ES2009208A6 - Un metodo para producir un ester de benzoilo. - Google Patents

Un metodo para producir un ester de benzoilo.

Info

Publication number
ES2009208A6
ES2009208A6 ES8600593A ES8600593A ES2009208A6 ES 2009208 A6 ES2009208 A6 ES 2009208A6 ES 8600593 A ES8600593 A ES 8600593A ES 8600593 A ES8600593 A ES 8600593A ES 2009208 A6 ES2009208 A6 ES 2009208A6
Authority
ES
Spain
Prior art keywords
formula
compound
lower alkylene
single bond
benzoil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600593A
Other languages
English (en)
Inventor
Setsuro Fujii
Eizou Hattori
Mitsuteru Hirata
Koichiro Watanabe
Tomio Ohta
Nobuo Yokoo
Masahiko Nagakura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Publication of ES2009208A6 publication Critical patent/ES2009208A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UN METODO PARA PRODUCIR UN ESTER DE BENZOILO. COMPRENDE: (1) (A) HACER REACCIONAR ACIDO P-INTROBENZOICO CON (III) PARA DAR (IV), (B) REDUCIR (IV) PARA PRODUCIR (IX), (C) SOMETER (IX) A REACCION DE GUANIDILACION PARA OBTENER (I); O (2) HACER REACCIONAR ACIDO P-GUANIDINOBENZOICO CON (III) PARA DAR (I). EN ESTAS FORMULAS LOS DIFERENTES SIMBOLOS REPRESENTAN RADICALES ORGANICOS. LOS ESTERES DE BENZOILO DE LA FORMULA (I) TIENEN POTENTE ACTIVIDAD ANTITRIPSINA, ACTIVIDAD ANTITROMBINA Y ACTIVIDAD ANTICOAGULANTE CON BAJA TOXICIDAD Y SON UTILES COMO MEDICAMENTO PARA EL TRATAMIENTO DE PANCREATITIS Y COAGULACION INTRAVASCULAR DISEMINADA.
ES8600593A 1985-07-26 1986-07-24 Un metodo para producir un ester de benzoilo. Expired ES2009208A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16523685 1985-07-26

Publications (1)

Publication Number Publication Date
ES2009208A6 true ES2009208A6 (es) 1989-09-16

Family

ID=15808446

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600593A Expired ES2009208A6 (es) 1985-07-26 1986-07-24 Un metodo para producir un ester de benzoilo.

Country Status (6)

Country Link
JP (1) JPS62103058A (es)
KR (1) KR870001154A (es)
CN (1) CN86105509A (es)
DK (1) DK353786A (es)
ES (1) ES2009208A6 (es)
HU (1) HU196590B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101981347B1 (ko) * 2011-09-15 2019-05-22 아스텔라스세이야쿠 가부시키가이샤 구아니디노벤조산 화합물

Also Published As

Publication number Publication date
CN86105509A (zh) 1987-02-11
DK353786D0 (da) 1986-07-25
JPS62103058A (ja) 1987-05-13
HUT41378A (en) 1987-04-28
DK353786A (da) 1987-01-27
HU196590B (en) 1988-12-28
KR870001154A (ko) 1987-03-11

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980601