séparation d'oligosaccharides sialylés d'un bouillon de fermentation
KR20200104889A (ko) 2017-12-29 2020-09-04 글리코미메틱스, 인크. E-셀렉틴 및 갈렉틴-3의 이종이기능성 억제제
CA3122321A1 (fr) 2018-12-27 2020-07-02 Glycomimetics, Inc. C-glycosides inhibiteurs de galectine-3
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
JP2022548785A (ja) 2019-09-24 2022-11-21 プロラクタ バイオサイエンス，インコーポレイテッド 炎症性疾患及び免疫疾患の治療のための組成物及び方法
CN114901825A (zh) 2019-12-18 2022-08-12 因比奥斯公司 在宿主细胞中产生唾液酸化寡糖
EP4077699A1 (fr) 2019-12-19 2022-10-26 Basf Se Augmentation du rendement spatio-temporel, de l'efficacité de conversion du carbone et de la flexibilité des substrat carbonés dans la production de produits chimiques fins
WO2022013143A1 (fr) 2020-07-13 2022-01-20 Glycom A/S Production d'oligosaccharide
KR20230088680A (ko) 2020-08-14 2023-06-20 프롤랙타 바이오사이언스, 인코포레이티드 박테리아 요법에 사용하기 위한 인간 모유 올리고당 조성물
CA3204530A1 (fr) 2021-01-12 2022-07-21 Gregory Mckenzie Regimes de traitement symbiotique
DK181061B1 (en) 2021-03-12 2022-10-31 Glycom As Purification of sialooligosaccharides
US20250320535A1 (en) 2021-05-17 2025-10-16 Dsm Ip Assets B.V. Novel technology to enable sucrose utilization in strains for biosynthetic production
WO2024130119A2 (fr) 2022-12-16 2024-06-20 Prolacta Bioscience, Inc. Compositions symbiotiques pour la production d'acides gras à chaîne courte

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796082B1 (fr) 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
WO2008002230A1 (fr) * 2006-03-04 2008-01-03 Nilsson Kurt G I Production d'oligosaccharides de glucoside
WO2007104311A1 (fr) 2006-03-13 2007-09-20 Glycom Aps Nouveaux dérivés de lactosamine
EP1911850A1 (fr) 2006-10-09 2008-04-16 Centre National De La Recherche Scientifique (Cnrs) Procédé de production de glycoprotéines et glycoconjugates 6-thio-sialylées
WO2011100979A1 (fr) 2010-02-19 2011-08-25 Glycom A/S Production de 6'-o-sialyllactose et intermédiaires
EP3241836B1 (fr) 2010-02-19 2024-10-30 Glycom A/S Polymorph d'un tétrasaccharide contenant du n-acétyllactosamine
AU2011278236A1 (en) 2010-07-16 2013-02-07 Glycom A/S Derivatization of oligosaccharides
WO2012113404A1 (fr) 2011-02-21 2012-08-30 Glycom A/S Nouveaux glycosyles phosphites
CN103443113A (zh) 2011-03-18 2013-12-11 格力康公司 新型含岩藻糖的糖类衍生物的合成
WO2012155916A1 (fr) 2011-05-13 2012-11-22 Glycom A/S Fabrication de lacto-n-tétraose

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO2013182206A1 *

Also Published As

Publication number Publication date
WO2013182206A1 (fr) 2013-12-12
EP2859112A1 (fr) 2015-04-15

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