ES2013124A6 - Un metodo para fabricar un dosificador hermeticamente cerrado y procedimiento para preparar una solucion acuosa de cromoglicato de sodio y clorbutol. - Google Patents
Un metodo para fabricar un dosificador hermeticamente cerrado y procedimiento para preparar una solucion acuosa de cromoglicato de sodio y clorbutol.Info
- Publication number
- ES2013124A6 ES2013124A6 ES898901035A ES8901035A ES2013124A6 ES 2013124 A6 ES2013124 A6 ES 2013124A6 ES 898901035 A ES898901035 A ES 898901035A ES 8901035 A ES8901035 A ES 8901035A ES 2013124 A6 ES2013124 A6 ES 2013124A6
- Authority
- ES
- Spain
- Prior art keywords
- chlorbutol
- dose dispenser
- hermetically sealed
- procedure
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 6
- OSASVXMJTNOKOY-UHFFFAOYSA-N chlorobutanol Chemical compound CC(C)(O)C(Cl)(Cl)Cl OSASVXMJTNOKOY-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004926 chlorobutanol Drugs 0.000 title abstract 3
- IMZMKUWMOSJXDT-UHFFFAOYSA-N cromoglycic acid Chemical compound O1C(C(O)=O)=CC(=O)C2=C1C=CC=C2OCC(O)COC1=CC=CC2=C1C(=O)C=C(C(O)=O)O2 IMZMKUWMOSJXDT-UHFFFAOYSA-N 0.000 title abstract 3
- 239000007864 aqueous solution Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000243 solution Substances 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000414 obstructive effect Effects 0.000 abstract 1
- 230000002441 reversible effect Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000008174 sterile solution Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
METODO PARA FABRICAR UN DOSIFICADOR HERMETICAMENTE CERRADO Y PROCEDIMIENTO PARA PREPARAR UNA SOLUCION ACUOSA DE CROMOGLICATO DE SODIO Y CLORBUTOL. EL METODO COMPRENDE INTRODUCIR EN EL DOSIFICADOR PRIMERO UNA SOLUCION ESTERIL DE UN MEDICAMENTO DE INHALACION Y SEGUIDAMENTE UN GAS PRESURIZADO A UNA PRESION DE 30 A 100 KPA, INTRODUCIENDOSE LA SOLUCION EN CONDICIONES ESTERILES Y/O ESTERILIZANDOSE EL DOSIFICADOR DESPUES DE HABER INTRODUCIDO EN EL LA SOLUCION Y EL GAS. EL PROCEDIMIENTO CONSISTE EN DISOLVER CLORBUTOL EN AGUA DESTILADA A UNA TEMPERATURA DE 20 A 60GC, EN UN RECIPIENTE HERMETICAMENTE CERRADO O SIMPLEMENTE TAPADO, Y MEZCLAR LA SOLUCION RESULTANTE CON CROMOGLICATO DE SODIO SOLIDO. EL INVENTO ES UTIL PARA TRATAR LA ENFERMEDAD OBSTRUCTIVA REVERSIBLE DE LAS VIAS RESPIRATORIAS.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888806818A GB8806818D0 (en) | 1988-03-22 | 1988-03-22 | Pharmaceutical formulation |
| GB888819490A GB8819490D0 (en) | 1988-08-16 | 1988-08-16 | Pharmaceutical devices |
| EP89302340A EP0338670B1 (en) | 1988-03-22 | 1989-03-09 | Pharmaceutical Compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2013124A6 true ES2013124A6 (es) | 1990-04-16 |
Family
ID=27232656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES898901035A Expired - Fee Related ES2013124A6 (es) | 1988-03-22 | 1989-03-22 | Un metodo para fabricar un dosificador hermeticamente cerrado y procedimiento para preparar una solucion acuosa de cromoglicato de sodio y clorbutol. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2013124A6 (es) |
-
1989
- 1989-03-22 ES ES898901035A patent/ES2013124A6/es not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20090323 |