EP4484329A2 - Boîtier pour un récipient souple - Google Patents

Boîtier pour un récipient souple Download PDF

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Publication number
EP4484329A2
EP4484329A2 EP24212454.3A EP24212454A EP4484329A2 EP 4484329 A2 EP4484329 A2 EP 4484329A2 EP 24212454 A EP24212454 A EP 24212454A EP 4484329 A2 EP4484329 A2 EP 4484329A2
Authority
EP
European Patent Office
Prior art keywords
housing
foam
container
flexible container
housing according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24212454.3A
Other languages
German (de)
English (en)
Other versions
EP4484329A3 (fr
Inventor
Thomas Wurm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Single Use Support GmbH
Original Assignee
Single Use Support GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=62839098&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP4484329(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from ATGM50100/2017U external-priority patent/AT15857U1/de
Application filed by Single Use Support GmbH filed Critical Single Use Support GmbH
Publication of EP4484329A2 publication Critical patent/EP4484329A2/fr
Publication of EP4484329A3 publication Critical patent/EP4484329A3/fr
Pending legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02—Internal fittings
    • B65D25/10—Devices to locate articles in containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1468—Containers characterised by specific material properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/16—Holders for containers
    • A61J1/165—Cooled holders, e.g. for medications, insulin, blood or plasma
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/14—Linings or internal coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/02—Wrapped articles enclosed in rigid or semi-rigid containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/04—Articles or materials enclosed in two or more containers disposed one within another
    • B65D77/06—Liquids or semi-liquids or other materials or articles enclosed in flexible containers disposed within rigid containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/02—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
    • B65D81/022—Containers made of shock-absorbing material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/02—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
    • B65D81/05—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents
    • B65D81/107—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents using blocks of shock-absorbing material
    • B65D81/113—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents using blocks of shock-absorbing material of a shape specially adapted to accommodate contents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers

