ES2007328A4 - Derivados de dihidropiridazinona, proceso de fabricacion y medicamentos con sus combinaciones - Google Patents

Derivados de dihidropiridazinona, proceso de fabricacion y medicamentos con sus combinaciones

Info

Publication number
ES2007328A4
ES2007328A4 ES88101620T ES88101620T ES2007328A4 ES 2007328 A4 ES2007328 A4 ES 2007328A4 ES 88101620 T ES88101620 T ES 88101620T ES 88101620 T ES88101620 T ES 88101620T ES 2007328 A4 ES2007328 A4 ES 2007328A4
Authority
ES
Spain
Prior art keywords
dihydropiridazinone
medicines
derivatives
combinations
manufacturing process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ES88101620T
Other languages
English (en)
Inventor
Helmut Schickaneder
Volker Pfahlert
Peter Morsdorf
Kurt Henning Ahrens
Heidrun Engler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heumann Pharma GmbH and Co
Original Assignee
Heumann Pharma GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Pharma GmbH and Co filed Critical Heumann Pharma GmbH and Co
Publication of ES2007328A4 publication Critical patent/ES2007328A4/es
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE DESCRIBEN NUEVOS DERIVADOS DE DIHIDROPIRIDAZINONA DE FORMULA GENERAL (I) ASI COMO UN PROCESO PARA SU PRODUCCION Y MEDICAMENTOS QUE CONTIENEN ESTOS COMPUESTOS. ESTOS COMPUESTOS REPRESENTAN SUSTANCIAS EFECTIVAS POSITIVAS INOTROPAS CON UN PERFIL TERAPEUTICO MEJORADO.
ES88101620T 1987-08-26 1988-02-04 Derivados de dihidropiridazinona, proceso de fabricacion y medicamentos con sus combinaciones Pending ES2007328A4 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873728491 DE3728491A1 (de) 1987-08-26 1987-08-26 Dihydropyridazinon-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ES2007328A4 true ES2007328A4 (es) 1989-06-16

Family

ID=6334541

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88101620T Pending ES2007328A4 (es) 1987-08-26 1988-02-04 Derivados de dihidropiridazinona, proceso de fabricacion y medicamentos con sus combinaciones

Country Status (14)

Country Link
US (1) US4921856A (es)
EP (1) EP0304534A1 (es)
JP (1) JPS6468360A (es)
KR (1) KR890003736A (es)
AU (1) AU598636B2 (es)
DE (1) DE3728491A1 (es)
DK (1) DK170788A (es)
ES (1) ES2007328A4 (es)
GR (1) GR890300066T1 (es)
HU (1) HUT57737A (es)
IL (1) IL85387A0 (es)
NZ (1) NZ223683A (es)
PT (1) PT87115A (es)
ZA (1) ZA88950B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3804490A1 (de) * 1988-02-12 1989-08-24 Heumann Pharma Gmbh & Co Substituierte 6-phenyldihydro-3(2h)-pyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3814057A1 (de) * 1988-04-26 1989-11-09 Heumann Pharma Gmbh & Co 6-oxo-pyridazinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
DE3913597A1 (de) * 1989-04-25 1990-11-08 Heumann Pharma Gmbh & Co Diazinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5100892A (en) * 1990-11-13 1992-03-31 Glaxo Inc. Dihydropyridine vasodilator agents
US5504064A (en) * 1991-04-10 1996-04-02 Oklahoma Medical Research Foundation Treatment of bleeding with modified tissue factor in combination with an activator of FVII
IL118631A (en) * 1995-06-27 2002-05-23 Tanabe Seiyaku Co History of pyridazinone and processes for their preparation
UA95644C2 (ru) * 2006-07-25 2011-08-25 Сефалон, Инк. Пиридазиноновые производные, фармацевтическая композиция и способ лечения заболеваний
JP5688367B2 (ja) * 2008-08-29 2015-03-25 トポターゲット・アクティーゼルスカブＴｏｐｏＴａｒｇｅｔ Ａ／Ｓ 新規なウレアおよびチオウレア誘導体
CA2879454A1 (en) 2012-07-19 2014-01-23 Drexel University Novel sigma receptor ligands and methods of modulating cellular protein homeostasis using same
WO2019089902A1 (en) 2017-11-01 2019-05-09 Drexel University Compounds, compositions, and methods for treating diseases
CN110117257B (zh) * 2018-02-05 2022-12-06 安徽省新星药物开发有限责任公司 一种含胍基的p2y12受体拮抗剂、制备方法及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791539A (fr) * 1971-11-19 1973-05-17 Basf Ag Dihydropyridazones, leur preparation et leurs utilisations therapeutiques
EP0107735B1 (en) * 1981-10-20 1988-10-19 Mitsui Toatsu Kagaku Kabushiki Kaisha Novel pyridazinone derivatives
JPS60197672A (ja) * 1984-03-16 1985-10-07 Mitsubishi Chem Ind Ltd ビリダジノン誘導体またはその塩類
JPS6193169A (ja) * 1984-10-12 1986-05-12 Sankyo Co Ltd ピリダジノン誘導体及びその製法

Also Published As

Publication number Publication date
IL85387A0 (en) 1988-07-31
KR890003736A (ko) 1989-04-17
GR890300066T1 (en) 1989-09-29
PT87115A (pt) 1989-09-14
NZ223683A (en) 1990-04-26
DK170788A (da) 1989-02-27
AU1170788A (en) 1989-03-02
DE3728491A1 (de) 1989-03-09
AU598636B2 (en) 1990-06-28
JPS6468360A (en) 1989-03-14
EP0304534A1 (de) 1989-03-01
US4921856A (en) 1990-05-01
HUT57737A (en) 1991-12-30
DK170788D0 (da) 1988-03-28
ZA88950B (en) 1988-08-11

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