EP4565068A1 - Composition comprenant un fongicide phtalimide et un co-fongicide - Google Patents

Composition comprenant un fongicide phtalimide et un co-fongicide

Info

Publication number
EP4565068A1
EP4565068A1 EP23762024.0A EP23762024A EP4565068A1 EP 4565068 A1 EP4565068 A1 EP 4565068A1 EP 23762024 A EP23762024 A EP 23762024A EP 4565068 A1 EP4565068 A1 EP 4565068A1
Authority
EP
European Patent Office
Prior art keywords
composition
fungicide
formula
amount
phthalimide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP23762024.0A
Other languages
German (de)
English (en)
Inventor
Liron HEVRONI
Hanan Sertchook
Eliyahu SHMOELI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adama Makhteshim Ltd
Original Assignee
Adama Makhteshim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adama Makhteshim Ltd filed Critical Adama Makhteshim Ltd
Publication of EP4565068A1 publication Critical patent/EP4565068A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P3/00—Fungicides
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A01N47/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing >N—S—C≡(Hal)3 groups

Definitions

  • the present invention is related to composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) an amount of carboxamide solvent of the Formula A.
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl- C6-alkyl.
  • the present invention also provides methods of use of the composition disclosed herein and processes of preparing the composition disclosed herein.
  • Combinations of phthalimide fungicide with different fungicides were found as very effective for controlling various pathogens on different crops.
  • Phthalimide fungicides are contact fungicides, which are very effective while a level of phytotoxicity can occur in the presence of a penetration enhancer.
  • the phthalimide are very sensitive fungicides which are affected by different parameters.
  • Known commercial products comprising phthalimide fungicide as solo active ingredient and in combination with additional fungicide are suspension concentrate and WDG.
  • Other fungicides in absence of phthalimide may be formulated in different compositions such as suspension concentrate (SC), water dispersible granules (WDG), emulsifiable concentrate (EC) and emulsion concentrate (EW).
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl
  • the composition further comprises pH adjuster.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water (4) pH adjuster and (5) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl.
  • the pH of the composition is between 3 to 6.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) an amount of carboxamide solvent of Formula A, R-C0-NR1R2 (A), wherein:
  • R represents C8 and higher alkyl chain, R1 and R2 represent H and/or Cl -C6-alkyl;
  • the co-fungicide is fluxapyroxad .
  • the co-fungicide is fenpicoxamid.
  • the present invention provides a process for preparing a composition comprising phthalimide fungicide, at least one co-fungicide, water and carboxamide solvent of Formula A,
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl; the process comprising:
  • composition (A) is suspension concentrate (SC) composition of phthalimide fungicide and at least one surfactant
  • composition (B) comprising co-fungicide, carboxamide solvent of Formula A and at least one surfactant, wherein the co fungicide is dissolved in carboxamide solvent of Formula A;
  • the present invention provides a method of controlling fungal disease comprising applying to the plant or the locus of the plant a composition comprising (1) at least one co-fungicide; (2) at least one phthalimide fungicide, (3) water and (4) carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein: (a) R represents C8 and higher alkyl chain, R1 and R2 represent H and/or C 1 - C6-alkyl; (b) the phthalimide fungicide is suspended in the water and (c) the co- fungicide is dissolved in the carboxamide solvent of Formula A.
  • the co-fungicide is fluxapyroxad .
  • the co-fungicide is fenpicoxamid.
  • an "agriculturally acceptable additive” is a compound that is known and accepted in the art for use in the formation of compositions for agricultural or horticultural use.
  • adjuvant is defined as any substance that is not an active ingredient but which enhances or is intended to enhance the effectiveness of the active ingredient, for example pesticide, with which it is used.
  • adjuvants may include, but are not limited to, spreading agents, penetrants, compatibility agents, and drift retardants.
  • plant includes reference to the whole plant, plant organ (e.g., leaves, stems, twigs, roots, trunks, limbs, shoots, fruits etc.), or plant cells.
  • plant organ e.g., leaves, stems, twigs, roots, trunks, limbs, shoots, fruits etc.
  • plant includes reference to agricultural crops including field crops (soybean, maize, wheat, rice, cereal, etc.), vegetable crops (potatoes, cabbages, etc.) and fruits (peach, etc.).
  • propagation material is to be understood to denote all the generative parts of the plant such as seeds and spores, vegetative structures such as bulbs, corms, tubers, rhizomes, roots stems, basal shoots, stolons and buds.
  • locus includes not only areas where insect may already exist, but also areas where insect has yet to emerge, and also to areas under cultivation.
  • stable refers to pH of the composition before storage and/or after storage that is equal to or more than 3.
  • storage refer to at least 1 year of storage at temperature up to In some embodiments, storage refer to any standard accelerated storage stability test (e.g. 2 weeks of storage at a temperature of 54°C).
  • pH remained between 3-6.
  • ha refers to hectare
  • the term “substantially free” when used in connection with a component in the composition means that the amount of the component in the composition is 0.1% w/w or less based on the total weight of the composition.
  • Stability of suspoemulsion composition which comprises phthalimide fungicide and at least one co-fungicide, wherein the phthalimide is suspended in water and the cofungicide is dissolved in a non-aqueous solvent is affected by different parameters such as type and amount of the non-aqueous solvents.
  • solubility of the nonaqueous solvent in water affects the stability of the concentrated composition and stability of the diluted composition in the tank.
  • R-CO-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl- C6-alkyl, which are known as penetration enhancer are compatible with phthalimide fungicide such as folpet and captan.
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl- C6-alkyl also disclosed as carboxamide solvent of Formula A.
  • R is an unbranched or branched, saturated or unsaturated.
  • R is C8-C20 alkyl chain such as n-octyl, n- decyl, n-decenyl.
  • R1 and R2 are identical or different and are unbranched or branched.
  • compositions as well as their methods of use and processes of preparation, are described below.
  • the present invention provides a combination of (1) phthalimide fungicide and (2) carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represent H and/or Cl -C6- alkyl.
  • the combination is a composition.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) an amount of carboxamide solvent of Formula A
  • the present invention provides a composition for controlling fungal disease comprising (1) at least one co-fungicide, (2) at least one phthalimide fungicide, (3) water and (4) carboxamide solvent of Formula A,
  • R-C0-NR1R2 (A) wherein: (a) R represents C8 and higher alkyl chain, R1 and R2 represent H and/or C 1 - C6-alkyl; (b) the phthalimide fungicide is suspended in the water and (c) the cofungicide is dissolved in the carboxamide solvent of Formula A.
  • the composition further comprises pH adjuster.
  • composition further comprising non polar solvent(s)
  • the co-fungicide(s) is dissolved in the mixture of carboxamide solvent of Formula A and non-polar solvent.
  • the present invention provides a composition for controlling fungal disease comprising (1) at least one co-fungicide, (2) at least one phthalimide fungicide, (3) water and (4) mixture of carboxamide solvent of Formula A, R-C0-NR1R2 (A) and non polar solvent, wherein: (a) R represents C8 and higher alkyl chain, R1 and R2 represent H and/or C 1 - C6-alkyl; (b) the phthalimide fungicide is suspended in the water and (c) the co- fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water (4) pH adjuster and (5) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non polar solvent, wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl -C6-alkyl.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water (4) pH adjuster and (5) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water (4) pH adjuster and (5) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl and (2) and the pH of the composition is equal to or more than 3.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) pH adjuster and (5) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl and (2) and the pH of the composition is between 3 to 6.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) pH adjuster and (5) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non polar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl -C6-alkyl and (2) the pH of the composition is equal to or more than 3.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) pH adjuster and (5) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non polar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl -C6-alkyl and (2) the pH of the composition is between 3 to 6.
  • the phthalimide fungicide is suspended in the water and the cofungicide is dissolved in the carboxamide solvent of Formula A.
  • the phthalimide fungicide is suspended in the water and the co- fungicideis dissolved in the mixture of carboxamide solvent of Formula A and nonpolar solvent.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non-polar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl-C6-alkyl, (2) the phthalimide fungicide is suspended in the water and (3) the co-fungicide is dissolved in the mixture of carboxamide solvent of Formula A and nonpolar solvent.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or C 1 - C6-alkyl, (2) the phthalimide fungicide is suspended in the water and (3) the co- fungicide is dissolved in the carboxamide solvent of Formula A.
