ES2004807A6 - Procedimiento para la produccion de una composicion farmaceutica nasal de octreotide - Google Patents
Procedimiento para la produccion de una composicion farmaceutica nasal de octreotideInfo
- Publication number
- ES2004807A6 ES2004807A6 ES8702432A ES8702432A ES2004807A6 ES 2004807 A6 ES2004807 A6 ES 2004807A6 ES 8702432 A ES8702432 A ES 8702432A ES 8702432 A ES8702432 A ES 8702432A ES 2004807 A6 ES2004807 A6 ES 2004807A6
- Authority
- ES
- Spain
- Prior art keywords
- compsn
- nasal
- octreotide
- procedure
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DEQANNDTNATYII-OULOTJBUSA-N (4r,7s,10s,13r,16s,19r)-10-(4-aminobutyl)-19-[[(2r)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-n-[(2r,3r)-1,3-dihydroxybutan-2-yl]-7-[(1r)-1-hydroxyethyl]-13-(1h-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxa Chemical group C([C@@H](N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC=2C3=CC=CC=C3NC=2)NC(=O)[C@H](CC=2C=CC=CC=2)NC1=O)C(=O)N[C@H](CO)[C@H](O)C)C1=CC=CC=C1 DEQANNDTNATYII-OULOTJBUSA-N 0.000 title abstract 2
- 108010016076 Octreotide Proteins 0.000 title abstract 2
- 229960002700 octreotide Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hcl hcl Chemical compound Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
- -1 nasal applicator Substances 0.000 abstract 1
- 239000007922 nasal spray Substances 0.000 abstract 1
- 229940097496 nasal spray Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 239000008215 water for injection Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PRODUCCION DE UNA COMPOSICION FARMACEUTICA NASAL DE OCTROTIDE. LA PRESENTE INVENCION TIENE POR OBJETO UN MODO DE ADMINISTRACION NUEVO DE UN ANALOGO DE LA SOMATOSTATINA, LA SMS 201-995, ASI COMO NUEVAS COMPOSICIONES GALENICAS COMPRENDIENDO DICHO ANALOGO.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868620035A GB8620035D0 (en) | 1986-08-18 | 1986-08-18 | Organic compounds |
| GB868626821A GB8626821D0 (en) | 1986-11-10 | 1986-11-10 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2004807A6 true ES2004807A6 (es) | 1989-02-01 |
Family
ID=26291187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8702432A Expired ES2004807A6 (es) | 1986-08-18 | 1987-08-18 | Procedimiento para la produccion de una composicion farmaceutica nasal de octreotide |
Country Status (24)
| Country | Link |
|---|---|
| KR (1) | KR880002537A (es) |
| AT (1) | AT396331B (es) |
| AU (2) | AU612589B2 (es) |
| BE (1) | BE1001748A4 (es) |
| CA (1) | CA1322331C (es) |
| CH (1) | CH672252A5 (es) |
| CS (1) | CS411491A3 (es) |
| DE (1) | DE3726517A1 (es) |
| DK (1) | DK428287A (es) |
| ES (1) | ES2004807A6 (es) |
| FI (1) | FI93307C (es) |
| FR (1) | FR2602680B1 (es) |
| GR (1) | GR871289B (es) |
| HK (1) | HK80493A (es) |
| HU (1) | HU200940B (es) |
| IE (1) | IE60761B1 (es) |
| IL (1) | IL83572A (es) |
| IT (1) | IT1222510B (es) |
| LU (1) | LU86971A1 (es) |
| NL (1) | NL8701874A (es) |
| NO (1) | NO175519C (es) |
| NZ (1) | NZ221473A (es) |
| PT (1) | PT85545B (es) |
| SE (1) | SE8703183L (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003216084A1 (en) | 2002-01-22 | 2003-09-02 | New York University | Methods for therapeutic treatment of benign prostatic hypertrophy (bph) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6034925B2 (ja) * | 1979-07-31 | 1985-08-12 | 帝人株式会社 | 持続性鼻腔用製剤およびその製造法 |
| DE3062075D1 (en) * | 1979-11-27 | 1983-03-24 | Sandoz Ag | Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use |
| US4451394A (en) * | 1982-10-25 | 1984-05-29 | American Home Products Corporation | Dodecapeptides preventing glucose and triglyceride assimilation |
| JPS59163313A (ja) * | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
| US4505897A (en) * | 1983-04-18 | 1985-03-19 | The Administrators Of The Tulane Educational Fund | Cyclic pentapeptides displaying somatostatin antagonism and method of treatment of mammals therewith |
| GB8514090D0 (en) * | 1985-06-04 | 1985-07-10 | Sandoz Ltd | Organic compounds |
| US4612302A (en) * | 1983-11-14 | 1986-09-16 | Brigham And Women's Hospital | Clinical use of somatostatin analogues |
| JPS60224616A (ja) * | 1984-04-24 | 1985-11-09 | Teijin Ltd | 経鼻投与用組成物 |
| US4725577A (en) * | 1985-04-25 | 1988-02-16 | Administrators Of The Tulane Educational Fund | Biologically active lysine containing octapeptides |
| JPH085913B2 (ja) * | 1985-09-12 | 1996-01-24 | ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド | 治療用ソマトスタチン同族体 |
-
1987
- 1987-08-08 DE DE19873726517 patent/DE3726517A1/de not_active Ceased
- 1987-08-10 HU HU873618A patent/HU200940B/hu not_active IP Right Cessation
- 1987-08-10 NL NL8701874A patent/NL8701874A/nl not_active Application Discontinuation
- 1987-08-10 BE BE8700893A patent/BE1001748A4/fr not_active IP Right Cessation
- 1987-08-10 FR FR8711402A patent/FR2602680B1/fr not_active Expired - Fee Related
- 1987-08-14 LU LU86971A patent/LU86971A1/fr unknown
- 1987-08-14 CH CH3134/87A patent/CH672252A5/de not_active IP Right Cessation
- 1987-08-17 PT PT85545A patent/PT85545B/pt not_active IP Right Cessation
- 1987-08-17 NO NO873452A patent/NO175519C/no unknown
- 1987-08-17 FI FI873548A patent/FI93307C/fi not_active IP Right Cessation
- 1987-08-17 GR GR871289A patent/GR871289B/el unknown
- 1987-08-17 IE IE218787A patent/IE60761B1/en not_active IP Right Cessation
- 1987-08-17 AT AT0206087A patent/AT396331B/de not_active IP Right Cessation
- 1987-08-17 DK DK428287A patent/DK428287A/da unknown
- 1987-08-17 AU AU77120/87A patent/AU612589B2/en not_active Ceased
- 1987-08-17 NZ NZ221473A patent/NZ221473A/xx unknown
- 1987-08-17 IL IL83572A patent/IL83572A/xx not_active IP Right Cessation
- 1987-08-17 KR KR1019870008981A patent/KR880002537A/ko not_active Ceased
- 1987-08-17 SE SE8703183A patent/SE8703183L/ not_active Application Discontinuation
- 1987-08-17 CA CA000544704A patent/CA1322331C/en not_active Expired - Fee Related
- 1987-08-18 IT IT21670/87A patent/IT1222510B/it active
- 1987-08-18 ES ES8702432A patent/ES2004807A6/es not_active Expired
-
1991
- 1991-10-09 AU AU85689/91A patent/AU637530B2/en not_active Ceased
- 1991-12-27 CS CS914114A patent/CS411491A3/cs unknown
-
1993
- 1993-08-05 HK HK804/93A patent/HK80493A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20001204 |