Definitions

  • the present invention relates to a housing for a flexible container for transporting liquids, in particular drugs.
  • liquids in particular drugs.
  • other liquids that occur in the (bio)pharmaceutical production process can also be transported by means of a flexible container in such a housing.
  • Flexible containers that transport medicines in a housing are also known as “single use bags”. This is usually done in a frozen state, with the flexible container being placed in the housing before freezing. The liquid is then frozen by cooling the arrangement.
  • the volume expansion during freezing (about 8%) creates a pressure on the housing and the flexible container that should not be underestimated. This introduces the risk of mechanical damage and, as a result, leaks in the mechanical container.
  • the object of the present invention is to reduce the mechanical stress on the flexible container and the housing during freezing compared to the prior art.
  • an elastic foam in other words: by at least one body made of elastic Foam - with which the housing is lined.
  • This can in particular at least partially - preferably essentially completely - compensate for the volume expansion of the container arranged in the housing that occurs during freezing. Protection is also sought for an arrangement comprising a housing according to the invention and a flexible container filled with a liquid, in particular a drug, arranged therein.
  • a housing according to the invention wherein a liquid, in particular a drug, is filled into the flexible container, the filled container is arranged in the housing and the liquid is frozen by cooling the arrangement of housing and container.
  • Liquids that can be transported in the flexible container include protein solutions, end products of purification, antibody solutions and other high-quality intermediate products in the pharmaceutical production cycle, as well as, of course, the drugs themselves.
  • the foam exhibits decreasing elasticity as the temperature falls below freezing. It may also be provided that the foam essentially hardens at a temperature between 0° C and -30° C, preferably between -5° C and -25° C and particularly preferably between -10° C and -20° C. These measures may help ensure that the flexible container in the housing lies in a precisely adjusted "bed” in the housing. All forces acting on the flexible container and the housing are thus absorbed by larger surfaces. Damage caused by clamping or the like is at least reduced, if not completely eliminated.
  • the foam is designed in such a way that the curing process is reversible.
  • the elasticity of the foam is available again and thus offers a certain degree of protection against impacts on the flexible container when it is removed from the housing.
  • the reversible process means that the housing can in principle be reused if desired.
  • the curing of the foam can also be referred to as solidification. This is not the curing that occurs during the production of the foam, but rather the change in the elastic properties under the influence of cold.
  • the housing is lined with the foam in such a way that the container - preferably including any attachments - is completely surrounded by the foam when the container is arranged in the housing. This means that not only the flexible container, but also the attachments can be even better protected against damage.
  • attachments for such flexible containers often have different shapes, for example because they consist of deformable hoses and the like, a foam block in the housing that can accommodate the attachments (by deformation) can be advantageous.
  • the housing can be essentially cuboid-shaped. This can, for example, make it easier to stack the housings.
  • the flexible container 2 is arranged inside the housing 1.
  • the housing 1 is lined with foam 3 and a foam block 5. If the liquid inside the container 2 freezes, the container 2 expands. This volume expansion is absorbed by the foam 3 and the Foam block 5 is accommodated so that no - or at least no significant - tension is created between the container 2 and the housing 1.
  • Attachments 4, e.g. hoses and valves and the like, are arranged above or within the foam block 5, which can accommodate them due to its elasticity or flexibility.
  • the housing 1 is designed to be completely enclosing.
  • the housing 1 can be made of plastics and/or metal.
  • the cover layers are each made of stainless steel and the side walls are made of polyethylene (specifically: high density polyethylene, HDPE).
  • the completely closed design of the housing 1 ensures protection against access to the container 2.
  • a closure or seal could also be attached, which can prevent or at least make visible manipulation during the transport process or in the warehouse.
  • the foam 3 can preferably be designed in such a way that it is relatively yielding and flexible at room temperature (and slightly negative temperatures) and hardens at lower temperatures (- 15° C and colder) and encloses the container 2 arranged in the housing 1 and protects it from relative movement.
  • the container 2 protected in this way cannot be bent or compressed because the relative movement to the housing 1 is prevented. This can prevent breakages and leaks in the container 2, which is made of plastic, for example.
  • viscoelastic foam can be used as foam, which hardens at certain negative temperatures.
  • the freezing of the arrangement of housing 1 and filled container 2 can be done, for example, by contact cooling systems or circulating air cooling systems or in some other way.
  • contact cooling systems the cover surfaces of the housing 1 (also referred to as the "shell") rest on cooled surfaces.
  • circulating air cooling systems the housing 1 is flushed with cooled air.
  • the individual sides of the housing 1, in particular the cover surfaces (i.e. top and bottom), can be made of relatively thin material, in particular steel, in order to achieve rapid heat conduction (or cold conduction).
  • the housings 1 according to the invention can - as already mentioned - be reused, especially if the foam 3 is designed in such a way that curing is reversible at low temperatures.
  • a single use of the housing 1 is also conceivable.
  • the housing 1 can be easily dismantled for simple recycling measures.

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Packages (AREA)
  • Buffer Packaging (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
EP24212454.3A 2017-01-16 2018-01-15 Boîtier pour un récipient souple Pending EP4484329A3 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AT600042017 2017-01-16
ATGM50100/2017U AT15857U1 (de) 2017-01-16 2017-05-24 Gehäuse für einen flexiblen Behälter
EP22153960.4A EP4032824B1 (fr) 2017-01-16 2018-01-15 Logement pour un récipient souple
EP18705541.3A EP3509956B1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible
PCT/AT2018/060010 WO2018129576A1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible

Related Parent Applications (3)

Application Number Title Priority Date Filing Date
EP18705541.3A Division EP3509956B1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible
EP22153960.4A Division EP4032824B1 (fr) 2017-01-16 2018-01-15 Logement pour un récipient souple
EP22153960.4A Division-Into EP4032824B1 (fr) 2017-01-16 2018-01-15 Logement pour un récipient souple

Publications (2)

Publication Number Publication Date
EP4484329A2 true EP4484329A2 (fr) 2025-01-01
EP4484329A3 EP4484329A3 (fr) 2025-03-19

Family

ID=62839098

Family Applications (3)

Application Number Title Priority Date Filing Date
EP18705541.3A Active EP3509956B1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible
EP24212454.3A Pending EP4484329A3 (fr) 2017-01-16 2018-01-15 Boîtier pour un récipient souple
EP22153960.4A Active EP4032824B1 (fr) 2017-01-16 2018-01-15 Logement pour un récipient souple

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP18705541.3A Active EP3509956B1 (fr) 2017-01-16 2018-01-15 Logement pour contenant flexible