  • the composition further comprises pH adjuster.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water (4) pH adjuster and (5) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and nonpolar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl-C6-alkyl, (2) the phthalimide fungicide is suspended in the water and (3) the co-fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water (4) pH adjuster and (5) an amount of carboxamide solvent of Formula A
  • R represents C8 and higher alkyl chain
  • R1 and R2 represents H and/or Cl-C6-alkyl
  • the phthalimide fungicide is suspended in the water and (3) the co- fungicide is dissolved in the carboxamide solvent of Formula A.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water (4) pH adjuster and (5) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or C 1 - C6-alkyl and (2) and the pH of the composition is equal to or more than 3, (3) the phthalimide fungicide is suspended in the water and (4) the co-fungicide is dissolved in the carboxamide solvent of Formula A.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) pH adjuster and (5) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl and (2) and the pH of the composition is between 3 to 6, (3) the phthalimide fungicide is suspended in the water and (4) the co-fungicide is dissolved in the carboxamide solvent of Formula A.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) pH adjuster and (5) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non polar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl -C6-alkyl and (2) the pH of the composition is equal to or more than 3, (3) the phthalimide fungicide is suspended in the water and (4) the co-fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide, (3) water and (4) pH adjuster and (5) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non polar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl-C6-alkyl (2) the pH of the composition is between 3 to 6, (3) the phthalimide fungicide is suspended in the water and (4) the co-fungicide is dissolved in the mixture of carboxamide solvent of Formula A and nonpolar solvent.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide (2) an amount of at least one co-fungicide, (3) water and (4) carboxamide solvent of Formula A, wherein the phthalimide fungicide is suspended in water and the co-fungicide is dissolved in the carboxamide solvent of Formula A.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of at least one co-fungicide (3) water and (4) an amount of carboxamide solvent of Formula A, R-C0-NR1R2 (A), wherein:
  • R represents C8 and higher alkyl chain, R1 and R2 represent H and/or C 1 -C6-alkyl;
  • co-fungicide is selected from the group consisting of fluxapyroxad, fenpicoxamid and any combination thereof.
  • the co-fungicide is SDHI fungicide.
  • the co-fungicide is fluxapyroxad.
  • the co-fungicide is Qil fungicide.
  • the co-fungicide is fenpicoxamid.
  • phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof.
  • the phthalimide fungicide is folpet.
  • the phthalimide fungicide is captan.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting of consisting of SDHI, Qil and any combination thereof, (3) water and (4) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non polar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl-C6-alkyl, (2) the phthalimide fungicide is suspended in the water and (3) the co-fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting of SDHI, Qil and any combination thereof, (3) water and (4) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl, (2) the phthalimide fungicide is suspended in the water and (3) the co- fungicide is dissolved in the carboxamide solvent of Formula A.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting offluxapyroxad, fenpicoxamid and any combination thereof, (3) water and (4) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non polar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl-C6-alkyl, (2) the phthalimide fungicide is suspended in the water and (3) the co-fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting offluxapyroxad, fenpicoxamid and any combination thereof, (3) water and (4) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl, (2) the phthalimide fungicide is suspended in the water and (3) the co- fungicide is dissolved in the carboxamide solvent of Formula A.
  • the composition further comprises pH adjuster.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting offluxapyroxad, fenpicoxamid and any combination thereof, (3) water (4) pH adjuster and (5) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non polar solvent, wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl-C6-alkyl, (2) the phthalimide fungicide is suspended in the water and (3) the co-fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting offluxapyroxad, fenpicoxamid and any combination thereof, (3) water (4) pH adjuster and (4) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl, (2) the phthalimide fungicide is suspended in the water and (3) the cofungicide is dissolved in the carboxamide solvent of Formula A.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting offluxapyroxad, fenpicoxamid and any combination thereof, (3) water (4) pH adjuster and (5) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl - C6-alkyl and (2) and the pH of the composition is equal to or more than 3, (3) the phthalimide fungicide is suspended in the water and (4) the co-fungicide is dissolved in the carboxamide solvent of Formula A.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting offluxapyroxad, fenpicoxamid and any combination thereof, (3) water and (4) pH adjuster and (5) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl- C6-alkyl and (2) and the pH of the composition is between 3 to 6, (3) the phthalimide fungicide is suspended in the water and (4) the co-fungicide is dissolved in the carboxamide solvent of Formula A.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting offluxapyroxad, fenpicoxamid and any combination thereof, (3) water and (4) pH adjuster and (5) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and non polar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl -C6-alkyl and (2) the pH of the composition is equal to or more than 3, (3) the phthalimide fungicide is suspended in the water and (4) the co-fungicide is dissolved in mixture of carboxamide solvent of Formula A and non polar solvent.
  • the present invention provides a composition
  • a composition comprising (1) an amount of phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof (2) an amount of at least one co-fungicide is selected from the group consisting offluxapyroxad, fenpicoxamid and any combination thereof, (3) water and (4) pH adjuster and (5) an amount of mixture of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) and nonpolar solvent, wherein (1) R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl-C6-alkyl (2) the pH of the composition is between 3 to 6, (3) the phthalimide fungicide is suspended in the water and (4) the co-fungicide is dissolved mixture of carboxamide solvent of Formula A and nonpolar solvent.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of fluxapyroxad, (3) water and (4) an amount of carboxamide solvent of Formula A
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represent H and/or Cl -C6- alkyl.
  • the present invention provides a composition comprising (1) an amount of phthalimide fungicide, (2) an amount of fluxapyroxad, (3) water and (4) an amount of the dimethyl decan amide, wherein the phthalimide fungicide is suspended in the water and the fluxapyroxad is dissolved in the dimethyl decan amide.
  • the composition further comprises pH adjuster.
  • the amount of the pH adjuster is between 1% to about 5% w/w based on the total weight of the composition.
  • the pH is equal to or more than 3.
  • the pH is between 3 to 6.
  • the pH is equal to or more than 3.5.
  • the pH is between 4 to 5.
  • the pH is between 3.5 to 6.
  • the pH adjuster is a buffer system.
  • composition further comprises buffer system.
  • the buffer system is a combination of citric acid and a base such as citrate salt, hydroxide salt.
  • the buffer system is a combination of acetic acid and a base such as acetate salt, hydroxide salt.
  • the amount of the buffer system is between 1% to about 5% w/w based on the total weight of the composition.
  • the composition is concentrated composition.
  • concentrated refers to the composition before dilution with water (for example, in the tank).
  • the composition is a ready-mix composition.
  • ready-mix refers to a concentrated composition.
  • the composition is storagable.
  • the composition is a stable composition.
  • the composition is a suspo-emulsion composition (SE).
  • the composition comprises additional co-fungicide(s) wherein the additional co-fungicide may be suspended in the water or dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent. In some embodiments, the composition comprises additional co-fungicide(s) wherein the additional co-fungicide may be suspended in the water or dissolved in the carboxamide solvent of Formula A.
  • the phthalimide fungicide is folpet and the co-fungicide is SDHI fungicide.
  • the phthalimide fungicide is folpet and the co-fungicide is fluxapyroxad.
  • the phthalimide fungicide is captan and the co-fungicide is fluxapyroxad.
  • the phthalimide fungicide is folpet and the co-fungicides are DMI fungicide and SDHI fungicide.
  • the phthalimide fungicide is folpet and the co-fungicide are fenpropidin and SDHI fungicide.
  • the phthalimide fungicide is folpet and the co-fungicides are DMI fungicide and Qil fungicide.
  • the phthalimide fungicide is folpet and the co-fungicide is fenpicoxamid.
  • the phthalimide fungicide is captan and the co-fungicide is fenpicoxamid.
  • the phthalimide is folpet and the co-fungicide are DMI fungicide and picoxystrobin.
  • the phthalimide fungicide is folpet and the co-fungicides are SDHI fungicide and picoxystrobin.
  • the R in the carboxamide solvent of Formula A comprises between 8-20 carbon atoms.
  • the composition comprises two or more carboxamide solvents of Formula A R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represent H and/or Cl -C6- alkyl.
  • R is an unbranched or branched, saturated or unsaturated.
  • R1 and R2 are identical or different and an unbranched or branched.
  • the R is C8- C20 alkyl chain.
  • the carboxamide solvent of Formula A is N,N-dimethyl-n- octanamide, N,N-dimethyl-n-nonanamide, N,N-dimethyl-n-decanamide, N,N- dimethyl-n-decenamide N,N-dimethyl-n-dodecanamide and combination thereof.
  • the combination of carboxamide solvent of Formula A is , in particular N,N-dimethyl-n-octanamide and N,N-dimethyl-n-decanamide
  • the carboxamide solvent of Formula A is a mixture of different carboxamide solvents of Formula A, wherein R,R1 and R2 are as defined in the present invention.
  • the carboxamide solvent of Formula A can be individual structure or in the form of mixture of different carboxamide solvents of Formula A, wherein R, R1 and R2 are as defined in the present invention.
  • carboxamide solvent of Formula A as individual structure or mixture are known under the trade names Hallcomid, Genagen or Agnique and which consists of (unless otherwise specified, all percentages are percent by weight).
