EP4032824B1 - Logement pour un récipient souple - Google Patents

Logement pour un récipient souple Download PDF

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Publication number
EP4032824B1
EP4032824B1 EP22153960.4A EP22153960A EP4032824B1 EP 4032824 B1 EP4032824 B1 EP 4032824B1 EP 22153960 A EP22153960 A EP 22153960A EP 4032824 B1 EP4032824 B1 EP 4032824B1
Authority
EP
European Patent Office
Prior art keywords
housing
foam
container
flexible container
lined
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP22153960.4A
Other languages
German (de)
English (en)
Other versions
EP4032824A1 (fr
EP4032824C0 (fr
Inventor
Thomas Wurm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Single Use Support GmbH
Original Assignee
Single Use Support GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=62839098&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP4032824(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from ATGM50100/2017U external-priority patent/AT15857U1/de
Application filed by Single Use Support GmbH filed Critical Single Use Support GmbH
Priority to EP24212454.3A priority Critical patent/EP4484329A3/fr
Publication of EP4032824A1 publication Critical patent/EP4032824A1/fr
Application granted granted Critical
Publication of EP4032824C0 publication Critical patent/EP4032824C0/fr
Publication of EP4032824B1 publication Critical patent/EP4032824B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • B65D25/10Devices to locate articles in containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1468Containers characterised by specific material properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/16Holders for containers
    • A61J1/165Cooled holders, e.g. for medications, insulin, blood or plasma
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/14Linings or internal coatings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/02Wrapped articles enclosed in rigid or semi-rigid containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/04Articles or materials enclosed in two or more containers disposed one within another
    • B65D77/06Liquids or semi-liquids or other materials or articles enclosed in flexible containers disposed within rigid containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/02Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
    • B65D81/022Containers made of shock-absorbing material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/02Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
    • B65D81/05Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents
    • B65D81/107Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents using blocks of shock-absorbing material
    • B65D81/113Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents using blocks of shock-absorbing material of a shape specially adapted to accommodate contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers

Definitions

  • the present invention relates to a housing for a flexible container for transporting liquids, in particular drugs.
  • liquids in particular drugs.
  • other liquids that occur in the (bio)pharmaceutical production process can also be transported by means of a flexible container in such a housing.
  • Flexible containers that transport medicines in a housing are also known as “single use bags”. This is usually done in a frozen state, with the flexible container being placed in the housing before freezing. The liquid is then frozen by cooling the arrangement.
  • the volume expansion during freezing (about 8%) creates a pressure on the housing and the flexible container that should not be underestimated. This introduces the risk of mechanical damage and, as a result, leaks in the mechanical container.
  • the object of the present invention is to reduce the mechanical stress on the flexible container and the housing during freezing compared to the prior art.
  • this can at least partially compensate for the volume expansion of the container arranged in the housing that occurs during freezing.
  • the housing is essentially cuboid-shaped. This can facilitate easy stacking of the housings.
  • the cover surfaces of the housing are made of steel.
  • the cover surfaces of the housing rest on cooled surfaces, whereby cover surfaces made of steel result in improved heat transfer compared to the prior art.
  • Protection is also sought for an arrangement comprising a housing according to the invention and a flexible container arranged therein and filled with a liquid, in particular a medicament.
  • a housing according to the invention wherein a liquid, in particular a drug, is filled into the flexible container, the filled container is arranged in the housing and the liquid is frozen by cooling the arrangement of housing and container.
  • Liquids that can be transported in the flexible container include protein solutions, end products of purification, antibody solutions and other high-quality intermediate products in the pharmaceutical production cycle, as well as, of course, the drugs themselves.
  • the housing can optionally be lined with foam in such a way that any volume expansion of the container arranged in the housing that occurs during freezing is essentially completely compensated by the foam.
  • the foam exhibits decreasing elasticity as the temperature drops below freezing. It may also be provided that the foam essentially hardens at a temperature between 0° C and -30° C, preferably between -5° C and -25° C and particularly preferably between -10° C and -20° C. These measures can help ensure that the flexible container in the housing lies in a precisely adapted "bed” in the housing. All forces acting on the flexible container and the housing are thus absorbed by larger surfaces. Damage caused by clamping or the like is thus at least reduced, if not completely eliminated.
  • the foam is designed in such a way that the curing process is reversible.
  • the elasticity of the foam is available again and thus offers a certain degree of protection against impacts on the flexible container when it is removed from the housing.
  • the reversible process means that the housing can in principle be reused if desired.
  • the curing of the foam can also be referred to as solidification. This is not the curing that occurs during the production of the foam, but rather the change in the elastic properties under the influence of cold.
  • the housing is lined with the foam in such a way that the container - preferably including any attachments - is completely surrounded by the foam when the container is in the housing. This means that not only the flexible container but also the attachments can be better protected from damage.
  • attachments for such flexible containers often have different shapes, for example because they consist of deformable hoses and the like, a foam block in the housing that can accommodate the attachments (by deformation) can be advantageous.
  • the flexible container 2 is arranged inside the housing 1.
  • the housing 1 is lined with foam 3 and a foam block 5. If the liquid inside the container 2 freezes, the container 2 expands. This volume expansion is absorbed by the foam 3 and the foam block 5, so that no - or at least not significant - tension is created between the container 2 and the housing 1.
  • Attachments 4, e.g. hoses and valves and the like, are arranged above or inside the foam block 5, which can absorb these due to its elasticity or flexibility.
  • the housing 1 is designed to be completely enclosing.
  • the housing 1 can be made of plastics and/or metal.
  • the cover layers are each made of stainless steel and the side walls are made of polyethylene (specifically: high density polyethylene, HDPE).
  • the completely closed design of the housing 1 ensures protection against access to the container 2.
  • a closure or seal could also be attached, which can prevent or at least make visible manipulation during the transport process or in the warehouse.
  • the foam 3 can preferably be designed in such a way that it is relatively yielding and flexible at room temperature (and slightly negative temperatures) and hardens at lower temperatures (- 15° C and colder) and encloses the container 2 arranged in the housing 1 and protects it from relative movement.
  • the container 2 protected in this way cannot be bent or compressed because the relative movement to the housing 1 is prevented. This can prevent breakages and leaks in the container 2, which is made of plastic, for example.
  • visco-elastic foam can be used as foam, which hardens at certain negative temperatures.
  • the freezing of the arrangement of housing 1 and filled container 2 can be done, for example, by contact cooling systems or circulating air cooling systems or in some other way.
  • contact cooling systems the cover surfaces of the housing 1 (also referred to as the "shell") rest on cooled surfaces.
  • circulating air cooling systems the housing 1 is flushed with cooled air.
  • the individual sides of the housing 1, in particular the cover surfaces (i.e. top and bottom), can be made of relatively thin material, in particular steel, in order to achieve rapid heat conduction (or cold conduction).
  • the housings 1 according to the invention can - as already mentioned - be reused, especially if the foam 3 is designed in such a way that curing is reversible at low temperatures.
  • a single use of the housing 1 is also conceivable.
  • the housing 1 can be easily dismantled for simple recycling measures.