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP22153960.4A Active EP4032824B1 (fr) 2017-01-16 2018-01-15 Logement pour un récipient souple

Country Status (6)

Country Link
US (3) US11207239B2 (fr)
EP (3) EP3509956B1 (fr)
CN (1) CN109890716B (fr)
DK (1) DK3509956T3 (fr)
ES (1) ES2999645T3 (fr)
WO (1) WO2018129576A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT521596A1 (de) 2018-09-05 2020-03-15 Single Use Support Gmbh Kühlplattenanordnung und Verfahren
CA3111607A1 (fr) 2018-11-12 2020-05-22 Smartfreez Lda Isolant pour empecher des dommages et une rupture de recipient provoques par la congelation de solutions aqueuses contenant des materiaux biologiques
EP3926277A1 (fr) 2020-06-19 2021-12-22 Single Use Support GmbH Congélateur à plaques
EP3964453B1 (fr) 2020-09-02 2024-10-30 Single Use Support GmbH Arrangement comprenant un conteneur et un sac, procédé et utilisation
ES2992754T3 (en) 2020-12-16 2024-12-17 Single Use Support Gmbh Method for protecting tubing
US12239127B2 (en) 2021-07-28 2025-03-04 Sartorius Stedim North America Inc. Thermal capacitors, systems, and methods for rapid freezing or heating of biological materials
EP4166884A1 (fr) 2021-10-15 2023-04-19 Single Use Support GmbH Plaque de refroidissement et procédé de fabrication d'une plaque de refroidissement
EP4169499A1 (fr) 2021-10-19 2023-04-26 Single Use Support GmbH Procédé et dispositif de refroidissement ou de chauffage de fluides bio-pharmaceutiques
CN114471754A (zh) * 2021-12-27 2022-05-13 利穗科技(苏州)有限公司 一种用于生物材料水溶液的容器
CN116853682A (zh) * 2022-03-28 2023-10-10 浙江菜鸟供应链管理有限公司 一种包装设备和一种包装检测系统

Family Cites Families (19)

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Publication number Priority date Publication date Assignee Title
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US4723974A (en) * 1985-07-26 1988-02-09 Ammerman Stephen W Transporting container for an amputated extremity
US4738364A (en) * 1987-03-24 1988-04-19 Medicool, Inc. Portable medicine protector
IT220372Z2 (it) * 1989-04-03 1993-09-20 Qts Srl Contenitore termico portatile per fiale di insulina ed altro materiale occorrente per iniezioni a diabetici e medicinali simili.
US6401484B2 (en) * 1999-09-30 2002-06-11 Gano, Iii John Henry Transport container
US6554133B1 (en) * 2000-07-11 2003-04-29 Hewlett-Packard Development Company, L.P. Container package for packaging electronic devices including multimedia devices such as entire computer system including a computer case, a monitor, and a printer
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GB2383402A (en) * 2001-08-10 2003-06-25 Adrian Peter Copeland Heat-insulated container
DE10155150C2 (de) 2001-11-12 2003-09-11 Ghassan Sowan Versandtasche für thermisch empfindliches Material und damit aufgebaute Transportverpackung
EP1396440A1 (fr) * 2002-09-05 2004-03-10 The Procter & Gamble Company Produit emballé comprenant des poches flexibles remplies de liquide
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US8177123B2 (en) * 2008-09-24 2012-05-15 Sartorius Stedim North America Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
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Also Published As

Publication number Publication date
EP3509956B1 (fr) 2022-03-09
US11602487B2 (en) 2023-03-14
EP4032824C0 (fr) 2024-12-18
EP3509956A1 (fr) 2019-07-17
WO2018129576A1 (fr) 2018-07-19
CN109890716A (zh) 2019-06-14
US20220047457A1 (en) 2022-02-17
DK3509956T3 (da) 2022-04-11
EP4484329A3 (fr) 2025-03-19
ES2999645T3 (en) 2025-02-26
US11207239B2 (en) 2021-12-28
US20250268794A1 (en) 2025-08-28
US20190224074A1 (en) 2019-07-25
EP4032824B1 (fr) 2024-12-18
EP4032824A1 (fr) 2022-07-27
CN109890716B (zh) 2022-04-26

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