  • N,N dimethyl decanamide For example 60-100% N,N dimethyl decanamide or for example 60-100% reaction mass of N,N-dimethyl decanamide and N,N dimethyl octanamide.
  • theRl and R2 groups in the carboxamide solvent of Formula A are methyl.
  • the R in the carboxamide solvent of Formula A comprises 10 carbon atoms.
  • the carboxamide solvent of Formula A is N,N-dimethyl-n- octanamide, N,N-dimethyl-n-nonanamide, N,N-dimethyl-n-decanamide, N,N- dimethyl-n-decenamide N,N-dimethyl-n-dodecanamide and combination thereof.
  • carboxamide solvent of Formula A is dimethyl decan amide.
  • the dimethyl decan amide is Genagen 4296.
  • carboxamide solvent of Formula A is dimethyl decen amide.
  • carboxamide solvent of Formula A is Dimethyl 9-decenamide.
  • the dimethyl decen amide is Steposol MET-10U.
  • the composition is stable.
  • the amount of phthalimide fungicide in the composition is between about 1% to about 90% w/w based on the total weight of the composition. In some embodiments, the amount of phthalimide fungicide in the composition is between about 10% to about 80% w/w based on the total weight of the composition. In some embodiments, the amount of phthalimide fungicide in the composition is between about 20% to about 80% w/w based on the total weight of the composition. In some embodiments, the amount of phthalimide fungicide in the composition is between about 15% to about 60% w/w based on the total weight of the composition.
  • the amount of phthalimide fungicide in the composition is between about 15% to about 50% w/w based on the total weight of the composition. In some embodiments, the amount of phthalimide fungicide in the composition is between about 25% to about 35% w/w based on the total weight of the composition. In some embodiments, the amount of phthalimide fungicide in the composition is about 30% w/w based on the total weight of the composition.
  • the amount of co-fungicide in the composition is about 1% w/w based on the total weight of the composition. In some embodiments, the amount of cofungicide in the composition is between about 1% to about 50% w/w based on the total weight of the composition. In some embodiments, the amount of co-ungicide in the composition is between about 25% to about 35% w/w based on the total weight of the composition. In some embodiments, the amount of co-fungicide in the composition is between 1% to 15% w/w based on the total weight of the composition. In some embodiments, the amount of co-fungicide in the composition is between about 1% to about 10% w/w based on the total weight of the composition.
  • the amount of co-fungicide in the composition is between about 1% to about 5% w/w based on the total weight of the composition. In some embodiments, the amount of co- fungicide in the composition is between about 1.25% to about 30% w/w based on the total weight of the composition. In some embodiments, the amount of co-fungicide in the composition is about 2.5% to about 4.5% w/w based on the total weight of the composition.
  • the amount of fluxapyroxad in the composition is about 1% w/w based on the total weight of the composition. In some embodiments, the amount of fluxapyroxad in the composition is between about 1% to about 50% w/w based on the total weight of the composition. In some embodiments, the amount of fluxapyroxad in the composition is between about 1.25% to about 30% w/w based on the total weight of the composition. In some embodiments, the amount of fluxapyroxad in the composition is about 2.5% to about 4.5% w/w based on the total weight of the composition.
  • the amount of one or more carboxamide solvent of Formula A can vary within wide limits, depending on the amount of the co-fungicide.
  • the amount of carboxamide solvent of Formula A in the composition is between about 5 % to 50% w/w based on the total weight of the composition. In some embodiments, the amount of carboxamide solvent of Formula A in the composition is about 8% to about 25 % w/w based on the total weight of the composition. In some embodiments, the amount of carboxamide solvent of Formula A in the composition is about 8% to about 15% w/w based on the total weight of the composition.
  • the amount of water in the composition is between about 20 % to 90% w/w based on the total weight of the composition. In some embodiments, the amount of water in the composition is about 35% to about 45% w/w based on the total weight of the composition. In some embodiments, the amount of water in the composition is about 30% to about 45% w/w based on the total weight of the composition. In some embodiments, the amount of mixture of carboxamide solvent of Formula A and non polar solvent in the composition is between about 5 % to 50% w/w based on the total weight of the composition.
  • the amount of mixture of carboxamide solvent of Formula A and non polar solvent in the composition is about 8% to about 25 % w/w based on the total weight of the composition. In some embodiments, the amount of mixture of carboxamide solvent of Formula A and non polar solvent in the composition is about 8% to about 15% w/w based on the total weight of the composition.
  • the amount of non polar solvent of Formula A in the composition is between about 5 % to 40% w/w based on the total weight of the composition. In some embodiments, the amount of non polar solvent in the composition is about 8% to about 25 % w/w based on the total weight of the composition. In some embodiments, the amount of non polar solvent in the composition is about 8% to about 15% w/w based on the total weight of the composition.
  • the weight ratio between the phthalimide fungicide and the carboxamide solvent of Formula A is between 1 :3 to 4:1. In some embodiments, the weight ratio between the phthalimide fungicide and the carboxamide solvent of Formula A is between 1 : 1 to 3 : 1. In some embodiments, the weight ratio between the phthalimide fungicide and the carboxamide solvent of Formula A is about 1.7:1. In some embodiments, the weight ratio between the phthalimide fungicide and the carboxamide solvent of Formula A is about 1.7:1. In some embodiments, the weight ratio between the phthalimide fungicide and the carboxamide solvent of Formula A is above 1.75:1.
  • the weight ratio between the phthalimide fungicide and the carboxamide solvent of Formula A is between 1.75:1 to 2.2:1. In some embodiments, the weight ratio between the phthalimide fungicide and the carboxamide solvent of Formula A is between 2.8:1 to 3.3:1.
  • the weight ratio between the folpet and the carboxamide solvent of Formula A is between 1 :3 to 4: 1. In some embodiments, the weight ratio between the folpet and the carboxamide solvent of Formula A is between 1 :1 to 3:1. In some embodiments, the weight ratio between the folpet and the carboxamide solvent of Formula A is about 1.7:1. In some embodiments, the weight ratio between the folpet and the carboxamide solvent of Formula A is about 1.8:1. In some embodiments, the weight ratio between the folpet and the carboxamide solvent of Formula A is about 1.75 : 1. In some embodiments, the weight ratio between the Folpet and the carboxamide solvent of Formula Ais between 1.85:1 to2.2:l.
  • the weight ratio between the Folpet and the carboxamide solvent of Formula A is between 1.75:1 to 2.2:1. In some embodiments, the weight ratio between the Folpet and the carboxamide solvent of Formula A is between 2.8:1 to 3.3:1.
  • the weight ratio between the captan and the carboxamide solvent of Formula A is between 1 :3 to 4: 1. In some embodiments, the weight ratio between the captan and the carboxamide solvent of Formula A is between 1 :1 to 3:1. In some embodiments, the weight ratio between the captan and the carboxamide solvent of Formula A is about 1.7:1. In some embodiments, the weight ratio between the captan and the carboxamide solvent of Formula A is about 1.75:1. In some embodiments, the weight ratio between the Captan and the carboxamide solvent of Formula A is between 1.75:1 to 2.2:1. In some embodiments, the weight ratio between the Captan and the carboxamide solvent of Formula A is between 2.8:1 to 3.3:1.
  • the weight ratio between the carboxamide solvent of Formula A to the co-fungicide is between about 3:1 to about 20:1. In some embodiments, the weight ratio between the carboxamide solvent of Formula A to the co-fungicide is between about 3:1 to about 10:1. In some embodiments, the weight ratio between the carboxamide solvent of Formula A to the co-fungicide is between about 3:1 to about 8:1. In some embodiments, the weight ratio between the carboxamide solvent of Formula A to the co-fungicide is between about 4:1 to about 7:1.
  • the weight ratio between the carboxamide solvent of Formula A to the fluxapyroxad is between about 3:1 to about 20:1. In some embodiments, the weight ratio between the carboxamide solvent of Formula A to fluxapyroxad is between about 3:1 to about 10:1. In some embodiments, the weight ratio between the carboxamide solvent of Formula A to fluxapyroxad is between about 4:1 to about 8:1. In some embodiments, the weight ratio between the carboxamide solvent of Formula A to fluxapyroxad is between about 4:1 to about 7:1
  • the weight ratio between the carboxamide solvent of Formula A to the fenpicoxamid is between about 3:1 to about 20:1. In some embodiments, the weight ratio between the carboxamide solvent of Formula A to fenpicoxamid is between about 3:1 to about 10:1. In some embodiments, the weight ratio between the carboxamide solvent of Formula A to fenpicoxamid is between about 4:1 to about 8:1. In some embodiments, the weight ratio between the carboxamide solvent of Formula A to fenpicoxamid is between about 4:1 to about 7:1
  • the composition comprises two co-fungicides
  • the composition comprises more than two co-fungicide.