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Packages (AREA)
  • Buffer Packaging (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Claims (10)

  1. Boîtier pour un contenant (2) flexible destiné au transport de liquides, en particulier de médicaments, lequel est habillé au moins en partie d'une mousse (3, 5) élastique, caractérisé en ce que le boîtier (1) est réalisé sensiblement parallélépipédique et est habillé de telle sorte avec la mousse (3, 5) qu'une expansion de volume survenant lors de la congélation du contenant (2) disposé dans le boîtier (1) est compensée au moins en partie par la mousse (3, 5), dans lequel des surfaces de recouvrement du boîtier (1) sont constituées d'acier.
  2. Boîtier selon la revendication 1, caractérisé en ce que le boîtier (1) est habillé de telle sorte avec la mousse (3, 5) qu'une expansion de volume survenant lors de la congélation du contenant (2) disposé dans le boîtier (1) est compensée sensiblement totalement par la mousse (3, 5).
  3. Boîtier selon l'une quelconque des revendications précédentes, caractérisé en ce que la mousse (3, 5) présente une baisse d'élasticité au fur et à mesure que la température baisse sous le point de congélation.
  4. Boîtier selon l'une quelconque des revendications précédentes, caractérisé en ce que la mousse (3, 5) durcit sensiblement à une température entre 0 °C et -30 °C, de manière préférée entre -5 °C et -25 °C et de manière particulièrement préférée entre -10 °C et -20 °C.
  5. Boîtier selon la revendication 4, caractérisé en ce que le processus du durcissement est réversible.
  6. Boîtier selon l'une quelconque des revendications précédentes, caractérisé en ce que le boîtier (1) est habillé de telle sorte avec la mousse (3, 5) que le contenant (2) - de préférence y compris d'éventuels composants rapportés (4) - est entouré en totalité de la mousse (3, 5) quand le contenant (2) est disposé dans le boîtier (1).
  7. Boîtier selon la revendication 6, caractérisé en ce qu'un bloc de mousse (5) est prévu dans le boîtier (1) pour loger les composants rapportés (4).
  8. Ensemble composé d'un boîtier selon l'une quelconque des revendications précédentes et d'un contenant (2) flexible disposé dans celui-ci, rempli d'un liquide, en particulier d'un médicament.
  9. Utilisation d'un boîtier selon l'une quelconque des revendications 1 à 8, dans laquelle un liquide, en particulier un médicament, est rempli dans le contenant (2) flexible, le contenant (2) rempli est disposé dans le boîtier (1) et le liquide est congelé par le refroidissement de l'ensemble composé du boîtier (1) et du contenant (2).
  10. Utilisation selon la revendication 9, caractérisée en ce qu'au moins une couche supplémentaire de mousse (3, 5) est disposée dans le contenant (2) quand le contenant (2) flexible est rempli seulement à une partie de sa contenance.
EP22153960.4A 2017-01-16 2018-01-15 Logement pour un récipient souple Active EP4032824B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP24212454.3A EP4484329A3 (fr) 2017-01-16 2018-01-15 Boîtier pour un récipient souple

