ES537401A0 - Un procedimiento para producir derivados de penem - Google Patents

Un procedimiento para producir derivados de penem

Info

Publication number
ES537401A0
ES537401A0 ES537401A ES537401A ES537401A0 ES 537401 A0 ES537401 A0 ES 537401A0 ES 537401 A ES537401 A ES 537401A ES 537401 A ES537401 A ES 537401A ES 537401 A0 ES537401 A0 ES 537401A0
Authority
ES
Spain
Prior art keywords
procedure
penem derivatives
producing
producing penem
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES537401A
Other languages
English (en)
Other versions
ES8603491A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ES537401A0 publication Critical patent/ES537401A0/es
Publication of ES8603491A1 publication Critical patent/ES8603491A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pens And Brushes (AREA)
ES537401A 1983-11-07 1984-11-06 Un procedimiento para producir derivados de penem Expired ES8603491A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/549,535 US4584133A (en) 1983-11-07 1983-11-07 Process for the production of penems

Publications (2)

Publication Number Publication Date
ES537401A0 true ES537401A0 (es) 1985-12-16
ES8603491A1 ES8603491A1 (es) 1985-12-16

Family

ID=24193398

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537401A Expired ES8603491A1 (es) 1983-11-07 1984-11-06 Un procedimiento para producir derivados de penem

Country Status (11)

Country Link
US (1) US4584133A (es)
EP (1) EP0146730B1 (es)
JP (1) JPH0631255B2 (es)
AT (1) ATE54452T1 (es)
CA (1) CA1234099A (es)
DE (1) DE3482691D1 (es)
ES (1) ES8603491A1 (es)
FI (1) FI82697C (es)
HU (1) HU194569B (es)
IE (1) IE57609B1 (es)
IL (1) IL73228A (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
DE3572490D1 (en) * 1984-02-02 1989-09-28 Schering Corp Hydrazone substituted penems
DK39886D0 (da) * 1986-01-27 1986-01-27 Hans Goeran Magnusson Hydroxybeskyttelsesgrupper
US4806637A (en) * 1986-03-17 1989-02-21 Schering Corporation 6-(Hydroxyethyl)-2-(heterocyclylthio)-penem-3-carboxylates
US4767853A (en) * 1986-07-21 1988-08-30 Schering Corporation Synthesis of 1-(allyloxycarbonyl)-methyl-3-(hydroxyethyl)-4-beta-naphthoxythiocarbonylthio-2-azetidinones and hydroxy protected analogs thereof
US5053502A (en) * 1986-07-21 1991-10-01 Schering Corporation Anhydro penicillin derivatives
US5075438A (en) * 1986-07-21 1991-12-24 Schering Corporation Synthesis of azetidinones
US4948885A (en) * 1986-07-21 1990-08-14 Schering-Plough Corp. Synthesis of azetidinones
US4876338A (en) * 1986-07-21 1989-10-24 Schering Corporation Synthesis of azetidinones using CuCl
LU87271A1 (fr) * 1988-07-08 1990-02-07 Oreal Nouveaux derives insatures liposolubles des benzalmalonates et leur utilisation en tant qu'absorbeurs du rayonnement ultra-violet en cosmetique
US5191075A (en) * 1988-10-19 1993-03-02 Pfizer Inc Process for the preparation of penems
US4895940A (en) * 1988-10-19 1990-01-23 Pfizer Inc. Process for the preparation of penems
US4992543A (en) * 1988-10-19 1991-02-12 Pfizer Inc. Penem derivatives
US4876365A (en) * 1988-12-05 1989-10-24 Schering Corporation Intermediate compounds for preparing penems and carbapenems

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003960B1 (de) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
ATE28648T1 (de) * 1982-03-26 1987-08-15 Hoechst Uk Ltd 7-oxo-4-thia-1-azabicyclo(3,2,0)heptan-derivate
US4443373A (en) * 1982-03-30 1984-04-17 Schering Corporation Process for the production of antibiotic penems
EP0110280B1 (en) * 1982-11-29 1994-10-12 Schering Corporation Process for the production of penem compounds
US4610823A (en) * 1983-01-25 1986-09-09 Merck & Co., Inc. Process for preparing substituted 2-thioxopenams and 2-substituted thiopenems

Also Published As

Publication number Publication date
IL73228A (en) 1989-03-31
HU194569B (en) 1988-02-29
EP0146730A1 (en) 1985-07-03
DE3482691D1 (de) 1990-08-16
FI844325A0 (fi) 1984-11-05
FI82697B (fi) 1990-12-31
ES8603491A1 (es) 1985-12-16
EP0146730B1 (en) 1990-07-11
JPH0631255B2 (ja) 1994-04-27
CA1234099A (en) 1988-03-15
US4584133A (en) 1986-04-22
IE57609B1 (en) 1993-01-27
IE842848L (en) 1985-05-07
FI844325L (fi) 1985-05-08
ATE54452T1 (de) 1990-07-15
FI82697C (fi) 1991-04-10
IL73228A0 (en) 1985-01-31
JPS60120885A (ja) 1985-06-28
HUT40134A (en) 1986-11-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001102