  • the phthalimide fungicide is suspended in the water, one cofungicide is suspended in the water and the second is dissolved in the carboxamide solvent of Formula A.
  • the phthalimide fungicide is suspended in the water, the cofungicides are dissolved in the carboxamide solvent of Formula A.
  • the phthalimide fungicide is suspended in the water, and at least one co- fungicide is dissolved in the carboxamide solvent of Formula A.
  • the composition comprises two or more co- fungicide
  • the phthalimide fungicide is suspended in the water
  • at least one co- fungicide is dissolved in the carboxamide solvent of Formula A and at least one co- fungicide is suspended in the water.
  • the composition comprises two or more co-fungicides
  • the phthalimide fungicide is suspended in the water, at least two co-fungicides are dissolved in carboxamide solvent of Formula A.
  • the one co-fungicide is suspended in the water and the second is dissolved in the carboxamide solvent of Formula A.
  • the co-fungicides are dissolved in the carboxamide solvent of Formula A.
  • composition when the composition comprises two or more co- fungicides, at least one co- fungicide is dissolved in the carboxamide solvent of Formula A. In some embodiments, when the composition comprises two or more co- fungicide, at least one co- fungicide is dissolved in the carboxamide solvent of Formula A and at least one co- fungicide is suspended in the water.
  • composition comprises two or more co -fungicides
  • at least two co-fungicides are dissolved in the carboxamide solvent of Formula A
  • the phthalimide fungicide is suspended in the water, one cofungicide is suspended in the water and the second is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the phthalimide fungicide is suspended in the water, the cofungicides are dissolved in the mixture of carboxamide solvent of Formula A and nonpolar solvent.
  • the phthalimide fungicide is suspended in the water, and at least one co- fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the phthalimide fungicide when the composition comprises two or more co- fungicide, the phthalimide fungicide is suspended in the water, at least one co- fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent and at least one co- fungicide is suspended in the water.
  • the composition comprises two or more co-fungicides
  • the phthalimide fungicide is suspended in the water, at least two co-fungicides are dissolved in the mixture of carboxamide solvent of Formula A and nonpolar solvent.
  • the one co-fungicide is suspended in the water and the second is dissolved in the mixture of carboxamide solvent of Formula A and nonpolar solvent.
  • the co-fungicides are dissolved in the mixture of carboxamide solvent of Formula A and nonpolar solvent. In some embodiments, when the composition comprises two or more co-fungicides, at least one co-fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • composition when the composition comprises two or more co- fungicide, at least one co- fungicide is dissolved in the mixture of carboxamide solvent of Formula A and nonpolar solvent and at least one co- fungicide is suspended in the water. In some embodiments, when the composition comprises two or more co -fungicides, at least twoco-fungicides are dissolved in the mixture of carboxamide solvent of Formula A and nonpolar solvent.
  • the weight ratio between the phthalimide fungicide and the cofungicide is 80:1 to 1:80. In some embodiments the weight ratio between phthalimide fungicide to co fungicide(s) is 30:1 to 1:1. In some embodiments, the weight ratio between phthalimide fungicide to co-fungicide(s) is 20:1 to 1:1. In some embodiments, the weight ratio between phthalimide fungicide to co-fungicide(s) is 20:1 to 1:1. In some embodiments, the weight ratio between phthalimide fungicide to co-fungicide(s) is 12:1 to 1:1. In some embodiments, the weight ratio between phthalimide fungicide to co-fungicide(s) is 8:1 to 1:1
  • the ratio among phthalimide fungicide and the co-fungicide SDHI fungicide is 1: 0.06. In some embodiments, the ratio among phthalimide fungicide and the co-fungicide SDHI fungicide is 1: 0.8. In some embodiments, the ratio among phthalimide fungicide and the co-fungicide SDHI fungicide is 1:0.1. In another embodiment the ratio is 1:0.12. In some embodiments, the ratio among phthalimide fungicide and the co-fungicide SDHI fungicide is 1:0.17.
  • the weight ratio between phthalimide fungicide to fluxapyroxad is 30:1 to 1:1. In some embodiments, the weight ratio between phthalimide fungicide to fluxapyroxad is 20:1 to 1:1. In some embodiments, the weight ratio between phthalimide fungicide to fluxapyroxad is 20: 1 to 1 : 1. In some embodiments, the weight ratio between phthalimide fungicide to fluxapyroxad is 12:1 to 1:1. In some embodiments, the weight ratio between phthalimide fungicide to fluxapyroxad is 8: 1 to 1:1.
  • the weight ratio between folpet to fluxapyroxad is 30:1 to 1:1. In some embodiments, the weight ratio between folpet to fluxapyroxad is 20:1 to 1:1. In some embodiments, the weight ratio between folpet to fluxapyroxad is 20:1 to 1:1. In some embodiments, the weight ratio between folpet to fluxapyroxad is 12:1 to 1:1. In some embodiments, the weight ratio between folpet to fluxapyroxad is 8:1 to 1:1.
  • the weight ratio between captan to fluxapyroxad is 30:1 to 1:1. In some embodiments, the weight ratio between captan to fluxapyroxad is 20:1 to 1:1. In some embodiments, the weight ratio between captan to fluxapyroxad is 20:1 to 1 :1. In some embodiments, the weight ratio between captan to fluxapyroxad is 12:1 to 1 :1. In some embodiments, the weight ratio between captan to fluxapyroxad is 8:1 to 1 :1
  • the ratio among phthalimide fungicide and the co-fungicides DMI fungicide and SDHI fungicide is 1 :0.03:0.375. In some embodiments, the ratio among phthalimide fungicide and the co-fungicides DMI fungicide and SDHI fungicide is 0.05:0.625:1. In some embodiments, the ratio among phthalimide fungicide and the co-fungicides DMI fungicide and SDHI fungicide is 1 :0.08:0.8. In some embodiments, the ratio among phthalimide fungicide and the co-fungicides DMI fungicide and SDHI fungicide is 0.08:1 :1.
  • the ratio among phthalimide fungicide and the co-fungicides fenpropidin fungicide and SDHI fungicide is 1 :0.03:0.3. In some embodiments, the ratio among phthalimide fungicide and the co-fungicides fenpropidin fungicide and SDHI fungicide is 1 :0.03:0.2. In some embodiments, the ratio among phthalimide fungicide and the co-fungicides fenpropidin fungicide and SDHI fungicide is 1 :0.03: 0.15. In some embodiments, the ratio among phthalimide fungicide and the co- fungicides fenpropidin fungicide and SDHI fungicide is 1 :0.05:0.5.
  • theratio among phthalimide fungicide and the co-fungicides fenpropidin fungicide and SDHI fungicide is 1 :0.05:0.33. In another embodiment the ratio is 1 :0.05:0.25. In some embodiments, the ratio among phthalimide fungicide and the co- fungicides fenpropidin fungicide and SDHI fungicide is 1 :0.08:0.8. In some embodiments, theratio among phthalimide fungicide and the co-fungicides fenpropidin fungicide and SDHI fungicide is 1 :0.08:0.533. In some embodiments, the ratio among phthalimide fungicide and the co-fungicides fenpropidin fungicide and SDHI fungicide is 1 :0.08:0.4.
  • the weight ratio between phthalimide fungicide to fenpicoxamid is 30:1 to 1 :1. In some embodiments, the weight ratio between phthalimide fungicide to fenpicoxamid is 30:1 to 1 :1. In some embodiments, the weight ratio between phthalimide fungicide to fenpicoxamid is 20:1 to 1 :1. In some embodiments, the weight ratio between phthalimide fungicide to fenpicoxamid is 12:1 to 1 :1. In some T1 embodiments, the weight ratio between phthalimide fungicide to fenpicoxamid is 8:1 to 1 :1.
  • the weight ratio between folpet to fenpicoxamid is 30:1 to 1 :1. In some embodiments, the weight ratio between folpet to fenpicoxamid is 30:1 to 1 :1. In some embodiments, the weight ratio between folpet to fenpicoxamid is 20:1 to 1 :1. In some embodiments, the weight ratio between folpet to fenpicoxamid is 12:1 to 1 :1. In some embodiments, the weight ratio between folpet to fenpicoxamid is 8:1 to 1 :1.
  • the weight ratio between captan to fenpicoxamid is 30:1 to 1 :1. In some embodiments, the weight ratio between captan to fenpicoxamid is 30:1 to 1 :1. In some embodiments, the weight ratio between captan to fenpicoxamid is 20:1 to 1 :1. In some embodiments, the weight ratio between captan to fenpicoxamid is 12:1 to 1 :1. In some embodiments, the weight ratio between captan to fenpicoxamid is 8:1 to 1 :1.