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AT600042017 2017-01-16
ATGM50100/2017U AT15857U1 (de) 2017-01-16 2017-05-24 Gehäuse für einen flexiblen Behälter
EP18705541.3A EP3509956B1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible
PCT/AT2018/060010 WO2018129576A1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP18705541.3A Division EP3509956B1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible
EP18705541.3A Division-Into EP3509956B1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP24212454.3A Division-Into EP4484329A3 (fr) 2017-01-16 2018-01-15 Boîtier pour un récipient souple
EP24212454.3A Division EP4484329A3 (fr) 2017-01-16 2018-01-15 Boîtier pour un récipient souple

Publications (3)

Publication Number Publication Date
EP4032824A1 EP4032824A1 (fr) 2022-07-27
EP4032824C0 EP4032824C0 (fr) 2024-12-18
EP4032824B1 true EP4032824B1 (fr) 2024-12-18

Family

ID=62839098

Family Applications (3)

Application Number Title Priority Date Filing Date
EP24212454.3A Pending EP4484329A3 (fr) 2017-01-16 2018-01-15 Boîtier pour un récipient souple
EP18705541.3A Active EP3509956B1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible
EP22153960.4A Active EP4032824B1 (fr) 2017-01-16 2018-01-15 Logement pour un récipient souple

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP24212454.3A Pending EP4484329A3 (fr) 2017-01-16 2018-01-15 Boîtier pour un récipient souple
EP18705541.3A Active EP3509956B1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible

Country Status (6)

Country Link
US (3) US11207239B2 (fr)
EP (3) EP4484329A3 (fr)
CN (1) CN109890716B (fr)
DK (1) DK3509956T3 (fr)
ES (1) ES2999645T3 (fr)
WO (1) WO2018129576A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT521596A1 (de) 2018-09-05 2020-03-15 Single Use Support Gmbh Kühlplattenanordnung und Verfahren
WO2020100028A1 (fr) 2018-11-12 2020-05-22 Smartfreez, Lda Isolant pour empêcher des dommages et une rupture de récipient provoqués par la congélation de solutions aqueuses contenant des matériaux biologiques
EP3926277A1 (fr) 2020-06-19 2021-12-22 Single Use Support GmbH Congélateur à plaques
ES2994341T3 (en) 2020-09-02 2025-01-22 Single Use Support Gmbh Arrangement comprising a container and a bag, method and usage
ES2992754T3 (en) 2020-12-16 2024-12-17 Single Use Support Gmbh Method for protecting tubing
US12239127B2 (en) 2021-07-28 2025-03-04 Sartorius Stedim North America Inc. Thermal capacitors, systems, and methods for rapid freezing or heating of biological materials
EP4166884A1 (fr) 2021-10-15 2023-04-19 Single Use Support GmbH Plaque de refroidissement et procédé de fabrication d'une plaque de refroidissement
EP4169499A1 (fr) 2021-10-19 2023-04-26 Single Use Support GmbH Procédé et dispositif de refroidissement ou de chauffage de fluides bio-pharmaceutiques
CN114471754A (zh) * 2021-12-27 2022-05-13 利穗科技(苏州)有限公司 一种用于生物材料水溶液的容器
CN116853682A (zh) * 2022-03-28 2023-10-10 浙江菜鸟供应链管理有限公司 一种包装设备和一种包装检测系统
EP4718004A1 (fr) 2024-09-30 2026-04-01 Single Use Support GmbH Dispositif de congélation ou de décongélation

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Also Published As

Publication number Publication date
US11207239B2 (en) 2021-12-28
WO2018129576A1 (fr) 2018-07-19
US20250268794A1 (en) 2025-08-28
EP4032824A1 (fr) 2022-07-27
EP4032824C0 (fr) 2024-12-18
CN109890716A (zh) 2019-06-14
EP3509956B1 (fr) 2022-03-09
ES2999645T3 (en) 2025-02-26
US20220047457A1 (en) 2022-02-17
US11602487B2 (en) 2023-03-14
EP4484329A3 (fr) 2025-03-19
DK3509956T3 (da) 2022-04-11
EP4484329A2 (fr) 2025-01-01
EP3509956A1 (fr) 2019-07-17
CN109890716B (zh) 2022-04-26
US20190224074A1 (en) 2019-07-25

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