  • the ratio among phthalimide fungicide and the co-fungicides DMI fungicide and picoxystrobin fungicide is 1 :0.08:1.3. In some embodiments, the ratio among phthalimide fungicide and the co-fungicides DMI fungicide and picoxystrobin fungicide is 1 :0.1 :1.7.
  • the ratio among phthalimide fungicide and the co-fungicides SDHI fungicide and picoxystrobin fungicide is 1 :0.03:0.5. In some embodiments, the ratio among phthalimide fungicide and the co-fungicides SDHI fungicide and picoxystrobin fungicide 0.05:0.8:1. In some embodiments, the ratio among phthalimide fungicide and the co-fungicides SDHI fungicide and picoxystrobin fungicide 1 :0.08:1.3.
  • the carboxamide solvent of Formula A is as described above.
  • the composition further comprises non polar solvent(s).
  • nonpolar solvent may include but is not limited to aromatic hydrocarbons (e.g. toluene, o-, m-, p-xylene, ethylbenzene, isopropylbenzene, tertbutylbenzene, naphthalenes, mono- or polyalkyl-substituted naphthalenes), paraffins (e.g.
  • aromatic hydrocarbons e.g. toluene, o-, m-, p-xylene, ethylbenzene, isopropylbenzene, tertbutylbenzene, naphthalenes, mono- or polyalkyl-substituted naphthalenes
  • paraffins e.g.
  • octane nonane, decane, undecane, dodecane, tridecane, tetradecane, pentadecane, hexadecane, hepta-decane, octa-decane, nona-decane, eicosane, heneicosane, docosane, tricosane, tetracosane, pentacosane, and branched chain isomers thereof), petroleum, diesel, mineral oil.
  • the composition is substantially free of non polar solvent.
  • the mixture of carboxamide solvent of Formula A and nonpolar solvent further comprises additive such as surfactant.
  • the composition further comprises at least one surfactant.
  • the composition comprises at least two surfactants.
  • the amount of the surfactant(s) in the composition is between about 3% to about 15% w/w based on the total weight of the composition. In some embodiments, the amount of the surfactant(s) in the composition is between about 5% to about 10% w/w based on the total weight of the composition. In some embodiments, the amount of the surfactant(s) is about 6.5% to about 8.5% w/w based on the total weight of the composition.
  • the surfactant is dispersing agent, emulsifier and/or wetting agent.
  • more than one dispersing agent, emulsifier and/or wetting agent is used.
  • the dispersing agent is selected from the group consisting of polyglycol ethers, Polyalkylene oxideblock copolymer (such as atlas G5002L, Ethylan NS 500 LQ, Antarox B/848), ethoxylated fatty alcohol, castor oil ethoxylate, ethoxylated aryl alcohol, their ether phosphates and salts thereof (such as amine salt of Polyarylphenyl ether phosphate), ethoxylated tristyryl phenol, Poly-ether modified Trisiloxane, methyl methacrylate - polyethylene glycol graft copolymer (such as atlox 4913 and tersperse 2500) , condensate of alkyl naphthalene sulfonate formaldehyde, lignosulfonates , silicone surfactant, methyl naphthalene sulfonate condensate, sodium salt, poly electrolyte block copo
  • the dispersing agent is a block polymer comprising 77% of sodium 2-acryloylamino-2-methylpropane-l-sulfonate (AMPS) monomers and 23% of the ethyl acrylate (EA) monomers.
  • the dispersing agent is a water solution of 30% by weight solution of a block polymer comprising 77% of sodium 2-acryloylamino-2- methylpropane-l-sulf onate (AMPS) monomers and 23% of ethyl acrylate (EA) monomers, which may be prepared as described in Example 1 of WO2017/098325.
  • the dispersing agent is a methyl methacrylate - polyethylene glycol graft copolymer.
  • the dispersing agents are a water solution of 30% by weight solution of a block polymer comprising 77% of sodium 2-acryloylamino-2- methylpropane-l-sulf onate (AMPS) monomers and 23% of ethyl acrylate (EA) monomers, which may be prepared as described in Example 1 ofWO2017/098325, and a methyl methacrylate - polyethylene glycol graft copolymer.
  • AMPS sodium 2-acryloylamino-2- methylpropane-l-sulf onate
  • EA ethyl acrylate
  • the wetting agent is dioctyl sulfosuccinate (such as Lankropol KO2) alcohol ethoxylate, sodium lauryl sulfate, sodium alkyl naphthalene sulfonate or combination thereof.
  • the composition further comprises emulsifier.
  • the emulsifier is soluble in the carboxamide solvent of Formula A.
  • the emulsifier is soluble in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the emulsifier is for reducing the solubility of carboxamide solvent of Formula A in the water.
  • the emulsifier agent is Sodium Dioctyl sulfosuccinate (such as aerosol OT-SE), Soprophor ts-10 (ethoxylated tristyryl phenol) , Atlox 4912 (ABA Block copolymer), alkylated Benzenesulfonic acid calcium salt, Castor oil ethoxylate and combination thereof.
  • same surfactant may function in different roles (wetting, emulsifier, dispersing agent).
  • the role is dependent on the composition type (SC, EC, EW) which is used for preparing the invention composition.
  • the amount of emulsifier agent which is dissolved in the carboxamide solvent of Formula A is up to about 2% w/w based on the total weight of the composition.
  • the pH of the composition is between 3 to 6.
  • the pH is equal to or more than 3.
  • composition further comprises buffer system.
  • the buffer system is a combination of citric acid and a base such as citrate salt, hydroxide salt.
  • the buffer system is a combination of acetic acid and a base such as acetate salt, hydroxide salt.
  • the buffer system comprising a mixture of acetic acid and acetic acid sodium, potassium or ammonium salt.
  • the buffer system comprising a mixture of citric acid and citric acid sodium, potassium or ammonium salt.
  • the amount of the buffer system is between 1% to about 5% w/w based on the total weight of the composition.
  • the viscosity of the composition is between 900 to 2000 cP. (measured by Brookefield viscometer, Spindle 63, 12 RPM).
  • the composition further comprises rheological modifier.
  • the rheological modifier is a clay based rheological modifier additive such as Van Gel B (Magnesium Aluminum Silicate), BentoneEW (Hectorite), Bentone LT (Smectite), Attagel (Attepulgite).
  • Van Gel B Magneium Aluminum Silicate
  • BentoneEW Hectorite
  • Bentone LT Bentone LT
  • Attagel Attagel
  • the clay based rheological modifier is Van Gel B (Magnesium Aluminum Silicate).
  • the clay is combined with a xanthan gum (oligosaccharide modifier).
  • the rheological modifier is a silica based rheological modifier additive such as Aerosil 200, Aerosil 380, Cab-O-Sil M5. In some embodiments, the silica based rheological modifier is Cab-O-Sil M5.
  • the silica is combined with a xanthan gum (oligosaccharide modifier).
  • the composition further comprises at least one additive such as anti-foaming agent, biocides, adjuvants, antifreeze.
  • the composition further comprises a polyelectrolyte complex.
  • the poly electrolyte complex is as described in WO 2013/133705 and WO 2013/133706.
  • the polyelectrolyte complex is a complex of a polycation and a polyanion.
  • the present invention provides a composition comprising:
  • folpet in amount of about 25% to about 35% w/w based on the total weight of the composition
  • carboxamide solvent of Formula A in amount of about 10% to about 25% w/w based on the total weight of the composition.
  • the present invention provides a composition comprising:
  • folpet in amount of about 30 % w/w based on the total weight of the composition
  • carboxamide solvent of Formula A in amount of about 15% w/w based on the total weight of the composition.
  • the present invention provides a composition comprising: (1) folpet in amount of about 30 % w/w based on the total weight of the composition,
  • the present invention provides a composition comprising:
  • captan in amount of about 30.5% w/w based on the total weight of the composition
  • carboxamide solvent of Formula A in amount of about 9.6% w/w based on the total weight of the composition.
  • composition further comprising pH adjuster.
  • the pH adjuster is a buffer system.
  • the present invention provides a composition comprising:
  • folpet in amount of about 25% to about 35% w/w based on the total weight of the composition
  • carboxamide solvent of Formula A in amount of about 10% to about 25% w/w based on the total weight of the composition
  • the present invention provides a composition comprising: (1) folpet in amount of about 30 % w/w based on the total weight of the composition,
  • the present invention provides a composition comprising:
  • folpet in amount of about 30 % w/w based on the total weight of the composition
  • the amount of the pH adjuster is between 1% to about 5% w/w based on the total weight of the composition.
  • pH adjuster is buffer system.
  • the buffer system is a combination of citric acid and a base such as citrate salt, hydroxide salt.
  • the amount of the buffer system is between 1% to about 5% w/w based on the total weight of the composition.
  • the present invention provides a composition comprising:
  • captan in amount of about 30.5% w/w based on the total weight of the composition
  • fluxapyroxad in amount of about 2.5% w/w based on the total weight of the composition.
  • carboxamide solvent of Formula A in amount of about 9.6% w/w based on the total weight of the composition.
  • the amount of the pH adjuster is between 1% to about 5% w/w based on the total weight of the composition. In some embodiments, pH adjuster is buffer system.
  • the buffer system is combination of acetic acid and a base such as acetate salt, hydroxide salt.
  • the amount of the buffer system is between 1% to about 5% w/w based on the total weight of the composition.
  • the present invention provides a process for preparing a composition comprising phthalimide fungicide, at least one co-fungicide, water and carboxamide solvent of Formula A,
  • R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represents H and/or Cl- C6-alkyl; the process comprising:
  • composition (A) is suspension concentrate (SC) composition of phthalimide fungicide and at least one surfactant
  • composition (B) comprising co-fungicide, carboxamide solvent of Formula A and at least one surfactant, wherein the co fungicide is dissolved in carboxamide solvent of Formula A;
  • the composition (B) is emulsifiable concentrate (EC) in some embodiments the composition (B) is concentrated emulsion (EW).
  • composition (A) further comprises surfactant(s).
  • the at least one surfactant in compositions (A) and (B) is the same.
  • the buffer is part of the SC composition.
  • composition (B) when the composition (B) is EW, it may further comprise a buffer system.
  • compositions (A) and (B) comprise buffer.
  • the SC composition comprises rheologic modifier(s).
  • the EW composition comprises rheologic modifier(s).
  • the rheologic modifier is added to the SE composition.
  • the composition comprising co-fungicide, carboxamide solvent of Formula A and at least one surfactant further comprises at least one emulsifier.
  • the phthalimide fungicide is formulated as suspension concentrate (SC)
  • the composition (B) which comprises the co-fungicide is prepared by (i) preparing EC composition comprising the co-fungicide and (ii) mixing with water to obtain concentrated emulsion (EW).
  • the composition (B) which comprises co-fungicide is prepared by combining a water phase and an organic phase to obtain concentrated emulsion (EW).
  • the EW composition further comprises, buffer, antifreeze, surfactant(s) and emulsifier(s).
  • the present invention provides a method of controlling fungal disease comprising applying to the plant or the locus of the plant a composition comprising (a) at least one co-fungicide; and b) at least one phthalimide fungicide, (c) water and (d) carboxamide solvent of Formula A.
  • the present invention provides a method of controlling fungal disease comprising applying to the plant or the locus of the plant a composition comprising (1) at least one co-fungicide, (2) at least one phthalimide fungicide, (3) water and (4) carboxamide solvent of Formula A,
  • R-C0-NR1R2 (A) wherein: (a) R represents C8 and higher alkyl chain, R1 and R2 represent H and/or C 1 - C6-alkyl; (b) the phthalimide fungicide is suspended in the water and (c) the co- fungicide is dissolved in the carboxamide solvent of Formula A.
  • the present invention provides a method of controlling fungal disease comprising applying to the plant or the locus of the plant a composition comprising (1) at least one co-fungicide, (2) at least one phthalimide fungicide, (3) water and (4) mixture of carboxamide solvent of Formula A,
  • R-C0-NR1R2 (A) and non polar solvent, wherein: (a) R represents C8 and higher alkyl chain, R1 and R2 represent H and/or Cl -C6-alkyl; (b) the phthalimide fungicideis suspended in the water and (c) the co-fungicide is dissolved in the mixture of carboxamide solvent of Formula A and non polar solvent.
  • the co-fungicide is fluxapyroxad.
  • the co-fungicide is fenpicoxamid.
  • the phthalimide fungicide is folpet.
  • the phthalimide fungicide is captan.
  • composition of the present invention can be combined with additional pesticide such as fungicide and/or insecticide.
  • Non-limiting examples of pathogens of fungal diseases which may be treated in accordance with the invention include: diseases caused by powdery mildew pathogens, for example Blumeria species, for example Blumeria graminis, Podosphaera species, for example Podosphaera leucotricha, Sphaerotheca species, for example Sphaerotheca fuliginea, Uncinula species, for example Uncinula necator, for example Erysiphe species; diseases caused by rust disease pathogens, for example Gymnosporangium species, for example Gymnosporangium sabinae ; Hemileia species, for example Hemileia vastatrix; Phakopsora species, for example Phakopsora pachyrhizi or Phakopsora meibomiae Puccinia species, for example Puccinia recondita, Puccinia graminis oder Puccinia striif ormis, Uromyces species
  • Phytophthora species for example Phytophthora inf estans
  • Plasmopara species for example Plasmopara viticola
  • Pseudoperonospora species for example Pseudoperonospora humuli or Pseudoperonospora cubensis
  • Pythium species for example Pythium ultimunv
  • Cercospora species for example Cercospora beticola
  • Cladiosporium species for example Cladiosporium cucumerinunr
  • Cochliobolus species for example Cochliobolus sativus (conidial form: Drechslera, syn: Helminthosporium) or Cochliobolus miyabeanus
  • C oil etotri chum species for example Colletotric
  • Pseudomonas species for example Pseudomonas syringae pv. lachrymans, Erwinia species, for example Erwinia amylovora, Liberibacter species, for example Liberibacter asiaticus, Xyella species, for example Xylella f astidiosa, Ralstonia species, for example Ralstonia solanacearum, Dickeya species, for example Dickeya solanv, Clavibacter species, for example Clavibacter michiganensis, Streptomyces species, for example Streptomyces scabies, diseases of soya beans: fungal diseases on leaves, stems, pods and seeds caused, for example, by Altemaria leaf spot (Altemaria spec atrans tenuissima), Anthracnose (Colletotrichum gloeosporoides dematium var.
  • Altemaria leaf spot Altemaria spec atrans tenuissima
  • Anthracnose
  • phytophthora rot (Phytophthora megasperma), brown stem rot (Phialophora gregata), pythiumrot (Pythium aphanidermatum, Pythium irregulare, Pythium debaryanum, Pythium myriotylum, Pythium ultimum), rhizoctonia root rot, stem decay, and damping-off (Rhizoctonia solani), sclerotinia stem decay (Sclerotinia sclerotiorum), sclerotinia southern blight (Sclerotinia rolfsii), thielavi opsis root rot (Thielaviopsis basicola).
  • the phytopathogenic harmful fungi is selected from Septoria species, Fusarium species, Puccinia species, Erisyphe species, Drechslera species, Ramularia species, Mycosphaerella species and Rhynchosporium species.
  • the phytopathogenic harmful fungi is selected from Puccinia recondita, Septoria tritici, Fusarium culmorum, Pyrenophora teres, Rhynchosporium secalis and Rhizoctonia solani.
  • the locus is a field of crop, wherein the is selected from the group consisting of cotton, rice, flax, grapevines, fruit, vegetables, such as Rosaceae sp. (for example pome fruit such as apples and pears, but also stone fruit such as apricots, cherries, almonds and peaches, and berry fruits such as strawberries), Ribesioidae sp., Juglandaceae sp., Betulaceae sp., Anacardiaceae sp., Fagaceae sp., Moraceae sp., Oleaceae sp., Actinidaceae sp., Lauraceae sp., Musaceae sp.
  • Rosaceae sp. for example pome fruit such as apples and pears, but also stone fruit such as apricots, cherries, almonds and peaches, and berry fruits such as strawberries
  • Rosaceae sp. for example pome fruit such as
  • Rubiaceae sp. for example coffee
  • Theaceae sp. Sterculiceae sp.
  • Rutaceae sp. for example lemons, organs and grapefruit
  • Solanaceae sp. for example tomatoes
  • Liliaceae sp. for example lettuce
  • Umbelliferae sp. for example lettuce
  • Alliaceae sp. for example leeks, onions
  • main crop plants such as Gramineae sp. (for example maize, turfgrass, cereals such as wheat, rye, rice, barley, oats, sorghum/millet and triticale), Asteraceae sp. (for example sunflowers), Brassicaceae sp. (for example white cabbage, red cabbage, broccoli, cauliflower, Brussels sprouts, Pak Choi, kohlrabi, radishes, and rapeseed, mustard, horseradish and cress), Fabacae sp. (for example beans, peanuts), Papilionaceae sp. (for example soya beans), Solanaceae sp.
  • Gramineae sp. for example maize, turfgrass, cereals such as wheat, rye, rice, barley, oats, sorghum/millet and triticale
  • Asteraceae sp. for example sunflowers
  • Brassicaceae sp. for example white cabbage, red cabbage, broccoli
  • potatoes for example potatoes
  • Chenopodiaceae sp. for example sugar beet, fodder beet, chard, beetroot
  • sugarcane poppies, olives, coconuts, cocoa, tobacco and useful plants and ornamental plants in gardens and forests; and genetically modified varieties of each of these plants, and the seeds of these plants.
  • the crop is selected from the group consisting of wheat, rye, rice, soybean, barley, oats, sorghum/millet, triticale, maize, potatoes, cabbage, rapeseed, beans, sugarcane, peanuts, peaches and sunflowers.
  • the composition including a diluted aqueous composition
  • spraying applications using automatic systems are known to reduce labor costs and are cost-effective. Methodsand equipment well-known to a person skilled in the art can be used for that purpose.
  • the composition, including diluted aqueous composition can be regularly sprayed, when the risk of infection is high. When the risk of infection is lower, spray intervals may be longer.
  • compositions of the invention include, but are not limited to, dipping, watering, drenching, introduction into a dump tank, vaporizing, atomizing, fogging, fumigating, painting, brushing, misting, dusting, foaming, spreading-on, packaging and coating (e.g. by means of wax or electrostatically).
  • the composition including a diluted aqueous composition, may be injected into the soil.
  • the pesticide is applied at a rate effective for controlling a pest. In some embodiments, the pesticide is applied at a rate effective for preventing infestation of the pest.
  • the pesticide is applied at a rate effective for curing infestation of the pest.
  • a method of the invention is effective for preventing infestation of a pest. In some embodiments, the method is effective for curing infestation of the pest.
  • the method is effective for increasing the pesticidal activity of the pesticide, wherein the pesticide is phthalimide fungicide.
  • a method of the invention further comprises applying at least one additional agrochemical to a pest, a plant part, a plant, the locus, or propagation material thereof.
  • Carboxamide solvent of Formula A R-C0-NR1R2 (A) wherein R represents C8 and higher alkyl chain, R1 and R2 represent H and/or Cl -C6- alkyl.
  • R is an unbranched or branched, saturated or unsaturated.
  • R1 and R2 are identical or different and an unbranched or branched.
  • the R is C8- C20 alkyl chain
  • the carboxamide solvent of Formula A is N,N-dimethyl-n- octanamide, N,N-dimethyl-n-nonanamide, N,N-dimethyl-n-decanamide, N,N- dimethyl-n-decenamide N,N-dimethyl-n-dodecanamide and combination thereof.
  • the carboxamide solvent of Formula A may includes but not limited to, N,N-dimethyl-n-octanamide, N,N-dimethyl-n-decanamide and N,N- dimethyl-n-dodecanamide, in particular N,N-dimethyl-n-octanamide and N,N- dimethyl-n-decan amide.
  • the carboxamide solvent of Formula A is in form of mixture.
  • the carboxamide solvent of Formula A is a mixture of different carboxamide solvents of Formula A, wherein R,R1 and R2 are as defined in the present invention.
  • the carboxamide solvent of Formula A can be individual structure or in the form of mixture of different carboxamide solvents of Formula A, wherein R, R1 and R2 are as defined in the present invention.
  • carboxamide solvent of Formula A as individual structure or mixture are known under the trade names Hallcomid, Genagen or Agnique and which consists of (unless otherwise specified, all percentages are percent by weight), for example 60- 100% N,N dimethyl decanamide or for example 60-100% reaction mass of N,N- dimethyl decanamide and N,N dimethyl octanamide.
  • the R in the carboxamide solvent of Formula A comprises between 8-20 carbon atoms. In some embodiments, the R in the carboxamide solvent of Formula A comprises 10 carbon atoms.
  • theRl and R2 groups in the carboxamide solvent of Formula A are methyl.
  • R1 and R2 are different.
  • R1 and R2 are part of cyclic group.
  • the carboxamide solvent of Formula A is dimethyl decanamide.
  • the dimethyl decanamide is Genagen 4296.
  • carboxamide solvent of Formula A is dimethyl decen amide.
  • the dimethyl decen amide is Steposol MET-10U.
  • the carboxamide solvent of Formula A is a dimethylamide based on naturally derived fatty acids.
  • phthalimide fungicide is selected from the group consisting of captan, folpet, captafol and any combination thereof.
  • phthalimide fungicide is mixture of two phthalimide fungicides.
  • the phthalimide fungicide is captan.
  • the phthalimide fungicide is folpet.
  • the phthalimide fungicide is captafol.
  • the co-fungicide(s) is selected from the group consisting of SDHI fungicide, DMI fungicide , Qol fungicide , Qil fungicide , QoSI (quinone outside stigmatellin inhibitors) , amine fungicide and any combination thereof.
  • the co-fungicide is an SDHI fungicide.
  • the co-fungicide is DMI fungicide. In some embodiments, the co-fungicide is Qol fungicide.
  • the co-dungicide is Qil fungicide.
  • the co-fungicide is QoSI fungicide.
  • the co-fungicide is amine fungicide.
  • the co-fungicide is fluxapyroxad .
  • the co-fungicide is fenpicoxamid.
  • the Qil (quinone inside inhibitors) is selected from the group consisting of amisulbrom, cyazofamid, fenpicoxamid and any combination thereof.
  • the Qil (quinone inside inhibitors) is amisulbrom. In some embodiments, the Qil (quinone inside inhibitors) is cyazofamid. In some embodiments, the Qil (quinone inside inhibitors) is fenpicoxamid.
  • the Qol (quinone outside inhibitors) is selected from the group consisting of azoxystrobin, kresoxim-methyl, picoxystrobin, fluxastrobin, dimoxystrobin, pyraclostrobin, trifloxystrobin, coumoxystrobin, fenaminstrobin, pyrametostrobin, triclopyricarb, pyribencarb, pyraoxystrobin, metyltetraprole, mandestrobin, famoxadone, oryzastrobin, enoxastrobin, pyraclostrobin, fluoxastrobin, flufenostrin, flufenoxystrobin, metominostrobin, triclopyricarb; pyriminostrobin, florylpicoxamid, and any combination thereof.
  • the Qol (quinone outside inhibitors) is azoxystrobin. In some embodiments, the Qol (quinone outside inhibitors) is kresoxim -methyl. In some embodiments, the Qol (quinone outside inhibitors) is picoxystrobin. In some embodiments, the Qol (quinone outside inhibitors) is fluxastrobin. In some embodiments, the Qol (quinone outside inhibitors) is dimoxystrobin. In some embodiments, the Qol (quinone outside inhibitors) is pyraclostrobin. In some embodiments, the Qol (quinone outside inhibitors) is trifloxystrobin.
  • the Qol (quinone outside inhibitors) is coumoxystrobin. In some embodiments, the Qol (quinone outside inhibitors) is fenaminstrobin. In some embodiments, the Qol (quinone outside inhibitors) is pyrametostrobin. In some embodiments, the Qol (quinone outside inhibitors) is triclopyricarb. In some embodiments, the Qol (quinone outside inhibitors) is pyribencarb. In some embodiments, the Qol (quinone outside inhibitors) is pyraoxystrobin. In some embodiments, the Qol (quinone outside inhibitors) is metyltetraprole.
  • the Qol (quinone outside inhibitors) is mandestrobin. In some embodiments, the Qol (quinone outside inhibitors) is famoxadone. In some embodiments, the Qol (quinone outside inhibitors) is oryzastrobin. In some embodiments, the Qol (quinone outside inhibitors) is enoxastrobin. In some embodiments, the Qol (quinone outside inhibitors) is flufenostrin. In some embodiments, the Qol (quinone outside inhibitors) is flufenoxystrobin. In some embodiments, the Qol (quinone outside inhibitors) is metominostrobin.
  • the Qol (quinone outside inhibitors) is fluoxastrobin. In some embodiments, the Qol (quinone outside inhibitors) is triclopyricarb. In some embodiments, the Qol (quinone outside inhibitors) is pyriminostrobin. In some embodiments, the Qol (quinone outside inhibitors) is florylpicoxamid
  • the QoSI (quinone outside stigmatellin inhibitors) is ametoctradin.
  • the SDHI (succinate dehydrogenase inhibitors) fungicide is selected from the group consisting of fluxapyroxad, penflufen, bixafen, isopyrazam, sedaxane, benzovindiflupyr, thifluzamide, isofetamid, fluopyram, pydiflumetofen, pyraziflumid, flutolanil, carboxin, boscalid, fluindapyr, penthiopyrad, isoflucypram, inpyrfluxam, furametpyr, benodanil, mepronil, fenfuram, oxycarboxin, pyrapropoyne, flubeneteram, quinofumelin and any combination thereof.
  • the SDHI (succinate dehydrogenase inhibitors) fungicide is fluxapyroxad. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is penflufen. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is bixafen. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is isopyrazam. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is sedaxane. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is benzovindiflupyr.
  • the SDHI (succinate dehydrogenase inhibitors) fungicide is thifluzamide. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is isofetamid. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is fluopyram. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is pydiflumetofen. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is pyraziflumid. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is flutolanil.
  • the SDHI (succinate dehydrogenase inhibitors) fungicide is carboxin. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is boscalid. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is fluindapyr. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is penthiopyrad. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is isoflucypram. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is inpyrfluxam.
  • the SDHI (succinate dehydrogenase inhibitors) fungicide is furametpyr. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is benodanil. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is mepronil. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is fenfuram. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is oxycarboxin. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is quinofumelin.
  • the SDHI (succinate dehydrogenase inhibitors) fungicide is pyrapropoyne. In some embodiments, the SDHI (succinate dehydrogenase inhibitors) fungicide is flubeneteram.
  • the demethylation inhibitor fungicide is selected from the group consisting of Triflumizole, ipconazole, tebuconazole, metconazole, fenbuconazole, bromuconazole, tetraconazole, flutriafol, penconazole, difenoconazole, prothioconazole, epoxiconazole, mefentrifluconazole, triticonazole, imazalil, Fenarimol, Tridemifon, Propiconazole prochloraz, lobutanil, azaconazole, etaconazole, bitertanol, fluquinconazole, myclobutanil, flusilazole, cyproconazole, triadimenol, hexaconazole, simeconazole, imibenconazole, diniconazole, pyrisoxazole and any combination thereof.
  • the demethylation inhibitor fungicide is ipconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is tebuconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is metconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is fenbuconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is bromuconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is tetraconazole.
  • the demethylation inhibitor fungicide is flutriafol. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is penconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is difenoconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is prothioconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is epoxiconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is mefentrifluconazole.
  • the demethylation inhibitor fungicide is triticonazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is imazalil. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is prochloraz. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is lobutanil. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is azaconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is etaconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is bitertanol.
  • the demethylation inhibitor fungicide is fluquinconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is myclobutanil. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is flusilazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is cy proconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is triadimenol. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is hexaconazole.
  • the demethylation inhibitor fungicide is simeconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is imibenconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is diniconazole. In some embodiments, the demethylation inhibitor fungicide (DMI fungicide) is pyrisoxazole.
  • the amine fungicide is selected from the group consisting of fenpropidin, spiroxamine and any combination thereof. In some embodiments, the amine fungicide is a morpholine fungicide.
  • the co-fungicide has low solubility in aromatic solvents (such as Solvesso 200), mineral oils, vegetable/methylated vegetable oils.
  • the solubility of the co-fungicide is at least 5% w/w based on the total weight of the carboxamide solvent of Formula A.
  • R as described in the present invention is an unbranched or branched, saturated or unsaturated.
  • R1 and R2 as described in the present invention are identical or different and an unbranched or branched.
  • the R as described in the present invention is C8- C20 alkyl chain.
  • R1 and R2 are part of cyclic group.
  • Poly Agro A - Poly Agro A is a di-block copolymer, with a total weight of 17000 g/mol, composed of a hydrophobic block (Anchor block- ANCHOR) and a hydrophilic block (Stabilizing block - STAB).
  • the stabilizing, hydrophilic, block is made of sodium 2- A cryloylamino-2 -methylpropane- 1 -sulfonate (AMPS) monomers, which are 77% of the overall monomers in the polymer.
  • the other 23% of the monomers belongs to the anchor, hydrophobic, block which is made of ethyl acrylate monomers.
  • the total amount of monomers in the polymer (degree of polymerization, DPn) is 85 monomers.
  • This polymer may be obtained according to the following procedure. a) Macro CTA
  • Ethanol was removed from the polymer solution using a rotary evaporator. Water was back added to achieve a polymer solution with a final solids content of 40.4%. 2600g of polymer solution was placed in a 5L double jacketed reactor equipped with mechanical agitator and reflux condenser. The pH of the solution was increased to 8,5 using a 50% solution of NaOH. The mixture was heated to 70°C with stirring whereupon 48.4 of a 30% solution of hydrogen peroxide was added in 1 hour. At the end of the additions, the solution was aged for a further 3h00 whereupon it was cooled and discharged.
  • the measured solids content was 37.5%.
  • the polymer is used in the composition of the present invention as a ready aqua polymer solution at concentration of about 30%w/w.
  • Organic phase was prepared by mixing the solvent with the Al and emulsifier (TS 10).
  • Water phase was prepared by mixing water, buffer, antifreeze, and surfactants. The phases were combined and sheared to reduce droplet size. Xanthan gum was added.
  • composition prepared is described in Table 5.
  • Density 1.17g/ml, pH 3-6, viscosity 400-1 OOOcP.
  • Van gel B was added to water and sheared for 10 min to fully disperse the silicate. Buffer, antifreeze, surfactants and antifoam were added and mixed until homogeneous. Folpet was added and milled in a bead mill to reduce the particle size. Xanthan gum was added.
  • Organic phase was prepared by mixing the solvent with the Al and emulsifier (Aerosol OT-SE).
  • Water phase was prepared by mixing water, buffer, antifreeze, and surfactants. The phases were combined and sheared to reduce droplet size. Xanthan gum was added.
  • composition prepared is described in Table 9.
  • Organic phase was prepared by mixing the solvent with the Al and emulsifiers (Aerosol OT-SE, Atlox 4912).
  • Water phase was prepared by mixing water, buffer, antifreeze, and surfactants. The phases were combined and sheared to reduce droplet size. Xanthan gum was added.
  • the two compositions were mixed according to the table 11.
  • compositions of examples 1-3 comprising carboxamide solvent of Formula A were tested before and after accelerated storage (54°C for 2 weeks), and pH remained between 3-6, no sedimentation was observed, dispersion stability (CIPAC MT 180) didn't change significantly, wet sieve residue (CIPAC MT 185) was negligible.
  • Example 4 Captan and fluxapyroxad SE
  • Soprophor FL Acetic acid, Sodium Acetate, Proxel GXL, Propylene glycol, Polyagro A and SAG 1572 were added to water and mixed until homogeneous. Captan was added and milled in a bead mill to reduce the particle size. Xanthan gum was added.
  • Solvent was mixed with Fluxapyroxad and emulsifiers (CO -40, Nansa EVM 63/B) until fully dissolved.
  • Emulsion preparation Water phase was prepared by mixing water and SAG 1572. The phases were combined and sheared to reduce droplet size.
  • Break Thru S 240 was added and mixed until homogeneous.
  • Cab O Sil M5 was added and sheared until uniformly dispersed.
  • Xanthan gum was added.
  • the pH of the composition was tested before and after accelerated storage for 2 weeks at 54° and remained between 3.5 -5.5.
  • composition prepared is described in Table 13.
  • tested product, example 4 was compared to the tank mixture of reference products MERPAN 480 L (captan 480 g a.i./L, SC) and SERCADIS (fluxapyroxad 300 g a.i./L, SC).
  • MERPAN 480 L captan 480 g a.i./L, SC
  • SERCADIS fluxapyroxad 300 g a.i./L, SC.

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Abstract

La présente invention concerne une composition comprenant (1) une quantité de fongicide phtalimide, (2) une quantité d'au moins un co-fongicide, (3) de l'eau et (4) une quantité de solvant carboxamide de formule A. Dans la formule (A), R représente une chaîne alkyle C8 et supérieure, R1 et R2 représentent H et/ou C2-C6-alkyle. La présente invention concerne également des procédés d'utilisation des compositions de l'invention et des procédés de préparation des compositions de l'invention.
EP23762024.0A 2022-08-03 2023-08-03 Composition comprenant un fongicide phtalimide et un co-fongicide Pending EP4565068A1 (fr)

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BRPI0900019A2 (pt) * 2009-01-12 2010-10-19 Rotam Agrochem Int Co Ltd suspoemulsões com base aquosa, processo de preparação e uso desta e método de tratamento de pragas indesejadas em um local
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JP2015509530A (ja) 2012-03-05 2015-03-30 セラディス ベー．フェー． 殺生物剤強化のためのナタマイシン及び／又はホスファイトを含む多価電解質複合体
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BR122022001868B1 (pt) 2015-12-10 2022-09-13 Adama Makhteshim Ltd. Composição de material agrícola, método de controle e prevenção de peste e de aperfeiçoamento do crescimento de planta, processo de preparo da composição de material agrícola e uso de um copolímero em bloco
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WO2024028880A1 (fr) 2024-02-08
TW202415293A (zh) 2024-04-16

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